Brian M. McKeever

4.0k total citations · 1 hit paper
46 papers, 2.5k citations indexed

About

Brian M. McKeever is a scholar working on Molecular Biology, Organic Chemistry and Materials Chemistry. According to data from OpenAlex, Brian M. McKeever has authored 46 papers receiving a total of 2.5k indexed citations (citations by other indexed papers that have themselves been cited), including 24 papers in Molecular Biology, 15 papers in Organic Chemistry and 7 papers in Materials Chemistry. Recurrent topics in Brian M. McKeever's work include Enzyme Structure and Function (6 papers), Organophosphorus compounds synthesis (5 papers) and HIV/AIDS drug development and treatment (5 papers). Brian M. McKeever is often cited by papers focused on Enzyme Structure and Function (6 papers), Organophosphorus compounds synthesis (5 papers) and HIV/AIDS drug development and treatment (5 papers). Brian M. McKeever collaborates with scholars based in United States, Australia and Netherlands. Brian M. McKeever's co-authors include James P. Springer, Manuel A. Navia, Paula M.D. Fitzgerald, Jill C. Heimbach, Chih‐Tai Leu, Wayne K. Herber, Irving S. Sigal, Joseph W. Becker, H R Williams and Conrad P. Dorn and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Brian M. McKeever

43 papers receiving 2.4k citations

Hit Papers

Three-dimensional structure of aspartyl protease from hum... 1989 2026 2001 2013 1989 200 400 600
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1
    1989 700 citations Manuel A. Navia, Paula M.D. Fitzgerald et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Brian M. McKeever United States 24 1.4k 731 617 615 229 46 2.5k
Susan Erickson‐Viitanen United States 40 2.4k 1.7× 1.2k 1.7× 1.1k 1.8× 1.4k 2.3× 272 1.2× 81 5.1k
Kent D. Stewart United States 34 1.3k 0.9× 559 0.8× 322 0.5× 967 1.6× 333 1.5× 91 3.1k
Bertil Samuelsson Sweden 34 1.6k 1.2× 843 1.2× 295 0.5× 1.6k 2.7× 554 2.4× 134 3.6k
Paul L. Darke United States 34 1.4k 1.0× 1.3k 1.8× 1.1k 1.7× 756 1.2× 157 0.7× 63 2.8k
Kenichi Akaji Japan 32 2.2k 1.6× 506 0.7× 166 0.3× 1.3k 2.1× 389 1.7× 188 3.4k
Maxwell D. Cummings United States 26 1.6k 1.1× 681 0.9× 263 0.4× 577 0.9× 498 2.2× 52 2.9k
Michael J. Sofia United States 32 1.7k 1.2× 1.2k 1.6× 172 0.3× 1.1k 1.7× 194 0.8× 122 3.8k
Steven A. Short United States 41 2.7k 2.0× 868 1.2× 557 0.9× 470 0.8× 89 0.4× 79 4.0k
William G. Rice United States 39 3.1k 2.3× 1.2k 1.7× 1.1k 1.8× 972 1.6× 170 0.7× 108 5.4k
Silvio Massa Italy 39 1.8k 1.3× 1.2k 1.6× 692 1.1× 2.2k 3.6× 214 0.9× 171 4.3k

Countries citing papers authored by Brian M. McKeever

Since Specialization
Citations

This map shows the geographic impact of Brian M. McKeever's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Brian M. McKeever with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Brian M. McKeever more than expected).

Fields of papers citing papers by Brian M. McKeever

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Brian M. McKeever. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Brian M. McKeever. The network helps show where Brian M. McKeever may publish in the future.

