Standout Papers
Citation Impact
Citing Papers
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin
2012 Standout
Imbalance of a serotonergic system in frontotemporal dementia: implication for pharmacotherapy
2007
Mitigating risk in academic preclinical drug discovery
2015
A cell-free platform for the prenylation of natural products and application to cannabinoid production
2019 StandoutNobel
“On Water”: Unique Reactivity of Organic Compounds in Aqueous Suspension
2005 StandoutNobel
Asymmetric synthesis of tertiary thiols and thioethers
2011
A view on drug resistance in cancer
2019 StandoutNature
Total Synthesis of Antascomicin B
2005
Dynamic Covalent Chemistry
2002 StandoutNobel
Protecting‐Group‐Free Total Synthesis of (−)‐Rhazinilam and (−)‐Rhazinicine using a Gold‐Catalyzed Cascade Cyclization
2013
Asymmetric Synthesis of β‐Alkynyl Aldehydes by Rhodium‐Catalyzed Conjugate Alkynylation
2009
Amyotrophic lateral sclerosis
2011 Standout
Enantioselective Synthesis of Tertiary and Quaternary Stereogenic Centers: Copper/Phosphoramidite‐Catalyzed Allylic Alkylation with Organolithium Reagents
2012 StandoutNobel
Widely Applicable Pd‐Catalyzed trans‐Selective Monoalkylation of Unactivated 1,1‐Dichloro‐1‐alkenes and Pd‐Catalyzed Second Substitution for the Selective Synthesis of E or Z Trisubstituted Alkenes
2005 StandoutNobel
Total Synthesis of Platencin
2008
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Total Synthesis and Structural Elucidation of (−)‐Delactonmycin
2003
Stereospecific and Stereodivergent Construction of Tertiary and Quaternary Carbon Centers through Switchable Directed/Nondirected Allylic Substitution
2006
A Bioorthogonal Reaction of N‐Oxide and Boron Reagents
2015 StandoutNobel
The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: the CD-spiroacetal segment
2005
Synthetic lethal therapies for cancer: what’s next after PARP inhibitors?
2018
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
2017 Standout
Enantioselective Synthesis of (−)‐Exiguolide by Iterative Stereoselective Dioxinone‐Directed Prins Cyclizations
2011
The PI3K Pathway in Human Disease
2017 Standout
The Organocatalytic Asymmetric Prins Cyclization
2015 StandoutNobel
Theoretical studies on the mechanism of conversion of androgens to estrogens by aromatase
1991
Design and Synthesis of a Novel Class of Constrained Tricyclic Pyrrolizidinone Carboxylic Acids as Carbapenem Mimics
2002
Iron Catalysis in Organic Synthesis
2015 Standout
Ligand-Gated Ion Channels: New Insights into Neurological Disorders and Ligand Recognition
2012
CuO and Ag2O/CuO Catalyzed Oxidation of Aldehydes to the Corresponding Carboxylic Acids by Molecular Oxygen
2008
‘Slow-binding’ sixth-ligand inhibitors of cytochrome P-450 aromatase. Studies with 19-thiomethyl- and 19-azido-androstenedione
1991
Toluene Dioxygenase-Mediated cis-Dihydroxylation of Aromatics in Enantioselective Synthesis. Asymmetric Total Syntheses of Pancratistatin and 7-Deoxypancratistatin, Promising Antitumor Agents1
1996
Chemistry of Polyvalent Iodine
2008 Standout
Natural Product Synthesis Using Multicomponent Reaction Strategies
2009 Standout
Copper-Catalyzed Regio- and Enantioselective Synthesis of Chiral Enol Acetates and β-Substituted Aldehydes
2010 StandoutNobel
A convenient synthesis of aziridine‐2‐carboxylic esters
1992
A General Catalytic Asymmetric Prins Cyclization
2016 StandoutNobel
Der Mechanismus der Claisen‐Umlagerung – ein Déjà‐vu
