Basil P. Hubbard

7.4k total citations · 3 hit papers
40 papers, 4.1k citations indexed

About

Basil P. Hubbard is a scholar working on Molecular Biology, Geriatrics and Gerontology and Oncology. According to data from OpenAlex, Basil P. Hubbard has authored 40 papers receiving a total of 4.1k indexed citations (citations by other indexed papers that have themselves been cited), including 19 papers in Molecular Biology, 18 papers in Geriatrics and Gerontology and 9 papers in Oncology. Recurrent topics in Basil P. Hubbard's work include Sirtuins and Resveratrol in Medicine (18 papers), Autophagy in Disease and Therapy (8 papers) and CRISPR and Genetic Engineering (8 papers). Basil P. Hubbard is often cited by papers focused on Sirtuins and Resveratrol in Medicine (18 papers), Autophagy in Disease and Therapy (8 papers) and CRISPR and Genetic Engineering (8 papers). Basil P. Hubbard collaborates with scholars based in Canada, United States and Australia. Basil P. Hubbard's co-authors include David Sinclair, Khushwant S. Bhullar, Amitabh Jha, H.P. Vasantha Rupasinghe, Indu Parmar, Eileen McGowan, Ana P. Gomes, Carlos M. Palmeira, Anabela P. Rolo and João S. Teodoro and has published in prestigious journals such as Science, Cell and Journal of Biological Chemistry.

In The Last Decade

Basil P. Hubbard

39 papers receiving 4.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging

2013 1.1k citations Ana P. Gomes, Nathan L. Price et al. Cell profile →
Kinase-targeted cancer therapies: progress, challenges and future directions

2018 883 citations Khushwant S. Bhullar, Basil P. Hubbard et al. profile →
Small molecule SIRT1 activators for the treatment of aging and age-related diseases

2014 456 citations Basil P. Hubbard, David Sinclair Trends in Pharmacological Sciences profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Basil P. Hubbard Canada	19	2.0k	1.2k	924	608	602	40	4.1k
Yong Pan United States	32	2.6k 1.3×	504 0.4×	679 0.7×	847 1.4×	496 0.8×	66	4.5k
Nükhet Aykin‐Burns United States	31	3.0k 1.5×	733 0.6×	1.5k 1.6×	567 0.9×	632 1.0×	72	5.7k
Pablo J. Fernández-Marcos Spain	23	2.3k 1.2×	866 0.7×	1.7k 1.8×	575 0.9×	719 1.2×	40	4.5k
Wei Yu China	30	3.1k 1.5×	1.9k 1.6×	1.5k 1.7×	606 1.0×	1.1k 1.9×	98	6.1k
Sean M. Armour United States	14	2.1k 1.1×	692 0.6×	910 1.0×	268 0.4×	521 0.9×	18	4.2k
Ja‐Eun Kim South Korea	33	3.0k 1.5×	750 0.6×	450 0.5×	752 1.2×	512 0.9×	81	4.4k
Lydia W.S. Finley United States	37	4.4k 2.2×	1.3k 1.0×	1.3k 1.4×	763 1.3×	1.0k 1.7×	48	6.9k
Andrei V. Budanov United States	26	4.5k 2.3×	377 0.3×	570 0.6×	930 1.5×	1.1k 1.9×	42	6.1k
Mahesh P. Gupta United States	43	4.0k 2.0×	2.7k 2.2×	1.8k 1.9×	852 1.4×	1.5k 2.5×	119	7.6k
Jihye Paik United States	30	3.0k 1.5×	273 0.2×	559 0.6×	354 0.6×	623 1.0×	56	4.4k

Countries citing papers authored by Basil P. Hubbard

Since Specialization

Citations

This map shows the geographic impact of Basil P. Hubbard's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Basil P. Hubbard with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Basil P. Hubbard more than expected).

Fields of papers citing papers by Basil P. Hubbard

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Basil P. Hubbard. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Basil P. Hubbard. The network helps show where Basil P. Hubbard may publish in the future.

