Brian Spencer

645 total citations
24 papers, 432 citations indexed

About

Brian Spencer is a scholar working on Molecular Biology, Cell Biology and Physiology. According to data from OpenAlex, Brian Spencer has authored 24 papers receiving a total of 432 indexed citations (citations by other indexed papers that have themselves been cited), including 24 papers in Molecular Biology, 6 papers in Cell Biology and 6 papers in Physiology. Recurrent topics in Brian Spencer's work include Amyloidosis: Diagnosis, Treatment, Outcomes (24 papers), Protein Kinase Regulation and GTPase Signaling (7 papers) and Cellular transport and secretion (5 papers). Brian Spencer is often cited by papers focused on Amyloidosis: Diagnosis, Treatment, Outcomes (24 papers), Protein Kinase Regulation and GTPase Signaling (7 papers) and Cellular transport and secretion (5 papers). Brian Spencer collaborates with scholars based in United States, Italy and Türkiye. Brian Spencer's co-authors include Tatiana Prokaeva, Lawreen H. Connors, David C. Seldin, Martha Skinner, Gheorghe Doros, K. Bodi, Al Ozonoff, Giampaolo Merlini, Mark E. McComb and David H. Perlman and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Blood and Journal of the American College of Cardiology.

In The Last Decade

Brian Spencer

22 papers receiving 427 citations

Peers

Brian Spencer

PHYSI

ONCOL

NEPHR

Veronica Valentini Italy

Alan Solomon United States

D Wolfenbarger United States

S̆árka S̆ı́mová Czechia

Ghaleb H. Daouk United States

Jayde E. Ruelcke Australia

Tomáš Pika Czechia

Daniel R. Radiloff United States

Zhiyong Deng China

Veronica Valentini Italy

Brian Spencer

517 ×1.3

94 ×1.0

PHYSI

167 ×1.9

ONCOL

48 ×0.8

131 ×2.3

NEPHR

Citations per year, relative to Brian Spencer Brian Spencer (= 1×) peers Veronica Valentini

Countries citing papers authored by Brian Spencer

Since Specialization

Citations

This map shows the geographic impact of Brian Spencer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Brian Spencer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Brian Spencer more than expected).

Fields of papers citing papers by Brian Spencer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Brian Spencer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Brian Spencer. The network helps show where Brian Spencer may publish in the future.

Co-authorship network of co-authors of Brian Spencer

This figure shows the co-authorship network connecting the top 25 collaborators of Brian Spencer. A scholar is included among the top collaborators of Brian Spencer based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Brian Spencer. Brian Spencer is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Prokaeva, Tatiana, Brian Spencer, Shobini Jayaraman, et al.. (2025). Cryo-EM of Cardiac AL-224L Amyloid Reveals Shared Structural Motifs and Mutation-induced Differences in λ6 Light Chain Fibrils. Journal of Molecular Biology. 438(3). 169591–169591.

Prokaeva, Tatiana, Shobini Jayaraman, Elena S. Klimtchuk, et al.. (2025). An unusual phenotype of hereditary AApoAI amyloidosis caused by a novel Asp20Tyr substitution is linked to pH-dependent aggregation of apolipoprotein A-I. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1871(5). 167820–167820.

Morgan, Gareth J., et al.. (2024). Predicting Structural Consequences of Antibody Light Chain N-Glycosylation in AL Amyloidosis. Pharmaceuticals. 17(11). 1542–1542. 2 indexed citations

Klimtchuk, Elena S., Tatiana Prokaeva, Brian Spencer, et al.. (2024). Conformational Differences in the Light Chain Constant Domain of Immunoglobulin G and Free Light Chain May Influence Proteolysis in AL Amyloidosis. Journal of Molecular Biology. 436(23). 168837–168837. 3 indexed citations

Morgan, Gareth J., Allison Nau, Brian Spencer, et al.. (2024). An updated AL-base reveals ranked enrichment of immunoglobulin light chain variable genes in AL amyloidosis. Amyloid. 32(2). 129–138. 5 indexed citations

Helmke, Stephen, Carlos J. Rodríguez, Tatiana Prokaeva, et al.. (2024). DIFFERENTIAL ASSOCIATION OF TRANSTHYRETIN KINETIC STABILITY WITH VARIANT AND WILDTYPE TRANSTHYRETIN CARDIAC AMYLOIDOSIS: THE SCAN-MP STUDY. Journal of the American College of Cardiology. 83(13). 4603–4603. 1 indexed citations

