Citation Impact
Citing Papers
Confirmation of intersubunit connectivity and topology of designed protein complexes by native MS
2018 StandoutNobel
Dissecting Therapeutic Resistance to RAF Inhibition in Melanoma by Tumor Genomic Profiling
2011
Noncovalent Wild-type–Sparing Inhibitors of EGFR T790M
2012
Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in EGFR-Mutant Lung Cancer: Distinct Natural History of Patients with Tumors Harboring the T790M Mutation
2010
Noninvasive Detection of Response and Resistance in EGFR -Mutant Lung Cancer Using Quantitative Next-Generation Genotyping of Cell-Free Plasma DNA
2014
Clinical, Pathologic, and Biologic Features Associated with BRAF Mutations in Non–Small Cell Lung Cancer
2013
EGFR Mutations and Resistance to Irreversible Pyrimidine-Based EGFR Inhibitors
2015
The Allelic Context of the C797S Mutation Acquired upon Treatment with Third-Generation EGFR Inhibitors Impacts Sensitivity to Subsequent Treatment Strategies
2015
The diverse and expanding role of mass spectrometry in structural and molecular biology
2016
Inference and analysis of cell-cell communication using CellChat
2021 Standout
Discovery of archaeal fusexins homologous to eukaryotic HAP2/GCS1 gamete fusion proteins
2022 StandoutNobel
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Mechanisms of SARS-CoV-2 entry into cells
2021 Standout
A view on drug resistance in cancer
2019 StandoutNature
Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial
2015 Standout
Liquid biopsy: monitoring cancer-genetics in the blood
2013
Small-Molecule Inhibition of c-MYC:MAX Leucine Zipper Formation Is Revealed by Ion Mobility Mass Spectrometry
2012 StandoutNobel
mRNA-based therapeutics — developing a new class of drugs
2014 StandoutNobel
Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
2012 Standout
Contextual determinants of TGFβ action in development, immunity and cancer
2018
The biology and management of non-small cell lung cancer
2018 StandoutNature
Acquired EGFR C797S mutation mediates resistance to AZD9291 in non–small cell lung cancer harboring EGFR T790M
2015
Transforming Growth Factor-β Signaling in Immunity and Cancer
2019 Standout
Integrating liquid biopsies into the management of cancer
2017
The Evolving War on Cancer
2011
Cutting-edge mass spectrometry methods for the multi-level structural characterization of antibody-drug conjugates
2015
Cancer drug resistance: an evolving paradigm
2013 Standout
O-Pair Search with MetaMorpheus for O-glycopeptide characterization
2020 StandoutNobel
Radiomics: Images Are More than Pictures, They Are Data
2015 Standout
Ion mobility mass spectrometry for peptide analysis
2011
Osimertinib or Platinum–Pemetrexed in EGFR T790M–Positive Lung Cancer
2016 Standout
Influence of tumour micro-environment heterogeneity on therapeutic response
2013 StandoutNature
Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer
2013 Standout
HCV E2 core structures and mAbs: something is still missing
2014
Hierarchical Modeling of Activation Mechanisms in the ABL and EGFR Kinase Domains: Thermodynamic and Mechanistic Catalysts of Kinase Activation by Cancer Mutations
2009
The unexpected structures of hepatitis C virus envelope proteins
2017
A Strategy for O-Glycoproteomics of Enveloped Viruses—the O-Glycoproteome of Herpes Simplex Virus Type 1
2015
Hepatitis C Virus (HCV) Infection May Elicit Neutralizing Antibodies Targeting Epitopes Conserved in All Viral Genotypes
2009
Targeted covalent drugs of the kinase family
2010
Lung cancer: current therapies and new targeted treatments
2016 Standout
CRISPR-Barcoding for Intratumor Genetic Heterogeneity Modeling and Functional Analysis of Oncogenic Driver Mutations
2016
