Bill J. Smith

2.6k citations

28 papers · 1.6k indexed · h-index 20

Oncology top 5%
Molecular Biology
Pharmacology top 1%
Pediatrics, Perinatology and Child Health top 5%
Cellular and Molecular Neuroscience top 10%

Co-authors: Cuiping Chen Xingrong Liu Donald R. Mattison I.G. Sipes John P. Gibbs Meihua Tu Natilie Hosea Thomas E. Eling
Topics: Drug Transport and Resistance Mechanisms (13 papers)Pharmacogenetics and Drug Metabolism (8 papers)Pharmacological Effects and Toxicity Studies (6 papers)
Cited by: Pharmacology Oncology Neurology
Journals: Journal of Pharmacology and Experimental Therapeutics Clinical Chemistry Journal of Pharmaceutical Sciences
Partner nations: United States United Kingdom Japan

In The Last Decade

Bill J. Smith

28 papers receiving 1.5k citations

Peers

Countries citing papers authored by Bill J. Smith

Since Specialization

Citations

This map shows the geographic impact of Bill J. Smith's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Bill J. Smith with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Bill J. Smith more than expected).

Fields of papers citing papers by Bill J. Smith

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Bill J. Smith. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Bill J. Smith. The network helps show where Bill J. Smith may publish in the future.

