A.J. Middleton

914 total citations
25 papers, 659 citations indexed

About

A.J. Middleton is a scholar working on Molecular Biology, Ecology and Oncology. According to data from OpenAlex, A.J. Middleton has authored 25 papers receiving a total of 659 indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Molecular Biology, 7 papers in Ecology and 7 papers in Oncology. Recurrent topics in A.J. Middleton's work include Ubiquitin and proteasome pathways (13 papers), Physiological and biochemical adaptations (7 papers) and Cancer-related Molecular Pathways (7 papers). A.J. Middleton is often cited by papers focused on Ubiquitin and proteasome pathways (13 papers), Physiological and biochemical adaptations (7 papers) and Cancer-related Molecular Pathways (7 papers). A.J. Middleton collaborates with scholars based in New Zealand, Canada and United States. A.J. Middleton's co-authors include Catherine L. Day, Peter L. Davies, Virginia K. Walker, Ido Braslavsky, Peter D. Mace, Melanie M. Tomczak, Robert L. Campbell, Maya Bar Dolev, Christopher B. Marshall and Frédérick Faucher and has published in prestigious journals such as Nature Communications, Journal of Molecular Biology and Biochemistry.

In The Last Decade

A.J. Middleton

24 papers receiving 653 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
A.J. Middleton New Zealand 15 280 268 129 73 65 25 659
Koli Basu United States 9 167 0.6× 174 0.6× 95 0.7× 65 0.9× 40 0.6× 13 430
Andrew J. Scotter Canada 8 213 0.8× 374 1.4× 99 0.8× 161 2.2× 60 0.9× 10 848
Shashikant B. Joshi Singapore 17 409 1.5× 418 1.6× 53 0.4× 69 0.9× 163 2.5× 21 1.1k
Robert Eves Canada 15 105 0.4× 300 1.1× 49 0.4× 87 1.2× 39 0.6× 28 690
Yoshiyuki Nishimiya Japan 22 691 2.5× 255 1.0× 254 2.0× 9 0.1× 127 2.0× 46 1.1k
Heman Chao Canada 16 917 3.3× 347 1.3× 409 3.2× 34 0.5× 305 4.7× 24 1.4k
Carl Jarman United Kingdom 7 139 0.5× 324 1.2× 57 0.4× 7 0.1× 28 0.4× 8 823
Robert P. Evans Canada 11 102 0.4× 94 0.4× 25 0.2× 51 0.7× 36 0.6× 12 334
C L Hew Canada 18 387 1.4× 238 0.9× 66 0.5× 7 0.1× 180 2.8× 30 960
Iryna Kozeretska Ukraine 17 469 1.7× 264 1.0× 149 1.2× 97 1.3× 22 0.3× 97 1.0k

Countries citing papers authored by A.J. Middleton

Since Specialization
Citations

This map shows the geographic impact of A.J. Middleton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by A.J. Middleton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites A.J. Middleton more than expected).

Fields of papers citing papers by A.J. Middleton

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by A.J. Middleton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by A.J. Middleton. The network helps show where A.J. Middleton may publish in the future.

