Alan Holmes

5.7k total citations · 3 hit papers
42 papers, 4.4k citations indexed

About

Alan Holmes is a scholar working on Molecular Biology, Pathology and Forensic Medicine and Pulmonary and Respiratory Medicine. According to data from OpenAlex, Alan Holmes has authored 42 papers receiving a total of 4.4k indexed citations (citations by other indexed papers that have themselves been cited), including 21 papers in Molecular Biology, 20 papers in Pathology and Forensic Medicine and 18 papers in Pulmonary and Respiratory Medicine. Recurrent topics in Alan Holmes's work include Systemic Sclerosis and Related Diseases (20 papers), Pulmonary Hypertension Research and Treatments (16 papers) and Connective Tissue Growth Factor Research (14 papers). Alan Holmes is often cited by papers focused on Systemic Sclerosis and Related Diseases (20 papers), Pulmonary Hypertension Research and Treatments (16 papers) and Connective Tissue Growth Factor Research (14 papers). Alan Holmes collaborates with scholars based in United Kingdom, United States and Canada. Alan Holmes's co-authors include David Abraham, Andrew Leask, Carol M. Black, Shiwen Xu, Christopher P. Denton, A Gilbane, David C. Budd, Christoph Walker, Nicholas W. Morrell and Susan Sa and has published in prestigious journals such as New England Journal of Medicine, Journal of Biological Chemistry and Circulation.

In The Last Decade

Alan Holmes

41 papers receiving 4.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Elevated Levels of Inflammatory Cytokines Predict Survival in Idiopathic and Familial Pulmonary Arterial Hypertension

2010 588 citations Elaine Soon, Alan Holmes et al. Circulation profile →
Endothelial to Mesenchymal Transition Contributes to Endothelial Dysfunction in Pulmonary Arterial Hypertension

2015 274 citations Robert B. Good, A Gilbane et al. American Journal Of Pathology profile →
Does age matter? The impact of rodent age on study outcomes

2016 249 citations Alan Holmes et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Alan Holmes United Kingdom	27	2.1k	1.9k	1.1k	610	444	42	4.4k
Asish K. Ghosh United States	30	1.8k 0.9×	516 0.3×	512 0.5×	649 1.1×	393 0.9×	46	3.7k
Clara Dees Germany	43	2.5k 1.2×	1.3k 0.7×	2.2k 2.0×	240 0.4×	1.2k 2.6×	85	5.8k
Pawel Zerr Germany	31	1.6k 0.8×	769 0.4×	1.3k 1.2×	153 0.3×	662 1.5×	39	3.4k
Swati Bhattacharyya United States	34	1.4k 0.7×	804 0.4×	1.5k 1.4×	155 0.3×	760 1.7×	56	3.5k
Alfiya Akhmetshina Germany	29	1.7k 0.8×	724 0.4×	1.4k 1.3×	144 0.2×	664 1.5×	37	3.6k
Thierry Maisonobe France	47	1.3k 0.7×	517 0.3×	327 0.3×	302 0.5×	449 1.0×	195	5.9k
Yasushi Kawaguchi Japan	39	813 0.4×	916 0.5×	1.3k 1.2×	133 0.2×	1.3k 2.8×	141	4.1k
Brendan C. Dickson Canada	43	1.4k 0.7×	3.4k 1.8×	1.1k 1.0×	659 1.1×	130 0.3×	221	6.4k
Alfiya Distler Germany	29	1.3k 0.6×	622 0.3×	1.0k 1.0×	106 0.2×	549 1.2×	55	2.9k
Gaetano Magro Italy	39	1.5k 0.7×	1.0k 0.5×	792 0.7×	83 0.1×	506 1.1×	300	5.7k

Countries citing papers authored by Alan Holmes

Since Specialization

Citations

This map shows the geographic impact of Alan Holmes's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alan Holmes with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alan Holmes more than expected).

Fields of papers citing papers by Alan Holmes

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alan Holmes. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alan Holmes. The network helps show where Alan Holmes may publish in the future.

Co-authorship network of co-authors of Alan Holmes

This figure shows the co-authorship network connecting the top 25 collaborators of Alan Holmes. A scholar is included among the top collaborators of Alan Holmes based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alan Holmes. Alan Holmes is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Tam, Angela, Sarah L. Trinder, Korsa Khan, et al.. (2021). Selective deletion of connective tissue growth factor attenuates experimentally-induced pulmonary fibrosis and pulmonary arterial hypertension. The International Journal of Biochemistry & Cell Biology. 134. 105961–105961. 19 indexed citations

Trinder, Sarah L., Myriam Labelle, Manuel Rodriguez‐Justo, et al.. (2020). Platelet‐derived transforming growth factor‐β1 promotes keratinocyte proliferation in cutaneous wound healing. Journal of Tissue Engineering and Regenerative Medicine. 14(4). 645–649. 45 indexed citations

