Standout Papers
- Improving NMR protein structure quality by Rosetta refinement: A molecular replacement study (2008)
- A hybrid NMR/SAXS‐based approach for discriminating oligomeric protein interfaces using
R osetta (2014) - Principles for designing ideal protein structures (2012)
- Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples (2012)
Citation Impact
Citing Papers
An enumerative algorithm for de novo design of proteins with diverse pocket structures
2020 StandoutNobel
NMR data collection and analysis protocol for high-throughput protein structure determination
2005
Principles for designing proteins with cavities formed by curved β sheets
2017 StandoutScienceNobel
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Design of structurally distinct proteins using strategies inspired by evolution
2016 Science
Improved protein structure prediction using predicted interresidue orientations
2020 StandoutNobel
De novo design of transmembrane β barrels
2021 StandoutScienceNobel
Protein structure determination using metagenome sequence data
2017 StandoutScienceNobel
De novo design of a transmembrane Zn 2+ -transporting four-helix bundle
2014 Science
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
2020 StandoutScienceNobel
Expanding the space of protein geometries by computational design of de novo fold families
2020 Science
Sculpting conducting nanopore size and shape through de novo protein design
2024 StandoutScienceNobel
Computation and Functional Studies Provide a Model for the Structure of the Zinc Transporter hZIP4
2015 StandoutNobel
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
Design of symmetric TIM barrel proteins from first principles
2015
De novo design of immunoglobulin-like domains
2022 StandoutNobel
Sampling of structure and sequence space of small protein folds
2022 StandoutNobel
CpSufE Activates the Cysteine Desulfurase CpNifS for Chloroplastic Fe-S Cluster Formation
2006
Improvements to Robotics-Inspired Conformational Sampling in Rosetta
2013
SEC14L2 enables pan-genotype HCV replication in cell culture
2015 StandoutNatureNobel
phenix.mr_rosetta: molecular replacement and model rebuilding with Phenix and Rosetta
2012 StandoutNobel
Protein design with fragment databases
2011
Modular and tunable biological feedback control using a de novo protein switch
2019 StandoutNatureNobel
How Escherichia coli and Saccharomyces cerevisiae Build Fe/S Proteins
2005
Rational design of proteins that exchange on functional timescales
2017
Evolution, folding, and design of TIM barrels and related proteins
2021
Improved chemical shift based fragment selection for CS-Rosetta using Rosetta3 fragment picker
2013 StandoutNobel
Protein structure prediction from sequence variation
2012
Bottom-up de novo design of functional proteins with complex structural features
2021
Design of proteins from smaller fragments—learning from evolution
2014
A novel strategy for NMR resonance assignment and protein structure determination
2010
Iron–sulfur-protein biogenesis in eukaryotes
2005
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Engineering the entropy-driven free-energy landscape of a dynamic nanoporous protein assembly
2018
PDBStat: a universal restraint converter and restraint analysis software package for protein NMR
2013
Artificial Diiron Enzymes with a De Novo Designed Four‐Helix Bundle Structure
2015
An Integrated Platform for Automated Analysis of Protein NMR Structures
2005
A walk-through of the yeast mating pheromone response pathway
2004
Opportunities and challenges in design and optimization of protein function
2024
De novo design of luciferases using deep learning
2023 StandoutNatureNobel
Crystal structure of nanoKAZ: The mutated 19 kDa component of Oplophorus luciferase catalyzing the bioluminescent reaction with coelenterazine
2015
Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3
2017 StandoutNatureNobel
SufE Transfers Sulfur from SufS to SufB for Iron-Sulfur Cluster Assembly
2007
Protein stability: computation, sequence statistics, and new experimental methods
2015
A Brief History of De Novo Protein Design: Minimal, Rational, and Computational
2021
Improved Technologies Now Routinely Provide Protein NMR Structures Useful for Molecular Replacement
2011