Co-authorship network of co-authors of A.J. Middleton

This figure shows the co-authorship network connecting the top 25 collaborators of A.J. Middleton. A scholar is included among the top collaborators of A.J. Middleton based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with A.J. Middleton. A.J. Middleton is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Middleton, A.J., et al.. (2025). Arkadia and Ark2C Promote Substrate Ubiquitylation with Multiple E2 Enzymes. Journal of Molecular Biology. 437(17). 169259–169259.
2.
Middleton, A.J. & Catherine L. Day. (2023). From seeds to trees: how E2 enzymes grow ubiquitin chains. Biochemical Society Transactions. 51(1). 353–362. 5 indexed citations
3.
Middleton, A.J., et al.. (2023). Zinc finger 1 of the RING E3 ligase, RNF125, interacts with the E2 to enhance ubiquitylation. Structure. 31(10). 1208–1219.e5. 2 indexed citations
4.
Middleton, A.J., et al.. (2022). Ubiquitin and a charged loop regulate the ubiquitin E3 ligase activity of Ark2C. Nature Communications. 13(1). 1181–1181. 15 indexed citations
5.
Middleton, A.J., Joan Teyra, Jingyi Zhu, Sachdev S. Sidhu, & Catherine L. Day. (2021). Identification of Ubiquitin Variants That Inhibit the E2 Ubiquitin Conjugating Enzyme, Ube2k. ACS Chemical Biology. 16(9). 1745–1756. 12 indexed citations
6.
Middleton, A.J., et al.. (2020). The RING Domain of RING Finger 12 Efficiently Builds Degradative Ubiquitin Chains. Journal of Molecular Biology. 432(13). 3790–3801. 15 indexed citations
7.
Bredow, Melissa, Laurie A. Graham, A.J. Middleton, et al.. (2020). Isolation and Characterization of Ice-Binding Proteins from Higher Plants. Methods in molecular biology. 303–332. 2 indexed citations
8.
Middleton, A.J., et al.. (2018). A bidentate Polycomb Repressive-Deubiquitinase complex is required for efficient activity on nucleosomes. Nature Communications. 9(1). 3932–3932. 25 indexed citations
9.
Groves, Matthew R., et al.. (2017). Structural insights into K48-linked ubiquitin chain formation by the Pex4p-Pex22p complex. Biochemical and Biophysical Research Communications. 496(2). 562–567. 4 indexed citations
10.
Middleton, A.J., J. D. Wright, & Catherine L. Day. (2017). Regulation of E2s: A Role for Additional Ubiquitin Binding Sites?. Journal of Molecular Biology. 429(22). 3430–3440. 18 indexed citations
11.
Middleton, A.J., et al.. (2017). The activity of TRAF RING homo- and heterodimers is regulated by zinc finger 1. Nature Communications. 8(1). 1788–1788. 37 indexed citations
12.
Middleton, A.J., et al.. (2016). Structure and Function of the RING Domains of RNF20 and RNF40, Dimeric E3 Ligases that Monoubiquitylate Histone H2B. Journal of Molecular Biology. 428(20). 4073–4086. 23 indexed citations
13.
Middleton, A.J. & Catherine L. Day. (2015). The molecular basis of lysine 48 ubiquitin chain synthesis by Ube2K. Scientific Reports. 5(1). 16793–16793. 46 indexed citations
14.
Middleton, A.J., et al.. (2014). Isolation and Characterization of Ice-Binding Proteins from Higher Plants. Methods in molecular biology. 1166. 255–277. 12 indexed citations
15.
Middleton, A.J., Rhesa Budhidarmo, & Catherine L. Day. (2014). Use of E2~Ubiquitin Conjugates for the Characterization of Ubiquitin Transfer by RING E3 Ligases Such as the Inhibitor of Apoptosis Proteins. Methods in enzymology on CD-ROM/Methods in enzymology. 545. 243–263. 20 indexed citations
16.
Middleton, A.J., Christopher B. Marshall, Frédérick Faucher, et al.. (2012). Antifreeze Protein from Freeze-Tolerant Grass Has a Beta-Roll Fold with an Irregularly Structured Ice-Binding Site. Journal of Molecular Biology. 416(5). 713–724. 105 indexed citations
17.
Lauersen, Kyle J., et al.. (2011). Expression and characterization of an antifreeze protein from the perennial rye grass, Lolium perenne. Cryobiology. 62(3). 194–201. 40 indexed citations
18.
Middleton, A.J., et al.. (2010). Ice restructuring inhibition activities in antifreeze proteins with distinct differences in thermal hysteresis. Cryobiology. 61(3). 327–334. 81 indexed citations
19.
Duivenvoorden, Wilhelmina, A.J. Middleton, & Stephen D. Kinrade. (2008). Divergent effects of orthosilicic acid and dimethylsilanediol on cell survival and adhesion in human osteoblast-like cells. Journal of Trace Elements in Medicine and Biology. 22(3). 215–223. 7 indexed citations
20.
Middleton, A.J., Duncan Cole, & K. D. Macdonald. (1978). A hydroxamic acid from Aspergillus nidulans with antibiotic activity against Proteus species.. The Journal of Antibiotics. 31(11). 1110–1115. 9 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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