Gilbane, A, Emma Derrett‐Smith, Sarah L. Trinder, et al.. (2015). Impaired Bone Morphogenetic Protein Receptor II Signaling in a Transforming Growth Factor-β–Dependent Mouse Model of Pulmonary Hypertension and in Systemic Sclerosis. American Journal of Respiratory and Critical Care Medicine. 191(6). 665–677. 38 indexed citations

Good, Robert B., A Gilbane, Sarah L. Trinder, et al.. (2015). Endothelial to Mesenchymal Transition Contributes to Endothelial Dysfunction in Pulmonary Arterial Hypertension. American Journal Of Pathology. 185(7). 1850–1858. 274 indexed citations breakdown →

Gilbane, A, Christopher P. Denton, & Alan Holmes. (2013). Scleroderma pathogenesis: a pivotal role for fibroblasts as effector cells. Arthritis Research & Therapy. 15(3). 215–215. 142 indexed citations

Davies, Rachel, Alan Holmes, John Deighton, et al.. (2012). BMP type II receptor deficiency confers resistance to growth inhibition by TGF-β in pulmonary artery smooth muscle cells: role of proinflammatory cytokines. American Journal of Physiology-Lung Cellular and Molecular Physiology. 302(6). L604–L615. 98 indexed citations

Ciuclan, Loredana, Olivier Bonneau, Martin Hussey, et al.. (2011). A Novel Murine Model of Severe Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine. 184(10). 1171–1182. 205 indexed citations

Holmes, Alan, Markella Ponticos, Shiwen Xu, Christopher P. Denton, & David Abraham. (2011). Elevated CCN2 expression in scleroderma: a putative role for the TGFβ accessory receptors TGFβRIII and endoglin. Journal of Cell Communication and Signaling. 5(3). 173–177. 12 indexed citations

Soon, Elaine, Alan Holmes, Carmen Treacy, et al.. (2010). Elevated Levels of Inflammatory Cytokines Predict Survival in Idiopathic and Familial Pulmonary Arterial Hypertension. Circulation. 122(9). 920–927. 588 indexed citations breakdown →

10.

Ponticos, Markella, Alan Holmes, Shiwen Xu, et al.. (2009). Pivotal role of connective tissue growth factor in lung fibrosis: MAPK‐dependent transcriptional activation of type I collagen. Arthritis & Rheumatism. 60(7). 2142–2155. 197 indexed citations

11.

Leask, Andrew, Shiwen Xu, Korsa Khan, et al.. (2008). Loss of protein kinase Cϵ results in impaired cutaneous wound closure and myofibroblast function. Journal of Cell Science. 121(20). 3459–3467. 26 indexed citations

12.

Thomas, Matthew, Alan Holmes, Nicholas Duggan, et al.. (2008). Activin-Like Kinase 5 (ALK5) Mediates Abnormal Proliferation of Vascular Smooth Muscle Cells from Patients with Familial Pulmonary Arterial Hypertension and Is Involved in the Progression of Experimental Pulmonary Arterial Hypertension Induced by Monocrotaline. American Journal Of Pathology. 174(2). 380–389. 89 indexed citations

13.

Dooley, Audrey, Sylvia Y. Low, Alan Holmes, et al.. (2007). Nitric oxide synthase expression and activity in the tight-skin mouse model of fibrosis. Lara D. Veeken. 47(3). 272–280. 19 indexed citations

14.

Fonseca, Carmen, Gisela Lindahl, Markella Ponticos, et al.. (2007). A Polymorphism in theCTGFPromoter Region Associated with Systemic Sclerosis. New England Journal of Medicine. 357(12). 1210–1220. 152 indexed citations

15.

Holmes, Alan, David Abraham, Youjun Chen, et al.. (2003). Constitutive Connective Tissue Growth Factor Expression in Scleroderma Fibroblasts Is Dependent on Sp1. Journal of Biological Chemistry. 278(43). 41728–41733. 91 indexed citations

16.

Leask, Andrew, Alan Holmes, Carol M. Black, & David Abraham. (2003). Connective Tissue Growth Factor Gene Regulation. Journal of Biological Chemistry. 278(15). 13008–13015. 267 indexed citations

17.

Stratton, Richard, Shiwen Xu, Giorgia Martini, et al.. (2001). Iloprost suppresses connective tissue growth factor production in fibroblasts and in the skin of scleroderma patients. Journal of Clinical Investigation. 108(2). 241–250. 169 indexed citations

18.

Xu, Shiwen, Chris Denton, Alan Holmes, et al.. (1998). Endothelins: Effect on Matrix Biosynthesis and Proliferation in Normal and Scleroderma Fibroblasts. Journal of Cardiovascular Pharmacology. 31. S360–S363. 68 indexed citations

19.

Dzierzak, Elaine, María J. Sánchez, Albrecht Müller, et al.. (1997). Hematopoietic stem cells: Embryonic beginnings. Journal of Cellular Physiology. 173(2). 216–218. 15 indexed citations

20.

Morton, A. Ross, Alan Holmes, & Stephen Waldek. (1986). The kidney in myeloma. BMJ. 292(6516). 339.5–340. 4 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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