Cas Simons

7.4k citations

73 papers · 2.8k indexed · 1 hit paper · h-index 25

Impact in

Cancer Research top 2%
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
Molecular Biology top 5%
- RNA modifications and cancer
- RNA Research and Splicing
- RNA regulation and disease
- RNA and protein synthesis mechanisms
- Circular RNAs in diseases
- Renal and related cancers

Papers in ⓘ

Molecular Biology 58
- RNA regulation and disease 21
- RNA Research and Splicing 14
- RNA modifications and cancer 14
- RNA and protein synthesis mechanisms 13
- Mitochondrial Function and Pathology 10
Genetics 17
- Genomics and Rare Diseases 5

Co-authors: John S. Mattick (7 shared papers)Ryan J. Taft (19 shared papers)Tim R. Mercer (3 shared papers)Marcel E. Dinger (2 shared papers)Giulia Soldà (2 shared papers)Sean M. Grimmond (3 shared papers)Adeline Vanderver (20 shared papers)Ken C. Pang (1 shared paper)
Journals: Human Molecular Genetics (5 papers)Neurology (3 papers)Brain (3 papers)PLoS ONE (3 papers)Developmental Dynamics (2 papers)
Partner nations: Australia United States Netherlands

In The Last Decade

Cas Simons

68 papers receiving 2.7k citations

Hit Papers

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Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation 2008 · 605 citations

Peers

Countries citing papers authored by Cas Simons

Since Specialization

Citations

This map shows the geographic impact of Cas Simons's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Cas Simons with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Cas Simons more than expected).

Fields of papers citing papers by Cas Simons

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Cas Simons. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Cas Simons. The network helps show where Cas Simons may publish in the future.

