Citation Impact
Citing Papers
Mammalian Transient Receptor Potential TRPA1 Channels: From Structure to Disease
2019
Multi-target strategies for the improved treatment of depressive states: Conceptual foundations and neuronal substrates, drug discovery and therapeutic application
2006
The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics
2021 Standout
Soft corrugated channel with synergistic exclusive discrimination gating for CO2 recognition in gas mixture
2023 StandoutNobel
Bile acid–microbiota crosstalk in gastrointestinal inflammation and carcinogenesis
2017 Standout
Discovery and evaluation of spirocyclic derivatives as antagonists of the neuropeptide Y5 receptor
2012
Polymer-supported reagents for multi-step organic synthesis: application to the synthesis of sildenafil
2000
The influence of lipophilicity in drug discovery and design
2012
Rethinking amide bond synthesis
2011 StandoutNature
Akkermansia muciniphila and improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology
2015 Standout
From magic bullets to designed multiple ligands
2004
The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of synbiotics
2020 Standout
The role of substance P in stress and anxiety responses
2006
Discovery of spiropiperidine-based potent and selective Orexin-2 receptor antagonists
2011
Irritant-evoked activation and calcium modulation of the TRPA1 receptor
2020 StandoutNatureNobel
Network pharmacology: the next paradigm in drug discovery
2008 Standout
Curcumin as “Curecumin”: From kitchen to clinic
2007 Standout
Cellular and behavioural profile of the novel, selective neurokinin1 receptor antagonist, vestipitant: A comparison to other agents
2008
5-Sulfonyl-benzimidazoles as selective CB2 agonists-Part 2
2011
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
2013 Standout
The Endocannabinoid System as an Emerging Target of Pharmacotherapy
2006 Standout
New approaches to antidepressant drug discovery: beyond monoamines
2006
Brain correlates of music-evoked emotions
2014 Standout
Pharmaceutical and medicinal significance of sulfur (SVI)-Containing motifs for drug discovery: A critical review
2018 Standout
Small-Molecule Library Screening by Docking with PyRx
2014 Standout
Carbazole-containing sulfonamides and sulfamides: Discovery of cryptochrome modulators as antidiabetic agents
2015
The nervous system of airways and its remodeling in inflammatory lung diseases
2017
Pyrazole NNRTIs 4: Selection of UK-453,061 (lersivirine) as a Development Candidate
2009
Optimisation of a novel series of selective CNS penetrant CB2 agonists
2011
The use of spirocyclic scaffolds in drug discovery
2014 Standout
PROTAC targeted protein degraders: the past is prologue
2022 Standout
Chemical predictive modelling to improve compound quality
2013
Molecular Recognition in Chemical and Biological Systems
2015
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
2017 Standout
A series of MOF/Ce-based nanozymes with dual enzyme-like activity disrupting biofilms and hindering recolonization of bacteria
2019
The molecular neurobiology of depression
2008 StandoutNature
Trends in the Development of New Antidepressants. Is there a Light at the End of the Tunnel?
2004
Iterative reactions of transient boronic acids enable sequential C–C bond formation
2016
Antimalarial Activity of 4-Metoxychalcones: Docking Studies as Falcipain/Plasmepsin Inhibitors, ADMET and Lipophilic Efficiency Analysis to Identify a Putative Oral Lead Candidate
2013
Rings in Drugs
2014 Standout
Iron Catalysis in Organic Synthesis
2015 Standout
Contribution of Organofluorine Compounds to Pharmaceuticals
2020 Standout
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures
2015 Standout
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Mapping the Efficiency and Physicochemical Trajectories of Successful Optimizations
2018
Cheminformatic Tools for Medicinal Chemists
2010
Update 1 of: Macrolactonizations in the Total Synthesis of Natural Products
2012
Flow chemistry as a discovery tool to access sp2–sp3cross-coupling reactions via diazo compounds
2014
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates
2011 Standout
Precision High-Throughput Proton NMR Spectroscopy of Human Urine, Serum, and Plasma for Large-Scale Metabolic Phenotyping
2014
Nitrile-Containing Pharmaceuticals: Efficacious Roles of the Nitrile Pharmacophore
2010 Standout
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Two-point halogen bonding between 3,6-dihalopyromellitic diimides
2014 StandoutNobel
Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System?
