Citation Impact
Citing Papers
Nanog Is the Gateway to the Pluripotent Ground State
2009 StandoutNobel
Structural Basis of Transcription: Role of the Trigger Loop in Substrate Specificity and Catalysis
2006 StandoutNobel
The yeast UASG is a transcriptional enhancer in human hela cells in the presence of the GAL4 trans-activator
1988
T cell exhaustion
2011 Standout
Transcriptional activation by the Antennapedia and fushi tarazu proteins in cultured Drosophila cells
1989
extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing human proto-oncogene pbx1
1993 StandoutNobel
New POU dimer configuration mediates antagonistic control of an osteopontin preimplantation enhancer by Oct-4 and Sox-2
1998
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties
1992 StandoutNobel
Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation
1990 StandoutNatureNobel
CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones
1992 StandoutNatureNobel
Single-Molecule Dynamics of Enhanceosome Assembly in Embryonic Stem Cells
2014 StandoutNobel
The origin of pattern and polarity in the Drosophila embryo
1992 StandoutNobel
Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor
1988
The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein
1991 StandoutNobel
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
IκB: a Specific Inhibitor of the NF-κB Transcription Factor
1988 StandoutScienceNobel
Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor Oct4
1998 Standout
Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence
1989 StandoutNobel
Herpes simplex virus regulatory elements and the immunoglobulin octamer domain bind a common factor and are both targets for virion transactivation
1988
The structure and function of the homeodomain
1989 Standout
The unc-86 gene product couples cell lineage and cell identity in C. elegans
1990 StandoutNobel
The C. elegans cell lineage and differentiation gene unc-86 encodes a protein with a homeodomain and extended similarity to transcription factors
1988 StandoutNobel
Generation of germline-competent induced pluripotent stem cells
2007 StandoutNatureNobel
Molecular cloning of an enhancer binding protein:Isolation by screening of an expression library with a recognition site DNA
1988
POU domain family values: flexibility, partnerships, and developmental codes.
1997
E2F-1 Functions in Mice to Promote Apoptosis and Suppress Proliferation
1996 StandoutNobel
C. elegans unc-4 gene encodes a homeodomain protein that determines the pattern of synaptic input to specific motor neurons
1992 StandoutNatureNobel
Compilation of transcription regulating proteins
1988
Rescue of bicoid mutant Drosophila embryos by Bicoid fusion proteins containing heterologous activating sequences
1989 StandoutNatureNobel
CREB1 Encodes a Nuclear Activator, a Repressor, and a Cytoplasmic Modulator that Form a Regulatory Unit Critical for Long-Term Facilitation
1998 StandoutNobel
C/EBP is an immediate-early gene required for the consolidation of long-term facilitation in Aplysia
1994 StandoutNobel
Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation
1990 StandoutNatureNobel
Homeodomain-DNA recognition
1994 StandoutNobel
Network Analysis Reveals Centrally Connected Genes and Pathways Involved in CD8+ T Cell Exhaustion versus Memory
2012
A gradient of nuclear localization of the dorsal protein determines dorsoventral pattern in the Drosophila embryo
1989 StandoutNobel
A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype
1988
Transcriptional activation by the v-myb oncogene and its cellular progenitor, c-myb
1989 StandoutNobel
The structure of the Antennapedia homeodomain determined by NMR spectroscopy in solution: Comparison with prokaryotic repressors
1989 StandoutNobel
Molecular and cellular insights into T cell exhaustion
2015 Standout
Cyclin A and the retinoblastoma gene product complex with a common transcription factor
1991 StandoutNatureNobel
A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo
1990 Nature
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells
2003 StandoutNobel
Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system
1998 Nature
Human FOXP3+ Regulatory T Cell Heterogeneity and Function in Autoimmunity and Cancer
2019 StandoutNobel
Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB
1988 Nature
New Catalytic System for S−S and Se−Se Bond Addition to Alkynes Based on Phosphite Ligands
2005
Synthesis of Organochalcogen Propargyl Aryl Ethers and Their Application in the Electrophilic Cyclization Reaction: An Efficient Preparation of 3-Halo-4-Chalcogen-2H-Benzopyrans
2009
Multiple mRNA isoforms of the transcription activator protein CREB: generation by alternative splicing and specific expression in primary spermatocytes.
1992
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
B-Cell Control Region at the 5′ End of a Major Histocompatibility Complex Class II Gene: Sequences and Factors
1988
Synthesis of Heterocycles via Electrophilic Cyclization of Alkynes Containing Heteroatom
2011 Standout
Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations.
1992
Rex-1, a Gene Encoding a Transcription Factor Expressed in the Early Embryo, Is Regulated via Oct-3/4 and Oct-6 Binding to an Octamer Site and a Novel Protein, Rox-1, Binding to an Adjacent Site
1998
Systematic Binding Analysis of the Insulin Gene Transcription Control Region: Insulin and Immunoglobulin Enhancers Utilize Similar Transactivators
1988
Synergistic Activation of the Fibroblast Growth Factor 4 Enhancer by Sox2 and Oct-3 Depends on Protein-Protein Interactions Facilitated by a Specific Spatial Arrangement of Factor Binding Sites
1997
Mechanistic study of palladium catalyzed S–S and Se–Se bonds addition to alkynes
2003
Nuclear factor NF-kappa B can interact functionally with its cognate binding site to provide lymphoid-specific promoter function.
1988 Nobel
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
1995 StandoutNobel
Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism
1986 StandoutNobel
Clonal Deletion Versus Clonal Anergy: The Role of the Thymus in Inducing Self Tolerance
1990 StandoutScienceNobel
The Oct-2 protein binds cooperatively to adjacent octamer sites.
