Abba E. Leffler

1.2k total citations
15 papers, 841 citations indexed

About

Abba E. Leffler is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Computational Theory and Mathematics. According to data from OpenAlex, Abba E. Leffler has authored 15 papers receiving a total of 841 indexed citations (citations by other indexed papers that have themselves been cited), including 13 papers in Molecular Biology, 3 papers in Cellular and Molecular Neuroscience and 3 papers in Computational Theory and Mathematics. Recurrent topics in Abba E. Leffler's work include Nicotinic Acetylcholine Receptors Study (7 papers), Ion channel regulation and function (5 papers) and Protein Structure and Dynamics (4 papers). Abba E. Leffler is often cited by papers focused on Nicotinic Acetylcholine Receptors Study (7 papers), Ion channel regulation and function (5 papers) and Protein Structure and Dynamics (4 papers). Abba E. Leffler collaborates with scholars based in United States, Germany and Australia. Abba E. Leffler's co-authors include David E. Shaw, Ron O. Dror, Morten Ø. Jensen, Vishwanath Jogini, David W. Borhani, Wendy Lou, Patrick R. Hof, Jeffrey A. Roberts, John H. Morrison and Susan L. Wearne and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Abba E. Leffler

14 papers receiving 836 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Abba E. Leffler United States 8 560 278 139 104 82 15 841
Raymond E. Hulse United States 14 473 0.8× 217 0.8× 71 0.5× 42 0.4× 23 0.3× 16 940
Catherine Van Renterghem France 23 1.8k 3.2× 944 3.4× 267 1.9× 108 1.0× 28 0.3× 39 2.3k
David Naranjo Chile 17 736 1.3× 370 1.3× 235 1.7× 108 1.0× 93 1.1× 31 912
Duk‐Su Koh United States 14 425 0.8× 233 0.8× 60 0.4× 50 0.5× 55 0.7× 21 805
Henry L. Puhl United States 22 1.0k 1.8× 508 1.8× 130 0.9× 67 0.6× 77 0.9× 54 1.6k
Sonja Sučić Austria 23 649 1.2× 582 2.1× 38 0.3× 91 0.9× 15 0.2× 52 1.3k
Mitsuyoshi Toyosato Japan 12 2.6k 4.7× 1.7k 6.1× 95 0.7× 115 1.1× 101 1.2× 14 3.4k
Sujit Kumar Sikdar India 20 596 1.1× 487 1.8× 27 0.2× 36 0.3× 59 0.7× 73 1.2k
Michiko Asai Japan 4 1.3k 2.3× 952 3.4× 34 0.2× 56 0.5× 89 1.1× 4 1.7k
Kimberly A. Clark United States 12 1.0k 1.8× 516 1.9× 454 3.3× 32 0.3× 14 0.2× 18 1.2k

Countries citing papers authored by Abba E. Leffler

Since Specialization
Citations

This map shows the geographic impact of Abba E. Leffler's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Abba E. Leffler with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Abba E. Leffler more than expected).

Fields of papers citing papers by Abba E. Leffler

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Abba E. Leffler. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Abba E. Leffler. The network helps show where Abba E. Leffler may publish in the future.

Co-authorship network of co-authors of Abba E. Leffler

This figure shows the co-authorship network connecting the top 25 collaborators of Abba E. Leffler. A scholar is included among the top collaborators of Abba E. Leffler based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Abba E. Leffler. Abba E. Leffler is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

15 of 15 papers shown
1.
Leffler, Abba E., Evelyne M. Houang, Andrew T. Placzek, et al.. (2025). Exploiting Solvent Exposed Salt-Bridge Interactions for the Discovery of Potent Inhibitors of SOS1 Using Free-Energy Perturbation Simulations. ACS Medicinal Chemistry Letters. 16(3). 444–453. 1 indexed citations
2.
Carney, Daniel W., Michiko Tawada, Jumpei Aida, et al.. (2025). Discovery of Highly Potent Noncovalent Inhibitors of SARS-CoV-2 Main Protease through Computer-Aided Drug Design. Journal of Medicinal Chemistry. 68(20). 21330–21345.
3.
Wang, Hui, Christian Atsriku, Andrew T. Placzek, et al.. (2025). Abstract 4376: Preclinical characterization of SGR-4174, a potent and selective SOS1 inhibitor for the treatment of pan KRAS mutant cancers in combination with KRAS pathway inhibitors. Cancer Research. 85(8_Supplement_1). 4376–4376. 1 indexed citations
4.
Carney, Daniel W., Abba E. Leffler, Jeffrey A. Bell, et al.. (2024). Exploiting high-energy hydration sites for the discovery of potent peptide aldehyde inhibitors of the SARS-CoV-2 main protease with cellular antiviral activity. Bioorganic & Medicinal Chemistry. 103. 117577–117577. 4 indexed citations
5.
Kamnesky, Guy, Jared M. Sampson, Michael Pusch, et al.. (2023). Basic Residues at Position 11 of α-Conotoxin LvIA Influence Subtype Selectivity between α3β2 and α3β4 Nicotinic Receptors via an Electrostatic Mechanism. ACS Chemical Neuroscience. 14(24). 4311–4322. 3 indexed citations
6.
Shan, Yibing, Venkatesh Mysore, Abba E. Leffler, et al.. (2022). How does a small molecule bind at a cryptic binding site?. PLoS Computational Biology. 18(3). e1009817–e1009817. 29 indexed citations
7.
Bos, Pieter H., Evelyne M. Houang, Abba E. Leffler, et al.. (2022). AutoDesigner, a De Novo Design Algorithm for Rapidly Exploring Large Chemical Space for Lead Optimization: Application to the Design and Synthesis of d -Amino Acid Oxidase Inhibitors. Journal of Chemical Information and Modeling. 62(8). 1905–1915. 21 indexed citations
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Sindhikara, Dan, et al.. (2020). Water Thermodynamics of Peptide Toxin Binding Sites on Ion Channels. Toxins. 12(10). 652–652. 3 indexed citations
11.
Wang, Jingyi, Alexander Kuryatov, Abba E. Leffler, et al.. (2019). Discovery of an intrasubunit nicotinic acetylcholine receptor–binding site for the positive allosteric modulator Br-PBTC. Journal of Biological Chemistry. 294(32). 12132–12145. 7 indexed citations
12.
Leffler, Abba E., Alexander Kuryatov, Henry Zebroski, et al.. (2017). Discovery of peptide ligands through docking and virtual screening at nicotinic acetylcholine receptor homology models. Proceedings of the National Academy of Sciences. 114(38). E8100–E8109. 51 indexed citations
13.
Verdes, Aída, Prachi Anand, Stephen A. Jannetti, et al.. (2016). From Mollusks to Medicine: A Venomics Approach for the Discovery and Characterization of Therapeutics from Terebridae Peptide Toxins. Toxins. 8(4). 117–117. 33 indexed citations
14.
Jensen, Morten Ø., Vishwanath Jogini, David W. Borhani, et al.. (2012). Mechanism of Voltage Gating in Potassium Channels. Science. 336(6078). 229–233. 458 indexed citations
15.
Hao, Jiandong, Peter R. Rapp, Abba E. Leffler, et al.. (2006). Estrogen Alters Spine Number and Morphology in Prefrontal Cortex of Aged Female Rhesus Monkeys. Journal of Neuroscience. 26(9). 2571–2578. 209 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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