2019 Standout
Catalytic Asymmetric Hydroalkoxylation of C–C Multiple Bonds
2021 StandoutNobel
Trifluoromethyl Oxetanes: Synthesis and Evaluation as a tert‐Butyl Isostere
2017
Lipophilic Efficiency as an Important Metric in Drug Design
2018
Functional Hydrogels as Wound Dressing to Enhance Wound Healing
2021 Standout
Balance of brain oxytocin and vasopressin: implications for anxiety, depression, and social behaviors
2012
Amide bond formation and peptide coupling
2005 Standout
Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone?
2015 Standout
Neurokinin antagonists and their potential role in treating depression and other stress disorders
2004
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
ADMETlab 2.0: an integrated online platform for accurate and comprehensive predictions of ADMET properties
2021 Standout
Host-Gut Microbiota Metabolic Interactions
2012 StandoutScience
An architectonic macrolide library based on a C2-symmetric macrodiolide toward pharmaceutical compositions
2015 StandoutNobel
Quantitative Assessment of the Impact of Fluorine Substitution on P-Glycoprotein (P-gp) Mediated Efflux, Permeability, Lipophilicity, and Metabolic Stability
2016
From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles
2011 Standout
Applications of Fluorine in Medicinal Chemistry
2015 Standout
Improving Drug Design: An Update on Recent Applications of Efficiency Metrics, Strategies for Replacing Problematic Elements, and Compounds in Nontraditional Drug Space
2016
Synthesis and photophysical properties of tetra- and pentaalkynylfluorobenzenes by Sonogashira reactions of novel iodofluorobenzenes
2012
Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry
2020 StandoutNobel
Improving Drug Candidates by Design: A Focus on Physicochemical Properties As a Means of Improving Compound Disposition and Safety
2011
Development of a Scalable Route to a Dual NK-1/Serotonin Receptor Antagonist
2013
Enzyme-Controlled Nitrogen-Atom Transfer Enables Regiodivergent C–H Amination
2014 StandoutNobel
Therapeutic Modulation of Microbiota-Host Metabolic Interactions
2012
Nucleophilic Reactivities of Hydrazines and Amines: The Futile Search for the α-Effect in Hydrazine Reactivities
2012
Works of Thomas Ryckmans being referenced
Design and synthesis of morpholine derivatives. SAR for dual serotonin & noradrenaline reuptake inhibition
2008
Discovery of PF-184563, a potent and selective V1a antagonist for the treatment of dysmenorrhoea. The influence of compound flexibility on microsomal stability
2011
[4-(Phenoxy)pyridin-3-yl]methylamines: A new class of selective noradrenaline reuptake inhibitors
2008
First dual NK1 antagonists–serotonin reuptake inhibitors: synthesis and SAR of a new class of potential antidepressants
2002
Discovery of orally bioavailable NK1 receptor antagonists
2003
Application of Barluenga Boronic Coupling (BBC) to the Parallel Synthesis of Drug‐like and Drug Fragment‐like Molecules
2011
Design and pharmacological evaluation of PF-4840154, a non-electrophilic reference agonist of the TrpA1 channel
2011
Dual NK1 antagonists—serotonin reuptake inhibitors as potential antidepressants. Part 2: SAR and activity of benzyloxyphenethyl piperazine derivatives
2002
Quantitative UPLC-MS/MS analysis of the gut microbial co-metabolites phenylacetylglutamine, 4-cresyl sulphate and hippurate in human urine: INTERMAP Study
2011
Glycomimetic, Orally Bioavailable LecB Inhibitors Block Biofilm Formation of Pseudomonas aeruginosa
2017
Modulation of the vasopressin system for the treatment of CNS diseases.
2010
Dual NK1 Antagonists—Serotonin Reuptake Inhibitors as Potential Antidepressants. Part 2. SAR and Activity of Benzyloxyphenethyl Piperazine Derivatives.
2003
5-Aminopyrazoles from enolisable ketones and 1-cyano-1-alkylhydrazines.
1997
SAR mining and its application to the design of TRPA1 antagonists
2011
Rapid assessment of a novel series of selective CB2 agonists using parallel synthesis protocols: A Lipophilic Efficiency (LipE) analysis
2009
The Discovery of a Potent, Selective, and Peripherally Restricted Pan-Trk Inhibitor (PF-06273340) for the Treatment of Pain
2016
A Concise Total Synthesis of the Lichen Macrolide (+)-Aspicilin
2006