Standout Papers

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in <i>Tlr4</i> Gene 1998 2026 2007 2016 6.2k
  1. Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene (1998)
    Alexander Poltorak, Xiaolong He et al. Science
  2. Identification of Lps2 as a key transducer of MyD88-independent TIR signalling (2003)
    Kasper Hoebe, Xin Du et al. Nature
  3. Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection (2004)
    Koichi Tabeta, Philippe Georgel et al. Proceedings of the National Academy of Sciences
  4. CD36 is a sensor of diacylglycerides (2005)
    Kasper Hoebe, Philippe Georgel et al. Nature
  5. GENETIC ANALYSIS OF HOST RESISTANCE: Toll-Like Receptor Signaling and Immunity at Large (2006)
    Bruce Beutler, Zhengfan Jiang et al. Annual Review of Immunology
  6. The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9 (2006)
    Koichi Tabeta, Kasper Hoebe et al. Nature Immunology
  7. CD14 is required for MyD88-independent LPS signaling (2005)
    Zhengfan Jiang, Philippe Georgel et al. Nature Immunology
  8. CD44 Is the Signaling Component of the Macrophage Migration Inhibitory Factor-CD74 Receptor Complex (2006)
    Lin Leng, Tian Wang et al. Immunity
  9. How we detect microbes and respond to them: the Toll-like receptors and their transducers (2003)
    Bruce Beutler, Kasper Hoebe et al. Journal of Leukocyte Biology
  10. The Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency (2008)
    Xin Du, Terri Gelbart et al. Science
  11. Three novel mammalian toll-like receptors: gene structure, expression, and evolution. (2000)
    Xin Du, Alexander Poltorak et al. PubMed
  12. Genetic and Physical Mapping of theLpsLocus: Identification of the Toll-4 Receptor as a Candidate Gene in the Critical Region (1998)
    Alexander Poltorak, Irina Smirnova et al. Blood Cells Molecules and Diseases

Immediate Impact

70 by Nobel laureates 110 from Science/Nature 331 standout
Sub-graph 1 of 10

Citing Papers

A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
The maternal microbiota drives early postnatal innate immune development
2016 StandoutScience
2 intermediate papers

Works of Xin Du being referenced

MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands
2010 Nobel
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
2003 StandoutNatureNobel
and 1 more

Author Peers

Author Last Decade Papers Cites
Xin Du 11227 3612 1707 2597 91 16.1k
Marina A. Freudenberg 12809 5032 1647 3629 170 20.6k
Paul J. Godowski 9693 6573 2059 2983 64 18.4k
Steven Dower 10589 5460 1943 1917 189 17.3k
R. Alan B. Ezekowitz 10386 4599 476 2329 136 17.5k
John C. Mathison 7040 3430 901 2075 67 11.4k
Lena Alexopoulou 13048 3774 1359 3668 76 17.7k
Makoto Matsumoto 10051 5638 1496 2933 170 17.7k
Jie‐Oh Lee 5433 5482 1012 1559 79 12.0k
Kensuke Miyake 15688 7046 2453 3986 215 23.5k
Brian G. Monks 8420 6880 1609 2111 52 13.9k

All Works

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2026