Co-authors

The 25 scholars most cited alongside Cas Simons, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Cas Simons Line = papers co-authored together Cas Simons links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 73 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation Genome Research ·Marcel E. Dinger, Paulo Amaral, Tim R. Mercer, Ken C. Pang, Stephen J. Bruce, Brooke Gardiner, Marjan Askarian-Amiri, Kelin Ru, Giulia Soldà, Cas Simons, Susan M. Sunkin, Mark L. Crowe, Sean M. Grimmond, Andrew C. Perkins, John S. Mattick Hit paper breakdown →	2008	605
2	Expression of distinct RNAs from 3′ untranslated regions Nucleic Acids Research ·Tim R. Mercer, Dagmar Wilhelm, Marcel E. Dinger, Giulia Soldà, Darren Korbie, Evgeny A. Glazov, Vy Truong, Maren Schwenke, Cas Simons, Klaus I. Matthaei, Robert Saint, Peter Koopman, John S. Mattick	2010	176
3	Patient-iPSC-Derived Kidney Organoids Show Functional Validation of a Ciliopathic Renal Phenotype and Reveal Underlying Pathogenetic Mechanisms The American Journal of Human Genetics ·Thomas Forbes, Sara E. Howden, Kynan T. Lawlor, Belinda Phipson, Jovana Maksimovic, Lorna J. Hale, Sean B. Wilson, Catherine Quinlan, Gladys Ho, Katherine Holman, Bruce Bennetts, Joanna Crawford, Peter Trnka, Alicia Oshlack, Chirag Patel, Andrew J. Mallett, Cas Simons, Melissa H. Little	2018	155
4	Nuclear-localized tiny RNAs are associated with transcription initiation and splice sites in metazoans Nature Structural & Molecular Biology ·Ryan J. Taft, Cas Simons, Satu Nahkuri, Harald Oey, Darren Korbie, Tim R. Mercer, Jeff Holst, William Ritchie, Justin Wong, John E.J. Rasko, Daniel S. Rokhsar, Bernard M. Degnan, John S. Mattick	2010	128
5	A clinical approach to the diagnosis of patients with leukodystrophies and genetic leukoencephelopathies Molecular Genetics and Metabolism ·Sumit Parikh, Geneviève Bernard, Richard J. Leventer, Marjo S. van der Knaap, Johan Van Hove, Amy Pizzino, Nathan H. McNeill, Guy Helman, Cas Simons, Johanna Schmidt, William B. Rizzo, Marc C. Patterson, Ryan J. Taft, Adeline Vanderver	2014	123
6	Psychophysical and Neurobiological Evidence that the Oral Sensation Elicited by Carbonated Water is of Chemogenic Origin Chemical Senses ·J.-M. Dessirier, Cas Simons, Mirela Iodi Carstens, Michael O’Mahony, E. Carstens	2000	115
7	Transposon-free regions in mammalian genomes Genome Research ·Cas Simons, Michael Pheasant, Igor V. Makunin, John S. Mattick	2005	97
8	First and second phases of biphasic fever: two sequential stages of the sickness syndrome? American Journal of Physiology-Regulatory, Integrative and Comparative Physiology ·Andrej A. Romanovsky, V. A. Kulchitsky, Н. В. Акулич, STANISLAW V. KOULCHITSKY, Cas Simons, D. I. Sessler, Valery N. Gourine	1996	97
9	Mural lymphatic endothelial cells regulate meningeal angiogenesis in the zebrafish Nature Neuroscience ·Neil I. Bower, Katarzyna Koltowska, Cathy Pichol-Thievend, Isaac Virshup, Scott Paterson, Anne K. Lagendijk, Weili Wang, Benjamin W. Lindsey, Stephen J. Bent, Sungmin Baek, Maria Cristina Rondon-Galeano, Daniel Hurley, Naoki Mochizuki, Cas Simons, Mathias François, Christine A. Wells, Jan Kaslin, Benjamin M. Hogan	2017	87
10	Hypomyelination with atrophy of the basal ganglia and cerebellum: further delineation of the phenotype and genotype–phenotype correlation Brain ·Eline M. Hamilton, Emiel Polder, Adeline Vanderver, Sakkubai Naidu, Raphael Schiffmann, Kate Fisher, Ana Raguž, Luba Blumkin, Carola G.M. van Berkel, Quinten Waisfisz, Cas Simons, Ryan J. Taft, Truus E. M. Abbink, Nicole I. Wolf, Marjo S. van der Knaap	2014	77
11	Evolution, biogenesis and function of promoter-associated RNAs Cell Cycle ·Ryan J. Taft, Craig D. Kaplan, Cas Simons, John S. Mattick	2009	71
12	Whole exome sequencing in family trios reveals de novo mutations in PURA as a cause of severe neurodevelopmental delay and learning disability Journal of Medical Genetics ·David Hunt, Richard J. Leventer, Cas Simons, Ryan J. Taft, Kathryn J. Swoboda, M. L. Gawne‐Cain, (unknown), Alex Magee, Peter D. Turnpenny, Diana Baralle	2014	71
