Andreas Fregin

2.4k total citations · 1 hit paper
17 papers, 1.8k citations indexed

About

Andreas Fregin is a scholar working on Nutrition and Dietetics, Molecular Biology and Pharmacology. According to data from OpenAlex, Andreas Fregin has authored 17 papers receiving a total of 1.8k indexed citations (citations by other indexed papers that have themselves been cited), including 10 papers in Nutrition and Dietetics, 7 papers in Molecular Biology and 6 papers in Pharmacology. Recurrent topics in Andreas Fregin's work include Vitamin K Research Studies (10 papers), Pharmacogenetics and Drug Metabolism (6 papers) and Blood Coagulation and Thrombosis Mechanisms (4 papers). Andreas Fregin is often cited by papers focused on Vitamin K Research Studies (10 papers), Pharmacogenetics and Drug Metabolism (6 papers) and Blood Coagulation and Thrombosis Mechanisms (4 papers). Andreas Fregin collaborates with scholars based in Germany, United Kingdom and Slovakia. Andreas Fregin's co-authors include Johannes Oldenburg, Clemens R. Müller, Simone Rost, Hans‐Joachim Pelz, Vytautas Ivaškevičius, Knut Tore Lappegård, Edward G. D. Tuddenham, Konstanze Hörtnagel, Tim M. Strom and E. Seifried and has published in prestigious journals such as Nature, Blood and Genetics.

In The Last Decade

Andreas Fregin

17 papers receiving 1.7k citations

Hit Papers

Mutations in VKORC1 cause warfarin resistance and multipl... 2004 2026 2011 2018 2004 250 500 750
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2
    2004 857 citations Simone Rost, Andreas Fregin et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Andreas Fregin Germany 14 861 519 461 392 259 17 1.8k
Vytautas Ivaškevičius Germany 16 552 0.6× 237 0.5× 278 0.6× 269 0.7× 102 0.4× 41 1.5k
Da-Yun Jin United States 13 468 0.5× 449 0.9× 318 0.7× 230 0.6× 45 0.2× 15 1.0k
Rebecca B. Raftogianis United States 14 655 0.8× 88 0.2× 230 0.5× 1.0k 2.7× 23 0.1× 19 2.1k
Shohei Matsuzaki Japan 17 166 0.2× 60 0.1× 286 0.6× 352 0.9× 26 0.1× 61 1.7k
Peter J. Dolphin Canada 30 61 0.1× 249 0.5× 1.0k 2.2× 974 2.5× 24 0.1× 79 2.7k
Carine Beysen United States 22 29 0.0× 255 0.5× 644 1.4× 586 1.5× 22 0.1× 35 2.0k
Chengtao Her United States 23 519 0.6× 30 0.1× 229 0.5× 1.4k 3.6× 37 0.1× 47 2.2k
Rachel Hertz Israel 27 95 0.1× 133 0.3× 194 0.4× 1.7k 4.4× 13 0.1× 56 2.3k
Thomas H. Zytkovicz United States 11 62 0.1× 224 0.4× 57 0.1× 604 1.5× 11 0.0× 19 1.2k
R. Dargel Germany 17 196 0.2× 129 0.2× 130 0.3× 315 0.8× 10 0.0× 80 1.2k

Countries citing papers authored by Andreas Fregin

Since Specialization
Citations

This map shows the geographic impact of Andreas Fregin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Andreas Fregin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Andreas Fregin more than expected).

Fields of papers citing papers by Andreas Fregin

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Andreas Fregin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Andreas Fregin. The network helps show where Andreas Fregin may publish in the future.

Co-authorship network of co-authors of Andreas Fregin

This figure shows the co-authorship network connecting the top 25 collaborators of Andreas Fregin. A scholar is included among the top collaborators of Andreas Fregin based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Andreas Fregin. Andreas Fregin is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

