Standout Papers

Hematopoiesis: An Evolving Paradigm for Stem C... 1990 2026 2002 2014 1.7k
  1. Hematopoiesis: An Evolving Paradigm for Stem Cell Biology (2008)
    Stuart H. Orkin, Leonard I. Zon Cell
  2. An early haematopoietic defect in mice lacking the transcription factor GATA-2 (1994)
    Fong‐Ying Tsai, Gordon Keller et al. Nature
  3. Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1 (1991)
    Larysa Pevny, Elizabeth Robertson et al. Nature
  4. Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping (1990)
    Manfred Gessler, Annemarie Poustka et al. Nature
  5. An Extended Transcriptional Network for Pluripotency of Embryonic Stem Cells (2008)
    Jonghwan Kim, Jianlin Chu et al. Cell
  6. A protein interaction network for pluripotency of embryonic stem cells (2006)
    Jianlong Wang, Sridhar Rao et al. Nature
  7. Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells (1989)
    Shih‐Feng Tsai, David I. K. Martin et al. Nature
  8. Linkage of β-thalassaemia mutations and β-globin gene polymorphisms with DNA polymorphisms in human β-globin gene cluster (1982)
    Stuart H. Orkin, Haig H. Kazazian et al. Nature
  9. EZH1 Mediates Methylation on Histone H3 Lysine 27 and Complements EZH2 in Maintaining Stem Cell Identity and Executing Pluripotency (2008)
    Xiaohua Shen, Yingchun Liu et al. Molecular Cell
  10. Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL (1995)
    Ramesh A. Shivdasani, Erica L. Mayer et al. Nature
  11. Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based RNAi Library (2004)
    Jean‐François Rual, Julián Cerón et al. Genome Research
  12. A Critical Role for Eosinophils in Allergic Airways Remodeling (2004)
    Alison A. Humbles, Clare M. Lloyd et al. Science
  13. Cloning the gene for an inherited human disorder—chronic granulomatous disease—on the basis of its chromosomal location (1986)
    Brigitte Royer‐Pokora, Louis M. Kunkel et al. Nature
  14. E2F-1 Functions in Mice to Promote Apoptosis and Suppress Proliferation (1996)
    Seth J. Field, Fong‐Ying Tsai et al. Cell
  15. Human Fetal Hemoglobin Expression Is Regulated by the Developmental Stage-Specific Repressor BCL11A (2008)
    Vijay G. Sankaran, Tobias Menne et al. Science
  16. Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression (2003)
    Carola A. Neumann, Daniela S. Krause et al. Nature
  17. Endogenous oncogenic K-rasG12D stimulates proliferation and widespread neoplastic and developmental defects (2004)
    David A. Tuveson, Alice T. Shaw et al. Cancer Cell
  18. Mouse GATA-4: a retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heart. (1993)
    R.J. Arceci, Stuart H. Orkin et al. Molecular and Cellular Biology
  19. Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1. (1996)
    Yuko Fujiwara, Sabra C. Goff et al. Proceedings of the National Academy of Sciences
  20. Tet1 and Tet2 Regulate 5-Hydroxymethylcytosine Production and Cell Lineage Specification in Mouse Embryonic Stem Cells (2011)
    Kian Peng Koh, Akiko Yabuuchi et al. Cell stem cell
  21. BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis (2015)
    Matthew C. Canver, Elenoe C. Smith et al. Nature
  22. FOG, a Multitype Zinc Finger Protein, Acts as a Cofactor for Transcription Factor GATA-1 in Erythroid and Megakaryocytic Differentiation (1997)
    Jane E. Visvader, Yuko Fujiwara et al. Cell
  23. The T Cell Leukemia Oncoprotein SCL/tal-1 Is Essential for Development of All Hematopoietic Lineages (1996)
    Catherine Porcher, Wojciech Swat et al. Cell
  24. Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoeitin/MGDF in megakaryocyte development (1995)
    Ramesh A. Shivdasani, Margery Rosenblatt et al. Cell
  25. Erythroid transcription factor NF-E2 is a haematopoietic-specific basic–leucine zipper protein (1993)
    Nancy C. Andrews, Hediye Erdjument‐Bromage et al. Nature
  26. DNA-Binding Specificity of GATA Family Transcription Factors (1993)
    Menie Merika, Stuart H. Orkin Molecular and Cellular Biology
  27. Specific transcription and RNA splicing defects in five cloned β-thalassaemia genes (1983)
    Richard Treisman, Stuart H. Orkin et al. Nature
  28. A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development (1997)
    Ramesh A. Shivdasani, Yuko Fujiwara et al. The EMBO Journal
  29. Lethal β-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF (1995)
    Arlene H. Sharpe, Stuart H. Orkin et al. Nature
  30. A Myc Network Accounts for Similarities between Embryonic Stem and Cancer Cell Transcription Programs (2010)
    Jonghwan Kim, Andrew J. Woo et al. Cell
  31. An Erythroid Enhancer of BCL11A Subject to Genetic Variation Determines Fetal Hemoglobin Level (2013)
    Daniel E. Bauer, Sophia C. Kamran et al. Science
  32. Hydroxyurea enhances fetal hemoglobin production in sickle cell anemia. (1984)
    O Platt, Stuart H. Orkin et al. Journal of Clinical Investigation
  33. Differentiation in erythroleukemic cells and their somatic hybrids. (1975)
    Stuart H. Orkin, Ferenc I. Hárosi et al. Proceedings of the National Academy of Sciences
  34. Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch (2018)
    Nan Liu, Victoria V. Hargreaves et al. Cell

Immediate Impact

18 by Nobel laureates 80 from Science/Nature 131 standout
Sub-graph 1 of 18

Citing Papers

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26 intermediate papers

Works of Stuart H. Orkin being referenced

ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling
2008
Dysregulation of protein modification by ISG15 results in brain cell injury
2002
and 34 more

Author Peers

Author Last Decade Papers Cites
Stuart H. Orkin 50761 14145 16448 537 75.5k
Harvey F. Lodish 46181 5245 6583 572 76.6k
Irving L. Weissman 58306 16614 24314 826 129.3k
Benjamin L. Ebert 45494 8722 13755 287 71.1k
Toshio Suda 31977 5091 10128 723 57.6k
George Q. Daley 36199 6156 7301 386 49.3k
Neal G. Copeland 42413 3941 2988 622 72.4k
Philip Leder 40876 4182 3697 351 63.1k
Sean J. Morrison 31942 9185 12602 181 61.2k
Pier Paolo Pandolfi 61139 3518 7973 449 79.2k
Leonard I. Zon 29107 4010 7206 483 48.0k

All Works

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