Alex J. Eustace

1.9k citations

56 papers · 1.5k · 1 hit paper · h-index 21

Impact in

Cancer Research top 5%
- Cancer, Hypoxia, and Metabolism
- MicroRNA in disease regulation
- Cancer, Lipids, and Metabolism
- Cancer-related molecular mechanisms research
Oncology top 10%
- HER2/EGFR in Cancer Research
- Cancer Cells and Metastasis

Papers in

Oncology 28
- HER2/EGFR in Cancer Research 17
- Peptidase Inhibition and Analysis 4
Radiology, Nuclear Medicine and Imaging 10
- Monoclonal and Polyclonal Antibodies Research 7

Co-authors: John P. Crown (24 shared papers)MARTIN M. CLYNES (6 shared papers)Norma O’Donovan (15 shared papers)Martina S.J. McDermott (4 shared papers)Denis Martin Collins (12 shared papers)Laura Breen (2 shared papers)Britta Stordal (1 shared paper)Bryan T. Hennessy (13 shared papers)
Journals: British Journal of Cancer (6 papers)Breast Cancer Research and Treatment (4 papers)Therapeutic Advances in Medical Oncology (4 papers)Annals of Oncology (3 papers)Cancers (3 papers)
Partner nations: Ireland United States United Kingdom

In The Last Decade

Alex J. Eustace

53 papers receiving 1.5k citations

Alex J. Eustace's Hit Papers

align trajectories log scale

CARBON DOTS: Bioimaging and Anticancer Drug Delivery 2024 · 98 citations

What are hit papers?

Paper score: A paper's citations measured against the top-1% bar of its own field and year: the square root of citations ÷ bar, so 1 means right at the bar and 2 means four times its citations. The bar blends the citation counts that enter the top 1% of the paper's subfields in its year (weighted 89.5%), of those subfields over all years (0.5%) and of its year across all fields (10%); a subfield and year with fewer than 400 papers takes its year's bar. Papers from 2026 are not scored yet: in an unfinished year, when a paper appeared matters more than how it is cited.

Hit paper: A paper cited at least 1.5× the top-1% bar of its field and year: a paper score of at least √1.5.

2024 Chemistry - A European Journal

Peers

Countries citing papers authored by Alex J. Eustace

Since Specialization

Citations

This map shows the geographic impact of Alex J. Eustace's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alex J. Eustace with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alex J. Eustace more than expected).

Fields of papers citing papers by Alex J. Eustace

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alex J. Eustace. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alex J. Eustace. The network helps show where Alex J. Eustace may publish in the future.