Rational design of α-helical tandem repeat proteins with closed architectures
2015 StandoutNatureNobel
Enzymatic assembly of carbon–carbon bonds via iron-catalysed sp3 C–H functionalization
2018 StandoutNatureNobel
Recommendations of the wwPDB NMR Validation Task Force
2013
A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells
2014 StandoutNobel
Thioredoxin Reductase System Mediates Iron Binding in IscA and Iron Delivery for the Iron-Sulfur Cluster Assembly in IscU*
2005
An Ancient Fingerprint Indicates the Common Ancestry of Rossmann-Fold Enzymes Utilizing Different Ribose-Based Cofactors
2016
Role of backbone strain in de novo design of complex α/β protein structures
2021 StandoutNobel
Computational design of self-assembling cyclic protein homo-oligomers
2016 StandoutNobel
The coming of age of de novo protein design
2016 StandoutNatureNobel
Conformational changes in the G protein Gs induced by the β2 adrenergic receptor
2011 StandoutNatureNobel
Design of biologically active binary protein 2D materials
2021 StandoutNatureNobel
A backbone-centred energy function of neural networks for protein design
2022 Nature
Improving 3D structure prediction from chemical shift data
2013 StandoutNobel
De Novo Proteins with Life-Sustaining Functions Are Structurally Dynamic
2015
Design of functionalised circular tandem repeat proteins with longer repeat topologies and enhanced subunit contact surfaces
2021
A Pareto-Optimal Refinement Method for Protein Design Scaffolds
2013 StandoutNobel
Interplay of IscA and IscU in Biogenesis of Iron-Sulfur Clusters
2006
Improved protein structure prediction using potentials from deep learning
2020 StandoutNatureNobel
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
De novo design of bioactive protein switches
2019 StandoutNatureNobel
Alternate States of Proteins Revealed by Detailed Energy Landscape Mapping
2010 StandoutNobel
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
The Protein Structure Initiative: achievements and visions for the future
2012
De novo design of a non-local β-sheet protein with high stability and accuracy
2018 StandoutNobel
Quantitative reactivity profiling predicts functional cysteines in proteomes
2010 StandoutNatureNobel
The HCV Life Cycle: In vitro Tissue Culture Systems and Therapeutic Targets
2014 Standout
Tertiary Structural Propensities Reveal Fundamental Sequence/Structure Relationships
2015
De novo design of a four-fold symmetric TIM-barrel protein with atomic-level accuracy
2015 StandoutNobel
Forced protein unfolding leads to highly elastic and tough protein hydrogels
2013 StandoutNobel
Exploring the repeat protein universe through computational protein design
2015 StandoutNatureNobel
Programmable design of orthogonal protein heterodimers
2018 StandoutNatureNobel
Controlling protein assembly on inorganic crystals through designed protein interfaces
2019 StandoutNatureNobel
Protein 3D Structure Computed from Evolutionary Sequence Variation
2011
A topology‐constrained distance network algorithm for protein structure determination from NOESY data
2005
Cryo-EM structure of a type IV secretion system
2022 StandoutNatureNobel
A General Computational Approach for Repeat Protein Design
2014 StandoutNobel
Deep mutational scanning: a new style of protein science
2014
An accurate binding interaction model in de novo computational protein design of interactions: If you build it, they will bind
2013
De novo protein design by deep network hallucination
2021 StandoutNatureNobel
A walk-through of the yeast mating pheromone response pathway
2004
Function and biogenesis of iron–sulphur proteins
2009 Nature
De novo protein design by inversion of the AlphaFold structure prediction network
2023
Simple yet functional phosphate-loop proteins
2018 StandoutNobel
Accurate design of megadalton-scale two-component icosahedral protein complexes
2016 StandoutScienceNobel
Precise assembly of complex beta sheet topologies from de novo designed building blocks
2015 StandoutNobel
Iron-Sulfur Protein Biogenesis in Eukaryotes: Components and Mechanisms
2006
Critical assessment of methods of protein structure prediction (CASP) — round x
2013
Computational design of water-soluble α-helical barrels
2014 Science
Occurrence, Classification, and Biological Function of Hydrogenases: An Overview