Rapid online buffer exchange for screening of proteins, protein complexes and cell lysates by native mass spectrometry
2020 StandoutNobel
Conformational changes in the G protein Gs induced by the β2 adrenergic receptor
2011 StandoutNatureNobel
TGF-β1 Signaling and Tissue Fibrosis
2017
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Tumour heterogeneity and cancer cell plasticity
2013 StandoutNature
Liquid biopsies come of age: towards implementation of circulating tumour DNA
2017 Standout
A Milieu Molecule for TGF-β Required for Microglia Function in the Nervous System
2018
Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
2020 Standout
Emerging Role of mTOR in the Response to Cancer Therapeutics
2016
Brigatinib combined with anti-EGFR antibody overcomes osimertinib resistance in EGFR-mutated non-small-cell lung cancer
2017
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage
2014 Standout
Oxidative Stress in Cancer
2020 Standout
Structure–function analysis of hepatitis C virus envelope glycoproteins E1 and E2
2014
Strategies and challenges for the next generation of antibody–drug conjugates
2017 Standout
The PI3K Pathway in Human Disease
2017 Standout
Acquired resistance to TKIs in solid tumours: learning from lung cancer
2014
VEGF in Signaling and Disease: Beyond Discovery and Development
2019 Standout
Functional expression and characterization of the envelope glycoprotein E1E2 heterodimer of hepatitis C virus
2019 StandoutNobel
A Noninvasive System for Monitoring Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors with Plasma DNA
2011
Cryo-EM Reveals Integrin-Mediated TGF-β Activation without Release from Latent TGF-β
2020
Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer
2010
Capitalizing on knowledge of hepatitis C virus neutralizing epitopes for rational vaccine design
2015
Application of electron transfer dissociation (ETD) for the analysis of posttranslational modifications
2008
Hepatitis C Virus RNA Functionally Sequesters miR-122
2015 StandoutNobel
Tumor-infiltrating regulatory T cells as targets of cancer immunotherapy
2023 StandoutNobel
Characterization of Therapeutic Antibodies and Related Products
2012
Single nucleotide editing without DNA cleavage using CRISPR/Cas9‐deaminase in the sea urchin embryo
2017
Metal Catalysts for Heterogeneous Catalysis: From Single Atoms to Nanoclusters and Nanoparticles
2018 Standout
Selective Targeting of Integrin αvβ8 by a Highly Active Cyclic Peptide
2019
Recombinant Hepatitis C Virus Envelope Glycoprotein Vaccine Elicits Antibodies Targeting Multiple Epitopes on the Envelope Glycoproteins Associated with Broad Cross-Neutralization
2014 StandoutNobel
Structural basis of latent TGF-β1 presentation and activation by GARP on human regulatory T cells
2018 Science
Enzymatic Oxidation of Methane
2015
Identification of New Functional Regions in Hepatitis C Virus Envelope Glycoprotein E2
2010
Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus
2012 StandoutNobel
Electron-Based Dissociation Is Needed for O-Glycopeptides Derived from OpeRATOR Proteolysis
2020 StandoutNobel
A development that may evolve into a revolution in medicine: mRNA as the basis for novel, nucleotide-based vaccines and drugs
2013
A Recombinant Hepatitis C Virus Genotype 1a E1/E2 Envelope Glycoprotein Vaccine Elicits Antibodies That Differentially Neutralize Closely Related 2a Strains through Interactions of the N-Terminal Hypervariable Region 1 of E2 with Scavenger Receptor B1
2019 StandoutNobel
Computational Prediction of the Heterodimeric and Higher-Order Structure of gpE1/gpE2 Envelope Glycoproteins Encoded by Hepatitis C Virus
2017 StandoutNobel
Piezo1 channels restrain regulatory T cells but are dispensable for effector CD4 + T cell responses
2021 Standout
Association Between Plasma Genotyping and Outcomes of Treatment With Osimertinib (AZD9291) in Advanced Non–Small-Cell Lung Cancer
2016
Cutting‐edge mass spectrometry characterization of originator, biosimilar and biobetter antibodies
2015
Cysteine-Mediated Redox Signaling: Chemistry, Biology, and Tools for Discovery
2013
The Role of Electron Transfer Dissociation in Modern Proteomics
2017
Role of N-Linked Glycans in the Functions of Hepatitis C Virus Envelope Proteins Incorporated into Infectious Virions
2010
Alkane Oxidation: Methane Monooxygenases, Related Enzymes, and Their Biomimetics
2017
Cancer Genome Landscapes
2013 StandoutScience
N501Y mutation of spike protein in SARS-CoV-2 strengthens its binding to receptor ACE2
2021
Bioinspired Metal–Organic Framework Catalysts for Selective Methane Oxidation to Methanol
2018 StandoutNobel
Native Folding of a Recombinant gpE1/gpE2 Heterodimer Vaccine Antigen from a Precursor Protein Fused with Fc IgG
2016 StandoutNobel
Specificity, versatility, and control of TGF-β family signaling
2019
Analysis of Protein Conformation and Dynamics by Hydrogen/Deuterium Exchange MS
2009
Mannan binding lectin-associated serine protease 1 is induced by hepatitis C virus infection and activates human hepatic stellate cells
2013
Mutations in Hepatitis C Virus E2 Located outside the CD81 Binding Sites Lead to Escape from Broadly Neutralizing Antibodies but Compromise Virus Infectivity
2009 StandoutNobel
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
2016 StandoutNobel
A tumor-specific mechanism of T reg enrichment mediated by the integrin αvβ8
2021
Circumventing Cancer Drug Resistance in the Era of Personalized Medicine
2012
“Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates
2017 StandoutNobel
Modified E2 Glycoprotein of Hepatitis C Virus Enhances Proinflammatory Cytokines and Protective Immune Response
2022 StandoutNobel
Hypervariable region 1 and N-linked glycans of hepatitis C regulate virion neutralization by modulating envelope conformations
2019
Chemical Glycoproteomics
2016 StandoutNobel
Works of Roxana E. Iacob being referenced
Tolloid cleavage activates latent GDF8 by priming the pro‐complex for dissociation
2018
Structure and Dynamic Regulation of Abl Kinases*
2013
Novel mutant-selective EGFR kinase inhibitors against EGFR T790M
2009 StandoutNature
Electron Transfer Control in Soluble Methane Monooxygenase
2014
Force interacts with macromolecular structure in activation of TGF-β
2017 Nature
Structural elucidation of critical residues involved in binding of human monoclonal antibodies to hepatitis C virus E2 envelope glycoprotein
2008
Enhanced SH3/Linker Interaction Overcomes Abl Kinase Activation by Gatekeeper and Myristic Acid Binding Pocket Mutations and Increases Sensitivity to Small Molecule Inhibitors*
2013
Ion mobility adds an additional dimension to mass spectrometric analysis of solution‐phase hydrogen/deuterium exchange
2008
Hydrogen/deuterium exchange mass spectrometry for probing higher order structure of protein therapeutics: methodology and applications
2013
Investigating Monoclonal Antibody Aggregation Using a Combination of H/DX-MS and Other Biophysical Measurements
2013
Conformational disturbance in Abl kinase upon mutation and deregulation
2009
Mass spectrometric characterization of glycosylation of hepatitis C virus E2 envelope glycoprotein reveals extended microheterogeneity of N-glycans
2007
The Influence of Adnectin Binding on the Extracellular Domain of Epidermal Growth Factor Receptor
2014
Hydrogen Exchange Mass Spectrometry: Are We Out of the Quicksand?
2012
Fusion surface structure, function, and dynamics of gamete fusogen HAP2
2018
Applications of Hydrogen/Deuterium Exchange MS from 2012 to 2014
2014