Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
A general-purpose protein design framework based on mining sequence–structure relationships in known protein structures
2019
Generation of ordered protein assemblies using rigid three-body fusion
2021 StandoutNobel
DNA capture by a CRISPR-Cas9–guided adenine base editor
2020 StandoutScienceNobel
Exploiting conformational dynamics to modulate the function of designed proteins
2023 StandoutNobel
Origins of catalysis by computationally designed retroaldolase enzymes
2010 StandoutNobel
Computational design of closely related proteins that adopt two well-defined but structurally divergent folds
2020 StandoutNobel
Structure of the human TRPM4 ion channel in a lipid nanodisc
2017 StandoutScienceNobel
Structures of the CRISPR genome integration complex
2017 StandoutScienceNobel
Hallucinating symmetric protein assemblies
2022 StandoutScienceNobel
Accurate computational design of multipass transmembrane proteins
2018 StandoutScienceNobel
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
2020 StandoutScienceNobel
Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2
2020 StandoutScience
Rapid and automated design of two-component protein nanomaterials using ProteinMPNN
2024 StandoutNobel
Shape Context: A New Descriptor for Shape Matching and Object Recognition
2000
Unified Synthesis of Polycyclic Alkaloids by Complementary Carbonyl Activation**
2021 StandoutNobel
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
A Bayesian View on Cryo-EM Structure Determination
2011
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
Computational design of protein-small molecule interfaces
2013
Structure of a mammalian ryanodine receptor
2014 StandoutNatureNobel
Specificity prediction of adenylation domains in nonribosomal peptide synthetases (NRPS) using transductive support vector machines (TSVMs)
2005
cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination
2017 Standout
A Generic Program for Multistate Protein Design
2011
Open Babel: An open chemical toolbox
2011 Standout
Direct nitration and azidation of aliphatic carbons by an iron-dependent halogenase
2014
Irritant-evoked activation and calcium modulation of the TRPA1 receptor
2020 StandoutNatureNobel
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Protein WISDOM: A Workbench for <em>In silico</em> <em>De novo</em> Design of BioMolecules
2013
Expanding the Enzyme Universe: Accessing Non‐Natural Reactions by Mechanism‐Guided Directed Evolution
2015 StandoutNobel
Molecular Insights into the Biosynthesis of Guadinomine: A Type III Secretion System Inhibitor
2012 StandoutNobel
A Brief History of De Novo Protein Design: Minimal, Rational, and Computational
2021
Protein folding and de novo protein design for biotechnological applications
2013
A Fast Learning Algorithm for Deep Belief Nets
2006 StandoutNobel
Structure of the mammalian ribosomal pre-termination complex associated with eRF1•eRF3•GDPNP
2013 StandoutNobel
The coming of age of de novo protein design
2016 StandoutNatureNobel
Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
2020 Standout
Enantioselective Enzymes by Computational Design and In Silico Screening
2015 StandoutNobel
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
2021 StandoutNobel
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
2015 Standout
Computer-aided design of functional protein interactions
2009
CasX enzymes comprise a distinct family of RNA-guided genome editors
2019 StandoutNatureNobel
Multistate approaches in computational protein design
2012
Statistical and Computational Methods for Comparative Proteomic Profiling Using Liquid Chromatography-Tandem Mass Spectrometry
2005
MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
2008 Standout
De novo protein design by deep network hallucination
2021 StandoutNatureNobel
Transition-Path Theory and Path-Finding Algorithms for the Study of Rare Events
2008
Discovering Mountain Passes via Torchlight: Methods for the Definition of Reaction Coordinates and Pathways in Complex Macromolecular Reactions
2013
Computational structure-based redesign of enzyme activity
2009
De Novo Protein Design for Novel Folds Using Guided Conditional Wasserstein Generative Adversarial Networks
2020
Computer Simulation of Liquids
2017 Standout
Computation-Guided Backbone Grafting of a Discontinuous Motif onto a Protein Scaffold
2011 StandoutScienceNobel
Pore-forming activity and structural autoinhibition of the gasdermin family
2016 StandoutNature
Assemblages: Functional units formed by cellular phase separation
2014
Shape matching and object recognition using shape contexts
2002 Standout
Combinatorial methods for small-molecule placement in computational enzyme design
2006
Trajectories of the ribosome as a Brownian nanomachine
2014 StandoutNobel
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
2020 StandoutScience
Proteomics and the Analysis of Proteomic Data: An Overview of Current Protein‐Profiling Technologies
2005
Building Proteins in a Day: Efficient 3D Molecular Structure Estimation with Electron Cryomicroscopy
2016
Computational design of mechanically coupled axle-rotor protein assemblies
2022 StandoutScienceNobel
Computational Design of Multisubstrate Enzyme Specificity
2019
Structural insight into TRPV5 channel function and modulation
2019 StandoutNobel
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
Divergent Strategy in Natural Product Total Synthesis
2018
Computational design gains momentum in enzyme catalysis engineering
2013
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
Liquid phase condensation in cell physiology and disease
2017 StandoutScience
Enzyme-Controlled Nitrogen-Atom Transfer Enables Regiodivergent C–H Amination
2014 StandoutNobel
Chemical Glycoproteomics
2016 StandoutNobel
Computational design of a red fluorophore ligase for site-specific protein labeling in living cells
2014 StandoutNobel
Works of Ryan Lilien being referenced
osprey
2013
Optimization and dynamics of protein–protein complexes using B‐splines
2004
The minimized dead‐end elimination criterion and its application to protein redesign in a hybrid scoring and search algorithm for computing partition functions over molecular ensembles
2008
Allosteric Inhibition of the Protein-Protein Interaction between the Leukemia-Associated Proteins Runx1 and CBFβ
2007
A Structure-Based Approach for Mapping Adverse Drug Reactions to the Perturbation of Underlying Biological Pathways
2010
Network-analysis-guided synthesis of weisaconitine D and liljestrandinine
2015 Nature
Probabilistic Disease Classification of Expression-Dependent Proteomic Data from Mass Spectrometry of Human Serum
2003
A Novel Ensemble-Based Scoring and Search Algorithm for Protein Redesign and Its Application to Modify the Substrate Specificity of the Gramicidin Synthetase A Phenylalanine Adenylation Enzyme
2005
Improved Pruning algorithms and Divide-and-Conquer strategies for Dead-End Elimination, with application to protein design
2006
View-based recognition using an eigenspace approximation to the Hausdorff measure
1999
Redesigning the PheA Domain of Gramicidin Synthetase Leads to a New Understanding of the Enzyme's Mechanism and Selectivity
2006
The protein–small-molecule database, a non-redundant structural resource for the analysis of protein-ligand binding
2009
A Bayesian method for 3D macromolecular structure inference using class average images from single particle electron microscopy
2010