Atsushi Akahane

688 citations

21 papers · 576 indexed · h-index 13

Co-authors: Takao Terai Y Shiokawa Steven P. Butcher Kahei Takase Keith Finlayson Henry J. Olverman Takayoshi Kinoshita Yasuhiro Kita
Topics: Adenosine and Purinergic Signaling (13 papers)Synthesis and Biological Evaluation (9 papers)Pharmacological Receptor Mechanisms and Effects (6 papers)
Cited by: Physiology Organic Chemistry Cellular and Molecular Neuroscience
Journals: Journal of Medicinal Chemistry Journal of Pharmacology and Experimental Therapeutics The Journal of Organic Chemistry
Partner nations: Japan United States United Kingdom

In The Last Decade

Atsushi Akahane

21 papers receiving 560 citations

Peers

Countries citing papers authored by Atsushi Akahane

Since Specialization

Citations

This map shows the geographic impact of Atsushi Akahane's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Atsushi Akahane with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Atsushi Akahane more than expected).

Fields of papers citing papers by Atsushi Akahane

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Atsushi Akahane. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Atsushi Akahane. The network helps show where Atsushi Akahane may publish in the future.

Co-authorship network of co-authors of Atsushi Akahane

This figure shows the co-authorship network connecting the top 25 collaborators of Atsushi Akahane. A scholar is included among the top collaborators of Atsushi Akahane based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Atsushi Akahane. Atsushi Akahane is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Pharmacological Characterization of a Novel, Potent Adenosine A1 and A2A Receptor Dual Antagonist, 5-[5-Amino-3-(4-fluorophenyl)pyrazin-2-yl]-1-isopropylpyridine-2(1 H)-one (ASP5854), in Models of Parkinson’s Disease and Cognition 2007 ·Journal of Pharmacology and Experimental Therapeutics ·Takuma Mihara,Kayoko Mihara,Junko Yarimizu,Yasuyuki Mitani,(unknown),Hiroko Yamamoto,(unknown),Atsushi Akahane,Akinori Iwashita,Nobuya Matsuoka	67
2	Pharmacological Characterization of FR194921, a New Potent, Selective, and Orally Active Antagonist for Central Adenosine A1 Receptors 2004 ·Journal of Pharmacological Sciences ·(unknown),(unknown),Takuma Mihara,(unknown),(unknown),Katsuya Harada,Takayuki Yamaji,(unknown),(unknown),Atsushi Akahane,Akinori Iwashita,Nobuya Matsuoka,Seitaro Mutoh	64
3	Design, Synthesis and Biological Evaluation of a Novel Series of Potent, Orally Active Adenosine A<SUB>1</SUB> Receptor Antagonists with High Blood-Brain Barrier Permeability 2001 ·Chemical and Pharmaceutical Bulletin ·(unknown),(unknown),Yoshiyuki Tenda,(unknown),(unknown),Atsushi Akahane,Kazuo Sakane	21
4	Novel adenosine A1 receptor antagonists. Synthesis and structure–activity relationships of a novel series of 3-(2-cyclohexenyl-3-oxo-2,3-dihydropyridazin-6-yl)-2-phenylpyrazolo[1,5-a]pyridines 2000 ·Bioorganic & Medicinal Chemistry ·(unknown),Atsushi Akahane,(unknown),Shintaro Nishimura,(unknown),Yoshiyuki Tenda,Kazuo Sakane	19
5	Discovery of FR166124, a novel water-soluble pyrazolo-[1,5-α]pyridine adenosine A1 receptor antagonist 1999 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),Atsushi Akahane,(unknown),Shintaro Nishimura,(unknown),Takayoshi Kinoshita,Yoshiyuki Tenda,Kazuo Sakane	39
6	Discovery of 6-Oxo-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-1(6H)-pyridazinebutanoic Acid (FK 838): A Novel Non-Xanthine Adenosine A₁Receptor Antagonist with Potent Diuretic Activity 1999 ·Journal of Medicinal Chemistry ·Atsushi Akahane,(unknown),(unknown),Takeshi Kato,Takayoshi Kinoshita,Yasuhiro Kita,(unknown),Takao Terai,Keizo Yoshida,Y Shiokawa	90
7	Synthesis of the water-soluble adenosine A1 receptor antagonist FR166124 through a novel sequential Horner-Emmons / isomerization reaction 1999 ·Tetrahedron ·(unknown),Atsushi Akahane,(unknown),Shintaro Nishimura,(unknown),Takayoshi Kinoshita,Isao Nakanishi,Kazuo Sakane	8
