Alan Wilhelm

631 citations

22 papers · 388 indexed · h-index 9

Impact in

Oncology top 10%
- CAR-T cell therapy research
- HER2/EGFR in Cancer Research
- Cancer Treatment and Pharmacology
Hematology top 10%
- Acute Myeloid Leukemia Research

Papers in ⓘ

Radiology, Nuclear Medicine and Imaging 11
- Monoclonal and Polyclonal Antibodies Research 11
Oncology 12
- HER2/EGFR in Cancer Research 11
- CAR-T cell therapy research 2

Co-authors: Yelena Kovtun (7 shared papers)Ravi Chari (11 shared papers)Nicholas C. Yoder (7 shared papers)Lauren Harvey (6 shared papers)Chen Bai (7 shared papers)Erin K. Maloney (11 shared papers)Jan Pinkas (5 shared papers)Victor S. Goldmacher (3 shared papers)
Journals: Blood (6 papers)Cancer Research (4 papers)Molecular Cancer Therapeutics (2 papers)ACS Medicinal Chemistry Letters (2 papers)Molecular Pharmaceutics (2 papers)
Partner nations: United States Netherlands

In The Last Decade

Alan Wilhelm

21 papers receiving 372 citations

Peers

Countries citing papers authored by Alan Wilhelm

Since Specialization

Citations

This map shows the geographic impact of Alan Wilhelm's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alan Wilhelm with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alan Wilhelm more than expected).

Fields of papers citing papers by Alan Wilhelm

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alan Wilhelm. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alan Wilhelm. The network helps show where Alan Wilhelm may publish in the future.