Co-authorship network of co-authors of Bill J. Smith

This figure shows the co-authorship network connecting the top 25 collaborators of Bill J. Smith. A scholar is included among the top collaborators of Bill J. Smith based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Bill J. Smith. Bill J. Smith is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Transporter Gene Regulation in Sandwich Cultured Human Hepatocytes Through the Activation of Constitutive Androstane Receptor (CAR) or Aryl Hydrocarbon Receptor (AhR) 2021 ·Frontiers in Pharmacology ·Congrong Niu,Bill J. Smith,Yurong Lai	9
2	In Vitro Hepatic Uptake in Human and Monkey Hepatocytes in the Presence and Absence of Serum Protein and Its In Vitro to In Vivo Extrapolation 2020 ·Drug Metabolism and Disposition ·Xiaomin Liang,Yeojin Park,(unknown),Hao Jia,(unknown),Congrong Niu,Kelly Wang,Bill J. Smith,Yurong Lai	17
3	Organic Anion-Transporting Polypeptide Genes Are Not Induced by the Pregnane X Receptor Activator Rifampin: Studies in Hepatocytes In Vitro and in Monkeys In Vivo 2019 ·Drug Metabolism and Disposition ·Congrong Niu,Yujin Wang,(unknown),(unknown),Eisuke Murakami,Raju Subramanian,Bill J. Smith,Yurong Lai	22
4	Prediction of Drug-Drug Interactions with Crizotinib as the CYP3A Substrate Using a Physiologically Based Pharmacokinetic Model 2015 ·Drug Metabolism and Disposition ·Shinji Yamazaki,Theodore R. Johnson,Bill J. Smith	41
5	Pharmacokinetics, Metabolism, and Excretion of [14C]Axitinib, a Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor, in Humans 2014 ·Drug Metabolism and Disposition ·Bill J. Smith,Yazdi K. Pithavala,Hai‐Zhi Bu,Ping Kang,Brian Hee,Alan Deese,William F. Pool,Karen J. Klamerus,Xinglin Wu,Deepak Dalvie	31
6	Metabolism, excretion and pharmacokinetics of [¹⁴C]crizotinib following oral administration to healthy subjects 2014 ·Xenobiotica ·Theodore R. Johnson,Weiwei Tan,Lance Goulet,Evan B. Smith,Shinji Yamazaki,Gregory S. Walker,Melissa O’Gorman,Gabriella Bedarida,Helen Y. Zou,James G. Christensen,Leslie Nguyen,Zhongzhou Shen,Deepak Dalvie,Akintunde Bello,Bill J. Smith	45
7	Application of Target-Mediated Drug Disposition Model to Small Molecule Heat Shock Protein 90 Inhibitors 2013 ·Drug Metabolism and Disposition ·Shinji Yamazaki,Zhongzhou Shen,Ying Jiang,Bill J. Smith,Paolo Vicini	20
8	Expression and Functional Analysis of Hepatic Cytochromes P450, Nuclear Receptors, and Membrane Transporters in 10- and 25-Week-Old db/db Mice 2010 ·Drug Metabolism and Disposition ·Justine L. Lam,Ying Jiang,Tao Zhang,Eric Y. Zhang,Bill J. Smith	36
9	Comparative gene expression profiles of ABC transporters in brain microvessel endothelial cells and brain in five species including human 2009 ·Pharmacological Research ·Mark S. Warren,Noa Zerangue,(unknown),Lori M. Roberts,Emily Tate,Bo Feng,Cheryl Li,Thomas J. Feuerstein,John P. Gibbs,Bill J. Smith	191
10	Progress in Brain Penetration Evaluation in Drug Discovery and Development 2008 ·Journal of Pharmacology and Experimental Therapeutics ·Xingrong Liu,Cuiping Chen,Bill J. Smith	129
11	Evaluation of Cerebrospinal Fluid Concentration and Plasma Free Concentration As a Surrogate Measurement for Brain Free Concentration 2006 ·Drug Metabolism and Disposition ·Xingrong Liu,Bill J. Smith,Cuiping Chen,Ernesto Callegari,Stacey L. Becker,Xi Chen,Julie Cianfrogna,Angela C. Doran,Shawn D. Doran,John P. Gibbs,Natilie Hosea,Jianhua Liu,Frederick Nelson,(unknown),(unknown)	129
12	Use of a Physiologically Based Pharmacokinetic Model to Study the Time to Reach Brain Equilibrium: An Experimental Analysis of the Role of Blood-Brain Barrier Permeability, Plasma Protein Binding, and Brain Tissue Binding 2005 ·Journal of Pharmacology and Experimental Therapeutics ·Xingrong Liu,Bill J. Smith,Cuiping Chen,Ernesto Callegari,Stacey L. Becker,Xi Chen,Julie Cianfrogna,Angela C. Doran,Shawn D. Doran,John P. Gibbs,Natilie Hosea,Jianhua Liu,Frederick Nelson,(unknown),(unknown)	136
13	DEVELOPMENT OF A COMPUTATIONAL APPROACH TO PREDICT BLOOD-BRAIN BARRIER PERMEABILITY 2004 ·Drug Metabolism and Disposition ·Xingrong Liu,Meihua Tu,(unknown),Cuiping Chen,Bill J. Smith	180
14	Utility of Mdr1-Gene Deficient Mice in Assessing the Impact of P-glycoprotein on Pharmacokinetics and Pharmacodynamics in Drug Discovery and Development 2003 ·Current Drug Metabolism ·Cuiping Chen,Xingrong Liu,Bill J. Smith	67
15	CHARACTERIZATION OF THE EFFECTS OF TEBUFELONE ON HEPATIC CYTOCHROMES P450 IN THE BEAGLE DOG 1996 ·Drug Metabolism and Disposition ·Bill J. Smith,(unknown),(unknown),R. W. Diters,(unknown),John N. Norton	7
16	Mutagenic activation of benzidine requires prior bacterial acetylation and subsequent conversion by prostaglandin H synthase to 4-nitro-4'-(acetylamino)biphenyl 1992 ·Chemical Research in Toxicology ·Bill J. Smith,Lillian S. DeBruin,P. David Josephy,Thomas E. Eling	35
17	Bioactivation of xenobiotics by prostaglandin H synthase 1991 ·Chemico-Biological Interactions ·Bill J. Smith,John F. Curtis,Thomas E. Eling	61
18	Hepatic Bioactivation of 4-Vinylcyclohexene to Ovotoxic Epoxides 1991 ·Advances in experimental medicine and biology ·Bill J. Smith,Donald R. Mattison,I.G. Sipes	3
19	Comparison of random and serial sections in assessment of ovarian toxicity 1991 ·Reproductive Toxicology ·Bill J. Smith,David R. Plowchalk,I.G. Sipes,Donald R. Mattison	48
20	The role of epoxidation in 4-vinylcyclohexene-induced ovarian toxicity 1990 ·Toxicology and Applied Pharmacology ·Bill J. Smith,Donald R. Mattison,I.G. Sipes	90

About Bill J. Smith

Bill J. Smith is a scholar working on Pharmacology, Oncology and Computational Theory and Mathematics, having authored 28 papers that have together received 1.6k indexed citations. Recurring topics across this work include Drug Transport and Resistance Mechanisms (13 papers), Pharmacogenetics and Drug Metabolism (8 papers) and Pharmacological Effects and Toxicity Studies (6 papers). The work is most often cited by research in Pharmacology (348 citations), Oncology (697 citations) and Neurology (157 citations). Bill J. Smith has collaborated with scholars based in United States, United Kingdom and Japan. Frequent co-authors include Cuiping Chen, Xingrong Liu, Xingrong Liu, Donald R. Mattison, I.G. Sipes, John P. Gibbs, Meihua Tu, Natilie Hosea, Thomas E. Eling and Angela C. Doran. Their work appears in journals such as Journal of Pharmacology and Experimental Therapeutics, Clinical Chemistry and Journal of Pharmaceutical Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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