17 of 17 papers shown
1.
Fregin, Andreas, et al.. (2017). Building a Computer Vision Research Vehicle with ROS. 2 indexed citations
2.
Müller, Elisabeth, Alexander Keller, Andreas Fregin, Clemens R. Müller, & Simone Rost. (2014). Confirmation of warfarin resistance of naturally occurring VKORC1 variants by coexpression with coagulation factor IX and in silico protein modelling. BMC Genetics. 15(1). 17–17. 13 indexed citations
3.
Fregin, Andreas, Simone Rost, Myriam Taverna, et al.. (2013). A new cell culture-based assay quantifies vitamin K 2,3-epoxide reductase complex subunit 1 function and reveals warfarin resistance phenotypes not shown by the dithiothreitol-driven VKOR assay. Journal of Thrombosis and Haemostasis. 11(5). 872–880. 29 indexed citations
4.
Bevans, Carville G., Andreas Fregin, Christof Geisen, et al.. (2007). Current pharmacogenetic developments in oral anticoagulation therapy: The influence of variant VKORC1 and CYP2C9 alleles. Thrombosis and Haemostasis. 98(9). 570–578. 60 indexed citations
5.
Rost, Simone, Christof Geisen, Andreas Fregin, et al.. (2006). Founder mutation Arg485Pro led to recurrent compound heterozygous GGCX genotypes in two German patients with VKCFD type 1. Blood Coagulation & Fibrinolysis. 17(6). 503–507. 17 indexed citations
6.
Rost, Simone, et al.. (2005). Site-directed mutagenesis of coumarin-type anticoagulant-sensitive VKORC1. Thrombosis and Haemostasis. 94(10). 780–786. 79 indexed citations
7.
Pelz, Hans‐Joachim, Simone Rost, Andreas Fregin, et al.. (2005). The Genetic Basis of Resistance to Anticoagulants in Rodents. Genetics. 170(4). 1839–1847. 242 indexed citations
8.
Rost, Simone, et al.. (2004). Compound heterozygous mutations in the γ‐glutamyl carboxylase gene cause combined deficiency of all vitamin K‐dependent blood coagulation factors. British Journal of Haematology. 126(4). 546–549. 64 indexed citations
9.
Rost, Simone, Andreas Fregin, Vytautas Ivaškevičius, et al.. (2004). Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2. Nature. 427(6974). 537–541. 857 indexed citations breakdown →
10.
Oldenburg, Johannes, Simone Rost, Andreas Fregin, et al.. (2004). Mutations in the VKORC1 Gene Cause Warfarin Resistance, Warfarin Sensitivity and Combined Deficiency of Vitamin K Dependent Coagulation Factors.. Blood. 104(11). 277–277. 1 indexed citations
11.
Müller, Clemens R., et al.. (2002). Alkaptonuria in Slovakia: thirty-two years of research on phenotype and genotype. Molecular Genetics and Metabolism. 75(4). 353–359. 27 indexed citations
12.
Fregin, Andreas, Simone Rost, Werner Wolz, et al.. (2002). Homozygosity mapping of a second gene locus for hereditary combined deficiency of vitamin K–dependent clotting factors to the centromeric region of chromosome 16. Blood. 100(9). 3229–3232. 57 indexed citations
13.
Oldenburg, Johannes, Vytautas Ivaškevičius, Simone Rost, et al.. (2001). Evaluation of DHPLC in the analysis of hemophilia A. Journal of Biochemical and Biophysical Methods. 47(1-2). 39–51. 66 indexed citations
14.
Oldenburg, Johannes, Jean‐Maurice Lavergne, Michael Ludwig, et al.. (2001). Somatic Mosaicism in Hemophilia A: A Fairly Common Event. The American Journal of Human Genetics. 69(1). 75–87. 97 indexed citations
15.
Fregin, Andreas, Simone Rost, Werner Wolz, et al.. (2000). Congenital Deficiency of Vitamin K Dependent Coagulation Factors in Two Families Presents as a Genetic Defect of the Vitamin K-Epoxide-Reductase-Complex. Thrombosis and Haemostasis. 84(12). 937–941. 67 indexed citations
16.
Müller, C R, et al.. (1999). Allelic heterogeneity of alkaptonuria in Central Europe. European Journal of Human Genetics. 7(6). 645–651. 24 indexed citations
17.
Oldenburg, Johannes, Andreas Fregin, Wolfram Kreß, et al.. (1997). Missense mutations at ALA‐10 in the factor IX propeptide: an insignificant variant in normal life but a decisive cause of bleeding during oral anticoagulant therapy. British Journal of Haematology. 98(1). 240–244. 60 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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