Caroline J. Breitbach

6.1k total citations · 1 hit paper
51 papers, 3.5k citations indexed

About

Caroline J. Breitbach is a scholar working on Genetics, Oncology and Molecular Biology. According to data from OpenAlex, Caroline J. Breitbach has authored 51 papers receiving a total of 3.5k indexed citations (citations by other indexed papers that have themselves been cited), including 42 papers in Genetics, 27 papers in Oncology and 19 papers in Molecular Biology. Recurrent topics in Caroline J. Breitbach's work include Virus-based gene therapy research (42 papers), CAR-T cell therapy research (25 papers) and Cancer Research and Treatments (19 papers). Caroline J. Breitbach is often cited by papers focused on Virus-based gene therapy research (42 papers), CAR-T cell therapy research (25 papers) and Cancer Research and Treatments (19 papers). Caroline J. Breitbach collaborates with scholars based in Canada, United States and South Korea. Caroline J. Breitbach's co-authors include John C. Bell, David H. Kirn, Brian D. Lichty, David F. Stojdl, James M. Burke, Tae-Ho Hwang, Anne Moon, Theresa Falls, Kelley A. Parato and Manijeh Daneshmand and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Clinical Oncology.

In The Last Decade

Caroline J. Breitbach

49 papers receiving 3.5k citations

Hit Papers

1 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Going viral with cancer immunotherapy

2014 481 citations Brian D. Lichty, Caroline J. Breitbach et al. Nature reviews. Cancer profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Caroline J. Breitbach Canada	28	2.5k	2.1k	1.2k	1.1k	538	51	3.5k
Rosa María Díaz United States	39	2.5k 1.0×	2.0k 0.9×	1.6k 1.2×	1.2k 1.2×	440 0.8×	97	3.7k
Steve H. Thorne United States	28	2.1k 0.9×	1.7k 0.8×	1.3k 1.0×	833 0.8×	569 1.1×	48	3.2k
Terry Hermiston United States	33	2.7k 1.1×	1.5k 0.7×	2.4k 1.9×	553 0.5×	489 0.9×	61	3.8k
Kelley A. Parato Canada	15	1.7k 0.7×	1.2k 0.5×	815 0.7×	442 0.4×	350 0.7×	17	2.0k
Matt Coffey United States	35	2.9k 1.2×	2.0k 0.9×	1.3k 1.0×	643 0.6×	854 1.6×	98	3.6k
Igor P. Dmitriev United States	35	3.2k 1.3×	1.9k 0.9×	2.7k 2.1×	397 0.4×	438 0.8×	83	4.1k
Anna Kanerva Finland	39	3.8k 1.5×	3.1k 1.5×	2.5k 2.0×	695 0.7×	995 1.8×	125	4.7k
Guy Ungerechts Germany	27	1.5k 0.6×	1.2k 0.6×	782 0.6×	410 0.4×	228 0.4×	62	2.3k
Frederick J. Kohlhapp United States	14	1.1k 0.5×	1.3k 0.6×	919 0.7×	814 0.8×	260 0.5×	27	2.3k
Phonphimon Wongthida United States	21	1.2k 0.5×	866 0.4×	710 0.6×	507 0.5×	162 0.3×	31	1.8k

Countries citing papers authored by Caroline J. Breitbach

Since Specialization

Citations

This map shows the geographic impact of Caroline J. Breitbach's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Caroline J. Breitbach with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Caroline J. Breitbach more than expected).

Fields of papers citing papers by Caroline J. Breitbach

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Caroline J. Breitbach. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Caroline J. Breitbach. The network helps show where Caroline J. Breitbach may publish in the future.

Co-authorship network of co-authors of Caroline J. Breitbach

This figure shows the co-authorship network connecting the top 25 collaborators of Caroline J. Breitbach. A scholar is included among the top collaborators of Caroline J. Breitbach based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Caroline J. Breitbach. Caroline J. Breitbach is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Shearer, Todd, Mark C. Johnson, Ewa Cendrowicz, et al.. (2024). Kinetics of Nirogacestat-Mediated Increases in B-cell Maturation Antigen on Plasma Cells Inform Therapeutic Combinations in Multiple Myeloma. Cancer Research Communications. 4(12). 3114–3123.

