Standout Papers

Microfluidics: Fluid physics at the nanoliter scale 2000 2026 2008 2017 3.2k
  1. Microfluidics: Fluid physics at the nanoliter scale (2005)
    Todd M. Squires, Stephen R. Quake Reviews of Modern Physics
  2. Monolithic Microfabricated Valves and Pumps by Multilayer Soft Lithography (2000)
    Marc Unger, Hou-Pu Chou et al. Science
  3. Microfluidic Large-Scale Integration (2002)
    Todd Thorsen, Sebastian J. Maerkl et al. Science
  4. Dynamic Pattern Formation in a Vesicle-Generating Microfluidic Device (2001)
    Todd Thorsen, Richard W. Roberts et al. Physical Review Letters
  5. Developing optofluidic technology through the fusion of microfluidics and optics (2006)
    Demetri Psaltis, Stephen R. Quake et al. Nature
  6. Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq (2014)
    Barbara Treutlein, Douglas Brownfield et al. Nature
  7. Single-cell genome sequencing: current state of the science (2016)
    Charles Gawad, Winston Koh et al. Nature Reviews Genetics
  8. From Micro- to Nanofabrication with Soft Materials (2000)
    Stephen R. Quake, Axel Scherer Science
  9. A survey of human brain transcriptome diversity at the single cell level (2015)
    Spyros Darmanis, Steven A. Sloan et al. Proceedings of the National Academy of Sciences
  10. A molecular cell atlas of the human lung from single-cell RNA sequencing (2020)
    Kyle J. Travaglini, Ahmad N. Nabhan et al. Nature
  11. Noninvasive diagnosis of fetal aneuploidy by shotgun sequencing DNA from maternal blood (2008)
    H. Christina Fan, Yair J. Blumenfeld et al. Proceedings of the National Academy of Sciences
  12. Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing (2018)
    Qingyun Li, Zuolin Cheng et al. Neuron
  13. Single-cell NF-κB dynamics reveal digital activation and analogue information processing (2010)
    Savaş Tay, Jacob Hughey et al. Nature
  14. A microfabricated fluorescence-activated cell sorter (1999)
    Charles Spence, Axel Scherer et al. Nature Biotechnology
  15. Single-Cell RNA-Seq Analysis of Infiltrating Neoplastic Cells at the Migrating Front of Human Glioblastoma (2017)
    Spyros Darmanis, Steven A. Sloan et al. Cell Reports
  16. Microfluidic Digital PCR Enables Multigene Analysis of Individual Environmental Bacteria (2006)
    Elizabeth A. Ottesen, Jong Wook Hong et al. Science
  17. Quantitative assessment of single-cell RNA-sequencing methods (2013)
    Angela Ruohao Wu, Norma Neff et al. Nature Methods
  18. Clonal Evolution of Preleukemic Hematopoietic Stem Cells Precedes Human Acute Myeloid Leukemia (2012)
    Max Jan, Thomas M. Snyder et al. Science Translational Medicine
  19. Microfluidic Large-Scale Integration: The Evolution of Design Rules for Biological Automation (2007)
    Jessica Melin, Stephen R. Quake Annual Review of Biophysics and Biomolecular Structure
  20. c-Jun overexpression in CAR T cells induces exhaustion resistance (2019)
    Rachel C. Lynn, Evan W. Weber et al. Nature
  21. The promise and challenge of high-throughput sequencing of the antibody repertoire (2014)
    George Georgiou, Gregory C. Ippolito et al. Nature Biotechnology
  22. Long-Term Monitoring of Bacteria Undergoing Programmed Population Control in a Microchemostat (2005)
    Frederick Balagadde, Lingchong You et al. Science
  23. Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells (2017)
    Steven A. Sloan, Spyros Darmanis et al. Neuron
  24. An Integrated Microfabricated Cell Sorter (2002)
    Hou-Pu Chou, Charles Spence et al. Analytical Chemistry
  25. Circulating Cell-Free DNA Enables Noninvasive Diagnosis of Heart Transplant Rejection (2014)
    Iwijn De Vlaminck, Hannah A. Valantine et al. Science Translational Medicine
  26. Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns (2017)
    Martin Enge, H. Efsun Arda et al. Cell
  27. Single-cell transcriptomic atlas of the human endometrium during the menstrual cycle (2020)
    Wanxin Wang, Felipe Vilella et al. Nature Medicine
  28. Early prediction of preeclampsia in pregnancy with cell-free RNA (2022)
    Mira N. Moufarrej, Sevahn K. Vorperian et al. Nature
  29. Spatial transcriptomics reveal neuron–astrocyte synergy in long-term memory (2024)
    Wenfei Sun, Zhihui Liu et al. Nature

Immediate Impact

13 by Nobel laureates 61 from Science/Nature 139 standout
Sub-graph 1 of 17

Citing Papers

Genetic manipulation of Patescibacteria provides mechanistic insights into microbial dark matter and the epibiotic lifestyle
2023 StandoutNobel
Sulfur [ 18 F]Fluoride Exchange Click Chemistry Enabled Ultrafast Late-Stage Radiosynthesis
2021 StandoutNobel
16 intermediate papers

Works of Stephen R. Quake being referenced

Dissecting biological “dark matter” with single-cell genetic analysis of rare and uncultivated TM7 microbes from the human mouth
2007
Multistep Synthesis of a Radiolabeled Imaging Probe Using Integrated Microfluidics
2005 Science
and 3 more

Author Peers

Author Last Decade Papers Cites
Stephen R. Quake 18282 20034 4514 7368 348 48.5k
Sanjiv S. Gambhir 23802 24209 3200 2798 689 64.0k
David A. Weitz 18229 43930 1768 17150 809 96.7k
Ronald W. Davis 55358 10075 3344 3324 539 82.7k
Jeremy C. Smith 31235 5338 1942 2041 818 56.8k
Mehmet Toner 9869 20705 1358 3521 434 39.7k
Donald E. Ingber 28515 39217 2537 2630 435 86.3k
Kevin W. Eliceiri 40926 15452 6359 3432 299 116.5k
Peter G. Schultz 50248 4356 3210 2734 690 72.2k
Sangeeta N. Bhatia 11478 18700 1165 2215 263 34.8k
Ralph Weissleder 45101 35180 16041 2714 1.1k 115.4k

All Works

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2026