Citation Impact
Citing Papers
Activity-Dependent Internalization of Smoothened Mediated by ß-Arrestin 2 and GRK2
2004 StandoutScienceNobel
Global phosphorylation analysis of β-arrestin–mediated signaling downstream of a seven transmembrane receptor (7TMR)
2010 StandoutNobel
Dishevelled 2 Recruits ß-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4
2003 StandoutScienceNobel
Spinophilin Blocks Arrestin Actions in Vitro and in Vivo at G Protein-Coupled Receptors
2004 StandoutScienceNobel
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
A Modular PIP 2 Binding Site as a Determinant of Capsaicin Receptor Sensitivity
2003 StandoutScienceNobel
Identification of a tight junction–associated guanine nucleotide exchange factor that activates Rho and regulates paracellular permeability
2003
Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors
1996 Nature
Pleiotropic Coupling of G Protein-coupled Receptors to the Mitogen-activated Protein Kinase Cascade
1999 StandoutNobel
cAMP-induced Morphological Changes Are Counteracted by the Activated RhoA Small GTPase and the Rho Kinase ROKα
1998
Phosphatidylinositol 4-Phosphate 5-Kinase Is Essential for ROCK-mediated Neurite Remodeling
2002
Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A
1997 StandoutNatureNobel
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
The Human Cytomegalovirus US11 Gene Product Dislocates MHC Class I Heavy Chains from the Endoplasmic Reticulum to the Cytosol
1996 Standout
Sphingosine 1-Phosphate Rapidly Activates the Mitogen-activated Protein Kinase Pathway by a G Protein-dependent Mechanism
1995
Involvement of a Pertussis Toxin-sensitive G Protein in the Mitogenic Signaling Pathways of Sphingosine 1-Phosphate
1995
Animal models of chronic obstructive pulmonary disease
2008
A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation
1996 Nature
G Protein-coupled Receptors Mediate Two Functionally Distinct Pathways of Tyrosine Phosphorylation in Rat 1a Fibroblasts
1997 StandoutNobel
Dual Effect of β-Adrenergic Receptors on Mitogen-activated Protein Kinase
1995
Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis
1994 StandoutScienceNobel
Rho GTPases in cell biology
2002 StandoutNature
Mutant α subunits of Gi2 inhibit cyclic AMP accumulation
1991 Nature
ErbBs in lung cancer
2008
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
The TRPM7 channel is inactivated by PIP2 hydrolysis
2002
Differential Coupling of α1-, α2-, and β-Adrenergic Receptors to Mitogen-activated Protein Kinase Pathways and Differentiation in Transfected PC12 Cells
1998
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
1992 Standout
An Integrated Phosphoproteomics Work Flow Reveals Extensive Network Regulation in Early Lysophosphatidic Acid Signaling
2010
β Phorbol Ester- and Diacylglycerol-Induced Augmentation of Transmitter Release Is Mediated by Munc13s and Not by PKCs
2002 StandoutNobel
The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
1992 Standout
Mitogenic Signaling via G Protein-Coupled Receptors
1996 StandoutNobel
Ras-dependent Mitogen-activated Protein Kinase Activation by G Protein-coupled Receptors
1997 StandoutNobel
Requirement for Rho-mediated Myosin Light Chain Phosphorylation in Thrombin-stimulated Cell Rounding and Its Dissociation from Mitogenesis
1998
Rho signaling and mechanical control of vascular development
2008
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
Characterization of the expression of PDZ‐RhoGEF, LARG and Gα12/Gα13 proteins in the murine nervous system
2002
Lysophosphatidic Acid, a Multifunctional Phospholipid Messenger
1995
Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx
1993 StandoutNatureNobel
Sphingosylphosphorylcholine Activation of Mitogen-activated Protein Kinase in Swiss 3T3 Cells Requires Protein Kinase C and a Pertussis Toxin-sensitive G Protein
1995
The Role of Oxidative Stress in Chronic Obstructive Pulmonary Disease
2004
Role of c-Src Tyrosine Kinase in G Protein-coupled Receptorand Gβγ Subunit-mediated Activation of Mitogen-activated Protein Kinases
1996 StandoutNobel
Insulin disrupts β-adrenergic signalling to protein kinase A in adipocytes
2005 StandoutNatureNobel
Structure–activity relationships of lysophosphatidic acid analogs
2002
Chronic obstructive pulmonary disease: molecular and cellularmechanisms
2003
Use of Synthetic Peptides in the Dissection of Protein-Targeting Interactions
2003
Dual modulation of cell survival and cell death by β 2 -adrenergic signaling in adult mouse cardiac myocytes
2001 StandoutNobel
Enhanced Morphine Analgesia in Mice Lacking β-Arrestin 2
1999 StandoutScienceNobel
Identification of a putative membrane receptor for the bioactive phospholipid, lysophosphatidic acid.
1992
Signal transduction pathways regulating Rho-mediated stress fibre formation: requirement for a tyrosine kinase.
1994
Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering
2001 StandoutNobel
β 2 -Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein
1998 StandoutNobel
Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway
1995 StandoutNatureNobel
Pertussis toxin-sensitive activation of p21ras by G protein-coupled receptor agonists in fibroblasts.
1993
β-Arrestin-Dependent Formation of β 2 Adrenergic Receptor-Src Protein Kinase Complexes
1999 StandoutScienceNobel
Alpha 2-adrenergic agonists stimulate DNA synthesis in Chinese hamster lung fibroblasts transfected with a human alpha 2-adrenergic receptor gene.
1990 StandoutNobel
Lysophosphatidic acid possesses dual action in cellproliferation.
