Brett D. Hollingshead

1.8k total citations · 1 hit paper
20 papers, 1.2k citations indexed

About

Brett D. Hollingshead is a scholar working on Molecular Biology, Immunology and Health, Toxicology and Mutagenesis. According to data from OpenAlex, Brett D. Hollingshead has authored 20 papers receiving a total of 1.2k indexed citations (citations by other indexed papers that have themselves been cited), including 8 papers in Molecular Biology, 6 papers in Immunology and 5 papers in Health, Toxicology and Mutagenesis. Recurrent topics in Brett D. Hollingshead's work include Carcinogens and Genotoxicity Assessment (5 papers), Toxic Organic Pollutants Impact (5 papers) and RNA Interference and Gene Delivery (3 papers). Brett D. Hollingshead is often cited by papers focused on Carcinogens and Genotoxicity Assessment (5 papers), Toxic Organic Pollutants Impact (5 papers) and RNA Interference and Gene Delivery (3 papers). Brett D. Hollingshead collaborates with scholars based in United States, Canada and France. Brett D. Hollingshead's co-authors include Gary H. Perdew, Timothy V. Beischlag, José L. Quiles, Preeti Ramadoss, John R. Petrulis, Ann Kusnadi, Brett C. DiNatale, Rushang D. Patel, Curtis J. Omiecinski and Andrew D. Burdick and has published in prestigious journals such as Nucleic Acids Research, Journal of Biological Chemistry and PLoS ONE.

In The Last Decade

Brett D. Hollingshead

19 papers receiving 1.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Aryl Hydrocarbon Receptor Complex and the Control of Gene Expression

2008 579 citations Timothy V. Beischlag, José L. Quiles et al. Critical Reviews in Eukaryotic Gene Expression profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Brett D. Hollingshead United States	11	519	419	247	154	124	20	1.2k
Jennifer Marlowe United States	13	486 0.9×	477 1.1×	326 1.3×	129 0.8×	87 0.7×	17	1.2k
Danica E. DeGroot United States	8	285 0.5×	444 1.1×	214 0.9×	126 0.8×	83 0.7×	9	947
Ellen C. Henry United States	21	387 0.7×	677 1.6×	391 1.6×	175 1.1×	112 0.9×	31	1.3k
Togo Ikuta Japan	20	913 1.8×	403 1.0×	352 1.4×	246 1.6×	222 1.8×	31	1.7k
Willy A. Solis United States	10	437 0.8×	500 1.2×	281 1.1×	65 0.4×	139 1.1×	14	1.1k
Markus R. Probst United States	17	637 1.2×	652 1.6×	524 2.1×	108 0.7×	147 1.2×	20	1.6k
Nadine Dragin France	22	394 0.8×	324 0.8×	263 1.1×	273 1.8×	280 2.3×	32	1.6k
Shigeyuki Uno Japan	24	678 1.3×	451 1.1×	484 2.0×	127 0.8×	384 3.1×	43	1.8k
Rushang D. Patel United States	12	282 0.5×	146 0.3×	108 0.4×	89 0.6×	82 0.7×	37	763
William K. Chan United States	15	718 1.4×	138 0.3×	319 1.3×	73 0.5×	180 1.5×	37	1.4k

Countries citing papers authored by Brett D. Hollingshead

Since Specialization

Citations

This map shows the geographic impact of Brett D. Hollingshead's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Brett D. Hollingshead with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Brett D. Hollingshead more than expected).

Fields of papers citing papers by Brett D. Hollingshead

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Brett D. Hollingshead. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Brett D. Hollingshead. The network helps show where Brett D. Hollingshead may publish in the future.

Co-authorship network of co-authors of Brett D. Hollingshead

This figure shows the co-authorship network connecting the top 25 collaborators of Brett D. Hollingshead. A scholar is included among the top collaborators of Brett D. Hollingshead based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Brett D. Hollingshead. Brett D. Hollingshead is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Hollingshead, Brett D. & Zaher A. Radi. (2025). Human Relevance of Pharmaceutical Drug‐Induced Thyroid Tumors in Rats, Labeling Implications, and Carcinogenicity Study Requirements. Journal of Applied Toxicology. 45(8). 1426–1439.

Rana, Payal, Brett D. Hollingshead, & Raja S. Mangipudy. (2024). Rethinking the necessity of long-term toxicity studies for biotherapeutics using weight of evidence assessment. Regulatory Toxicology and Pharmacology. 153. 105710–105710. 2 indexed citations

Bodenlenz, Manfred, Gabriel Berstein, Jaymin Shah, et al.. (2023). Comparative Study of Dermal Pharmacokinetics Between Topical Drugs Using Open Flow Microperfusion in a Pig Model. Pharmaceutical Research. 41(2). 223–234. 5 indexed citations

Hollingshead, Brett D., Nasir Khan, Maik Schuler, & Zaher A. Radi. (2022). Development challenges for carcinogenicity risk assessments of topical drugs. The Journal of Toxicological Sciences. 47(1). 1–11. 2 indexed citations

Hollingshead, Brett D., Lindsay Tomlinson, Stacey R. Oppenheimer, et al.. (2021). An orthogonal methods assessment of topical drug concentrations in skin and the impact for risk assessment in the viable epidermis. Regulatory Toxicology and Pharmacology. 123. 104934–104934. 3 indexed citations

