Aarnoud C. van der Spoel

2.6k total citations · 1 hit paper
27 papers, 2.1k citations indexed

About

Aarnoud C. van der Spoel is a scholar working on Physiology, Molecular Biology and Cell Biology. According to data from OpenAlex, Aarnoud C. van der Spoel has authored 27 papers receiving a total of 2.1k indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Physiology, 13 papers in Molecular Biology and 8 papers in Cell Biology. Recurrent topics in Aarnoud C. van der Spoel's work include Lysosomal Storage Disorders Research (17 papers), Cellular transport and secretion (7 papers) and Sphingolipid Metabolism and Signaling (6 papers). Aarnoud C. van der Spoel is often cited by papers focused on Lysosomal Storage Disorders Research (17 papers), Cellular transport and secretion (7 papers) and Sphingolipid Metabolism and Signaling (6 papers). Aarnoud C. van der Spoel collaborates with scholars based in United Kingdom, United States and Canada. Aarnoud C. van der Spoel's co-authors include Frances M. Platt, Barry Boland, Alessandra d’Azzo, Erik Bonten, Maarten Fornerod, Gerard C. Grosveld, Terry D. Butters, Raymond A. Dwek, Chia‐Chen Chuang and David A. Priestman and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Aarnoud C. van der Spoel

27 papers receiving 2.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Lysosomal storage disorders: The cellular impact of lysosomal dysfunction

2012 530 citations Frances M. Platt, Aarnoud C. van der Spoel et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Aarnoud C. van der Spoel United Kingdom	18	1.1k	932	700	352	258	27	2.1k
Rodney E. Infante United States	17	946 0.9×	1.1k 1.2×	542 0.8×	312 0.9×	247 1.0×	30	2.2k
Klaus Ferlinz Germany	26	1.9k 1.8×	1.1k 1.2×	512 0.7×	159 0.5×	191 0.7×	31	2.6k
Paola Di Natale Italy	25	564 0.5×	1.3k 1.3×	438 0.6×	683 1.9×	308 1.2×	90	1.8k
Ida Annunziata United States	22	1.1k 1.0×	865 0.9×	613 0.9×	568 1.6×	160 0.6×	42	2.1k
Alfonso González‐Noriega Mexico	13	790 0.7×	416 0.4×	500 0.7×	106 0.3×	179 0.7×	28	1.3k
Flora Guerra Italy	25	1.4k 1.3×	299 0.3×	277 0.4×	402 1.1×	34 0.1×	57	2.3k
Elvira Costantino‐Ceccarini Italy	22	706 0.7×	519 0.6×	195 0.3×	118 0.3×	134 0.5×	45	1.3k
J. A. Lowden Canada	25	1.2k 1.2×	1.3k 1.4×	418 0.6×	301 0.9×	488 1.9×	77	2.3k
Torben Lübke Germany	22	985 0.9×	734 0.8×	612 0.9×	276 0.8×	299 1.2×	44	1.9k
Lina Abi-Mosleh United States	9	800 0.7×	876 0.9×	402 0.6×	235 0.7×	220 0.9×	9	1.7k

Countries citing papers authored by Aarnoud C. van der Spoel

Since Specialization

Citations

This map shows the geographic impact of Aarnoud C. van der Spoel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Aarnoud C. van der Spoel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Aarnoud C. van der Spoel more than expected).

Fields of papers citing papers by Aarnoud C. van der Spoel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Aarnoud C. van der Spoel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Aarnoud C. van der Spoel. The network helps show where Aarnoud C. van der Spoel may publish in the future.

Co-authorship network of co-authors of Aarnoud C. van der Spoel

This figure shows the co-authorship network connecting the top 25 collaborators of Aarnoud C. van der Spoel. A scholar is included among the top collaborators of Aarnoud C. van der Spoel based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Aarnoud C. van der Spoel. Aarnoud C. van der Spoel is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Ostermeyer‐Fay, Anne G., Abhay Kanodia, María José Hernandez‐Corbacho, et al.. (2024). The steady-state level of plasma membrane ceramide is regulated by neutral sphingomyelinase 2. Journal of Lipid Research. 66(1). 100719–100719. 3 indexed citations

Spoel, Aarnoud C. van der, et al.. (2020). Truncated mutants of beta-glucosidase 2 (GBA2) are localized in the mitochondrial matrix and cause mitochondrial fragmentation. PLoS ONE. 15(6). e0233856–e0233856. 6 indexed citations

Huebecker, Mylene, Elizabeth B. Moloney, Aarnoud C. van der Spoel, et al.. (2019). Reduced sphingolipid hydrolase activities, substrate accumulation and ganglioside decline in Parkinson’s disease. Molecular Neurodegeneration. 14(1). 40–40. 126 indexed citations