8	Pharmacological Characterization of a Simple Behavioral Response Mediated Selectively by Central Adenosine A1 Receptors, Using In Vivo and In Vitro Techniques 1998 ·Journal of Pharmacology and Experimental Therapeutics ·Hugh Marston,Keith Finlayson,(unknown),Henry J. Olverman,Atsushi Akahane,John Sharkey,Steven P. Butcher	53
9	Species differences in brain adenosine A₁ receptor pharmacology revealed by use of xanthine and pyrazolopyridine based antagonists 1997 ·British Journal of Pharmacology ·(unknown),Keith Finlayson,Henry J. Olverman,Atsushi Akahane,Roger W. Horton,Steven P. Butcher	51
10	A reinvestigation of the reported synthesis of the spirobenzyl isoquinoline alkaloid, iso-ochotensine 1997 ·Tetrahedron Letters ·A. I. MEYERS,Atsushi Akahane,(unknown),Joseph S. Warmus,Michael A. Gonzalez,(unknown)	3
11	Discovery of FK453, a novel non-xanthine adenosine A1 receptor antagonist 1996 ·Bioorganic & Medicinal Chemistry Letters ·Atsushi Akahane,(unknown),(unknown),Yasuhiro Kita,(unknown),Takao Terai,Keizo Yoshida,Y Shiokawa	21
12	General pharmacology of the new non-xanthine adenosine A1 receptor antagonist (+)-(R)-[(E)-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)acryloyl]-2- piperidine ethanol. 1996 ·PubMed ·Takao Terai,(unknown),Yuichi Kita,K. Yoshida,Atsushi Akahane,Y Shiokawa,Yoshiumi Kohno,(unknown),(unknown),Y Mine,MASANOBU KOHSAKA	3
13	A novel non-xanthine adenosine A1 receptor antagonist 1995 ·European Journal of Pharmacology ·Takao Terai,Yasuhiro Kita,(unknown),(unknown),Tsuyoshi Ando,(unknown),Atsushi Akahane,Y Shiokawa,K. Yoshida	22
14	Renal effects of FK453: A potent non‐xanthine adenosine A₁ receptor antagonist 1995 ·Drug Development Research ·Takao Terai,Yasuhiro Kita,(unknown),Takeshi F. Andoh,(unknown),(unknown),Atsushi Akahane,Y Shiokawa,Keizo Yoshida	8
15	Chiral formamidines. Asymmetric synthesis of 1,1-disubstituted tetrahydroisoquinolines. 1991 ·Tetrahedron Letters ·A. I. MEYERS,Michael A. Gonzalez,(unknown),Atsushi Akahane,Joseph W. Guiles,Joseph S. Warmus	30
16	Chiral formamidines. The mechanism of mono- and di-alkylation leading to chiral, non-racemic tetrahydroisoquinolines. 1991 ·Tetrahedron Letters ·A. I. MEYERS,Joseph S. Warmus,Michael A. Gonzalez,Joseph W. Guiles,Atsushi Akahane	10
17	The renal effects of FR-113453, a potent non-xanthine adenosine antagonist 1990 ·European Journal of Pharmacology ·Takao Terai,Yuichi Kita,(unknown),Tsuyoshi Ando,(unknown),Yoshiharu Deguchi,Atsushi Akahane,Y Shiokawa,K. Yoshida	10
18	Syntheses of arborescin, 1,10-epiarborescin, and (11S)-guaia-3,10(14)-dieno-13,6.alpha.-lactone, the key intermediate in Greene and Crabbe's estafiatin synthesis, and the stereochemical assignment of arborescin 1982 ·The Journal of Organic Chemistry ·Masayoshi Ando,Atsushi Akahane,(unknown),Kahei Takase	32
19	Studies on the Syntheses of Sesquiterpene Lactones. I. Chemical Transformation of α-Santonin into Vulgarin, C4-Epivulgarin, and Arglanine 1978 ·Bulletin of the Chemical Society of Japan ·Masayoshi Ando,Atsushi Akahane,Kahei Takase	13
20	STUDIES ON THE SYNTHESES OF SESQUITERPENE LACTONES V. TOTAL SYNTHESIS OF ARBORESCIN 1978 ·Chemistry Letters ·Masayoshi Ando,Atsushi Akahane,Kahei Takase	10

About Atsushi Akahane

Atsushi Akahane is a scholar working on Physiology, Organic Chemistry and Toxicology, having authored 21 papers that have together received 576 indexed citations. Recurring topics across this work include Adenosine and Purinergic Signaling (13 papers), Synthesis and Biological Evaluation (9 papers) and Pharmacological Receptor Mechanisms and Effects (6 papers). The work is most often cited by research in Physiology (271 citations), Organic Chemistry (291 citations) and Cellular and Molecular Neuroscience (102 citations). Atsushi Akahane has collaborated with scholars based in Japan, United States and United Kingdom. Frequent co-authors include Takao Terai, Y Shiokawa, Steven P. Butcher, Kahei Takase, Keith Finlayson, Henry J. Olverman, Takayoshi Kinoshita, Yasuhiro Kita, Keizo Yoshida and Akinori Iwashita. Their work appears in journals such as Journal of Medicinal Chemistry, Journal of Pharmacology and Experimental Therapeutics and The Journal of Organic Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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