Co-authorship network of co-authors of Brian M. McKeever

This figure shows the co-authorship network connecting the top 25 collaborators of Brian M. McKeever. A scholar is included among the top collaborators of Brian M. McKeever based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Brian M. McKeever. Brian M. McKeever is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Marcus, Andrew P., Ya‐Jun Zheng, Katerina Leftheris, et al.. (2016). Identification of spirooxindole and dibenzoxazepine motifs as potent mineralocorticoid receptor antagonists. Bioorganic & Medicinal Chemistry. 24(6). 1384–1391. 22 indexed citations
2.
Yuan, Jing, Shankar Venkatraman, Ya‐Jun Zheng, et al.. (2013). Structure-Based Design of β-Site APP Cleaving Enzyme 1 (BACE1) Inhibitors for the Treatment of Alzheimer’s Disease. Journal of Medicinal Chemistry. 56(11). 4156–4180. 111 indexed citations
3.
Bukhtiyarov, Yuri, et al.. (2012). Regulation of Sphingomyelin Phosphodiesterase Acid-Like 3A Gene (SMPDL3A) by Liver X Receptors. Molecular Pharmacology. 82(4). 719–727. 17 indexed citations
4.
Liu, Weiguo, Kun Liu, Harold B. Wood, et al.. (2011). Benzimidazolones: A New Class of Selective Peroxisome Proliferator-Activated Receptor γ (PPARγ) Modulators. Journal of Medicinal Chemistry. 54(24). 8541–8554. 48 indexed citations
5.
Einstein, Monica, Taro E. Akiyama, Gino Castriota, et al.. (2007). The Differential Interactions of Peroxisome Proliferator-Activated Receptor γ Ligands with Tyr473 Is a Physical Basis for Their Unique Biological Activities. Molecular Pharmacology. 73(1). 62–74. 63 indexed citations
6.
Xu, Shihua, Brian M. McKeever, Douglas Wisniewski, et al.. (2007). Expression, purification and crystallization of human 5-lipoxygenase-activating protein with leukotriene-biosynthesis inhibitors. Acta Crystallographica Section F Structural Biology and Crystallization Communications. 63(12). 1054–1057. 8 indexed citations
7.
Deng, Qiaolin, Zhijian Lu, Kenneth Ellsworth, et al.. (2005). Modeling aided design of potent glycogen phosphorylase inhibitors. Journal of Molecular Graphics and Modelling. 23(5). 457–464. 7 indexed citations
8.
Lu, Zhijian, Raynald Bergeron, Qiaolin Deng, et al.. (2003). A new class of glycogen phosphorylase inhibitors. Bioorganic & Medicinal Chemistry Letters. 13(22). 4125–4128. 28 indexed citations
9.
McKeever, Brian M., Wayne M. Geissler, Ling Wu, et al.. (2002). Amino acid substitution of arginine 80 in 17β-hydroxysteroid dehydrogenase type 3 and its effect on NADPH cofactor binding and oxidation/reduction kinetics. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1601(1). 29–37. 35 indexed citations
10.
Rotonda, J., Margarita García‐Calvo, Wayne M. Geissler, et al.. (2001). The three-dimensional structure of human granzyme B compared to caspase-3, key mediators of cell death with cleavage specificity for aspartic acid in P1. Chemistry & Biology. 8(4). 357–368. 67 indexed citations
11.
Chen, Shiying, Bruce A. Johnson, Ying Li, et al.. (2000). Both Coactivator LXXLL Motif-dependent and -independent Interactions Are Required for Peroxisome Proliferator-activated Receptor γ (PPARγ) Function. Journal of Biological Chemistry. 275(6). 3733–3736. 42 indexed citations
12.
Smith, Graham, Richard Alexander, Brian M. McKeever, et al.. (1994). Positions of His‐64 and a bound water in human carbonic anhydrase II upon binding three structurally related inhibitors. Protein Science. 3(1). 118–125. 52 indexed citations
13.
Becker, J.W., J. Rotonda, Brian M. McKeever, et al.. (1993). FK-506-binding protein: three-dimensional structure of the complex with the antagonist L-685,818. Journal of Biological Chemistry. 268(15). 11335–11339. 55 indexed citations
14.
Thompson, Wayne J., Paula M.D. Fitzgerald, M. Katharine Holloway, et al.. (1992). Synthesis and antiviral activity of a series of HIV-1 protease inhibitors with functionality tethered to the P1 or P1' phenyl design. Journal of Medicinal Chemistry. 35(10). 1685–1701. 137 indexed citations
15.
Prugh, John D., George D. Hartman, Pierre Mallorga, et al.. (1991). New isomeric classes of topically active ocular hypotensive carbonic anhydrase inhibitors: 5-substituted thieno[2,3-b]thiophene-2-sulfonamides and 5-substituted thieno[3,2-b]thiophene-2-sulfonamides. Journal of Medicinal Chemistry. 34(6). 1805–1818. 97 indexed citations
16.
Fitzgerald, Paula M.D., Brian M. McKeever, James P. Springer, et al.. (1990). Crystallographic analysis of a complex between human immunodeficiency virus type 1 protease and acetyl-pepstatin at 2.0-A resolution.. Journal of Biological Chemistry. 265(24). 14209–14219. 211 indexed citations
17.
Navia, Manuel A. & Brian M. McKeever. (1990). A Role for the Aspartyl Protease from the Human Immunodeficiency Virus Type 1 (HIV‐1) in the Orchestration of Virus Assembly. Annals of the New York Academy of Sciences. 616(1). 73–85. 26 indexed citations
18.
Navia, Manuel A., Paula M.D. Fitzgerald, Brian M. McKeever, et al.. (1989). Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1. Nature. 337(6208). 615–620. 700 indexed citations breakdown →
19.
McKeever, Brian M., Manuel A. Navia, Paula M.D. Fitzgerald, et al.. (1989). Crystallization of the aspartylprotease from the human immunodeficiency virus, HIV-1. Journal of Biological Chemistry. 264(4). 1919–1921. 30 indexed citations
20.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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