Zhao, Kexin, Aarnoud C. van der Spoel, Claudia Castiglioni, et al.. (2018). 19q13.12 microdeletion syndrome fibroblasts display abnormal storage of cholesterol and sphingolipids in the endo-lysosomal system. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1864(6). 2108–2118. 2 indexed citations

Veinotte, Chansey J., et al.. (2016). Characterization of the Zebrafish Homolog of β-Glucosidase 2: A Target of the Drug Miglustat. Zebrafish. 13(3). 177–187. 9 indexed citations

Reichbauer, Jennifer, et al.. (2015). Lack of enzyme activity in GBA2 mutants associated with hereditary spastic paraplegia/cerebellar ataxia (SPG46). Biochemical and Biophysical Research Communications. 465(1). 35–40. 31 indexed citations

Priestman, David A., et al.. (2015). Verification and refinement of cellular glycosphingolipid profiles using HPLC. Biochemistry and Cell Biology. 93(6). 581–586. 4 indexed citations

Barry, Conor S., Holger Kramer, Chia‐Chen Chuang, et al.. (2013). Glycomimetic affinity-enrichment proteomics identifies partners for a clinically-utilized iminosugar. Chemical Science. 4(9). 3442–3442. 6 indexed citations

Thillaiappan, Nagendra Babu, et al.. (2013). β-Glucosidase 2 (GBA2) Activity and Imino Sugar Pharmacology. Journal of Biological Chemistry. 288(36). 26052–26066. 68 indexed citations

10.

Oko, Richard, et al.. (2011). Fusion failure of dense-cored proacrosomal vesicles in an inducible mouse model of male infertility. Cell and Tissue Research. 346(1). 119–134. 12 indexed citations

11.

Speak, Anneliese O., Emyr Lloyd‐Evans, David A. Smith, et al.. (2008). Beneficial effects of substrate reduction therapy in a mouse model of GM1 gangliosidosis. Molecular Genetics and Metabolism. 94(2). 204–211. 62 indexed citations

12.

D’Angelo, Giovanni, Elena Polishchuk, Giuseppe Di Tullio, et al.. (2007). Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide. Nature. 449(7158). 62–67. 336 indexed citations

13.

Wu, Alexander T.H., Peter Šutovský, Wei Xu, et al.. (2007). The postacrosomal assembly of sperm head protein, PAWP, is independent of acrosome formation and dependent on microtubular manchette transport. Developmental Biology. 312(2). 471–483. 51 indexed citations

14.

Bone, Wilhelm, Martin Fritsch, Ulrike Voigtmann, et al.. (2007). The sensitivity of murine spermiogenesis to miglustat is a quantitative trait: a pharmacogenetic study. Reproductive Biology and Endocrinology. 5(1). 1–1. 55 indexed citations

15.

Priestman, David A., Aarnoud C. van der Spoel, Terry D. Butters, Raymond A. Dwek, & Frances M. Platt. (2007). N ‐butyldeoxynojirimycin causes weight loss as a result of appetite suppression in lean and obese mice. Diabetes Obesity and Metabolism. 10(2). 159–166. 23 indexed citations

16.

Sandhoff, Roger, Chia‐Chen Chuang, Yildiz Yildiz, et al.. (2007). Accumulation of Glucosylceramide in Murine Testis, Caused by Inhibition of β-Glucosidase 2. Journal of Biological Chemistry. 282(45). 32655–32664. 63 indexed citations

17.

Butters, Terry D., et al.. (2006). Long-term non-hormonal male contraception in mice using N-butyldeoxynojirimycin. Human Reproduction. 21(5). 1309–1315. 24 indexed citations

18.

Suganuma, Ryota, Terry D. Butters, Frances M. Platt, et al.. (2004). Alkylated Imino Sugars, Reversible Male Infertility-Inducing Agents, Do Not Affect the Genetic Integrity of Male Mouse Germ Cells During Short-Term Treatment Despite Induction of Sperm Deformities1. Biology of Reproduction. 72(4). 805–813. 48 indexed citations

19.

Spoel, Aarnoud C. van der, Mylvaganam Jeyakumar, Terry D. Butters, et al.. (2002). Reversible infertility in male mice after oral administration of alkylated imino sugars: A nonhormonal approach to male contraception. Proceedings of the National Academy of Sciences. 99(26). 17173–17178. 87 indexed citations

20.

Joziasse, David H., et al.. (1990). α1 → 3‐Galactosyltransferase: the use of recombinant enzyme for the synthesis of α‐galactosylated glycoconjugates. European Journal of Biochemistry. 191(1). 75–83. 53 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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