Schmidt, Alexander, Ikram Ullah, Denise Fine, et al.. (2024). TRANSTHYRETIN AMYLOID CARDIOMYOPATHY IS ASSOCIATED WITH WORSE OUTCOMES WHEN COMPARED TO PATIENTS WITH NON-AMYLOID RELATED HEART FAILURE OF SIMILAR RACE AND ETHNICITY: THE SCAN-MP STUDY. Journal of the American College of Cardiology. 83(13). 520–520. 1 indexed citations

Lau, K. H. Vincent, Tatiana Prokaeva, Gheorghe Doros, et al.. (2023). Neurofilament light chain kinetics as a biomarker for polyneuropathy in V122I hereditary transthyretin amyloidosis. Amyloid. 31(2). 150–152. 4 indexed citations

Mendelson, Lisa, Tatiana Prokaeva, K. H. Vincent Lau, et al.. (2023). Hereditary gelsolin amyloidosis: a rare cause of cranial, peripheral and autonomic neuropathies linked to D187N and Y447H substitutions. Amyloid. 30(4). 357–363. 3 indexed citations

10.

Prokaeva, Tatiana, Elena S. Klimtchuk, Brian Spencer, et al.. (2022). An additive destabilising effect of compound T60I and V122I substitutions in ATTRv amyloidosis. Amyloid. 30(2). 141–152. 2 indexed citations

11.

Prokaeva, Tatiana, Elena S. Klimtchuk, Brian Spencer, et al.. (2022). A novel substitution of proline (P32L) destabilises β2-microglobulin inducing hereditary systemic amyloidosis. Amyloid. 29(4). 255–262. 6 indexed citations

12.

Klimtchuk, Elena S., Tatiana Prokaeva, Brian Spencer, et al.. (2018). Unusual duplication mutation in a surface loop of human transthyretin leads to an aggressive drug-resistant amyloid disease. Proceedings of the National Academy of Sciences. 115(28). E6428–E6436. 29 indexed citations

13.

Prokaeva, Tatiana, Harun Akar, Brian Spencer, et al.. (2017). Hereditary Renal Amyloidosis Associated With a Novel Apolipoprotein A-II Variant. Kidney International Reports. 2(6). 1223–1232. 20 indexed citations

14.

Klimtchuk, Elena S., Tatiana Prokaeva, Brian Spencer, Olga Gursky, & Lawreen H. Connors. (2017). In vitro co-expression of human amyloidogenic immunoglobulin light and heavy chain proteins: a relevant cell-based model of AL amyloidosis. Amyloid. 24(2). 115–122. 8 indexed citations

15.

Logue, Mark W., Gloria Chan, Brian Spencer, et al.. (2014). Genetic variation of the transthyretin gene in wild-type transthyretin amyloidosis (ATTRwt). Human Genetics. 134(1). 111–121. 17 indexed citations

16.

Girnius, Saulius, Martha Skinner, Brian Spencer, et al.. (2012). A new lysozyme tyr54asn mutation causing amyloidosis in a family of Swedish ancestry with gastrointestinal symptoms. Amyloid. 19(4). 182–185. 19 indexed citations

17.

Spencer, Brian, et al.. (2011). Dysregulation of miRNAs in AL amyloidosis. Amyloid. 18(3). 128–135. 7 indexed citations

18.

Bodi, K., et al.. (2009). AL-Base: a visual platform analysis tool for the study of amyloidogenic immunoglobulin light chain sequences. Amyloid. 16(1). 1–8. 80 indexed citations

19.

Lavatelli, Francesca, David H. Perlman, Brian Spencer, et al.. (2008). Amyloidogenic and Associated Proteins in Systemic Amyloidosis Proteome of Adipose Tissue. Molecular & Cellular Proteomics. 7(8). 1570–1583. 115 indexed citations

20.

Prokaeva, Tatiana, Brian Spencer, Al Ozonoff, et al.. (2007). Soft tissue, joint, and bone manifestations of AL amyloidosis: Clinical presentation, molecular features, and survival. Arthritis & Rheumatism. 56(11). 3858–3868. 97 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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