Brad E. Hoffman

2.4k total citations
35 papers, 2.0k citations indexed

About

Brad E. Hoffman is a scholar working on Genetics, Molecular Biology and Oncology. According to data from OpenAlex, Brad E. Hoffman has authored 35 papers receiving a total of 2.0k indexed citations (citations by other indexed papers that have themselves been cited), including 21 papers in Genetics, 16 papers in Molecular Biology and 16 papers in Oncology. Recurrent topics in Brad E. Hoffman's work include Virus-based gene therapy research (21 papers), CAR-T cell therapy research (15 papers) and CRISPR and Genetic Engineering (8 papers). Brad E. Hoffman is often cited by papers focused on Virus-based gene therapy research (21 papers), CAR-T cell therapy research (15 papers) and CRISPR and Genetic Engineering (8 papers). Brad E. Hoffman collaborates with scholars based in United States, China and Australia. Brad E. Hoffman's co-authors include Roland W. Herzog, David M. Markusic, Cox Terhorst, Sushrusha Nayak, Geoffrey D. Keeler, Emilia L. Oleszak, Ou Cao, Michael Barnett, Eun‐Sook Cho and Eunice E. Kwon and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Blood and The Journal of Immunology.

In The Last Decade

Brad E. Hoffman

34 papers receiving 1.9k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Brad E. Hoffman United States 25 972 965 552 368 256 35 2.0k
Nanette Mittereder United States 10 669 0.7× 905 0.9× 323 0.6× 437 1.2× 62 0.2× 11 1.6k
Ute Modlich Germany 28 2.1k 2.1× 2.8k 2.9× 1.1k 1.9× 454 1.2× 45 0.2× 78 3.7k
Claudia R. Ball Germany 17 695 0.7× 1.2k 1.2× 736 1.3× 231 0.6× 79 0.3× 43 1.8k
Ali Nowrouzi Germany 19 999 1.0× 1.5k 1.5× 550 1.0× 183 0.5× 26 0.1× 28 2.0k
John T. Gray United States 28 1.7k 1.8× 2.1k 2.2× 682 1.2× 189 0.5× 26 0.1× 55 2.8k
Cory Allen United States 20 941 1.0× 933 1.0× 491 0.9× 234 0.6× 81 0.3× 29 1.9k
Peter Yaciuk United States 21 852 0.9× 1.7k 1.7× 872 1.6× 299 0.8× 165 0.6× 31 2.4k
D. Hewett Australia 23 696 0.7× 915 0.9× 369 0.7× 644 1.8× 142 0.6× 41 2.5k
Christian Beltinger Germany 22 388 0.4× 1.3k 1.3× 449 0.8× 303 0.8× 75 0.3× 57 2.0k
David‐Alexandre Gross France 23 529 0.5× 898 0.9× 458 0.8× 911 2.5× 35 0.1× 41 1.7k

Countries citing papers authored by Brad E. Hoffman

Since Specialization
Citations

This map shows the geographic impact of Brad E. Hoffman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Brad E. Hoffman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Brad E. Hoffman more than expected).

Fields of papers citing papers by Brad E. Hoffman

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Brad E. Hoffman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Brad E. Hoffman. The network helps show where Brad E. Hoffman may publish in the future.