1989
Oct-4: a germline-specific transcription factor mapping to the mouse t-complex.
1990
NonO, a non-POU-domain-containing, octamer-binding protein, is the mammalian homolog of Drosophila nonAdiss.
1993
Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase.
1994 Standout
Homeobox genes in normal hematopoiesis and leukemia
1992
Molecular cloning of lymphadenopathy-associated virus
1984 StandoutNatureNobel
Initiation by Yeast RNA Polymerase II at the Adenoviral Major Late Promoter in Vitro
1989 StandoutScienceNobel
Repression of the IgH Enhancer in Teratocarcinoma Cells Associated with a Novel Octamer Factor
1989 ScienceNobel
Deregulation of the ubiquitin system and p53 proteolysis modify the apoptotic response in B-CLL lymphocytes
2000 StandoutNobel
Repair of Cisplatin−DNA Adducts by the Mammalian Excision Nuclease
1996 StandoutNobel
Multicomponent differentiation-regulated transcription factors in F9 embryonal carcinoma stem cells.
1991
Transforming growth factor-beta 1 (TGF-beta1) promotes IL-2 mRNA expression through the up-regulation of NF-kappaB, AP-1 and NF-AT in EL4 cells.
1998
Transition-Metal-Catalyzed C−S, C−Se, and C−Te Bond Formation via Cross-Coupling and Atom-Economic Addition Reactions
2011 Standout
A pituitary POU domain protein, Pit-1, activates both growth hormone and prolactin promoters transcriptionally.
1989
POU-domain proteins Pit-1 and Oct-1 interact to form a heteromeric complex and can cooperate to induce expression of the prolactin promoter.
1991
Activation of Cell-Specific Expression of Rat Growth Hormone and Prolactin Genes by a Common Transcription Factor
1988 Science
Copper-Promoted Carbon−Nitrogen Bond Formation with 2-Iodo-selenophene and Amides
2006
Isolation of a Saccharomyces cerevisiae centromere DNA-binding protein, its human homolog, and its possible role as a transcription factor.
1987 StandoutNobel
Protein-Binding Sites in Ig Gene Enhancers Determine Transcriptional Activity and Inducibility
1987 ScienceNobel
Distinctive Termini Characterize Two Families of Human Endogenous Retroviral Sequences
1984 Science
The B-cell-specific Oct-2 protein contains POU box- and homeo box-type domains.
1988 Nobel
A Cell Culture Model for T Lymphocyte Clonal Anergy
1990 StandoutScience
E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor.
1989
Cooperative Interactions Between the Caenorhabditis elegans Homeoproteins UNC-86 and MEC-3
1993 StandoutScienceNobel
Magnesium-Induced Copper-Catalyzed Synthesis of Unsymmetrical Diaryl Chalcogenide Compounds from Aryl Iodide via Cleavage of the Se−Se or S−S Bond
2004
The Mating of a Fly
1994 StandoutScienceNobel
POU-domain transcription factors: pou-er-ful developmental regulators.
1991
Deregulation of the ubiquitin system and p53 proteolysis modify the apoptotic response in B-CLL lymphocytes
2000 StandoutNobel
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
Alkyl- or Arylthiolation of Aryl Iodide via Cleavage of the S−S Bond of Disulfide Compound by Nickel Catalyst and Zinc
2004
A 100-kD HeLa cell octamer binding protein (OBP100) interacts differently with two separate octamer-related sequences within the SV40 enhancer.
1987
Promoter interaction of the E1A-inducible factor E2F and its potential role in the formation of a multi-component complex.
1987
HNF-1, a member of a novel class of dimerizing homeodomain proteins.
1991
Isolation of a Saccharomyces cerevisiae Centromere DNA-Binding Protein, Its Human Homolog, and its Possible Role as a Transcription Factor
1987 StandoutNobel
De novo design of protein logic gates
2020 StandoutScienceNobel
The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain.
1988
The B cell coactivator Bob1 shows DNA sequence-dependent complex formation with Oct-1/Oct-2 factors, leading to differential promoter activation.
1996
Systematic binding analysis of the insulin gene transcription control region: insulin and immunoglobulin enhancers utilize similar transactivators.
1988
Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3.
1995
Works of Thomas Wirth being referenced
Multiple Oct2 isoforms are generated by alternative splicing
1991
Repetitive Antigen Stimulation Induces Stepwise Transcriptome Diversification but Preserves a Core Signature of Memory CD8+ T Cell Differentiation
2010
Neoantigen Targeting—Dawn of a New Era in Cancer Immunotherapy?
2017
Molecular Principles of Oct2-Mediated Gene Activation in B Cells
1995
The POU domains of the Oct1 and Oct2 transcription factors mediate specific interaction with TBP
1994
Functional Characterization of the Murine Homolog of the B cell-specific Coactivator BOB.1/OBF.1
1995
Organoselenium Chemistry
2000
Inhibition of Nuclear Factor κB Activation Attenuates Apoptosis Resistance in Lymphoid Cells
1998
Differential transactivation potential of Oct1 and Oct2 is determined by additional B cell-specific activities.
1994
Oct2 Transactivation from a Remote Enhancer Position Requires a B-Cell-Restricted Activity
1992
A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes
1986 NatureNobel
Identification of CD36 as the first gene dependent on the B-cell differentiation factor Oct-2.
1995
Family of middle repetitive DNA sequences in the mouse genome with structural features of solitary retroviral long terminal repeats.
1983
High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors.
1995
An octamer oligonucleotide upstream of a TATA motif is sufficient for lymphoid-specific promoter activity
1987 NatureNobel