Co-authors

The 25 scholars most cited alongside Alan Wilhelm, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Alan Wilhelm Line = papers co-authored together Alan Wilhelm links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 22 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	A CD123-targeting antibody-drug conjugate, IMGN632, designed to eradicate AML while sparing normal bone marrow cells Blood Advances ·Yelena Kovtun, Gregory E. Jones, Sharlene Adams, Lauren Harvey, Charlene A. Audette, Alan Wilhelm, Chen Bai, Lingyun Rui, Rassol Laleau, Liu Fenghua, Olga Ab, Yulius Y. Setiady, Nicholas C. Yoder, Victor S. Goldmacher, Ravi Chari, Jan Pinkas, Thomas Chittenden	2018	129
2	A New Class of Antibody–Drug Conjugates with Potent DNA Alkylating Activity Molecular Cancer Therapeutics ·Michael L. Miller, Nathan Fishkin, Wěi Li, Kathleen R. Whiteman, Yelena Kovtun, Emily E. Reid, Katie E. Archer, Erin K. Maloney, Charlene A. Audette, Michele Mayo, Alan Wilhelm, Holly A. Modafferi, Rajeeva Singh, Jan Pinkas, Victor S. Goldmacher, John M. Lambert, Ravi Chari	2016	65
3	Optimizing Lysosomal Activation of Antibody–Drug Conjugates (ADCs) by Incorporation of Novel Cleavable Dipeptide Linkers Molecular Pharmaceutics ·Paulin Salomon, Emily E. Reid, Katie E. Archer, Luke Harris, Erin K. Maloney, Alan Wilhelm, Michael L. Miller, Ravi Chari, Thomas A. Keating, Rajeeva Singh	2019	33
4	A Case Study Comparing Heterogeneous Lysine- and Site-Specific Cysteine-Conjugated Maytansinoid Antibody-Drug Conjugates (ADCs) Illustrates the Benefits of Lysine Conjugation Molecular Pharmaceutics ·Nicholas C. Yoder, Chen Bai, Daniel Tavares, Wayne C. Widdison, Kathleen R. Whiteman, Alan Wilhelm, Sharon Wilhelm, Molly A. McShea, Erin K. Maloney, Olga Ab, Lintao Wang, Shan Jin, Hans K. Erickson, Thomas A. Keating, John M. Lambert	2019	30
5	The Antibody-Drug Conjugate (ADC) IMGN779 Is Highly Active in Vitro and in Vivo Against Acute Myeloid Leukemia (AML) with FLT3-ITD Mutations Blood ·Kathleen R. Whiteman, Paul Noordhuis, R. Walker, Krystal Watkins, Yelena Kovtun, Lauren Harvey, Alan Wilhelm, Holly A. Johnson, Gerrit Jan Schuurhuis, Gert J. Ossenkoppele, Robert J. Lutz	2014	29
6	Site-Specific Conjugation of the Indolinobenzodiazepine DGN549 to Antibodies Affords Antibody–Drug Conjugates with an Improved Therapeutic Index as Compared with Lysine Conjugation Bioconjugate Chemistry ·Chen Bai, Emily E. Reid, Alan Wilhelm, Manami Shizuka, Erin K. Maloney, Rassol Laleau, Lauren Harvey, Katie E. Archer, Dilrukshi Vitharana, Sharlene Adams, Yelena Kovtun, Michael L. Miller, Ravi Chari, Thomas A. Keating, Nicholas C. Yoder	2019	20
7	IMGN632: A CD123-Targeting Antibody-Drug Conjugate (ADC) with a Novel DNA-Alkylating Payload, Is Highly Active and Prolongs Survival in Acute Myeloid Leukemia (AML) Xenograft Models Blood ·Sharlene Adams, Alan Wilhelm, Lauren Harvey, Chen Bai, Nicholas C. Yoder, Yelena Kovtun, Thomas Chittenden, Jan Pinkas	2016	13
8	Effect of Linker Stereochemistry on the Activity of Indolinobenzodiazepine Containing Antibody–Drug Conjugates (ADCs) ACS Medicinal Chemistry Letters ·Emily E. Reid, Katie E. Archer, Manami Shizuka, Alan Wilhelm, Nicholas C. Yoder, Chen Bai, Nathan Fishkin, Luke Harris, Erin K. Maloney, Paulin Salomon, Erica Hong, Rui Wu, Olga Ab, Shan Jin, Katharine C. Lai, Surina Sikka, Ravi Chari, Michael L. Miller	2019	11
9	Synthesis of Highly Potent N-10 Amino-Linked DNA-Alkylating Indolinobenzodiazepine Antibody–Drug Conjugates (ADCs) ACS Medicinal Chemistry Letters ·Katie E. Archer, Emily E. Reid, Manami Shizuka, James R. Woods, Luke Harris, Erin K. Maloney, Laura M. Bartle, Olga Ab, Alan Wilhelm, Yulius Y. Setiady, Jose F. Ponte, Rajeeva Singh, Thomas A. Keating, Ravi Chari, Michael L. Miller	2019	9
10	Prime Editing Efficiently and Precisely Corrects Causative Mutation in Chronic Granulomatous Disease, Restoring Myeloid Function: Toward Development of a Prime Edited Autologous Hematopoietic Stem Cell Therapy Blood ·Jack Heath, Jacob Stuart Orenstein, Justin G Tedeschi, Allen C Ng, Maria D Collier, Julia Kushakji, Alan Wilhelm, Andrew Taylor, David P. Waterman, Suk See De Ravin, Harry L. Malech, Andrew V. Anzalone, Jeremy S. Duffield, Jennifer L. Gori	2023	8
11	Modulation der zytoplasmatischen Ca²⁺-Konzentration isolierter Myozyten des Detrusor vesicae durch Anticholinergika Aktuelle Urologie ·Roberta Eckert, Alan Wilhelm, Ulrich Schwantes, J. Utz, S. Alloussi, W. Trautwein, Manja Ziegler	1995	7
12	Multiplex Prime Editing and PASSIGE TM for Non-Viral Generation of an Allogeneic CAR-T Cell Product Blood ·Emily J. Pomeroy, Andrew V. Anzalone, Christopher J. Podracky, Noah B. Bloch, Ruina Chang, Arika A Dwivedi, Kanut Laoharawee, Alan Wilhelm, David P. Waterman, Justin Tedeschi, Upasana Sunil Arvindam, Elizabeth R. Macari, Jennifer L. Gori, Jeremy S. Duffield	2023	7
13	IMGN779, a Next Generation CD33-Targeting ADC, Combines Effectively with Cytarabine in Acute Myeloid Leukemia (AML) Preclinical Models, Resulting in Increased DNA Damage Response, Cell Cycle Arrest and Apoptosis In Vitro and Prolonged Survival In Vivo Blood ·Sharlene Adams, Meghan Kelly, Rebecca McCarthy, Alan Wilhelm, Krystal Watkins, Leanne Lanieri, Callum M. Sloss, Angela Romanelli	2017	6
14	Design, synthesis and evaluation of novel, potent DNA alkylating agents and their antibody-drug conjugates (ADCs) Bioorganic & Medicinal Chemistry Letters ·Emily E. Reid, Katie E. Archer, Manami Shizuka, Molly A. McShea, Erin K. Maloney, Olga Ab, Leanne Lanieri, Alan Wilhelm, Jose F. Ponte, Nicholas C. Yoder, Ravi Chari, Michael L. Miller	2019	5
15	A CD123-Targeting Antibody-Drug Conjugate (ADC), IMGN632, Designed to Eradicate Acute Myeloid Leukemia (AML) Cells While Sparing Normal Bone Marrow Cells Blood ·Yelena Kovtun, Gregory E. Jones, Charlene A. Audette, Lauren Harvey, Baudouin Gerard, Alan Wilhelm, Chen Bai, Sharlene Adams, Victor S. Goldmacher, Ravi Chari, Thomas Chittenden	2016	5
16	Abstract 2644: Antibody-drug conjugates (ADCs) with a novel DNA-alkylating agent, DGN462, are highly potent in vitro and in vivo against human cancer models Cancer Research ·Kathleen R. Whiteman, Charlene A. Audette, Andre Dandeneau, Megan Ellis, Nathan Fishkin, Lauren Harvey, Holly A. Johnson, Yelena Kovtun, Erin K. Maloney, Michael L. Miller, Alan Wilhelm, Ravi Chari	2014	4
17	Alternaria alternata induced inflammatory lung responses: a novel in vivo PK/PD model Journal of Inflammation ·Malgorzata A. Gil, Michael Caniga, Joseph Eckman, Robbie L. McLeod, Lily Y. Moy, Alan Wilhelm, Janice D. Woodhouse, Jie Zhang-Hoover, Milenko Cicmil	2013	3
18	Characterization of a Novel, Potent and Selective Small Molecule Spleen Tyrosine Kinase (SYK) Inhibitor in In Vitro and In Vivo Models of Asthma. Journal of Allergy and Clinical Immunology ·Michael A. Crackower, Lily Y. Moy, Yanlin Jia, Hongshi Yu, Stella Vincent, J. Richard Miller, Gissela Lieber, Xiomara Fernandez, Michael Caniga, Malgorzata A. Gil, Alan Wilhelm, Hani Houshyar, Alan B. Northrup, Richard W. Chapman, William M. Abraham, N. Kelly, Emily Hickey, Thomas A. Miller	2012	1
19	Abstract 4504: Plasma pharmacokinetics and tumor accumulation in mice of IMGN779, an antibody-drug conjugate for acute myeloid leukemia Cancer Research ·Katharine C. Lai, Prerak Shah, Surina Sikka, Xiuxia Sun, Rassol Laleau, Kathleen R. Whiteman, Holly Johnson-Modafferi, Alan Wilhelm, Charlene A. Audette, Lintao Wang, Megan Bogalhas, Thomas A. Keating, Ravi Chari	2015	1
20	Abstract 645: Stability and efficacy comparison of site-specific and lysine-linked maytansinoid antibody-drug conjugates Cancer Research ·Nicholas C. Yoder, Chen Bai, Daniel Tavares, Wayne C. Widdison, Olga Ab, Kathleen R. Whiteman, Alan Wilhelm, Erin K. Maloney, Hans K. Erickson, Thomas A. Keating	2015	1

