Citation Impact

Citing Papers

Systematic discovery of antiphage defense systems in the microbial pangenome
2018 Science
Structure of the human TRPM4 ion channel in a lipid nanodisc
2017 StandoutScienceNobel
Reactive Oxygen Species in Inflammation and Tissue Injury
2013 Standout
Dual Role of CD38 in Microglial Activation and Activation-Induced Cell Death
2008
The Pseudomonas aeruginosa accessory genome elements influence virulence towards Caenorhabditis elegans
2019 StandoutNobel
Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein
2014 Standout
Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis
2015 Standout
Extracellular NAD+Is an Agonist of the Human P2Y11Purinergic Receptor in Human Granulocytes
2006
NAD+ and NADH in cellular functions and cell death
2006
Molecular Understanding and Modern Application of Traditional Medicines: Triumphs and Trials
2007 Standout
Nucleotide signalling during inflammation
2014 StandoutNature
TRPM2 Channel in Microglia as a New Player in Neuroinflammation Associated With a Spectrum of Central Nervous System Pathologies
2019
TRPV3 in keratinocytes transmits temperature information to sensory neurons via ATP
2009 StandoutNobel
Orthosteric and allosteric binding sites of P2X receptors
2008
Irritant-evoked activation and calcium modulation of the TRPA1 receptor
2020 StandoutNatureNobel
Clemastine Potentiates the Human P2X7 Receptor by Sensitizing It to Lower ATP Concentrations
2011
Transient receptor potential channels: targeting pain at the source
2008 StandoutNobel
Cyclic ADP‐ribose is a second messenger in the lipopolysaccharide‐stimulated activation of murine N9 microglial cell line
2006
Ectonucleotidases as Regulators of Purinergic Signaling in Thrombosis, Inflammation, and Immunity
2011
Renal and Extrarenal Effects of Gum Arabic (Acacia Senegal) - What Can be Learned from Animal Experiments?
2013 Standout
The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept
2007 Standout
TRPM2 activation by cyclic ADP‐ribose at body temperature is involved in insulin secretion
2006
From chills to chilis: mechanisms for thermosensation and chemesthesis via thermoTRPs
2007 StandoutNobel
IL-6 as a keystone cytokine in health and disease
2015 Standout
Significance of P2X7 Receptor Variants to Human Health and Disease
2011
The P2X7 Receptor Channel: Recent Developments and the Use of P2X7 Antagonists in Models of Disease
2014
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
2016 Standout
SGK3 Regulates Ca2+Entry and Migration of Dendritic Cells
2012
Impact of Ectoenzymes on P2 and P1 Receptor Signaling
2011
Molecular Mechanism of ADP-Ribose Hydrolysis By Human NUDT5 From Structural and Kinetic Studies
2008
TRPM2
2014
Oxidative Stress in Cancer
2020 Standout
Activation and Regulation of Purinergic P2X Receptor Channels
2011
Copper(I)‐Catalyzed Cycloaddition of Organic Azides and 1‐Iodoalkynes
2009 StandoutNobel
Species Specificity of ADAM10 and ADAM17 Proteins in Interleukin-6 (IL-6) Trans-signaling and Novel Role of ADAM10 in Inducible IL-6 Receptor Shedding
2011
CD39 and CD73 in immunity and inflammation
2013 Standout
The functional network of ion channels in T lymphocytes
2009
Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain
2010 StandoutNobel
NAD+ and NADH in brain functions, brain diseases and brain aging
2006
Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond
2019 Standout
Neutrophil TRPM2 channels are implicated in the exacerbation of myocardial ischaemia/reperfusion injury
2012
Reactive oxygen species, cellular redox systems, and apoptosis
2010 Standout
Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium
2018 Nature
Single domain antibodies: promising experimental and therapeutic tools in infection and immunity
2009
P2X receptors: dawn of the post-structure era
2009
Characterisation of the R276A gain-of-function mutation in the ectodomain of murine P2X7
2009
Metabolic adaptation of cancer and immune cells mediated by hypoxia-inducible factors
2018 StandoutNobel
Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?
2020 Standout
Second messenger function and the structure–activity relationship of cyclic adenosine diphosphoribose (cADPR)
2005
NAD + /NADH and NADP + /NADPH in Cellular Functions and Cell Death: Regulation and Biological Consequences
2007 Standout
Structure of a TRPM2 channel in complex with Ca2+ explains unique gating regulation
2018
Ligand-Gated Ion Channels: New Insights into Neurological Disorders and Ligand Recognition
2012
Dynamics of NAD-metabolism: everything but constant
2015
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Targeting the Receptor for Advanced Glycation Endproducts (RAGE): A Medicinal Chemistry Perspective
2017 Standout
TRP channels and pain
2007
Role of H2O2-activated TRPM2 calcium channel in oxidant-induced endothelial injury
2009
Neue Ziele für die Photopharmakologie
2016 StandoutNobel
Fluorescence Lifetime Measurements and Biological Imaging
2010 Standout
Ion Channels in Innate and Adaptive Immunity
2015
DAMP-sensing receptors in sterile inflammation and inflammatory diseases
2019 Standout
Piezo1 channels restrain regulatory T cells but are dispensable for effector CD4 + T cell responses
2021 Standout
Migration of Dendritic Cell Subsets and their Precursors
2007
Transient Receptor Potential Melastatin Subfamily Member 2 Cation Channel Regulates Detrimental Immune Cell Invasion in Ischemic Stroke
2014
Main cellular redox couples
2015
Structural Isosteres of Phosphate Groups in the Protein Data Bank
2017
Copper(I)‐Catalyzed Cycloaddition of Organic Azides and 1‐Iodoalkynes
2009 StandoutNobel
CD38 expression in early B‐cell precursors contributes to extracellular signal‐regulated kinase‐mediated apoptosis
2014
Drosophila homologue of Diaphanous 1 (DIAPH1) controls the metastatic potential of colon cancer cells by regulating microtubule-dependent adhesion
2015
Receptors for Purines and Pyrimidines
2012 Standout
Emerging Targets in Photopharmacology
2016 StandoutNobel
Endogenous ADP-ribose enables calcium-regulated cation currents through TRPM2 channels in neutrophil granulocytes
2006
A Convenient Preparation of 5-Iodo-1,4-disubstituted-1,2,3-triazole: Multicomponent One-Pot Reaction of Azide and Alkyne Mediated by CuI−NBS
2008
TRP Channels
2007 Standout
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release
2017 StandoutNobel
Nanobodies: Natural Single-Domain Antibodies
2013 Standout
Physiology of Microglia
2011 Standout
Photochemical Properties and Reactivity of a Ru Compound Containing an NAD/NADH-Functionalized 1,10-Phenanthroline Ligand
2016 StandoutNobel
The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting
2013 Standout

