Standout Papers
Citation Impact
Citing Papers
Identification of Novel Genes Coding for Small Expressed RNAs
2001 StandoutScience
Species Interactions in a Parasite Community Drive Infection Risk in a Wildlife Population
2010 StandoutScience
Requirement of bic/microRNA-155 for Normal Immune Function
2007 StandoutScience
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Two isoforms of the essential C. elegans Argonaute CSR-1 differentially regulate sperm and oocyte fertility
2021 StandoutNobel
Characterization of a canine homolog of hepatitis C virus
2011 StandoutNobel
Evidence for a functional RNA element in the hepatitis C virus core gene
2007 StandoutNobel
To Interfere and to Anti-interfere: The Interplay Between Hepatitis C Virus and Interferon
2002
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
2001 StandoutNature
Molecular basis of double-stranded RNA-protein interactions: structure of a dsRNA-binding domain complexed with dsRNA
1998
Regulation of microRNA function in animals
2018 Standout
PACT, a protein activator of the interferon-induced protein kinase, PKR
1998
mRNA Is an Endogenous Ligand for Toll-like Receptor 3
2004 StandoutNobel
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
Sirtuin-7 Inhibits the Activity of Hypoxia-inducible Factors
2013 StandoutNobel
The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia
2017 StandoutNobel
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
Cellular autophagy: surrender, avoidance and subversion by microorganisms
2004
Argonaute Proteins: From Structure to Function in Development and Pathological Cell Fate Determination
2020
Autophagy fights disease through cellular self-digestion
2008 StandoutNature
Selection and cloning of poly(rC)-binding protein 2 and Raf kinase inhibitor protein RNA activators of 2′,5′-oligoadenylate synthetase from prostate cancer cells
2006
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
1998 StandoutNatureNobel
Pathogenic roles for Epstein–Barr virus (EBV) gene products in EBV-associated proliferative disorders
2002
The rde-1 Gene, RNA Interference, and Transposon Silencing in C. elegans
1999 StandoutNobel
Characterization of Transgenic Mice with Targeted Disruption of the Catalytic Domain of the Double-stranded RNA-dependent Protein Kinase, PKR
1999
Viral proteins targeting mitochondria: controlling cell death
2004
Molecular Mechanisms of Interferon Resistance Mediated by Viral-Directed Inhibition of PKR, the Interferon-Induced Protein Kinase
1998
A Novel Interaction between Adrenergic Receptors and the α-Subunit of Eukaryotic Initiation Factor 2B
1997 StandoutNobel
Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation
2010 StandoutNobel
The guanine nucleotide-exchange factor, eIF-2B
1994
Transcriptional regulation by hypoxia inducible factors
2013
Regulation of the interferon-induced PKR: can viruses cope?
1995
The Double-Stranded RNA-Dependent Protein Kinase PKR: Structure and Function
1997
Viruses and interferon: a fight for supremacy
2002
Argonaute proteins: functional insights and emerging roles
2013
Oxygen sensing and hypoxia signalling pathways in animals: the implications of physiology for cancer
2013 StandoutNobel
Pseudosubstrate Inhibition of Protein Kinase PKR by Swine Pox Virus C8L Gene Product
2000
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase
1999 StandoutNature
Novel small RNA-encoding genes in the intergenic regions of Escherichia coli
2001
The Flvr-encoded murine oligoadenylate synthetase 1b (Oas1b) suppresses 2-5A synthesis in intact cells
2010
Regulation and Function of the PD-L1 Checkpoint
2018 Standout
Ajuba LIM Proteins Are Snail/Slug Corepressors Required for Neural Crest Development in Xenopus
2008
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
The dsRNA Binding Protein RDE-4 Interacts with RDE-1, DCR-1, and a DExH-Box Helicase to Direct RNAi in C. elegans
2002 StandoutNobel
Characterization of an anti-apoptotic glycoprotein encoded by Kaposi's sarcoma-associated herpesvirus which resembles a spliced variant of human survivin
2002
Detection of genome-scale ordered RNA structure (GORS) in genomes of positive-stranded RNA viruses: Implications for virus evolution and host persistence
2004
FHL family members suppress vascular endothelial growth factor expression through blockade of dimerization of HIF1α and HIF1β
2012
Revealing the world of RNA interference
2004 StandoutNatureNobel
Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways
2016
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
2006 StandoutNature
The Hallmarks of Aging
2013 Standout
The NS5A Protein of Hepatitis C Virus Is a Zinc Metalloprotein
2004 StandoutNobel
A Model for the Double-stranded RNA (dsRNA)-dependent Dimerization and Activation of the dsRNA-activated Protein Kinase PKR
1997
Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling
1998
Argonaute proteins: Structural features, functions and emerging roles
2020
Preferential Translation of Reovirus mRNA by a σ3-Dependent Mechanism
1997
Nucleoside modifications in RNA limit activation of 2'-5'-oligoadenylate synthetase and increase resistance to cleavage by RNase L
2011 StandoutNobel
