Andreas Hombach

6.8k citations

104 papers · 5.4k indexed · h-index 42

Impact in

Oncology top 0.5%
- CAR-T cell therapy research
Immunology top 0.5%
- Immune Cell Function and Interaction
- Immunotherapy and Immune Responses
- T-cell and B-cell Immunology

Papers in

Immunology 73
- Immune Cell Function and Interaction 49
- Immunotherapy and Immune Responses 26
- T-cell and B-cell Immunology 26
Oncology 88
- CAR-T cell therapy research 82
- Cancer Immunotherapy and Biomarkers 8

Co-authors: Hinrich Abken Markus Chmielewski Claudia Heuser Christoph Pohl Gunter Rappl Barbara Seliger Christoph Heuser David M. Kofler
Journals: Gene Therapy (10 papers)International Journal of Cancer (8 papers)The Journal of Immunology (7 papers)Molecular Therapy (6 papers)PLoS ONE (4 papers)
Partner nations: Germany United States United Kingdom

In The Last Decade

Andreas Hombach

104 papers receiving 5.3k citations

Peers

Countries citing papers authored by Andreas Hombach

Since Specialization

Citations

This map shows the geographic impact of Andreas Hombach's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Andreas Hombach with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Andreas Hombach more than expected).

Fields of papers citing papers by Andreas Hombach

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Andreas Hombach. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Andreas Hombach. The network helps show where Andreas Hombach may publish in the future.