1996
Chemical Conversion of Linkages in Covalent Organic Frameworks
2016 StandoutNobel
Synthesis of Pyridine and Dihydropyridine Derivatives by Regio- and Stereoselective Addition toN-Activated Pyridines
2012 Standout
Protecting group free enantiospecific total syntheses of structurally diverse natural products of the tetrahydrocannabinoid family
2015
Advances in Transition Metal (Pd,Ni,Fe)-Catalyzed Cross-Coupling Reactions Using Alkyl-organometallics as Reaction Partners
2011 Standout
Catalytic Enantioselective Conversion of Epoxides to Thiiranes
2016 StandoutNobel
Chiral Aminophosphines as Catalysts for Enantioselective Double-Michael Indoline Syntheses
2012
Aromatase Inhibitors in the Treatment of Breast Cancer
2005
Phosphine Organocatalysis
2018 Standout
Bright Side of Lignin Depolymerization: Toward New Platform Chemicals
2018 Standout
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Highly Stereo- and Regioselective Synthesis of (Z)-Trisubstituted Alkenes via 1-Bromo-1-alkyne Hydroboration−Migratory Insertion−Zn-Promoted Iodinolysis and Pd-Catalyzed Organozinc Cross-Coupling
2007 StandoutNobel
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Use of Lawesson's Reagent in Organic Syntheses
2007 Standout
Stereoselective synthesis of α-hydroxy-β-amino acid derivatives from β-hydroxy-γ,δ-unsaturated sulfilimine
2008
Cascade Processes of Metallo Carbenoids
1996 Standout
An Efficient and Mild Direct Oxidative Methyl Esterification of Aromatic Aldehydes Using NaBr and Diacetoxyiodobenzene
2005
Stereoselective Cyclopropanation Reactions
2003 Standout
Oxidation of 2-substituted allylsilane to conjugated enal using hypervalent organoiodine compound and synthesis of α-methylen γ-and δ-lactones
1983
Total Synthesis of (−)-Anisatin
2012
Synthesis of ± 8- and 9-HETEs
1984
Dioxygen Activation at Mononuclear Nonheme Iron Active Sites: Enzymes, Models, and Intermediates
2004 Standout
Organic Polyvalent Iodine Compounds
1996 Standout
The Total Synthesis of (−)-7-Deoxyloganin via N-Heterocyclic Carbene Catalyzed Rearrangement of α,β-Unsaturated Enol Esters
2010
Accessing the amide functionality by the mild and low-cost oxidation of imine
2009
Diastereoselective Allylation of Carbonyl Compounds and Imines: Application to the Synthesis of Natural Products
2013 Standout
Aerobic Copper-Catalyzed Organic Reactions
2013 Standout
Protein-Catalyzed Capture Agents
2019
Recent aspects of thiirane chemistry
1993
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Organocatalytic Reactions Enabled by N-Heterocyclic Carbenes
2015 Standout
Catalytic Asymmetric Conjugate Addition and Allylic Alkylation with Grignard Reagents
2008 StandoutNobel
Organic Reactions in Aqueous Media with a Focus on Carbon−Carbon Bond Formations: A Decade Update
2005 Standout
Activation of C−H Bonds by Metal Complexes
1997 Standout
Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals
2011 Standout
The Mechanism of the Claisen Rearrangement: Déjà Vu All Over Again
1996
Advances in Synthetic Applications of Hypervalent Iodine Compounds
2016 Standout
Reaction of a Cyclic Oxosulfonium Ylide with Acetates of the Baylis-Hillman Adducts: Tandem Michael−Intramolecular Corey-Chaykovsky Reactions
1999
Disulfonimide-Catalyzed Asymmetric Synthesis of β3-Amino Esters Directly from N-Boc-Amino Sulfones
2013 StandoutNobel
Enantioselective Synthesis of (−)‐Exiguolide by Iterative Stereoselective Dioxinone‐Directed Prins Cyclizations