Schuler, Maik, Lindsay Tomlinson, Yutian Zhan, et al.. (2021). Experiments in the EpiDerm 3D Skin In Vitro Model and Minipigs In Vivo Indicate Comparatively Lower In Vivo Skin Sensitivity of Topically Applied Aneugenic Compounds. Toxicological Sciences. 180(1). 103–121. 5 indexed citations

Gerstenberger, Brian S., Mary Ellen Banker, James D. Clark, et al.. (2020). Demonstration of In Vitro to In Vivo Translation of a TYK2 Inhibitor That Shows Cross Species Potency Differences. Scientific Reports. 10(1). 8974–8974. 7 indexed citations

LaBranche, Timothy P., Anna K. Kopec, Srinivasa R. Mantena, et al.. (2020). Zucker Lean Rats With Hepatic Steatosis Recapitulate Asymptomatic Metabolic Syndrome and Exhibit Greater Sensitivity to Drug-Induced Liver Injury Compared With Standard Nonclinical Sprague-Dawley Rat Model. Toxicologic Pathology. 48(8). 994–1007. 2 indexed citations

Burdick, Andrew D., Simone Sciabola, Srinivasa R. Mantena, et al.. (2014). Sequence motifs associated with hepatotoxicity of locked nucleic acid—modified antisense oligonucleotides. Nucleic Acids Research. 42(8). 4882–4891. 114 indexed citations

10.

Kakiuchi-Kiyota, Satoko, Petra Koza‐Taylor, Srinivasa R. Mantena, et al.. (2013). Comparison of Hepatic Transcription Profiles of Locked Ribonucleic Acid Antisense Oligonucleotides: Evidence of Distinct Pathways Contributing to Non-target Mediated Toxicity in Mice. Toxicological Sciences. 138(1). 234–248. 41 indexed citations

11.

Hollingshead, Brett D., et al.. (2013). High‐Throughput Gene Silencing and mRNA Expression Analysis in Hepatocyte Sandwich Cultures. Current Protocols in Toxicology. 55(1). Unit 14.11–Unit 14.11. 2 indexed citations

12.

Labrecque, Mark P., Mandeep Takhar, Brett D. Hollingshead, et al.. (2012). Distinct Roles for Aryl Hydrocarbon Receptor Nuclear Translocator and Ah Receptor in Estrogen-Mediated Signaling in Human Cancer Cell Lines. PLoS ONE. 7(1). e29545–e29545. 39 indexed citations

13.

Perdew, Gary H., Brett D. Hollingshead, Brett C. DiNatale, et al.. (2010). Estrogen Receptor Expression Is Required for Low-Dose Resveratrol-Mediated Repression of Aryl Hydrocarbon Receptor Activity. Journal of Pharmacology and Experimental Therapeutics. 335(2). 273–283. 31 indexed citations

14.

Hollingshead, Brett D., Timothy V. Beischlag, Brett C. DiNatale, Preeti Ramadoss, & Gary H. Perdew. (2008). Inflammatory Signaling and Aryl Hydrocarbon Receptor Mediate Synergistic Induction of Interleukin 6 in MCF-7 Cells. Cancer Research. 68(10). 3609–3617. 107 indexed citations

15.

Beischlag, Timothy V., José L. Quiles, Brett D. Hollingshead, & Gary H. Perdew. (2008). The Aryl Hydrocarbon Receptor Complex and the Control of Gene Expression. Critical Reviews in Eukaryotic Gene Expression. 18(3). 207–250. 579 indexed citations breakdown →

16.

Patel, Rushang D., Brett D. Hollingshead, Curtis J. Omiecinski, & Gary H. Perdew. (2007). Aryl-hydrocarbon receptor activation regulates constitutive androstane receptor levels in murine and human liver. Hepatology. 46(1). 209–218. 62 indexed citations

17.

Hollingshead, Brett D., Rushang D. Patel, & Gary H. Perdew. (2006). Endogenous Hepatic Expression of the Hepatitis B Virus X-Associated Protein 2 Is Adequate for Maximal Association with Aryl Hydrocarbon Receptor-90-kDa Heat Shock Protein Complexes. Molecular Pharmacology. 70(6). 2096–2107. 18 indexed citations

18.

Hollingshead, Brett D., John R. Petrulis, & Gary H. Perdew. (2004). The Aryl Hydrocarbon (Ah) Receptor Transcriptional Regulator Hepatitis B Virus X-associated Protein 2 Antagonizes p23 Binding to Ah Receptor-Hsp90 Complexes and Is Dispensable for Receptor Function. Journal of Biological Chemistry. 279(44). 45652–45661. 40 indexed citations

19.

Petrulis, John R., Ann Kusnadi, Preeti Ramadoss, Brett D. Hollingshead, & Gary H. Perdew. (2003). The hsp90 Co-chaperone XAP2 Alters Importin β Recognition of the Bipartite Nuclear Localization Signal of the Ah Receptor and Represses Transcriptional Activity. Journal of Biological Chemistry. 278(4). 2677–2685. 89 indexed citations

20.

Ramadoss, Preeti, John R. Petrulis, Brett D. Hollingshead, Ann Kusnadi, & Gary H. Perdew. (2003). Divergent Roles of Hepatitis B Virus X-Associated Protein 2 (XAP2) in Human versus Mouse Ah Receptor Complexes. Biochemistry. 43(3). 700–709. 39 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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