Ryan M. Layer

6.5k total citations · 1 hit paper
33 papers, 2.8k citations indexed

About

Ryan M. Layer is a scholar working on Molecular Biology, Genetics and Cancer Research. According to data from OpenAlex, Ryan M. Layer has authored 33 papers receiving a total of 2.8k indexed citations (citations by other indexed papers that have themselves been cited), including 27 papers in Molecular Biology, 18 papers in Genetics and 7 papers in Cancer Research. Recurrent topics in Ryan M. Layer's work include Genomics and Phylogenetic Studies (15 papers), Genomics and Rare Diseases (12 papers) and Genomic variations and chromosomal abnormalities (7 papers). Ryan M. Layer is often cited by papers focused on Genomics and Phylogenetic Studies (15 papers), Genomics and Rare Diseases (12 papers) and Genomic variations and chromosomal abnormalities (7 papers). Ryan M. Layer collaborates with scholars based in United States, United Kingdom and Norway. Ryan M. Layer's co-authors include Aaron R. Quinlan, Ira M. Hall, Colby Chiang, Anindya Dutta, Brent S. Pedersen, Jeffrey Gagan, Bijan K. Dey, Gábor Marth, Michael Lindberg and Gregory G. Faust and has published in prestigious journals such as Nature, Science and Nucleic Acids Research.

In The Last Decade

Ryan M. Layer

31 papers receiving 2.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

LUMPY: a probabilistic framework for structural variant discovery

2014 867 citations Ryan M. Layer, Colby Chiang et al. Genome biology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Ryan M. Layer United States	20	1.8k	1.2k	836	464	138	33	2.8k
Thomas Zichner Germany	12	1.4k 0.7×	760 0.6×	402 0.5×	396 0.9×	110 0.8×	19	2.2k
Hugo Y. K. Lam United States	23	1.7k 0.9×	927 0.8×	654 0.8×	499 1.1×	136 1.0×	32	2.4k
Adrian M. Stütz Germany	23	1.9k 1.0×	1.1k 0.9×	678 0.8×	659 1.4×	158 1.1×	44	3.3k
Andreas Schlattl Austria	10	1.2k 0.7×	757 0.6×	393 0.5×	359 0.8×	141 1.0×	16	1.8k
Michael Lawrence United States	10	2.9k 1.6×	812 0.7×	750 0.9×	654 1.4×	119 0.9×	24	4.3k
Tatiana Borodina Germany	14	2.5k 1.4×	539 0.4×	687 0.8×	431 0.9×	80 0.6×	25	3.3k
Colby Chiang United States	13	1.3k 0.7×	1.3k 1.0×	379 0.5×	489 1.1×	88 0.6×	16	2.2k
Semyon Kruglyak United States	13	2.0k 1.1×	1.1k 0.9×	452 0.5×	437 0.9×	208 1.5×	20	3.1k
Donna Karolchik United States	17	4.3k 2.4×	1.3k 1.0×	945 1.1×	693 1.5×	96 0.7×	21	5.3k
Fereydoun Hormozdiari United States	23	2.2k 1.2×	1.4k 1.2×	468 0.6×	712 1.5×	111 0.8×	42	3.1k

Countries citing papers authored by Ryan M. Layer

Since Specialization

Citations

This map shows the geographic impact of Ryan M. Layer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ryan M. Layer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ryan M. Layer more than expected).

Fields of papers citing papers by Ryan M. Layer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ryan M. Layer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ryan M. Layer. The network helps show where Ryan M. Layer may publish in the future.

Co-authorship network of co-authors of Ryan M. Layer

This figure shows the co-authorship network connecting the top 25 collaborators of Ryan M. Layer. A scholar is included among the top collaborators of Ryan M. Layer based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ryan M. Layer. Ryan M. Layer is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Layer, Ryan M., Douglas G. Scofield, Alexander Hayward, et al.. (2024). Calling Structural Variants with Confidence from Short-Read Data in Wild Bird Populations. Genome Biology and Evolution. 16(4). 3 indexed citations

Fosdick, Bailey K., et al.. (2024). Hypothesis generation for rare and undiagnosed diseases through clustering and classifying time-versioned biological ontologies. PLoS ONE. 19(12). e0309205–e0309205.