Site‐Specific Modification of Epstein–Barr Virus‐Encoded RNA 1 with N2‐Benzylguanosine Limits the Binding Sites Occupied by PKR
2004
PKR: a new name and new roles
1995
TMEM41B Is a Pan-flavivirus Host Factor
2020 StandoutNobel
Activation and evasion of the antiviral 2???-5??? oligoadenylate synthetase/ribonuclease L pathway by hepatitis C virus mRNA
2002
Chaperone-mediated Autophagy Targets Hypoxia-inducible Factor-1α (HIF-1α) for Lysosomal Degradation
2013 StandoutNobel
Modeling neurodevelopmental disorder-associated humanAGO1mutations inCaenorhabditis elegansArgonautealg-1
2024 StandoutNobel
Tetrahymena proteins p80 and p95 are not core telomerase components
2001 StandoutNobel
Recognition of Nascent RNA by the Human La Antigen: Conserved and Divergent Features of Structure and Function
2001
Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal
2015 StandoutNobel
The dsRNA binding protein family: critical roles, diverse cellular functions
2003
Identification of Virus-Encoded MicroRNAs
2004 StandoutScience
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression
2014 StandoutNobel
bic, a Novel Gene Activated by Proviral Insertions in Avian Leukosis Virus-Induced Lymphomas, Is Likely To Function through Its Noncoding RNA
1997
ATP-independent diffusion of double-stranded RNA binding proteins
2012 StandoutNobel
Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA
2011 StandoutNobel
Antiviral Actions of Interferons
2001 Standout
A bacterial Argonaute with noncanonical guide RNA specificity
2016 StandoutNobel
EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance
2019 StandoutNobel
Translational Control of Viral Gene Expression in Eukaryotes
2000
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
2001 StandoutNobel
Structural Requirements for Double-Stranded RNA Binding, Dimerization, and Activation of the Human eIF-2α Kinase DAI in Saccharomyces cerevisiae
1995
In vitro activation of the interferon-induced, double-stranded RNA-dependent protein kinase PKR by RNA from the 3' untranslated regions of human alpha-tropomyosin.
1996
Progress in Modeling of Protein Structures and Interactions
2005 StandoutScienceNobel
Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus
2006 StandoutNobel
RNA regulation of the antiviral protein 2′‐5′‐oligoadenylate synthetase
2019
RNA as a target of double-stranded RNA-mediated genetic interference in Caenorhabditis elegans
1998 StandoutNobel
Podocalyxin Increases the Aggressive Phenotype of Breast and Prostate Cancer Cells In vitro through Its Interaction with Ezrin
2007
Mitochondria as Functional Targets of Proteins Coded by Human Tumor Viruses
2005
Poxviruses and Immune Evasion
2003
The γ 1 34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1α to dephosphorylate the α subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-activated protein kinase
1997
Impact of Protein Kinase PKR in Cell Biology: from Antiviral to Antiproliferative Action
2006
Antisense RNA: Function and Fate of Duplex RNA in Cells of Higher Eukaryotes
1998
Human Immunodeficiency Virus Type 1 Vpr Interacts with Antiapoptotic Mitochondrial Protein HAX-1
2005
The Ebola virus VP35 protein functions as a type I IFN antagonist
2000
Autophagy in Health and Disease: A Double-Edged Sword
2004 StandoutScience
Works of Tyson V. Sharp being referenced
Argonaute Utilization for miRNA Silencing Is Determined by Phosphorylation-Dependent Recruitment of LIM-Domain-Containing Proteins
2017
Gene expression array profile of human osteosarcoma
2003
Comparative analysis of the regulation of the interferoninducible protein kinase PKR by Epstein - Barr virus RNAs EBER-1 and EBER-2 and adenovirus VA, RNA
1993
Regulation of the Interferon‐indueible Protein Kinase PKR and (2′‐5′)oligo(Adenylate) Synthetase by a Catalytically Inactive PKR Mutant Through Competition for Double‐stranded RNA Binding
1995
The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity
2012 StandoutNobel
The Vaccinia Virus E3L Gene Product Interacts with both the Regulatory and the Substrate Binding Regions of PKR: Implications for PKR Autoregulation
1998
MicroRNA-155 induction via TNF-α and IFN-γ suppresses expression of programmed death ligand-1 (PD-L1) in human primary cells
2017
Homologous Regions of the α Subunit of Eukaryotic Translational Initiation Factor 2 (eIF2α) and the Vaccinia Virus K3L Gene Product Interact with the Same Domain within the dsRNA‐Activated Protein Kinase (PKR)
1997
Activation of the Interferon-Inducible (2′-5′) Oligoadenylate Synthetase by the Epstein–Barr Virus RNA, EBER-1
1999
Reversal of the double‐stranded‐RNA‐induced inhibition of protein synthesis by a catalytically inactive mutant of the protein kinase PKR
1993
Regulation of the interferon-inducible eIF-2α protein kinase by small RNAs
1994
The La antigen inhibits the activation of the interferoninducible protein kinase PKR by sequestering and unwinding double-stranded RNA
1994
LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing
2010
K15 Protein of Kaposi’s Sarcoma-Associated Herpesvirus Is Latently Expressed and Binds to HAX-1, a Protein with Antiapoptotic Function
2002
LIM domains-containing protein 1 (LIMD1), a tumor suppressor encoded at chromosome 3p21.3, binds pRB and represses E2F-driven transcription
2004