Konstantinopoulos, Panagiotis A., et al.. (2023). Trial in progress: A phase two trial of nirogacestat, a gamma-secretase inhibitor, in patients with recurrent ovarian granulosa cell tumors (NCT05348356) (1284). Gynecologic Oncology. 176. S177–S178. 2 indexed citations

Breitbach, Caroline J.. (2019). Considerations for Clinical Translation of MG1 Maraba Virus. Methods in molecular biology. 2058. 285–293. 9 indexed citations

Pol, Jonathan, Matthew J. Atherton, Byram W. Bridle, et al.. (2018). Development and applications of oncolytic Maraba virus vaccines. PubMed. Volume 7. 117–128. 38 indexed citations

Kim, Minah, Maximilian Nitschké, Barbara Sennino, et al.. (2017). Amplification of Oncolytic Vaccinia Virus Widespread Tumor Cell Killing by Sunitinib through Multiple Mechanisms. Cancer Research. 78(4). 922–937. 55 indexed citations

Park, Se Hoon, Caroline J. Breitbach, Jeeyun Lee, et al.. (2015). Phase 1b Trial of Biweekly Intravenous Pexa-Vec (JX-594), an Oncolytic and Immunotherapeutic Vaccinia Virus in Colorectal Cancer. Molecular Therapy. 23(9). 1532–1540. 140 indexed citations

Breitbach, Caroline J., John C. Bell, Tae-Ho Hwang, David H. Kirn, & James M. Burke. (2015). The emerging therapeutic potential of the oncolytic immunotherapeutic Pexa-Vec (JX-594). PubMed. 4. 25–25. 46 indexed citations

Breitbach, Caroline J., Kelley A. Parato, James M. Burke, et al.. (2015). Pexa-Vec double agent engineered vaccinia: oncolytic and active immunotherapeutic. Current Opinion in Virology. 13. 49–54. 39 indexed citations

Breitbach, Caroline J., Anne Moon, James M. Burke, Tae-Ho Hwang, & David H. Kirn. (2015). A Phase 2, Open-Label, Randomized Study of Pexa-Vec (JX-594) Administered by Intratumoral Injection in Patients with Unresectable Primary Hepatocellular Carcinoma. Methods in molecular biology. 1317. 343–357. 73 indexed citations

10.

Lichty, Brian D., Caroline J. Breitbach, David F. Stojdl, & John C. Bell. (2014). Going viral with cancer immunotherapy. Nature reviews. Cancer. 14(8). 559–567. 481 indexed citations breakdown →

11.

Zeh, Herbert J., Stephanie Downs‐Canner, J. Andrea McCart, et al.. (2014). First-in-man Study of Western Reserve Strain Oncolytic Vaccinia Virus: Safety, Systemic Spread, and Antitumor Activity. Molecular Therapy. 23(1). 202–214. 120 indexed citations

12.

Breitbach, Caroline J., Rozanne Arulanandam, Naomi De Silva, et al.. (2013). Oncolytic Vaccinia Virus Disrupts Tumor-Associated Vasculature in Humans. Cancer Research. 73(4). 1265–1275. 208 indexed citations

13.

Tai, Lee‐Hwa, Christiano Tanese de Souza, Simon Bélanger, et al.. (2012). Preventing Postoperative Metastatic Disease by Inhibiting Surgery-Induced Dysfunction in Natural Killer Cells. Cancer Research. 73(1). 97–107. 187 indexed citations

14.

Breitbach, Caroline J., Steve H. Thorne, John C. Bell, & David H. Kirn. (2012). Targeted and Armed Oncolytic Poxviruses for Cancer: the Lead Example of JX-594. Current Pharmaceutical Biotechnology. 13(9). 1768–1772. 35 indexed citations

15.

Parato, Kelley A., Caroline J. Breitbach, Fabrice Le Bœuf, et al.. (2011). The Oncolytic Poxvirus JX-594 Selectively Replicates in and Destroys Cancer Cells Driven by Genetic Pathways Commonly Activated in Cancers. Molecular Therapy. 20(4). 749–758. 224 indexed citations

16.

Lun, Xueqing, Jennifer A. Chan, Hongyuan Zhou, et al.. (2010). Efficacy and Safety/Toxicity Study of Recombinant Vaccinia Virus JX-594 in Two Immunocompetent Animal Models of Glioma. Molecular Therapy. 18(11). 1927–1936. 77 indexed citations

17.

Alajez, Nehad M., Joseph D. Mocanu, Wei Shi, et al.. (2008). Efficacy of Systemically Administered Mutant Vesicular Stomatitis Virus (VSVΔ51) Combined with Radiation for Nasopharyngeal Carcinoma. Clinical Cancer Research. 14(15). 4891–4897. 18 indexed citations

18.

Stanford, Marianne M., Caroline J. Breitbach, John C. Bell, & Grant McFadden. (2008). Innate immunity, tumor microenvironment and oncolytic virus therapy: friends or foes?. PubMed. 10(1). 32–7. 37 indexed citations

19.

Colina, Rodney, Mauro Costa‐Mattioli, Ryan J.O. Dowling, et al.. (2008). Translational control of the innate immune response through IRF-7. Nature. 452(7185). 323–328. 260 indexed citations

20.

Burk, David L., Bing Xiong, Caroline J. Breitbach, & Albert M. Berghuis. (2005). Structures of aminoglycoside acetyltransferase AAC(6′)-Ii in a novel crystal form: structural and normal-mode analyses. Acta Crystallographica Section D Biological Crystallography. 61(9). 1273–1279. 21 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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