Alan Melcher

16.2k total citations · 1 hit paper
245 papers, 10.5k citations indexed

About

Alan Melcher is a scholar working on Genetics, Oncology and Immunology. According to data from OpenAlex, Alan Melcher has authored 245 papers receiving a total of 10.5k indexed citations (citations by other indexed papers that have themselves been cited), including 158 papers in Genetics, 121 papers in Oncology and 92 papers in Immunology. Recurrent topics in Alan Melcher's work include Virus-based gene therapy research (157 papers), CAR-T cell therapy research (81 papers) and Immunotherapy and Immune Responses (68 papers). Alan Melcher is often cited by papers focused on Virus-based gene therapy research (157 papers), CAR-T cell therapy research (81 papers) and Immunotherapy and Immune Responses (68 papers). Alan Melcher collaborates with scholars based in United Kingdom, United States and Canada. Alan Melcher's co-authors include Richard G. Vile, Kevin J. Harrington, Hardev Pandha, Fiona Errington‐Mais, Peter J. Selby, Timothy Kottke, Jill Thompson, Rosa María Díaz, Robin Prestwich and Elizabeth J. Ilett and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and The Lancet.

In The Last Decade

Alan Melcher

238 papers receiving 10.3k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Inflammatory microenvironment remodelling by tumour cells after radiotherapy

2020 601 citations Martin McLaughlin, Emmanuel C. Patin et al. Nature reviews. Cancer profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author						Papers	Cites
Alan Melcher	5.6k	5.5k	3.7k	3.6k	1.7k	245	10.5k
Richard G. Vile	8.2k 1.5×	6.0k 1.1×	6.2k 1.7×	3.9k 1.1×	1.9k 1.1×	278	13.7k
Hardev Pandha	4.0k 0.7×	3.6k 0.7×	3.4k 0.9×	1.8k 0.5×	1.2k 0.7×	223	7.8k
David H. Kirn	12.1k 2.2×	8.9k 1.6×	8.6k 2.3×	1.8k 0.5×	1.6k 0.9×	144	15.8k
Akseli Hemminki	7.2k 1.3×	8.9k 1.6×	6.3k 1.7×	1.6k 0.4×	972 0.6×	348	14.9k
Ramón Alemany	6.2k 1.1×	4.7k 0.9×	5.0k 1.3×	893 0.2×	828 0.5×	162	8.3k
Patrick W.K. Lee	3.3k 0.6×	2.2k 0.4×	2.6k 0.7×	796 0.2×	2.3k 1.3×	91	6.5k
Dmitriy Zamarin	1.5k 0.3×	2.8k 0.5×	1.7k 0.5×	3.0k 0.8×	825 0.5×	145	7.1k
J. Ignacio Casal	1.4k 0.2×	1.4k 0.3×	3.9k 1.0×	1.2k 0.3×	1.2k 0.7×	167	7.4k
Jon M. Huibregtse	2.5k 0.5×	5.7k 1.0×	8.9k 2.4×	2.5k 0.7×	661 0.4×	85	14.7k
Jean Rommelaere	5.8k 1.0×	2.3k 0.4×	3.2k 0.9×	940 0.3×	3.0k 1.7×	253	7.7k

Countries citing papers authored by Alan Melcher

Since Specialization

Citations

This map shows the geographic impact of Alan Melcher's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alan Melcher with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alan Melcher more than expected).

Fields of papers citing papers by Alan Melcher

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alan Melcher. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alan Melcher. The network helps show where Alan Melcher may publish in the future.

Co-authorship network of co-authors of Alan Melcher

This figure shows the co-authorship network connecting the top 25 collaborators of Alan Melcher. A scholar is included among the top collaborators of Alan Melcher based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alan Melcher. Alan Melcher is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Hak, Charleen Chan Wah, Emmanuel C. Patin, Annalisa Nicastri, et al.. (2025). Xevinapant plus Chemoradiotherapy Negatively Sculpts the Tumor-Immune Microenvironment in Head and Neck Cancer. Cancer Research Communications. 5(11). 2079–2091.

Jennings, Victoria A., G Migneco, Nicola Ingram, et al.. (2024). Enhancing oncolytic virotherapy by extracellular vesicle mediated microRNA reprogramming of the tumour microenvironment. Frontiers in Immunology. 15. 1500570–1500570. 1 indexed citations

Foo, Shane, Pablo Nenclares, Martin McLaughlin, et al.. (2024). Combination of oncolytic Maraba virus with immune checkpoint blockade overcomes therapy resistance in an immunologically cold model of advanced melanoma with dysfunctional T-cell receptor signalling. Journal for ImmunoTherapy of Cancer. 12(7). e009443–e009443. 5 indexed citations

Bergerhoff, Katharina, Shane Foo, Emmanuel C. Patin, et al.. (2020). Combining BRAF inhibition with oncolytic herpes simplex virus enhances the immune-mediated antitumor therapy of BRAF-mutant thyroid cancer. Journal for ImmunoTherapy of Cancer. 8(2). e000698–e000698. 24 indexed citations

