Standout Papers

Appearance of Water Chann... 1992 2026 2003 2014 1992 1992 2000 1994 1995 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation benchmark for papers published in the same subfield and year, or reaches the top citation threshold in at least one of its specific research topics.

  1. Appearance of Water Channels in Xenopus Oocytes Expressing Red Cell CHIP28 Protein
    1992 1.6k citations Gregory M. Preston, Tiziana Piazza Carroll et al. Science profile →
  2. In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium
    1992 774 citations Melissa A. Rosenfeld, Kunihiko Yoshimura et al. Cell profile →
  3. Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents
    2000 659 citations Kazushige Hanaoka, Feng Qian et al. Nature profile →
  4. Molecular characterization of an aquaporin cDNA from brain: candidate osmoreceptor and regulator of water balance.
    1994 586 citations Jin Sup Jung, Ratan V. Bhat et al. Proceedings of the National Academy of Sciences profile →
  5. CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP
    1995 548 citations Erik M. Schwiebert, Marie E. Egan et al. Cell profile →
  6. Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout
    2009 494 citations Owen M. Woodward, Anna Köttgen et al. Proceedings of the National Academy of Sciences profile →
  7. Molecular structure of the water channel through aquaporin CHIP. The hourglass model.
    1994 493 citations Jin Sup Jung, Gregory M. Preston et al. Journal of Biological Chemistry profile →
  8. From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations
    2016 415 citations Guido Veit, Radu G. Avramescu et al. Molecular Biology of the Cell profile →
  9. Molecular Cloning and Characterization of an Aquaporin cDNA from Salivary, Lacrimal, and Respiratory Tissues
    1995 360 citations Surabhi Raina, Gregory M. Preston et al. Journal of Biological Chemistry profile →

Immediate Impact

130 by Nobel laureates 74 from Science/Nature 106 hit
Sub-graph 1 of 13

Citing Papers

Maximizing the right stuff: The trade-off between membrane permeability and selectivity
2017 HitScience
In vivo aspects of protein folding and quality control
2016 HitScience
1 intermediate paper

Works of William B. Guggino being referenced

From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations
2016 Hit
Structure and Dynamics of NBD1 from CFTR Characterized Using Crystallography and Hydrogen/Deuterium Exchange Mass Spectrometry
2009
and 2 more

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author Last Decade Papers Cites
William B. Guggino 13.5k 7.4k 4.6k 2.3k 1.6k 248 22.4k
Nobuyoshi Shimizu 12.5k 0.9× 4.0k 0.5× 5.2k 1.1× 3.5k 1.5× 1.8k 1.1× 541 27.5k
Chawnshang Chang 15.1k 1.1× 9.9k 1.3× 7.1k 1.5× 2.0k 0.9× 912 0.6× 446 29.3k
Johanna M. Rommens 9.0k 0.7× 12.7k 1.7× 5.3k 1.1× 941 0.4× 1.3k 0.8× 132 25.0k
Marco E. Bianchi 13.1k 1.0× 1.9k 0.3× 2.9k 0.6× 1.1k 0.5× 1.6k 1.0× 225 30.9k
John F. Engelhardt 11.1k 0.8× 5.2k 0.7× 7.4k 1.6× 595 0.3× 1.7k 1.1× 313 21.5k
Beverly H. Koller 9.4k 0.7× 2.6k 0.3× 3.4k 0.7× 1.9k 0.8× 2.5k 1.6× 205 25.1k
Dennis Brown 15.8k 1.2× 4.1k 0.5× 1.3k 0.3× 959 0.4× 2.3k 1.4× 366 23.3k
Min Lü 13.1k 1.0× 2.7k 0.4× 2.6k 0.6× 1.1k 0.5× 2.1k 1.3× 227 21.3k
Anton M. Jetten 9.0k 0.7× 1.8k 0.2× 3.7k 0.8× 1.1k 0.5× 1.7k 1.1× 333 21.9k
Francesco J. DeMayo 14.7k 1.1× 3.0k 0.4× 8.5k 1.8× 1.3k 0.6× 1.4k 0.9× 401 32.2k

All Works

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Rankless by CCL
2026