Co-authorship network of co-authors of Brad E. Hoffman

This figure shows the co-authorship network connecting the top 25 collaborators of Brad E. Hoffman. A scholar is included among the top collaborators of Brad E. Hoffman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Brad E. Hoffman. Brad E. Hoffman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Keeler, Geoffrey D., et al.. (2022). Induction of antigen-specific tolerance by hepatic AAV immunotherapy regardless of T cell epitope usage or mouse strain background. Molecular Therapy — Methods & Clinical Development. 28. 177–189. 8 indexed citations
2.
Yin, Ling, Geoffrey D. Keeler, Brad E. Hoffman, et al.. (2020). AAV3-miRNA vectors for growth suppression of human hepatocellular carcinoma cells in vitro and human liver tumors in a murine xenograft model in vivo. Gene Therapy. 28(7-8). 422–434. 24 indexed citations
3.
Yang, Hua, Keyun Qing, Geoffrey D. Keeler, et al.. (2020). Enhanced Transduction of Human Hematopoietic Stem Cells by AAV6 Vectors: Implications in Gene Therapy and Genome Editing. Molecular Therapy — Nucleic Acids. 20. 451–458. 19 indexed citations
4.
Rogers, Geoffrey L., Jamie L. Shirley, Irene Zolotukhin, et al.. (2017). Plasmacytoid and conventional dendritic cells cooperate in crosspriming AAV capsid-specific CD8+ T cells. Blood. 129(24). 3184–3195. 96 indexed citations
5.
Herzog, Roland W., Mario Cooper, George Q. Perrin, et al.. (2017). Regulatory T cells and TLR9 activation shape antibody formation to a secreted transgene product in AAV muscle gene transfer. Cellular Immunology. 342. 103682–103682. 33 indexed citations
6.
Krotova, Karina, George Marek, George Aslanidi, et al.. (2017). Alpha-1 Antitrypsin-Deficient Macrophages Have Increased Matriptase-Mediated Proteolytic Activity. American Journal of Respiratory Cell and Molecular Biology. 57(2). 238–247. 16 indexed citations
7.
Keeler, Geoffrey D., David M. Markusic, & Brad E. Hoffman. (2017). Liver induced transgene tolerance with AAV vectors. Cellular Immunology. 342. 103728–103728. 57 indexed citations
8.
Kumar, Sandeep, Brad E. Hoffman, Cox Terhorst, Ype P. de Jong, & Roland W. Herzog. (2017). The Balance between CD8+ T Cell-Mediated Clearance of AAV-Encoded Antigen in the Liver and Tolerance Is Dependent on the Vector Dose. Molecular Therapy. 25(4). 880–891. 61 indexed citations
9.
Keeler, Geoffrey D., et al.. (2017). Gene Therapy-Induced Antigen-Specific Tregs Inhibit Neuro-inflammation and Reverse Disease in a Mouse Model of Multiple Sclerosis. Molecular Therapy. 26(1). 173–183. 73 indexed citations
10.
Zolotukhin, Irene, et al.. (2016). Potential for cellular stress response to hepatic factor VIII expression from AAV vector. Molecular Therapy — Methods & Clinical Development. 3. 16063–16063. 57 indexed citations
11.
Vercauteren, Koen, Brad E. Hoffman, Irene Zolotukhin, et al.. (2016). Superior In vivo Transduction of Human Hepatocytes Using Engineered AAV3 Capsid. Molecular Therapy. 24(6). 1042–1049. 93 indexed citations
12.
Xiao, Yuhong, et al.. (2015). Low cost delivery of proteins bioencapsulated in plant cells to human non-immune or immune modulatory cells. Biomaterials. 80. 68–79. 42 indexed citations
13.
Sarkar, Debalina, Moanaro Biswas, Gongxian Liao, et al.. (2014). Ex vivo expanded autologous polyclonal regulatory T cells suppress inhibitor formation in hemophilia. Molecular Therapy — Methods & Clinical Development. 1. 14030–14030. 58 indexed citations
14.
Markusic, David M., Brad E. Hoffman, George Q. Perrin, et al.. (2013). Effective gene therapy for haemophilic mice with pathogenic factor IX antibodies. EMBO Molecular Medicine. 5(11). 1698–1709. 101 indexed citations
15.
Markusic, David M., Roland W. Herzog, George Aslanidi, et al.. (2010). High-efficiency Transduction and Correction of Murine Hemophilia B Using AAV2 Vectors Devoid of Multiple Surface-exposed Tyrosines. Molecular Therapy. 18(12). 2048–2056. 111 indexed citations
16.
Cao, Ou, Brad E. Hoffman, Babak Moghimi, et al.. (2009). Impact of the Underlying Mutation and the Route of Vector Administration on Immune Responses to Factor IX in Gene Therapy for Hemophilia B. Molecular Therapy. 17(10). 1733–1742. 84 indexed citations
17.
Cooper, Mario, Sushrusha Nayak, Brad E. Hoffman, et al.. (2009). Improved Induction of Immune Tolerance to Factor IX by Hepatic AAV-8 Gene Transfer. Human Gene Therapy. 20(7). 767–776. 78 indexed citations
18.
Nayak, Sushrusha, et al.. (2009). Prophylactic immune tolerance induced by changing the ratio of antigen‐specific effector to regulatory T cells. Journal of Thrombosis and Haemostasis. 7(9). 1523–1532. 60 indexed citations
19.
Oleszak, Emilia L., Brad E. Hoffman, J. Robert Chang, et al.. (2003). Apoptosis of infiltrating T cells in the central nervous system of mice infected with Theiler's murine encephalomyelitis virus. Virology. 315(1). 110–123. 17 indexed citations
20.
Prineas, John W., Eunice E. Kwon, Eun‐Sook Cho, et al.. (2001). Immunopathology of secondary‐progressive multiple sclerosis. Annals of Neurology. 50(5). 646–657. 315 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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