Citation Impact
Citing Papers
Generation of knock-in primary human T cells using Cas9 ribonucleoproteins
2015 StandoutNobel
Limits of long-term selection against Neandertal introgression
2019 StandoutNobel
fastp: an ultra-fast all-in-one FASTQ preprocessor
2018 Standout
VIRTUS: a pipeline for comprehensive virus analysis from conventional RNA-seq data
2020 StandoutNobel
Infrared molecular fingerprinting of blood-based liquid biopsies for the detection of cancer
2021 StandoutNobel
Fast and sensitive mapping of nanopore sequencing reads with GraphMap
2016
The Ensembl Variant Effect Predictor
2016 Standout
CRISPR/Cas9-mediated targeted chromosome elimination
2017
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Complex rearrangements and oncogene amplifications revealed by long-read DNA and RNA sequencing of a breast cancer cell line
2018
clusterProfiler 4.0: A universal enrichment tool for interpreting omics data
2021 Standout
Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice
2020
DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants
2016 Standout
Mechanisms, regulation and functions of the unfolded protein response
2020 Standout
A view on drug resistance in cancer
2019 StandoutNature
Simultaneous targeting of linked loci in mouse embryos using base editing
2019
Single-cell-resolution transcriptome map of human, chimpanzee, bonobo, and macaque brains
2020 StandoutNobel
Expanding the Biologist’s Toolkit with CRISPR-Cas9
2015 StandoutNobel
Accurate detection of complex structural variations using single-molecule sequencing
2018
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future
2017 Standout
Efficient Coalescent Simulation and Genealogical Analysis for Large Sample Sizes
2016
A Neanderthal Sodium Channel Increases Pain Sensitivity in Present-Day Humans
2020 StandoutNobel
From human genome to cancer genome: The first decade
2013
CRISPR–Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV–host factor interactions
2018 StandoutNobel
The Cancer Genome Atlas Pan-Cancer analysis project
2013 Standout
Cancer stem cells revisited
2017 Standout
Expanding the computational toolbox for mining cancer genomes
2014
A Cas9 Ribonucleoprotein Platform for Functional Genetic Studies of HIV-Host Interactions in Primary Human T Cells
2016 StandoutNobel
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
2016 Standout
Metazoan MicroRNAs
2018 Standout
Long non-coding RNAs: new players in cell differentiation and development
2013 Standout
The Unfolded Protein Response: Detecting and Responding to Fluctuations in the Protein-Folding Capacity of the Endoplasmic Reticulum
2019
Nanopore sequencing detects structural variants in cancer
2016
Liquid biopsies come of age: towards implementation of circulating tumour DNA
2017 Standout
Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
2020 Standout
Functional mapping and annotation of genetic associations with FUMA
2017 Standout
Oxidative Stress in Cancer
2020 Standout
Fast and accurate de novo genome assembly from long uncorrected reads
2017 Standout
An integrative variant analysis pipeline for accurate genotype/haplotype inference in population NGS data
2013
Coming of age: ten years of next-generation sequencing technologies
2016 Standout
SVScore: an impact prediction tool for structural variation
2016
GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
2014 Standout
Assembly of long, error-prone reads using repeat graphs
2019 Standout
Efficient Ablation of Genes in Human Hematopoietic Stem and Effector Cells using CRISPR/Cas9
2014
ANGSD: Analysis of Next Generation Sequencing Data
2014 Standout
Efficient generation of mouse models of human diseases via ABE- and BE-mediated base editing
2018 Standout
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
The PI3K Pathway in Human Disease
2017 Standout
Cornerstones of CRISPR–Cas in drug discovery and therapy
2016 StandoutNobel
metaSPAdes: a new versatile metagenomic assembler
2017 Standout
TIGRA: A targeted iterative graph routing assembler for breakpoint assembly
2013
Importance of Long Non-coding RNAs in the Development and Disease of Skeletal Muscle and Cardiovascular Lineages
2019
Maftools: efficient and comprehensive analysis of somatic variants in cancer
2018 Standout
VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research
2016
Low Incidence of Off-Target Mutations in Individual CRISPR-Cas9 and TALEN Targeted Human Stem Cell Clones Detected by Whole-Genome Sequencing
2014
Gene regulation by long non-coding RNAs and its biological functions
2020 Standout
Organoid single-cell genomic atlas uncovers human-specific features of brain development
2019 StandoutNatureNobel
Identification of copy number variants in whole-genome data using Reference Coverage Profiles
2015 StandoutNobel
Minimap2: pairwise alignment for nucleotide sequences
2018 Standout
CADD: predicting the deleteriousness of variants throughout the human genome
2018 Standout
TIMER2.0 for analysis of tumor-infiltrating immune cells
2020 Standout
MetaQUAST: evaluation of metagenome assemblies
2015
Versatile genome assembly evaluation with QUAST-LG
2018
Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3
2017
Spatiotemporal transcriptomic divergence across human and macaque brain development
2018 Science
Wound Healing: A Cellular Perspective
2018 Standout
Control of mitochondrial metabolism and systemic energy homeostasis by microRNAs 378 and 378*
2012
Epigenomic annotation-based interpretation of genomic data: from enrichment analysis to machine learning
2017
A general strategy to construct small molecule biosensors in eukaryotes
2015 StandoutNobel
The DisGeNET knowledge platform for disease genomics: 2019 update
2019 Standout
Biogenesis and function of non-coding RNAs in muscle differentiation and in Duchenne muscular dystrophy
2013
Twelve years of SAMtools and BCFtools
2021 Standout
Characterization of structural variants with single molecule and hybrid sequencing approaches
2014
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Works of Ryan M. Layer being referenced
Notch3 and Mef2c Proteins Are Mutually Antagonistic via Mkp1 Protein and miR-1/206 MicroRNAs in Differentiating Myoblasts
2012
LUMPY: a probabilistic framework for structural variant discovery
2014
Vcfanno: fast, flexible annotation of genetic variants
2016
Breakpoint profiling of 64 cancer genomes reveals numerous complex rearrangements spawned by homology-independent mechanisms
2013
A map of constrained coding regions in the human genome
2018
Efficient genotype compression and analysis of large genetic-variation data sets
2015
Mapping and characterization of structural variation in 17,795 human genomes
2020 Nature
SpeedSeq: ultra-fast personal genome analysis and interpretation
2015
MicroRNA-378 Targets the Myogenic Repressor MyoR during Myoblast Differentiation
2011
Binary Interval Search: a scalable algorithm for counting interval intersections
2012
MUNC, a Long Noncoding RNA That Facilitates the Function of MyoD in Skeletal Myogenesis
2014