Co-authorship network of co-authors of Basil P. Hubbard

This figure shows the co-authorship network connecting the top 25 collaborators of Basil P. Hubbard. A scholar is included among the top collaborators of Basil P. Hubbard based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Basil P. Hubbard. Basil P. Hubbard is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Wang, Ke, Jingan Chen, Shannon J. Tsai, et al.. (2025). A Reverse Transcription Nucleic-Acid-Based Barcoding System for In Vivo Measurement of Lipid Nanoparticle mRNA Delivery. PubMed. 5(1). 35–41. 1 indexed citations

Hubbard, Basil P., et al.. (2025). CRISPR/Cas technologies for cancer drug discovery and treatment. Trends in Pharmacological Sciences. 46(5). 437–452. 3 indexed citations

Beauchamp, Erwan, Christopher R. Cromwell, Morris A. Kostiuk, et al.. (2024). Multiomics analysis identifies oxidative phosphorylation as a cancer vulnerability arising from myristoylation inhibition. Journal of Translational Medicine. 22(1). 431–431. 7 indexed citations

Berthiaume, Luc G., Erwan Beauchamp, Morris A. Kostiuk, et al.. (2024). Abstract CT194: N-myristoylation inhibitor zelenirstat: New mechanistic insights and efficacy signals from a first in human phase I study. Cancer Research. 84(7_Supplement). CT194–CT194. 1 indexed citations

Beauchamp, Erwan, Aishwarya Iyer, Megan C. Yap, et al.. (2023). Abstract 1662: Understanding the sensitivity of cancer cells to myristoylation inhibitors for oncology applications. Cancer Research. 83(7_Supplement). 1662–1662. 1 indexed citations

Tang, Xiaoyun, Christopher R. Cromwell, Rong‐Zong Liu, et al.. (2022). Lipid phosphate phosphatase-2 promotes tumor growth through increased c-Myc expression. Theranostics. 12(13). 5675–5690. 11 indexed citations

Cromwell, Christopher R., et al.. (2022). Guide RNAs containing universal bases enable Cas9/Cas12a recognition of polymorphic sequences. Nature Communications. 13(1). 1617–1617. 37 indexed citations

Ali, Mohammad, Javier A. Garcia‐Vilas, Christopher R. Cromwell, et al.. (2021). Matrix metalloproteinase‐2 mediates ribosomal RNA transcription by cleaving nucleolar histones. FEBS Journal. 288(23). 6736–6751. 17 indexed citations

Cromwell, Christopher R. & Basil P. Hubbard. (2020). In Vitro Assays for Comparing the Specificity of First- and Next-Generation CRISPR/Cas9 Systems. Methods in molecular biology. 2162. 215–232. 5 indexed citations

10.

Julien, Olivier, et al.. (2020). A conserved acetylation switch enables pharmacological control of tubby-like protein stability. Journal of Biological Chemistry. 296. 100073–100073. 7 indexed citations

11.

Li, Jun, Michael S. Bonkowski, S. Moniot, et al.. (2017). A conserved NAD ⁺ binding pocket that regulates protein-protein interactions during aging. Science. 355(6331). 1312–1317. 126 indexed citations

12.

Dai, Han, James L. Ellis, David Sinclair, & Basil P. Hubbard. (2016). Synthesis and Assay of SIRT1-Activating Compounds. Methods in enzymology on CD-ROM/Methods in enzymology. 574. 213–244. 7 indexed citations

13.

Meter, Michael Van, Matthew Simon, Gregory Tombline, et al.. (2016). JNK Phosphorylates SIRT6 to Stimulate DNA Double-Strand Break Repair in Response to Oxidative Stress by Recruiting PARP1 to DNA Breaks. Cell Reports. 16(10). 2641–2650. 102 indexed citations

14.

Bhullar, Khushwant S. & Basil P. Hubbard. (2015). Lifespan and healthspan extension by resveratrol. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1852(6). 1209–1218. 212 indexed citations

15.

Hubbard, Basil P., Hang Dai, April Case, et al.. (2013). Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators. Science. 339(6124). 1216–1219. 20 indexed citations

16.

Hubbard, Basil P., Christine Loh, Ana P. Gomes, et al.. (2013). Carboxamide SIRT1 inhibitors block DBC1 binding via an acetylation-independent mechanism. Cell Cycle. 12(14). 2233–2240. 18 indexed citations

17.

Gomes, Ana P., Nathan L. Price, Javid J. Moslehi, et al.. (2013). Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging. Cell. 155(7). 1624–1638. 1108 indexed citations breakdown →

18.

Gomes, Ana P., Filipe V. Duarte, Patrícia M. Nunes, et al.. (2011). Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1822(2). 185–195. 126 indexed citations

19.

Yang, Yongjie, Basil P. Hubbard, David Sinclair, & Qiang Tong. (2010). Characterization of murine SIRT3 transcript variants and corresponding protein products. Journal of Cellular Biochemistry. 111(4). 1051–1058. 31 indexed citations

20.

Dai, Han, David P. Carney, April Case, et al.. (2010). SIRT1 Activation by Small Molecules. Journal of Biological Chemistry. 285(43). 32695–32703. 175 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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