Dupuis, Josée, et al.. (2022). RAREsim: A simulation method for very rare genetic variants. The American Journal of Human Genetics. 109(4). 680–691.

Pedersen, Brent S., et al.. (2022). Searching thousands of genomes to classify somatic and novel structural variants using STIX. Nature Methods. 19(4). 445–448. 6 indexed citations

Belyeu, Jonathan R., et al.. (2021). Samplot: a platform for structural variant visual validation and automated filtering. Genome biology. 22(1). 161–161. 53 indexed citations

Carleton, Julia B., et al.. (2020). Regulatory sharing between estrogen receptor α bound enhancers. Nucleic Acids Research. 48(12). 6597–6610. 6 indexed citations

Abel, Haley, David E. Larson, Allison Regier, et al.. (2020). Mapping and characterization of structural variation in 17,795 human genomes. Nature. 583(7814). 83–89. 148 indexed citations

Larson, David E., Haley Abel, Colby Chiang, et al.. (2019). svtools: population-scale analysis of structural variation. Bioinformatics. 35(22). 4782–4787. 33 indexed citations

Belyeu, Jonathan R., T. Nicholas, Brent S. Pedersen, et al.. (2018). SV-plaudit: A cloud-based framework for manually curating thousands of structural variants. GigaScience. 7(7). 25 indexed citations

10.

Ostrander, Betsy, Russell J. Butterfield, Brent S. Pedersen, et al.. (2018). Whole-genome analysis for effective clinical diagnosis and gene discovery in early infantile epileptic encephalopathy. npj Genomic Medicine. 3(1). 22–22. 54 indexed citations

11.

Pedersen, Brent S., Ryan M. Layer, & Aaron R. Quinlan. (2016). Vcfanno: fast, flexible annotation of genetic variants. Genome biology. 17(1). 118–118. 92 indexed citations

12.

Layer, Ryan M. & Aaron R. Quinlan. (2015). A Parallel Algorithm for <formula><tex>$N$</tex></formula>-Way Interval Set Intersection. Proceedings of the IEEE. 105(3). 1–10. 4 indexed citations

13.

Chiang, Colby, Ryan M. Layer, Gregory G. Faust, et al.. (2015). SpeedSeq: ultra-fast personal genome analysis and interpretation. Nature Methods. 12(10). 966–968. 333 indexed citations

14.

Layer, Ryan M., et al.. (2015). Efficient genotype compression and analysis of large genetic-variation data sets. Nature Methods. 13(1). 63–65. 42 indexed citations

15.

Mueller, Adam C., Bijan K. Dey, Ryan M. Layer, et al.. (2014). MUNC, a Long Noncoding RNA That Facilitates the Function of MyoD in Skeletal Myogenesis. Molecular and Cellular Biology. 35(3). 498–513. 114 indexed citations

16.

Malhotra, Ankit, Michael Lindberg, Gregory G. Faust, et al.. (2013). Breakpoint profiling of 64 cancer genomes reveals numerous complex rearrangements spawned by homology-independent mechanisms. Genome Research. 23(5). 762–776. 124 indexed citations

17.

Sun, Dongxiao, Ryan M. Layer, Adam C. Mueller, et al.. (2013). Regulation of several androgen-induced genes through the repression of the miR-99a/let-7c/miR-125b-2 miRNA cluster in prostate cancer cells. Oncogene. 33(11). 1448–1457. 82 indexed citations

18.

Shibata, Yoshiyuki, Pankaj Kumar, Ryan M. Layer, et al.. (2012). Extrachromosomal MicroDNAs and Chromosomal Microdeletions in Normal Tissues. Science. 336(6077). 82–86. 221 indexed citations

19.

Gagan, Jeffrey, Bijan K. Dey, Ryan M. Layer, Zhen Yan, & Anindya Dutta. (2012). Notch3 and Mef2c Proteins Are Mutually Antagonistic via Mkp1 Protein and miR-1/206 MicroRNAs in Differentiating Myoblasts. Journal of Biological Chemistry. 287(48). 40360–40370. 75 indexed citations

20.

Gagan, Jeffrey, Bijan K. Dey, Ryan M. Layer, Zhen Yan, & Anindya Dutta. (2011). MicroRNA-378 Targets the Myogenic Repressor MyoR during Myoblast Differentiation. Journal of Biological Chemistry. 286(22). 19431–19438. 143 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact