Standout Papers
- Computational Enzyme Design (2013)
- A Pareto-Optimal Refinement Method for Protein Design Scaffolds (2013)
- Scoring functions for protein–protein interactions (2013)
- Engineering an allosteric transcription factor to respond to new ligands (2015)
- Computerbasiertes Enzymdesign (2013)
- Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1 (2021)
Citation Impact
Citing Papers
Confirmation of intersubunit connectivity and topology of designed protein complexes by native MS
2018 StandoutNobel
Anti-Markovnikov alkene oxidation by metal-oxo–mediated enzyme catalysis
2017 StandoutScienceNobel
Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation
2015 StandoutNobel
An enumerative algorithm for de novo design of proteins with diverse pocket structures
2020 StandoutNobel
Evolution of a highly active and enantiospecific metalloenzyme from short peptides
2018 Science
A general-purpose protein design framework based on mining sequence–structure relationships in known protein structures
2019
Removing T-cell epitopes with computational protein design
2014 StandoutNobel
Principles for designing proteins with cavities formed by curved β sheets
2017 StandoutScienceNobel
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
De novo design of self-assembling helical protein filaments
2018 StandoutScienceNobel
Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion
2020 StandoutNobel
Computational design of closely related proteins that adopt two well-defined but structurally divergent folds
2020 StandoutNobel
How directed evolution reshapes the energy landscape in an enzyme to boost catalysis
2020 Science
De novo design of a transmembrane Zn 2+ -transporting four-helix bundle
2014 Science
A designed supramolecular protein assembly with in vivo enzymatic activity
2014 Science
Hallucinating symmetric protein assemblies
2022 StandoutScienceNobel
Accurate computational design of multipass transmembrane proteins
2018 StandoutScienceNobel
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
A suite of designed protein cages using machine learning and protein fragment-based protocols
2024
Highly active enzymes by automated combinatorial backbone assembly and sequence design
2018
Precision is essential for efficient catalysis in an evolved Kemp eliminase
2013 Nature
Control of repeat-protein curvature by computational protein design
2015 StandoutNobel
Modular and tunable biological feedback control using a de novo protein switch
2019 StandoutNatureNobel
Computationally designed libraries for rapid enzyme stabilization
2014 StandoutNobel
Installing hydrolytic activity into a completely de novo protein framework
2016
Evolution of dynamical networks enhances catalysis in a designer enzyme
2021
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Directed enzyme evolution: beyond the low-hanging fruit
2012
The role of distant mutations and allosteric regulation on LovD active site dynamics
2014
Computational Library Design for Increasing Haloalkane Dehalogenase Stability
2014 StandoutNobel
De novo design of luciferases using deep learning
2023 StandoutNatureNobel
Natural‐Product Sugar Biosynthesis and Enzymatic Glycodiversification
2008
Expanding the Enzyme Universe: Accessing Non‐Natural Reactions by Mechanism‐Guided Directed Evolution
2015 StandoutNobel
OptZyme: Computational Enzyme Redesign Using Transition State Analogues
2013
Catalytic efficiency of designed catalytic proteins
2014
Advances in protein structure prediction and design
2019
Rational design of α-helical tandem repeat proteins with closed architectures
2015 StandoutNatureNobel
Genetically programmed chiral organoborane synthesis
2017 StandoutNatureNobel
Efficient Lewis acid catalysis of an abiological reaction in a de novo protein scaffold
2021
The coming of age of de novo protein design
2016 StandoutNatureNobel
Design of biologically active binary protein 2D materials
2021 StandoutNatureNobel
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
A Promiscuous De Novo Retro‐Aldolase Catalyzes Asymmetric Michael Additions via Schiff Base Intermediates
2015
A designer enzyme for hydrazone and oxime formation featuring an unnatural catalytic aniline residue
2018
Enantioselective Enzymes by Computational Design and In Silico Screening
2015 StandoutNobel
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
De novo design of bioactive protein switches
2019 StandoutNatureNobel
De novo design of a four-fold symmetric TIM-barrel protein with atomic-level accuracy
2015 StandoutNobel
De novo protein design: how do we expand into the universe of possible protein structures?