2011
An approach to oxazolidin-2-ones from the Baylis–Hillman adducts. Formal synthesis of a chloramphenicol derivative
2002
Regio- and Stereoselective Synthesis of (E)-Alkene trans-Xaa-Pro Dipeptide Mimetics Utilizing Organocopper-Mediated Anti-SN2‘ Reactions
2002
Leucascandrolide A: A Second Generation Formal Synthesis
2003
Emerging Targets in Photopharmacology
2016 StandoutNobel
More than Restriction of Twisted Intramolecular Charge Transfer: Three-Dimensional Expanded #-Shaped Cross-Molecular Packing for Emission Enhancement in Aggregates
2012
Total synthesis of pyripyropene A
2011 StandoutNobel
Total Synthesis of (+)-Discodermolide
1998
Structures, Biological Activities, and Total Syntheses of 13-Hydroxy- and 13-Acetoxy-14-nordehydrocacalohastine, Novel Modified Furanoeremophilane-Type Sesquiterpenes from Trichilia cuneata
2005
A novel expeditious entry into gibberellins. The total synthesis of (±)-GA5
1986
Toward the total synthesis of Luminamicin: construction of 14-membered lactone framework possessing versatile enol ether moiety
2012 StandoutNobel
Recent Advances in the Baylis−Hillman Reaction and Applications
2003 Standout
Total Syntheses of Amphidinolide X and Y
2006
Synthesis of 6α,7α- and 6β,7β-aziridinoandrost-4-ene-3,17-diones and related compounds: potential aromatase inhibitors
1995
Synthesis of Zaragozic Acid A/Squalestatin S1
1995
Catalytic Asymmetric Synthesis of Thiols
2014 StandoutNobel
Catalytic Asymmetric Vinylogous Prins Cyclization: A Highly Diastereo- and Enantioselective Entry to Tetrahydrofurans
2016 StandoutNobel
Gold(I)-Catalyzed Activation of Alkynes for the Construction of Molecular Complexity
2015 Standout
Catalyst Control in Sequential Asymmetric Allylic Substitution: Stereodivergent Access to N,N-Diprotected Unnatural Amino Acids
2011
Regio and enantioselective synthesis of 4-carbomethoxymethyl-1,4 dihydropyridines
1994
The synthesis of 14-membered macrocyclic ethers
1999
Works of Wayne E. Childers being referenced
Resistance to BET Bromodomain Inhibitors Is Mediated by Kinome Reprogramming in Ovarian Cancer
2016
Lecozotan (SRA-333): A Selective Serotonin 1A Receptor Antagonist That Enhances the Stimulated Release of Glutamate and Acetylcholine in the Hippocampus and Possesses Cognitive-Enhancing Properties
2005
3,4-Dihydropyrimido(1,2-a)indol-10(2H)-ones as potent non-peptidic inhibitors of caspase-3
2009
Stereoselective inhibition of human placental aromatase
1987
Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profile
2013
Inhibition of aromatase cytochrome P-450 by 10-oxirane and 10-thiirane substituted androgens. Implications for the structure of the active site.
1987
Synthesis and SAR of Adatanserin: Novel Adamantyl Aryl- and Heteroarylpiperazines with Dual Serotonin 5-HT1A and 5-HT2 Activity as Potential Anxiolytic and Antidepressant Agents
1999
Discovery of Innovative Therapeutics: Today’s Realities and Tomorrow’s Vision. 2. Pharma’s Challenges and Their Commitment to Innovation
2014
Oxidation of α,β-un saturated aldehydes
1981 Standout
N-Methyl-d -Aspartate Antagonists and Neuropathic Pain: The Search for Relief
2007
A novel approach to the synthesis of the cannabinoids
1984
Synthesis of 10.beta.-oxiranyl and 10.beta.-thiiranyl steroids
1988
Ribosome-Templated Azide–Alkyne Cycloadditions: Synthesis of Potent Macrolide Antibiotics by In Situ Click Chemistry
2016