Works of Ralf Fliegert being referenced

Chemotaxis of Mouse Bone Marrow Neutrophils and Dendritic Cells Is Controlled by ADP-Ribose, the Major Product Generated by the CD38 Enzyme Reaction
2007
Activation of the P2X7 ion channel by soluble and covalently bound ligands
2009
Inositol 1,4,5-Trisphosphate 3-Kinase-A Is a New Cell Motility-promoting Protein That Increases the Metastatic Potential of Tumor Cells by Two Functional Activities
2009
Alternative Splicing of the N-Terminal Cytosolic and Transmembrane Domains of P2X7 Controls Gating of the Ion Channel by ADP-Ribosylation
2012
Activation of T Cell Calcium Influx by the Second Messenger ADP-ribose
2005
Ligand-induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg1433 and Tyr1349
2017
ADP‐ribosylation at R125 gates the P2X7 ion channel by presenting a covalent ligand to its nucleotide binding site
2007
Regulation of calcium signalling by adenine-based second messengers
2007
Synthesis and Biological Evaluation of Novel Membrane-Permeant Cyclic ADP-Ribose Mimics:  N-[(5‘ ‘-O-Phosphorylethoxy)methyl]-5‘-O-phosphorylinosine 5‘,5‘ ‘-Cyclicpyrophosphate (cIDPRE) and 8-Substituted Derivatives
2004
Adenine Dinucleotide Second Messengers and T-lymphocyte Calcium Signaling
2013
Structure–Activity Relationship of Adenosine 5′-diphosphoribose at the Transient Receptor Potential Melastatin 2 (TRPM2) Channel: Rational Design of Antagonists
2013
Rankless by CCL
2026