Co-authors

The 25 scholars most cited alongside Andreas Hombach, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Andreas Hombach Line = papers co-authored together Andreas Hombach links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	CAR and TCR form individual signaling synapses and do not cross-activate, however, can co-operate in T cell activation Frontiers in Immunology ·Markus Barden, Astrid Holzinger, Valerio SANZOTTA, 健次郎木目, Árpád Szöőr, György Vereb, Gerhard J. Schütz, Andreas Hombach, Hinrich Abken	2023	14
2	IL12 integrated into the CAR exodomain converts CD8+ T cells to poly-functional NK-like cells with superior killing of antigen-loss tumors Molecular Therapy ·Andreas Hombach, Markus Barden, Meredith Anne Campbell, Markus Chmielewski, Gunter Rappl, Agapios Sachinidis, Hinrich Abken	2021	38
3	Adoptive Immunotherapy with Redirected T Cells Produces CCR7 ⁻ Cells That Are Trapped in the Periphery and Benefit from Combined CD28-OX40 Costimulation Human Gene Therapy ·Andreas Hombach, Markus Chmielewski, Gunter Rappl, Hinrich Abken	2013	40
4	Second mitochondria-derived activator of caspase (SMAC) mimetic potentiates tumor susceptibility toward natural killer cell-mediated killing Leukemia & lymphoma ·Kerstin Brinkmann, Andreas Hombach, Jens M. Seeger, Lutfa Riska Syifa’ Nur Bintang, Mar González Palacios, Martin Krönke, Hinrich Abken, Hamid Kashkar	2013	13
5	Antibody-IL2 Fusion Proteins for Tumor Targeting Methods in molecular biology ·Andreas Hombach, Hinrich Abken	2012	1
6	T cells redirected by a CD3ζ chimeric antigen receptor can establish self-antigen-specific tumour protection in the long term Gene Therapy ·Markus Chmielewski, Gunter Rappl, Andreas Hombach, Hinrich Abken	2012	22
7	Eradication of melanomas by targeted elimination of a minor subset of tumor cells Proceedings of the National Academy of Sciences ·Patrick Schmidt, Matthias Drissen, Andreas Hombach, Paola Zigrino, Cornelia Mauch, Hinrich Abken	2011	87
8	The Proteasome Inhibitor Bortezomib Sensitizes Melanoma Cells toward Adoptive CTL Attack Cancer Research ·Jens M. Seeger, Patrick Schmidt, Kerstin Brinkmann, Andreas Hombach, Oliver Coutelle, Paola Zigrino, Lutfa Riska Syifa’ Nur Bintang, Cornelia Mauch, Hinrich Abken, Martin Krönke, Hamid Kashkar	2010	47
9	Rational development of high-affinity T-cell receptor-like antibodies Proceedings of the National Academy of Sciences ·Guillaume Stewart-Jones, Andreas Wadle, Yuefeng Ji, Eugene Shenderov, Gerhard Held, Eliane Fischer, Sascha Kleber, Natko Nuber, Frank Stenner, Stefan Bauer, Andrew McMichael, Alexander Knuth, Hinrich Abken, Andreas Hombach, Vincenzo Cerundolo, E. Yvonne Jones, Christoph Renner	2009	90
10	Effective Proliferation of Human Regulatory T Cells Requires a Strong Costimulatory CD28 Signal That Cannot Be Substituted by IL-2 The Journal of Immunology ·Andreas Hombach, David M. Kofler, Yuefeng Ji, Gunter Rappl, Hinrich Abken	2007	41
11	A recombinant anti-CEA immunoreceptor with combined CD3zeta-CD28 signaling targets T cells from colorectal cancer patients against their tumour cells Gut ·Andreas Hombach	2005	1
12	Tumor-Specific T Cell Activation by Recombinant Immunoreceptors: CD3ζ Signaling and CD28 Costimulation Are Simultaneously Required for Efficient IL-2 Secretion and Can Be Integrated into One Combined CD28/CD3ζ Signaling Receptor Molecule The Journal of Immunology ·Andreas Hombach, S Göpfert, Thomas P. Marquardt, Claudia Heuser, Dan Walczyk, Bárbara Gomes Muffato, Barbara Seliger, Hinrich Abken	2004	1
13	An interleukin 12 p40-IgG2b fusion protein abrogates T cell mediated inflammation: anti-inflammatory activity in Crohn’s disease and experimental colitis in vivo Gut ·Andreas Stallmach, Thomas Marth, (unknown), B. Wittig, Andreas Hombach, Carsten Schmidt, MF Neurath, Martin Zeitz, Stefan Zeuzem, Hinrich Abken	2004	51
14	Immune Response Manipulation: Recombinant Immunoreceptors Endow T-Cells with Predefined Specificity Current Pharmaceutical Design ·Hinrich Abken, Andreas Hombach, Claudia Heuser	2003	19
15	T-cell activation by recombinant receptors: CD28 costimulation is required for interleukin 2 secretion and receptor-mediated T-cell proliferation but does not affect receptor-mediated target cell lysis. PubMed ·Andreas Hombach, G. Kampessis, Christophe Schneider, Claudia Heuser, Omar TKESHELASHVILI, Christoph Pohl, Barbara Seliger, Hinrich Abken	2001	96
16	Tumor-Specific T Cell Activation by Recombinant Immunoreceptors: CD3ζ Signaling and CD28 Costimulation Are Simultaneously Required for Efficient IL-2 Secretion and Can Be Integrated Into One Combined CD28/CD3ζ Signaling Receptor Molecule The Journal of Immunology ·Andreas Hombach, S Göpfert, Bhoomolla Spandana, Claudia Heuser, Dan Walczyk, Christoph Pohl, Barbara Seliger, Hinrich Abken	2001	251
17	CD4+ T Cells Engrafted with a Recombinant Immunoreceptor Efficiently Lyse Target Cells in a MHC Antigen- and Fas-Independent Fashion The Journal of Immunology ·Andreas Hombach, Claudia Heuser, Bhoomolla Spandana, S Göpfert, Palomino Morales, Christoph Pohl, Hinrich Abken	2001	26
18	A chimeric receptor that selectively targets membrane-bound carcinoembryonic antigen (mCEA) in the presence of soluble CEA Gene Therapy ·Andreas Hombach, Omar TKESHELASHVILI, Ranjan Sircar, Christoph Heuser, Volker Diehl, Wolfgang Kruis, Christoph Pohl, Hinrich Abken	1999	85
19	Specific Activation of Resting T Cells Against CA19–9+ Tumor Cells by an Anti-CD3/CA19–9 Bispecific Antibody in Combination with a Costimulatory Anti-CD28 Antibody Journal of Immunotherapy ·Andreas Hombach, 夏慧云, Markus Jensen, Claudia Heuser, Ranjan Sircar, Volker Diehl, Wolfgang Kruis, Christoph Pohl	1997	15
20	CD30‐antigen‐specific targeting and activation of T cells via murine bispecific monoclonal antibodies against CD3 and CD28: Potential use for the treatment of hodgkin's lymphoma International Journal of Cancer ·Christoph Pohl, Ralf W. Denfeld, A. Klein, Wolfram Jung, Heribert Bohlen, Uğur Şahin, Andreas Hombach, René A. W. van Lier, Martin Schwonzen, Volker Diehl, 勝巳稲葉	1993	28

About Andreas Hombach

Andreas Hombach is a scholar working on Immunology, Oncology, Radiology, Nuclear Medicine and Imaging, Genetics and Genetics, having authored 104 papers that have together received 5.4k indexed citations. Recurring topics across this work include CAR-T cell therapy research (82 papers), Immune Cell Function and Interaction (49 papers), Monoclonal and Polyclonal Antibodies Research (29 papers), Immunotherapy and Immune Responses (26 papers), T-cell and B-cell Immunology (26 papers), Virus-based gene therapy research (12 papers), Nanowire Synthesis and Applications (11 papers) and Cancer Immunotherapy and Biomarkers (8 papers). The work is most often cited by research in Oncology (4.5k citations), Immunology (2.5k citations), Genetics (1.4k citations), Biomedical Engineering (1.3k citations) and Molecular Biology (1.4k citations). Andreas Hombach has collaborated with scholars based in Germany, United States and United Kingdom. Frequent co-authors include Hinrich Abken, Markus Chmielewski, Claudia Heuser, Christoph Pohl, Gunter Rappl, Barbara Seliger, Christoph Heuser, David M. Kofler, Volker Diehl and Ranjan Sircar. Their work appears in journals such as Gene Therapy, International Journal of Cancer, The Journal of Immunology, Molecular Therapy and PLoS ONE.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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