2007 Standout
Protein NMR Structures Refined with Rosetta Have Higher Accuracy Relative to Corresponding X-ray Crystal Structures
2014 StandoutNobel
De novo design of protein homo-oligomers with modular hydrogen-bond network–mediated specificity
2016 StandoutScienceNobel
Robust and accurate prediction of residue–residue interactions across protein interfaces using evolutionary information
2014 StandoutNobel
Heme Enzyme Structure and Function
2014
Analysis of the Heteromeric CsdA-CsdE Cysteine Desulfurase, Assisting Fe-S Cluster Biogenesis in Escherichia coli
2005
Computational redesign of the lipid-facing surface of the outer membrane protein OmpA
2015
Accurate Automated Protein NMR Structure Determination Using Unassigned NOESY Data
2009 StandoutNobel
De novo protein fold design through sequence-independent fragment assembly simulations
2023
De novo design of small beta barrel proteins
2023 StandoutNobel
CCBuilder: an interactive web-based tool for building, designing and assessing coiled-coil protein assemblies
2014
Networks of electrostatic and hydrophobic interactions modulate the complex folding free energy surface of a designed βα protein
2019 StandoutNobel
Control over overall shape and size in de novo designed proteins
2015 StandoutNobel
Allosteric cooperation in a de novo-designed two-domain protein
2020
Analysis of Protein Conformation and Dynamics by Hydrogen/Deuterium Exchange MS
2009
Essentials of de novo protein design: Methods and applications
2018
Large-scale determination of previously unsolved protein structures using evolutionary information
2015 StandoutNobel
Consistency principle for protein design
2019
C–C bond forming radical SAM enzymes involved in the construction of carbon skeletons of cofactors and natural products
2018
Analysis of iron–sulfur protein maturation in eukaryotes
2009
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
Combined Covalent-Electrostatic Model of Hydrogen Bonding Improves Structure Prediction with Rosetta
2015 StandoutNobel
Protein Assembly by Design
2021
What has de novo protein design taught us about protein folding and biophysics?
2019 StandoutNobel
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Works of Thomas Acton being referenced
Structural and biochemical studies identify tobacco SABP2 as a methyl salicylate esterase and implicate it in plant innate immunity
2005
A microscale protein NMR sample screening pipeline
2009
Structural genomics is the largest contributor of novel structural leverage
2009
Functional insights from structural genomics
2007
Solution NMR Structure of the Iron–Sulfur Cluster Assembly Protein U (IscU) with Zinc Bound at the Active Site
2004
Cold-shock induced high-yield protein production in Escherichia coli
2004
Solution NMR structure of Alr2454 from Nostoc sp. PCC 7120, the first structural representative of Pfam domain family PF11267
2012
Construct optimization for protein NMR structure analysis using amide hydrogen/deuterium exchange mass spectrometry
2009
The SufE Sulfur-acceptor Protein Contains a Conserved Core Structure that Mediates Interdomain Interactions in a Variety of Redox Protein Complexes
2004
Principles for designing ideal protein structures
2012 StandoutNatureNobel
Improving NMR protein structure quality by Rosetta refinement: A molecular replacement study
2008 StandoutNobel
Automatic target selection for structural genomics on eukaryotes
2004
Two Fe-S clusters catalyze sulfur insertion by radical-SAM methylthiotransferases
2013
High‐quality homology models derived from NMR and X‐ray structures of E. coli proteins YgdK and Suf E suggest that all members of the YgdK/Suf E protein family are enhancers of cysteine desulfurases
2005
Comparisons of NMR Spectral Quality and Success in Crystallization Demonstrate that NMR and X-ray Crystallography Are Complementary Methods for Small Protein Structure Determination
2005
Interactions of the Mcm1 MADS Box Protein with Cofactors That Regulate Mating in Yeast
2002
Solution NMR structure of the 30S ribosomal protein S28E from Pyrococcus horikoshii
2003
Molecular insights into substrate recognition and catalysis by tryptophan 2,3-dioxygenase
2006
Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples
2012 StandoutNobel