About Alan Wilhelm

Alan Wilhelm is a scholar working on Radiology, Nuclear Medicine and Imaging, Oncology, Immunology and Allergy, Organic Chemistry and Hematology, having authored 22 papers that have together received 388 indexed citations. Recurring topics across this work include HER2/EGFR in Cancer Research (11 papers), Monoclonal and Polyclonal Antibodies Research (11 papers), Cancer therapeutics and mechanisms (7 papers), Synthesis and pharmacology of benzodiazepine derivatives (5 papers), CAR-T cell therapy research (2 papers), Asthma and respiratory diseases (2 papers), Chemical Synthesis and Analysis (2 papers) and Click Chemistry and Applications (2 papers). The work is most often cited by research in Oncology (273 citations), Hematology (104 citations), Radiology, Nuclear Medicine and Imaging (154 citations), Dermatology (28 citations) and Immunology (47 citations). Alan Wilhelm has collaborated with scholars based in United States and Netherlands. Frequent co-authors include Yelena Kovtun, Ravi Chari, Nicholas C. Yoder, Lauren Harvey, Chen Bai, Erin K. Maloney, Jan Pinkas, Victor S. Goldmacher, Sharlene Adams and Charlene A. Audette. Their work appears in journals such as Blood, Cancer Research, Molecular Cancer Therapeutics, ACS Medicinal Chemistry Letters and Molecular Pharmaceutics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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