McLaughlin, Martin, Emmanuel C. Patin, Malin Pedersen, et al.. (2020). Inflammatory microenvironment remodelling by tumour cells after radiotherapy. Nature reviews. Cancer. 20(4). 203–217. 601 indexed citations breakdown →

Loga, Katharina von, Andrew Woolston, B Griffiths, et al.. (2020). Computational Image Analysis of T-Cell Infiltrates in Resectable Gastric Cancer: Association with Survival and Molecular Subtypes. JNCI Journal of the National Cancer Institute. 113(1). 88–98. 16 indexed citations

Annels, Nicola, David Mansfield, Carmen Ballesteros‐Merino, et al.. (2019). Phase I Trial of an ICAM-1-Targeted Immunotherapeutic-Coxsackievirus A21 (CVA21) as an Oncolytic Agent Against Non Muscle-Invasive Bladder Cancer. Clinical Cancer Research. 25(19). 5818–5831. 97 indexed citations

Smith, Henry, David Mansfield, Victoria Roulstone, et al.. (2019). PD-1 Blockade Following Isolated Limb Perfusion with Vaccinia Virus Prevents Local and Distant Relapse of Soft-tissue Sarcoma. Clinical Cancer Research. 25(11). 3443–3454. 23 indexed citations

Evgin, Laura, Amanda L. Huff, Timothy Kottke, et al.. (2019). Suboptimal T-cell Therapy Drives a Tumor Cell Mutator Phenotype That Promotes Escape from First-Line Treatment. Cancer Immunology Research. 7(5). 828–840. 13 indexed citations

10.

Dillon, Magnus T., Katharina Bergerhoff, Malin Pedersen, et al.. (2019). ATR Inhibition Potentiates the Radiation-induced Inflammatory Tumor Microenvironment. Clinical Cancer Research. 25(11). 3392–3403. 146 indexed citations

11.

Wilkins, Anna, Emmanuel C. Patin, Kevin J. Harrington, & Alan Melcher. (2019). The immunological consequences of radiation‐induced DNA damage. The Journal of Pathology. 247(5). 606–614. 44 indexed citations

12.

Stead, Lucy F., Jérémie Nsengimana, Alastair Droop, et al.. (2019). Expression profiling of single cells and patient cohorts identifies multiple immunosuppressive pathways and an altered NK cell phenotype in glioblastoma. Clinical & Experimental Immunology. 200(1). 33–44. 54 indexed citations

13.

Khan, Aadil, James Paget, Martin McLaughlin, et al.. (2018). Genetically modified lentiviruses that preserve microvascular function protect against late radiation damage in normal tissues. Science Translational Medicine. 10(425). 17 indexed citations

14.

Roulstone, Victoria, Khurum Khan, Hardev Pandha, et al.. (2014). Phase I Trial of Cyclophosphamide as an Immune Modulator for Optimizing Oncolytic Reovirus Delivery to Solid Tumors. Clinical Cancer Research. 21(6). 1305–1312. 42 indexed citations

15.

Tai, Lee‐Hwa, Jiqing Zhang, Karen J. Scott, et al.. (2013). Perioperative Influenza Vaccination Reduces Postoperative Metastatic Disease by Reversing Surgery-Induced Dysfunction in Natural Killer Cells. Clinical Cancer Research. 19(18). 5104–5115. 56 indexed citations

16.

Karapanagiotou, Eleni, Victoria Roulstone, Katie Twigger, et al.. (2012). Phase I/II Trial of Carboplatin and Paclitaxel Chemotherapy in Combination with Intravenous Oncolytic Reovirus in Patients with Advanced Malignancies. Clinical Cancer Research. 18(7). 2080–2089. 151 indexed citations

17.

Harrington, Kevin J., Eleni Karapanagiotou, Victoria Roulstone, et al.. (2010). Two-Stage Phase I Dose-Escalation Study of Intratumoral Reovirus Type 3 Dearing and Palliative Radiotherapy in Patients with Advanced Cancers. Clinical Cancer Research. 16(11). 3067–3077. 94 indexed citations

18.

Twigger, Katie, Laura Vidal, Christine L. White, et al.. (2008). Enhanced In vitro and In vivo Cytotoxicity of Combined Reovirus and Radiotherapy. Clinical Cancer Research. 14(3). 912–923. 88 indexed citations

19.

Hingorani, Mohan, Christine L. White, Martin Gore, et al.. (2008). Inhibition of Repair of Radiation-Induced DNA Damage Enhances Gene Expression from Replication-Defective Adenoviral Vectors. Cancer Research. 68(23). 9771–9778. 20 indexed citations

20.

Hingorani, Mohan, Christine L. White, Shane Zaidi, et al.. (2008). Radiation-Mediated Up-Regulation of Gene Expression from Replication-Defective Adenoviral Vectors: Implications for Sodium Iodide Symporter Gene Therapy. Clinical Cancer Research. 14(15). 4915–4924. 29 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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