1994
RapV12 antagonizes Ras-dependent activation of ERK1 and ERK2 by LPA and EGF in Rat-1 fibroblasts.
1993
Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21ras.
1994 StandoutNobel
μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence
2000 StandoutNatureNobel
Activation of the small GTP-binding proteins rho and rac by growth factor receptors
1995
β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3
2000 StandoutScienceNobel
Analysis of the fibroblast transformation potential of GTPase-deficient gip2 oncogenes.
1992
Angiotensin II Activates pp60c-srcin Vascular Smooth Muscle Cells
1995
Distinct signals via Rho GTPases and Src drive shape changes by thrombin and sphingosine-1-phosphate in endothelial cells
2002
Muscarinic acetylcholine receptor subtypes as agonist-dependent oncogenes.
1991
A mutant alpha subunit of Gi2 induces neoplastic transformation of Rat-1 cells.
1991
Ligand-independent activation of platelet-derived growth factor receptor is a necessary intermediate in lysophosphatidic, acid-stimulated mitogenic activity in L cells
1998
Calcium mobilization and Rac1 activation are required for VCAM-1 (vascular cell adhesion molecule-1) stimulation of NADPH oxidase activity
2004
Role of RhoA and Rho Kinase in Lysophosphatidic Acid–Induced Endothelial Barrier Dysfunction
2000
Different G protein-coupled receptor kinases govern G protein and β-arrestin-mediated signaling of V2 vasopressin receptor
2005 StandoutNobel
Involvement of Ras and Raf in the Gi-coupled acetylcholine muscarinic m2 receptor activation of mitogen-activated protein (MAP) kinase kinase and MAP kinase.
1993
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
Export of protein from the endoplasmic reticulum is regulated by a diacylglycerol/phorbol ester binding protein.
1994
Activation of Src family kinase activity by the G protein-coupled thrombin receptor in growth-responsive fibroblasts.
1994
Lysophosphatidic acid, but not phosphatidic acid, is a potent Ca2(+)-mobilizing stimulus for fibroblasts. Evidence for an extracellular site of action.
1990
Gi-mediated activation of the p21ras-mitogen-activated protein kinase pathway by alpha 2-adrenergic receptors expressed in fibroblasts.
1993
cAMP abrogates the p21ras-mitogen-activated protein kinase pathway in fibroblasts.
1994
The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors.
1994
The Cdc42 and Rac1 GTPases are required for capillary lumen formation in three-dimensional extracellular matrices
2002
Functional antagonism of different G protein-coupled receptor kinases for β-arrestin-mediated angiotensin II receptor signaling
2005 StandoutNobel
G PROTEIN–COUPLED RECEPTOR KINASES
1998 StandoutNobel
Ca2+Sensitivity of Smooth Muscle and Nonmuscle Myosin II: Modulated by G Proteins, Kinases, and Myosin Phosphatase
2003 Standout
Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds
2001 StandoutNobel
Two G Protein Oncogenes in Human Endocrine Tumors
1990 Science
Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells
2001 StandoutNobel
Lysophosphatidic acid stimulates mitogen-activated protein kinase activation via a G-protein-coupled pathway requiring p21ras and p74raf-1.
1993
Protein tyrosine phosphorylation induced by lysophosphatidic acid in Rat-1 fibroblasts. Evidence that phosphorylation of map kinase is mediated by the Gi-p21ras pathway.
1994
Sphingosine 1-phosphate stimulates Rho-mediated tyrosine phosphorylation of focal adhesion kinase and paxillin in Swiss 3T3 fibroblasts
1997
Inhibition of Adenylyl Cyclase by G iα
1993 StandoutScienceNobel
Suppression of Ras-Induced Transformation of NIH 3T3 Cells by Activated Gα S
1994 Science
Signal transduction through the GTP-binding proteins Rac and Rho
1994
THE UBIQUITIN SYSTEM
1998 StandoutNobel
A Region of Adenylyl Cyclase 2 Critical for Regulation by G Protein βγ Subunits
1995 StandoutScienceNobel
The Role of Rho in G Protein-Coupled Receptor Signal Transduction
2000
Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors
2000 StandoutNobel
ß-Arrestin 2 Mediates Endocytosis of Type III TGF-ß Receptor and Down-Regulation of Its Signaling
2003 StandoutScienceNobel
Transduction of Receptor Signals by ß-Arrestins
2005 StandoutScienceNobel
Desensitization, internalization, and signaling functions of β-arrestins demonstrated by RNA interference
2003 StandoutNobel
Works of Thomas Eichholtz being referenced
New model of ErbB-2 over-expression in human mammary luminal epithelial cells
1999
A pseudosubstrate peptide inhibits protein kinase C‐mediated phosphorylation in permeabilized Rat‐1 cells
1990
Lysophosphatidate-induced cell proliferation: Identification and dissection of signaling pathways mediated by G proteins
1989
Latent adenoviral infection induces production of growth factors relevant to airway remodeling in COPD
2004
Involvement of MMP-12 and phosphodiesterase type 4 in cigarette smoke-induced inflammation in mice
2006
Lysophosphatidic acid induces neuronal shape changes via a novel, receptor-mediated signaling pathway: similarity to thrombin action.
1993
Rho and Rac but not Cdc42 regulate endothelial cell permeability
2001
GM-CSF increases airway smooth muscle cell connective tissue expression by inducing TGF-β receptors
2003
Activation of protein kinase C accelerates internalization of transferrin receptor but not of major histocompatibility complex class I, independent of their phosphorylation status.
1992
A myristoylated pseudosubstrate peptide, a novel protein kinase C inhibitor.
1993
The bioactive phospholipid lysophosphatidic acid is released from activated platelets
1993