Can Gan

677 citations

17 papers · 423 indexed · 2 hit papers · h-index 10

Impact in

Hepatology top 5%
- Liver physiology and pathology
- Liver Disease and Transplantation
- Liver Diseases and Immunity
Epidemiology
- Liver Disease Diagnosis and Treatment

Papers in ⓘ

Hepatology 11
- Liver physiology and pathology 5
- Liver Disease and Transplantation 4
- Liver Diseases and Immunity 2
Epidemiology 8
- Liver Disease Diagnosis and Treatment 7

Co-authors: Jinhang Gao (10 shared papers)Chengwei Tang (7 shared papers)Yangkun Guo (2 shared papers)Enis Kostallari (3 shared papers)Yang Tai (3 shared papers)Bei Li (1 shared paper)Chong Zhao (1 shared paper)Tian Lan (2 shared papers)
Journals: JCI Insight (2 papers)Gastroenterology (2 papers)Journal of Hepatology (1 paper)Cell Reports (1 paper)Frontiers in Immunology (1 paper)
Partner nations: China United States Switzerland

In The Last Decade

Can Gan

17 papers receiving 416 citations

Hit Papers

align trajectories log scale

Liver diseases: epidemiology, causes, trends and predictions 2025 · 39 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2025 Signal Transduction and Targeted Therapy
2023 Redox Biology

Peers

Countries citing papers authored by Can Gan

Since Specialization

Citations

This map shows the geographic impact of Can Gan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Can Gan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Can Gan more than expected).

Fields of papers citing papers by Can Gan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Can Gan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Can Gan. The network helps show where Can Gan may publish in the future.

Co-authors

The 25 scholars most cited alongside Can Gan, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Can Gan Line = papers co-authored together Can Gan links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