13	A recurrent de novo mutation in TMEM106B causes hypomyelinating leukodystrophy Brain ·Cas Simons, David A. Dyment, Stephen J. Bent, Joanna Crawford, Marc D’Hooghe, Alfried Kohlschütter, Sunita Venkateswaran, Guy Helman, Bwee Tien Poll‐The, Christine Makowski, Yoko Ito, Kristin D. Kernohan, Taila Hartley, Quinten Waisfisz, Ryan J. Taft, Marjo S. van der Knaap, Nicole I. Wolf	2017	59
14	TUBB4A mutations result in specific neuronal and oligodendrocytic defects that closely match clinically distinct phenotypes Human Molecular Genetics ·Julian Curiel, Guillermo Rodríguez Bey, Asako Takanohashi, Marianna Bugiani, Xiaoqin Fu, Nicole I. Wolf, Bruce Nmezi, Raphael Schiffmann, Mona Bugaighis, Tyler Mark Pierson, Guy Helman, Cas Simons, Marjo S. van der Knaap, Judy Liu, Quasar Saleem Padiath, Adeline Vanderver	2017	53
15	Exome sequencing in developmental eye disease leads to identification of causal variants in GJA8, CRYGC, PAX6 and CYP1B1 European Journal of Human Genetics ·Ivan Prokudin, Cas Simons, John Grigg, Rebecca Storen, Vikrant Kumar, Zai Yang Phua, James E. Smith, Maree Flaherty, Sonia Dávila, Robyn V. Jamieson	2013	52
16	mafba is a downstream transcriptional effector of Vegfc signaling essential for embryonic lymphangiogenesis in zebrafish Genes & Development ·Katarzyna Koltowska, Scott Paterson, Neil I. Bower, Gregory J. Baillie, Anne K. Lagendijk, Jonathan W. Astin, Huijun Chen, Mathias François, Philip S. Crosier, Ryan J. Taft, Cas Simons, K. A. Smith, Benjamin M. Hogan	2015	49
17	Identification of a Novel de Novo p.Phe932Ile KCNT1 Mutation in a Patient With Leukoencephalopathy and Severe Epilepsy Pediatric Neurology ·Adeline Vanderver, Cas Simons, Johanna Schmidt, Philip Pearl, Miriam Bloom, Bennett Lavenstein, David S. Miller, Sean M. Grimmond, Ryan J. Taft	2013	49
18	DARS -associated leukoencephalopathy can mimic a steroid-responsive neuroinflammatory disorder Neurology ·Nicole I. Wolf, Camilo Toro, Ilya Kister, Kartikasalwah Abd Latif, Richard J. Leventer, Amy Pizzino, Cas Simons, Truus E. M. Abbink, Ryan J. Taft, Marjo S. van der Knaap, Adeline Vanderver	2014	49
19	NF-κB inducing kinase (NIK) modulates melanoma tumorigenesis by regulating expression of pro-survival factors through the β-catenin pathway Oncogene ·Yee Mon Thu, Yan Ru Su, Jinming Yang, Ryan Splittgerber, Sijia Na, Alan S. Boyd, Claudio A. Mosse, Cas Simons, Ann Richmond	2011	40
20	TUBB4A de novo mutations cause isolated hypomyelination Neurology ·Amy Pizzino, Tyler Mark Pierson, Yiran Guo, Guy Helman, Sebastian Fortini, Kether Guerrero, Sulagna C. Saitta, Jennifer L. Murphy, Quasar Saleem Padiath, Yi Xie, Håkon Håkonarson, Xun Xu, Tara Funari, Michelle Fox, Ryan J. Taft, Marjo S. van der Knaap, Geneviève Bernard, Raphael Schiffmann, Cas Simons, Adeline Vanderver	2014	39

About Cas Simons

Cas Simons is a scholar working on Molecular Biology, Genetics, Neurology, Cancer Research and Clinical Biochemistry, having authored 73 papers that have together received 2.8k indexed citations. Recurring topics across this work include RNA regulation and disease (21 papers), RNA Research and Splicing (14 papers), RNA modifications and cancer (14 papers), RNA and protein synthesis mechanisms (13 papers), Mitochondrial Function and Pathology (10 papers), MicroRNA in disease regulation (5 papers), Lymphatic System and Diseases (5 papers) and Genomics and Rare Diseases (5 papers). The work is most often cited by research in Cancer Research (847 citations), Molecular Biology (2.0k citations), Neurology (138 citations), Sensory Systems (69 citations) and Genetics (368 citations). Cas Simons has collaborated with scholars based in Australia, United States and Netherlands. Frequent co-authors include John S. Mattick, Ryan J. Taft, Tim R. Mercer, Marcel E. Dinger, Giulia Soldà, Sean M. Grimmond, Adeline Vanderver, Ken C. Pang, Mark L. Crowe and Stephen J. Bruce. Their work appears in journals such as Human Molecular Genetics, Neurology, Brain, PLoS ONE and Developmental Dynamics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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