2015
Exploring the repeat protein universe through computational protein design
2015 StandoutNatureNobel
Protein sequence design with a learned potential
2022
Recent achievments in the design and engineering of artificial metalloenzymes
2014
Protein Engineering for Improving and Diversifying Natural Product Biosynthesis
2020
Simple yet functional phosphate-loop proteins
2018 StandoutNobel
Design and evolution of enzymes for non-natural chemistry
2017 StandoutNobel
Accurate design of megadalton-scale two-component icosahedral protein complexes
2016 StandoutScienceNobel
Computational design of a homotrimeric metalloprotein with a trisbipyridyl core
2016 StandoutNobel
The ONIOM Method and Its Applications
2015
Directed Evolution of a Designer Enzyme Featuring an Unnatural Catalytic Amino Acid
2018
Catalytic iron-carbene intermediate revealed in a cytochrome c carbene transferase
2018 StandoutNobel
Supramolecular Assembly of Artificial Metalloenzymes Based on the Dimeric Protein LmrR as Promiscuous Scaffold
2015
De novo design of modular protein hydrogels with programmable intra- and extracellular viscoelasticity
2024 StandoutNobel
De novo design of protein homo-oligomers with modular hydrogen-bond network–mediated specificity
2016 StandoutScienceNobel
Computational Prediction of the Heterodimeric and Higher-Order Structure of gpE1/gpE2 Envelope Glycoproteins Encoded by Hepatitis C Virus
2017 StandoutNobel
Active Site Plasticity of a Computationally Designed Retro‐Aldolase Enzyme
2014 StandoutNobel
Sampling and energy evaluation challenges in ligand binding protein design
2017 StandoutNobel
Enzymatic construction of highly strained carbocycles
2018 StandoutScienceNobel
Directed Evolution of Protein Catalysts
2018
Fast Knoevenagel Condensations Catalyzed by an Artificial Schiff-Base-Forming Enzyme
2016
The Crucial Role of Methodology Development in Directed Evolution of Selective Enzymes
2019
Computational design of mechanically coupled axle-rotor protein assemblies
2022 StandoutScienceNobel
Biocatalysis in Organic Chemistry and Biotechnology: Past, Present, and Future
2013
Parallel Screening for Rapid Identification of Orthogonal Bioluminescent Tools
2017
Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts
2015 StandoutNobel
Chemoenzymatic elaboration of monosaccharides using engineered cytochrome P450 BM3 demethylases
2009 StandoutNobel
Improving the Catalytic Performance of an Artificial Metalloenzyme by Computational Design
2015 StandoutNobel
A Promiscuous De Novo Retro‐Aldolase Catalyzes Asymmetric Michael Additions via Schiff Base Intermediates
2015
Essentials of de novo protein design: Methods and applications
2018
Integration of the Rosetta suite with the python software stack via reproducible packaging and core programming interfaces for distributed simulation
2019
Automating human intuition for protein design
2013 StandoutNobel
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
Impact of scaffold rigidity on the design and evolution of an artificial Diels-Alderase
2014 StandoutNobel
Engineering of Kuma030: A Gliadin Peptidase That Rapidly Degrades Immunogenic Gliadin Peptides in Gastric Conditions
2015 StandoutNobel
Artificial Metalloenzymes and Metallopeptide Catalysts for Organic Synthesis
2013
Design of ordered two-dimensional arrays mediated by noncovalent protein-protein interfaces
2015 StandoutScienceNobel
Works of Rocco Moretti being referenced
Expanding the Nucleotide and Sugar 1-Phosphate Promiscuity of Nucleotidyltransferase RmlA via Directed Evolution
2011
Computational Enzyme Design
2013 StandoutNobel
Engineering an allosteric transcription factor to respond to new ligands
2015 StandoutNobel
A Pareto-Optimal Refinement Method for Protein Design Scaffolds
2013 StandoutNobel
Enhancing the Latent Nucleotide Triphosphate Flexibility of the Glucose-1-phosphate Thymidylyltransferase RmlA
2007
Protocols for Molecular Modeling with Rosetta3 and RosettaScripts
2016
Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1
2021 StandoutNobel
Web‐accessible molecular modeling with Rosetta: The Rosetta Online Server that Includes Everyone (ROSIE)
2017
Computerbasiertes Enzymdesign
2013 StandoutNobel