17 of 17 papers shown

#	Work
1	STING mediates hepatocyte pyroptosis in liver fibrosis by Epigenetically activating the NLRP3 inflammasome Redox Biology ·Yang Xiao, Chong Zhao, Yang Tai, Bei Li, Tian Lan, Enjiang Lai, Wenting Dai, Yangkun Guo, Can Gan, Enis Kostallari, Chengwei Tang, Jinhang Gao Hit paper breakdown →	2023	104
2	Inflammasomes and Pyroptosis of Liver Cells in Liver Fibrosis Frontiers in Immunology ·Can Gan, Qiuyu Cai, Chengwei Tang, Jinhang Gao	2022	69
3	Mechanotransduction-induced glycolysis epigenetically regulates a CXCL1-dominant angiocrine signaling program in liver sinusoidal endothelial cells in vitro and in vivo Journal of Hepatology ·Thomas Greuter, Usman Yaqoob, Can Gan, Nidhi Jalan‐Sakrikar, Enis Kostallari, Jianwen Lu, Jinhang Gao, Liankang Sun, Mengfei Liu, Tejasav S. Sehrawat, Samar H. Ibrahim, Kunimaro Furuta, Katerina Nozickova, Bing Huang, Bin Gao, Michael Simons, Sheng Cao, Vijay H. Shah	2022	59
4	PD-L1 promotes myofibroblastic activation of hepatic stellate cells by distinct mechanisms selective for TGF-β receptor I versus II Cell Reports ·Liankang Sun, Yuanguo Wang, Xianghu Wang, Amaia Navarro‐Corcuera, Sumera I. Ilyas, Nidhi Jalan‐Sakrikar, Can Gan, Xinyi Tu, Yu Shi, Kangsheng Tu, Qingguang Liu, Zhenkun Lou, Haidong Dong, Arlene H. Sharpe, Vijay H. Shah, Ningling Kang	2022	42
5	Liver diseases: epidemiology, causes, trends and predictions Signal Transduction and Targeted Therapy ·Can Gan, Yuan Yuan, Haiyuan Shen, Jinhang Gao, Xiangxin Kong, Zhaodi Che, Yangkun Guo, Hua Wang, Erdan Dong, Jia Xiao Hit paper breakdown →	2025	39
6	Mechanism and Therapeutic Opportunities of Histone Modifications in Chronic Liver Disease Frontiers in Pharmacology ·Qiuyu Cai, Can Gan, Chengwei Tang, Hao Wu, Jinhang Gao	2021	21
7	Efficacy and safety of pancreatic enzyme replacement therapy on exocrine pancreatic insufficiency: a meta-analysis Oncotarget ·Can Gan, Yan-Hua Chen, Ling Liu, Jin-Hang Gao, Huan Tong, Cheng-Wei Tang, Rui Liu	2017	20
8	Celecoxib ameliorates liver cirrhosis via reducing inflammation and oxidative stress along spleen-liver axis in rats Life Sciences ·Shihang Tang, Zhiyin Huang, Jingsun Jiang, Jinhang Gao, Chong Zhao, Yang Tai, Xiao Ma, Linhao Zhang, Yanting Ye, Can Gan, Wei Su, Xintong Jia, Rui Liu, Hao Wu, Chengwei Tang	2021	16
9	High HIF-1α expression predicts poor prognosis of patients with colon adenocarcinoma. PubMed ·Zhiyin Huang, Linhao Zhang, Chong Zhao, Rui Liu, Huan Tong, Can Gan, Tian Lan, Chengwei Tang, Jinhang Gao	2018	13
10	Risk factors for overt hepatic encephalopathy after transjugular intrahepatic portosystemic shunt creation in patients with liver cirrhosis Journal of Digestive Diseases ·Huan Tong, Can Gan, Bo Wei, Zhi Dong Wang, Xiaodan Li, Shuai Jie Qian, Hui Huang, Lin Hao Zhang, Zhu Yang, Yi-Long Chen, Yong Hong Gu, Liu Xiang Chen, Yang Yu, Hao Wu, Cheng Wei Tang	2020	10
11	Liver sinusoidal endothelial cells contribute to portal hypertension through collagen type IV–driven sinusoidal remodeling JCI Insight ·Can Gan, Usman Yaqoob, Jianwen Lu, Man Xie, Abid Anwar, Nidhi Jalan‐Sakrikar, Sofía Jerez, Tejasav S. Sehrawat, Amaia Navarro‐Corcuera, Enis Kostallari, Nawras W. Habash, Sheng Cao, Vijay H. Shah	2024	7
12	High expression of long non-coding RNA Linc-A associates with poor survival in patients with colorectal cancer Molecular Biology Reports ·Chong Zhao, Can Gan, Xiao Yang, Rui Liu, Linhao Zhang, Tian Lan, Yanting Ye, Huan Tong, Zhiyin Huang, Chengwei Tang, Jinhang Gao	2020	7
13	Atypical cholangiocytes derived from hepatocyte-cholangiocyte transdifferentiation mediated by COX-2: a kind of misguided liver regeneration Inflammation and Regeneration ·Tian Lan, Yang Tai, Chong Zhao, Yang Xiao, Zhu Yang, Linhao Zhang, Can Gan, Wenting Dai, Huan Tong, Chengwei Tang, Zhiyin Huang, Jinhang Gao	2023	6
14	Telomere dysfunction promotes cholangiocyte senescence and biliary fibrosis in primary sclerosing cholangitis JCI Insight ·Nidhi Jalan‐Sakrikar, Abid Anwar, Usman Yaqoob, Can Gan, Anthony B. Lagnado, Alexander Q. Wixom, Diana Jurk, Robert C. Huebert	2023	4
15	MASLD development: From molecular pathogenesis toward therapeutic strategies Chinese Medical Journal ·Zhu Yang, Jiahui Zhao, Kexin Xie, Chengwei Tang, Can Gan, Jinhang Gao	2025	4
16	601 – The Effect of Esomeprazole on the Duodenal Microbiota in Severe Acute Pancreatitis: A Prospective Randomized Controlled Stud Gastroenterology ·Xiao Ma, Zhiyin Huang, Shihang Tang, Can Gan, Xintong Jia, Yanting Ye, Ling Liu, Chengwei Tang	2019	1
17	Mo2029 – Octreotide Ameliorates Obesity-Induced Pancreatic Steatosis Via Srebp-1C Pathway Gastroenterology ·Can Gan, Chengwei Tang, Rui Liu	2019	1

About Can Gan

Can Gan is a scholar working on Hepatology, Epidemiology, Surgery, Molecular Biology and Oncology, having authored 17 papers that have together received 423 indexed citations. Recurring topics across this work include Liver Disease Diagnosis and Treatment (7 papers), Liver physiology and pathology (5 papers), Liver Disease and Transplantation (4 papers), Pancreatitis Pathology and Treatment (2 papers), Pancreatic and Hepatic Oncology Research (2 papers), Liver Diseases and Immunity (2 papers), Inflammasome and immune disorders (2 papers) and Organ Transplantation Techniques and Outcomes (2 papers). The work is most often cited by research in Hepatology (135 citations), Epidemiology (168 citations), Immunology (86 citations), Cancer Research (49 citations) and Pharmacology (24 citations). Can Gan has collaborated with scholars based in China, United States and Switzerland. Frequent co-authors include Jinhang Gao, Chengwei Tang, Yangkun Guo, Enis Kostallari, Yang Tai, Bei Li, Chong Zhao, Tian Lan, Yang Xiao and Nidhi Jalan‐Sakrikar. Their work appears in journals such as JCI Insight, Gastroenterology, Journal of Hepatology, Cell Reports and Frontiers in Immunology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact