Alan J. Paine

2.9k citations

72 papers · 2.4k indexed · 1 hit paper · h-index 28

Pharmacology top 0.2%
Molecular Biology
Oncology top 10%
Hepatology top 2%
Health, Toxicology and Mutagenesis top 2%

Co-authors: A.D. Dayan Matthew C. Wright R.F. Legg Brian G. Lake Pia Villa David N. Skilleter Bas J. Blaauboer Evangelos Andreakos
Topics: Pharmacogenetics and Drug Metabolism (30 papers)Drug-Induced Hepatotoxicity and Protection (15 papers)Liver physiology and pathology (13 papers)
Cited by: Pharmacology Hepatology Health, Toxicology and Mutagenesis
Journals: Biochemical Journal Biochemical and Biophysical Research Communications Annals of the New York Academy of Sciences
Partner nations: United Kingdom Netherlands Austria

In The Last Decade

Alan J. Paine

71 papers receiving 2.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Mechanisms of chromium toxicity, carcinogenicity and allergenicity: Review of the literature from 1985 to 2000

2001 524 citations A.D. Dayan, Alan J. Paine Human & Experimental Toxicology profile →

Peers

Countries citing papers authored by Alan J. Paine

Since Specialization

Citations

This map shows the geographic impact of Alan J. Paine's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alan J. Paine with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alan J. Paine more than expected).

Fields of papers citing papers by Alan J. Paine

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alan J. Paine. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alan J. Paine. The network helps show where Alan J. Paine may publish in the future.

Co-authorship network of co-authors of Alan J. Paine

This figure shows the co-authorship network connecting the top 25 collaborators of Alan J. Paine. A scholar is included among the top collaborators of Alan J. Paine based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alan J. Paine. Alan J. Paine is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Transesterification ofp-hydroxybenzoate esters (parabens) by human intestinal (Caco-2) cells 2006 ·Xenobiotica ·(unknown),Alan J. Paine,David Lockley,David J. Sanders,Ruth Pendlington,Ben Forbes	16
2	RNA interference mediated in human primary cells via recombinant baculoviral vectors 2005 ·Molecular Therapy ·Linda Nicholson,(unknown),Alan J. Paine,Derek A. Mann,Colin T. Dolphin	46
3	Activation of signalling pathways during hepatocyte isolation: relevance to toxicology in vitro 2003 ·Toxicology in Vitro ·Alan J. Paine,Evangelos Andreakos	45
4	Rapid Induction of NF-κB Binding during Liver Cell Isolation and Culture: Inhibition byL-NAMEIndicates a Role for Nitric Oxide Synthase 1999 ·Biochemical and Biophysical Research Communications ·Antonio Rodríguez‐Ariza,Alan J. Paine	27
5	Developmental changes in the constitutive and inducible expression of cytochrome p450 3a2 1997 ·Biochemical Pharmacology ·Matthew C. Wright,Robert J. Edwards,(unknown),Vera Ribeiro,Gurpreet S. Ratra,Maria Celeste Lechner,Alan J. Paine	30
6	Glucocorticoid receptor-independent transcriptional induction of cytochrome P450 3A1 by metyrapone and its potentiation by glucocorticoid. 1996 ·Molecular Pharmacology ·Matthew C. Wright,Xiu Jun Wang,(unknown),Vera Ribeiro,Alan J. Paine,(unknown)	36
7	Induction of the Cytochrome P450 3A Subfamily in Rat Liver Correlates with the Binding of Inducers to a Microsomal Protein 1994 ·Biochemical and Biophysical Research Communications ·Matthew C. Wright,Alan J. Paine	28
8	Environmentally friendly bacteria? 1994 ·Human & Experimental Toxicology ·Alan J. Paine	1
9	Alteration of Transcription Factor mRNAs during the Isolation and Culture of Rat Hepatocytes Suggests the Activation of a Proliferative Mode Underlies Their Dedifferentiation 1993 ·Biochemical and Biophysical Research Communications ·(unknown),(unknown),Xiu Jun Wang,Stuart M. Raleigh,Matthew C. Wright,Alan J. Paine	61
10	Resistance of precision-cut liver slices to the toxic effects of menadione 1992 ·Toxicology in Vitro ·Matthew C. Wright,Alan J. Paine	17
11	Evidence that the loss of rat liver cytochrome P450 in vitro is not solely associated with the use of collagenase, the loss of cell-cell contacts and/or the absence of an extracellular matrix 1992 ·Biochemical Pharmacology ·Matthew C. Wright,Alan J. Paine	55
12	The mechanism of hepatic uptake of a radiolabelled monoclonal antibody 1992 ·International Journal of Cancer ·(unknown),Alan J. Paine,Stephen J. Mather	22
13	The role of lymphocyte production and migration in the lymphopenia caused by 2-acetyl-4-tetrahydroxy-butyl imidazole 1992 ·International Journal of Immunopharmacology ·Stéphanie Gobin,R.F. Legg,Alan J. Paine	9
14	The maintenance of cytochrome P-450 in rat hepatocyte culture: Some applications of liver cell cultures to the study of drug metabolism, toxicity and the induction of the P-450 system 1990 ·Chemico-Biological Interactions ·Alan J. Paine	141
15	Effect of pyridoxine on the disposition and lymphopenic effects of 2-acetyl-4(5)-tetrahydroxybutyl imidazole in the rat 1990 ·Xenobiotica ·J. A. Phillips,Alan J. Paine	18
16	Advances in applied toxicology 1989 ·Taylor & Francis eBooks ·A.D. Dayan,Alan J. Paine	6
17	Effect of oral and parenteral administration of B6 vitamers on the lymphopenia produced by feeding ammonia caramel or 2-acetyl-4(5)-(1,2,3,4-tetrahydroxy)butylimidazole to rats 1989 ·Food and Chemical Toxicology ·(unknown),Alan J. Paine	15
18	The effect of 2-acetyl-4-tetrahydroxybutylimidazole on lymphocyte subsets in peripheral blood of the rat 1989 ·International Journal of Immunopharmacology ·Stéphanie Gobin,R.F. Legg,Alan J. Paine,J. A. Phillips	17
19	Induction of hepatic cytochrome P-450 and drug metabolism by metyrapone in the rat: relevance to its effects in rat-liver cell culture 1983 ·Xenobiotica ·Brian G. Lake,Alan J. Paine	27
20	Ligands maintain cytochrome P-450 in liver cell culture by affecting its synthesis and degradation 1980 ·Biochemical and Biophysical Research Communications ·Alan J. Paine,Pia Villa	26

About Alan J. Paine

Alan J. Paine is a scholar working on Pharmacology, Hepatology and Biochemistry, having authored 72 papers that have together received 2.4k indexed citations. Recurring topics across this work include Pharmacogenetics and Drug Metabolism (30 papers), Drug-Induced Hepatotoxicity and Protection (15 papers) and Liver physiology and pathology (13 papers). The work is most often cited by research in Pharmacology (881 citations), Hepatology (408 citations) and Health, Toxicology and Mutagenesis (369 citations). Alan J. Paine has collaborated with scholars based in United Kingdom, Netherlands and Austria. Frequent co-authors include A.D. Dayan, Matthew C. Wright, R.F. Legg, Brian G. Lake, Pia Villa, David N. Skilleter, Bas J. Blaauboer, Evangelos Andreakos, AndréE.M. McLean and Fiorenzo Stirpe. Their work appears in journals such as Biochemical Journal, Biochemical and Biophysical Research Communications and Annals of the New York Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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