Co-authors

The 25 scholars most cited alongside Alex J. Eustace, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Alex J. Eustace Line = papers co-authored together Alex J. Eustace links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 56 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	In vitro Development of Chemotherapy and Targeted Therapy Drug-Resistant Cancer Cell Lines: A Practical Guide with Case Studies Frontiers in Oncology ·Martina S.J. McDermott, Alex J. Eustace, Steven Busschots, Laura Breen, John P. Crown, MARTIN M. CLYNES, Norma Oâ€TMDonovan, Britta Stordal	2014	251
2	Enhanced stability of microRNA expression facilitates classification of FFPE tumour samples exhibiting near total mRNA degradation British Journal of Cancer ·John Hall, Janet Taylor, Helen R. Valentine, Joely J. Irlam, Alex J. Eustace, Peter Hoskin, Crispin J. Miller, Catharine Mary Louise West	2012	117
3	CARBON DOTS: Bioimaging and Anticancer Drug Delivery Chemistry - A European Journal ·Michał Bartkowski, Yingru Zhou, Mustafa Nabil Amin Mustafa, Alex J. Eustace, Silvia Giordani Hit paper breakdown →	2024	98
4	The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells BMC Cancer ·Sharon Anneve Glynn, DERMOT A. O'SULLIVAN, Alex J. Eustace, MARTIN M. CLYNES, Norma O’Donovan	2008	92
5	Preclinical evaluation of dasatinib, a potent Src kinase inhibitor, in melanoma cell lines Journal of Translational Medicine ·Alex J. Eustace, John P. Crown, MARTIN M. CLYNES, Norma O’Donovan	2008	74
6	HER2-family signalling mechanisms, clinical implications and targeting in breast cancer Breast Cancer Research and Treatment ·Naomi Elster, Denis Martin Collins, Sinéad Toomey, John P. Crown, Alex J. Eustace, Bryan T. Hennessy	2014	74
7	Effects of HER Family–targeting Tyrosine Kinase Inhibitors on Antibody-dependent Cell-mediated Cytotoxicity in HER2-expressing Breast Cancer Clinical Cancer Research ·Denis Martin Collins, Stephen F. Madden, Nicola Gaynor, Dalal AlSultan, Marion Le Gal, Alex J. Eustace, Kathy A. Gately, Clare Hughes	2020	56
8	Contribution of HIF-1 and drug penetrance to oxaliplatin resistance in hypoxic colorectal cancer cells British Journal of Cancer ·Darren L. Roberts, Kaye Janine Williams, Rachel Cowen, Monika Baráthová, Alex J. Eustace, S Brittain-Dissont, Michael J. Tilby, David Graham Pearson	2009	46
9	Metabolomic studies of human lung carcinoma cell lines using in vitro1H NMR of whole cells and cellular extracts NMR in Biomedicine ·Michael E. Gottschalk, Galya I. Ivanova, Denis Martin Collins, Alex J. Eustace, Robert A. O'Connor, Dermot F. Brougham	2008	42
10	A preclinical evaluation of the PI3K alpha/delta dominant inhibitor BAY 80-6946 in HER2-positive breast cancer models with acquired resistance to the HER2-targeted therapies trastuzumab and lapatinib Breast Cancer Research and Treatment ·Naomi Elster, Mattia Cremona, Clare P. Morgan, Sinéad Toomey, Aoife Carr, A O’Grady, Bryan T. Hennessy, Alex J. Eustace	2014	42
11	Evaluation of IGF1R and phosphorylated IGF1R as targets in HER2-positive breast cancer cell lines and tumours Breast Cancer Research and Treatment ·Brigid C. Browne, Alex J. Eustace, Susan Kennedy, Neil A. O’Brien, Kasper Tholstrup Pedersen, Martina S.J. McDermott, Annemarie Larkin, Jo Ballot	2012	35
12	Expression of hypoxia-inducible factor-1α predicts benefit from hypoxia modification in invasive bladder cancer British Journal of Cancer ·Benjamin Hunter, Alex J. Eustace, Joely J. Irlam, Helen R. Valentine, Helen Denley, Ken Oguejiofor, RICHARD F. SWINDELL, Peter Hoskin	2014	35
13	Membrane transport proteins in human melanoma: associations with tumour aggressiveness and metastasis British Journal of Cancer ·Naomi Walsh, Susan Kennedy, A. Larkin, Dimitrios J. Tryfonopoulos, Alex J. Eustace, Thamir Mahgoub, Caroline Conway, Irene K. Oglesby	2010	34
14	Preclinical evaluation of a novel triple-acting PIM/PI3K/mTOR inhibitor, IBL-302, in breast cancer Oncogene ·Sean P. Kennedy, Michael F. O‘Neill, Darren Cunningham, Patrick Glyn Morris, Sinéad Toomey, Carmen Blanco‐Aparicio, Sonia Martı́nez, Joaquı́n Pastor	2020	32
15	Impact of somatic PI3K pathway and ERBB family mutations on pathological complete response (pCR) in HER2-positive breast cancer patients who received neoadjuvant HER2-targeted therapies Breast Cancer Research ·Sinéad Toomey, Alex J. Eustace, Joanna Fay, Katherine M. Sheehan, Aoife Carr, Małgorzata Milewska, Stephen F. Madden, Ausra Teiserskiene	2017	31
16	Combined targeting EGFR and SRC as a potential novel therapeutic approach for the treatment of triple negative breast cancer Therapeutic Advances in Medical Oncology ·Alexandra Canonici, Alacoque L. Browne, Mohamed F. K. Ibrahim, Kevin P. Fanning, Sandra Roche, Neil T. Conlon, Fiona O’Neill, Justine Meiller	2020	28
17	Artificial Neural Networks for Classification in Metabolomic Studies of Whole Cells Using 1H Nuclear Magnetic Resonance BioMed Research International ·Dermot F. Brougham, Galya I. Ivanova, Michael E. Gottschalk, Denis Martin Collins, Alex J. Eustace, Robert A. O'Connor, Josef Havel	2010	26
18	Development of acquired resistance to lapatinib may sensitise HER2-positive breast cancer cells to apoptosis induction by obatoclax and TRAIL BMC Cancer ·Alex J. Eustace, Neil T. Conlon, Martina S.J. McDermott, Brigid C. Browne, Patrick C. O’Leary, Frankie Ann Holmes, Virginia A. Espina, Lance A. Liotta	2018	24
19	Growth factor receptor/steroid receptor cross talk in trastuzumab-treated breast cancer Oncogene ·Dearbhaile Catherine Collins, Sinéad Cocchiglia, Paul Tibbitts, Gemma Solon, F Bane, Jean McBryan, Achim Treumann, Alex J. Eustace	2014	23
20	The novel low molecular weight MYC antagonist MYCMI-6 inhibits proliferation and induces apoptosis in breast cancer cells Investigational New Drugs ·Dalal AlSultan, Emma L. Kavanagh, Shane O’Grady, Alex J. Eustace, Alina Castell, Lars‐Gunnar Larsson, John P. Crown, Stephen F. Madden	2020	22

About Alex J. Eustace

Alex J. Eustace is a scholar working on Oncology, Radiology, Nuclear Medicine and Imaging, Molecular Biology, Cancer Research and Pulmonary and Respiratory Medicine, having authored 56 papers that have together received 1.5k indexed citations. Recurring topics across this work include HER2/EGFR in Cancer Research (17 papers), Monoclonal and Polyclonal Antibodies Research (7 papers), Melanoma and MAPK Pathways (5 papers), Peptidase Inhibition and Analysis (4 papers), Lung Cancer Treatments and Mutations (4 papers), Computational Drug Discovery Methods (3 papers), Advanced Breast Cancer Therapies (3 papers) and Growth Hormone and Insulin-like Growth Factors (3 papers). The work is most often cited by research in Cancer Research (342 citations), Oncology (473 citations), Molecular Biology (681 citations), Pulmonary and Respiratory Medicine (170 citations) and Genetics (55 citations). Alex J. Eustace has collaborated with scholars based in Ireland, United States and United Kingdom. Frequent co-authors include John P. Crown, MARTIN M. CLYNES, Norma O’Donovan, Martina S.J. McDermott, Denis Martin Collins, Laura Breen, Britta Stordal, Bryan T. Hennessy, Sinéad Toomey and Joely J. Irlam. Their work appears in journals such as British Journal of Cancer, Breast Cancer Research and Treatment, Therapeutic Advances in Medical Oncology, Annals of Oncology and Cancers.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Alex J. Eustace

Alex J. Eustace's Hit Papers

Peers

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Fields of papers citing papers by Alex J. Eustace

All Works

About Alex J. Eustace

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