Citation Impact

Citing Papers

Expanded therapeutic potential in activity space of next-generation 5-nitroimidazole antimicrobials with broad structural diversity
2013 StandoutNobel
Reactive Oxygen Species in Inflammation and Tissue Injury
2013 Standout
Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function
2009
Properties of the Permeability Transition Pore in Mitochondria Devoid of Cyclophilin D
2005
β-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation
2009 StandoutNobel
Human induced pluripotent stem cells and their use in drug discovery for toxicity testing
2013
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
2010 Standout
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
Autophagy and the Integrated Stress Response
2010 Standout
mRNA-based therapeutics — developing a new class of drugs
2014 StandoutNobel
Instructive Roles of Extracellular Matrix on Autophagy
2014
Autophagy in mammalian development and differentiation
2010 Standout
The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease
2015 Standout
Marine natural products
1990 Standout
Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
2008 Standout
Collagen VI related muscle disorders
2005
Hallmarks of aging: An expanding universe
2023 Standout
Mitochondrial permeability transition in Ca2+-dependent apoptosis and necrosis
2011
ChEMBL: a large-scale bioactivity database for drug discovery
2011 Standout
Correlated three-dimensional light and electron microscopy reveals transformation of mitochondria during apoptosis
2007
Lipid Infusion Decreases the Expression of Nuclear Encoded Mitochondrial Genes and Increases the Expression of Extracellular Matrix Genes in Human Skeletal Muscle
2004
Machine learning for molecular and materials science
2018 StandoutNature
Tumor Cell Metabolism: Cancer's Achilles' Heel
2008 Standout
Mitochondrial fusion and fission in cell life and death
2010 Standout
Collagen VI is a basement membrane component that regulates epithelial cell–fibronectin interactions
2011
Autophagy: Renovation of Cells and Tissues
2011 Standout
Mitochondria: In Sickness and in Health
2012 Standout
Molecular mechanisms of cisplatin resistance
2011 Standout
Bcl-2 and Ca2+ homeostasis in the endoplasmic reticulum
2006
Mitochondrial pharmacology
2012
Extracellular matrix structure
2015 Standout
Roles of TRPM2 in oxidative stress
2011
Molecular Mechanisms of Stress-Responsive Changes in Collagen and Elastin Networks in Skin
2016 Standout
Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
2010 Standout
The mitochondrial permeability transition fromin vitroartifact to disease target
2006
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
2010 Standout
Microfluidic organs-on-chips
2014 Standout
Modulation of the mitochondrial permeability transition by cyclophilin D: Moving closer to F0–F1 ATP synthase?
2011
Remodelling the extracellular matrix in development and disease
2014 Standout
Self-consumption: the interplay of autophagy and apoptosis
2014 Standout
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Three Novel Collagen VI Chains, α4(VI), α5(VI), and α6(VI)
2008
Yessotoxin, a shellfish biotoxin, is a potent inducer of the permeability transition in isolated mitochondria and intact cells
2004
Autophagy and Aging
2011 Standout
Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection of human hepatotoxins
2012
Mitochondrial Pathway Is Responsible for Aging-Related Increase of Tubular Cell Apoptosis in Renal Ischemia/Reperfusion Injury
2005
Autophagy is defective in collagen VI muscular dystrophies, and its reactivation rescues myofiber degeneration
2010
Molecular mechanisms of necroptosis: an ordered cellular explosion
2010 Standout
Insights into the key roles of proteoglycans in breast cancer biology and translational medicine
2015
The ChEMBL database in 2017
2016 Standout
Self-eating and self-killing: crosstalk between autophagy and apoptosis
2007 Standout
Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities
2008 Standout
Thousands of chemical starting points for antimalarial lead identification
2010 Nature
Mitochondria as multifaceted regulators of cell death
2019 Standout
Early versus Late Parenteral Nutrition in Critically Ill Adults
2011 Standout
The Hallmarks of Aging
2013 Standout
Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens
2015 StandoutNobel
Mitochondrial Ca2+ influx and efflux rates in guinea pig cardiac mitochondria:Low and high affinity effects of cyclosporine A
2011
The Mitochondrial Effects of Small Organic Ligands of BCL-2
2006
The BCL-2 protein family: opposing activities that mediate cell death
2007 Standout
Mitochondrial Rhomboid PARL Regulates Cytochrome c Release during Apoptosis via OPA1-Dependent Cristae Remodeling
2006
Mitochondria and cancer
2012 Standout
Cellular Imaging Predictions of Clinical Drug-Induced Liver Injury
2008
Microengineered Liver Tissues for Drug Testing
2015
AMP-activated protein kinase at the nexus of therapeutic skeletal muscle plasticity in Duchenne muscular dystrophy
2013
Mitochondria and cell death: outer membrane permeabilization and beyond
2010 Standout
Genetic diseases of connective tissues: cellular and extracellular effects of ECM mutations
2009
Autophagy Is Required to Maintain Muscle Mass
2009
Use of Micropatterned Cocultures to Detect Compounds That Cause Drug-Induced Liver Injury in Humans
2012
From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus
2009 Standout
EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals
2015 Standout
pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures
2015 Standout
Control of inositol 1,4,5-trisphosphate-induced Ca2+ release by cytosolic Ca2+
1995 Standout
Update on EPA’s ToxCast Program: Providing High Throughput Decision Support Tools for Chemical Risk Management
2012
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
2014 Standout
Mitochondrial Fission, Fusion, and Stress
2012 StandoutScience
The Liver Toxicity Knowledge Base (LKTB) and drug-induced liver injury (DILI) classification for assessment of human liver injury
2017
Collagen Structure and Stability
2009 Standout
ProTox-II: a webserver for the prediction of toxicity of chemicals
2018 Standout
Spermidine in health and disease
2018 StandoutScience
Stochastic non-enzymatic modification of long-lived macromolecules - A missing hallmark of aging
2020
High-Content Screening as a Universal Tool for Fingerprinting of Cytotoxicity of Nanoparticles
2008
Mitochondria as Functional Targets of Proteins Coded by Human Tumor Viruses
2005
Negligible Particle-Specific Antibacterial Activity of Silver Nanoparticles
2012 Standout
Trust, But Verify: On the Importance of Chemical Structure Curation in Cheminformatics and QSAR Modeling Research
2010
Reactivation of autophagy by spermidine ameliorates the myopathic defects of collagen VI-null mice
2015
Cheminformatics Analysis of Assertions Mined from Literature That Describe Drug-Induced Liver Injury in Different Species
2009
Mitochondrial Energetics and Therapeutics
2010

Works of William Irwin being referenced

Mitochondrial dysfunction and apoptosis in myopathic mice with collagen VI deficiency
2003
Inhibition of the Mitochondrial Permeability Transition by Aldehydes
2002
Bupivacaine Myotoxicity Is Mediated by Mitochondria
2002
High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening
2006
Early resistance to cell death and to onset of the mitochondrial permeability transition during hepatocarcinogenesis with 2-acetylaminofluorene
2003
Rankless by CCL
2026