Standout Papers
Citation Impact
Citing Papers
Growth factor‐stimulated MAP kinase induces rapid retrophosphorylation and inhibition of MAP kinase kinase (MEK1)
1994
Targeting of Diacylglycerol Degradation to M1 Muscarinic Receptors by ß-Arrestins
2007 StandoutScienceNobel
Spinophilin Blocks Arrestin Actions in Vitro and in Vivo at G Protein-Coupled Receptors
2004 StandoutScienceNobel
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
Targeting of Cyclic AMP Degradation to β 2 -Adrenergic Receptors by β-Arrestins
2002 StandoutScienceNobel
The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
2013 StandoutScienceNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
The Mouse B-raf Gene Encodes Multiple Protein Isoforms with Tissue-specific Expression
1995
Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1
1993 Nature
Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate
1993
SOS Phosphorylation and Disassociation of the Grb2-SOS Complex by the ERK and JNK Signaling Pathways
1996
Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A
1997 StandoutNatureNobel
MAP kinase kinase from rabbit skeletal muscle A novel dual specificity enzyme showing homology to yeast protein kinases involved in pheromone‐dependent signal transduction
1992
Nerve Growth Factor-mediated Activation of the Mitogen-activated Protein (MAP) Kinase Cascade Involves a Signaling Complex Containing B-Raf and HSP90
1996
Recent progress in characterization of protein kinase cascades for phosphorylation of ribosomal protein S6
1991
Regulation of protein kinase cascades by protein phosphatase 2A
1999
Signaling Networks
2000
Raf-1 activates MAP kinase-kinase
1992 Nature
Rapid deactivation of MAP kinase in PC12 cells occurs independently of induction of phosphatase MKP‐1
1994
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
2006 StandoutNature
Caenorhabditis elegans pathways that surveil and defend mitochondria
2014 StandoutNatureNobel
The complexity of Raf-1 regulation
1997
Crystal structures of the myristylated catalytic subunit of cAMP‐dependent protein kinase reveal open and closed conformations
1993
On target with a new mechanism for the regulation of protein phosphorylation
1993
MAP kinase kinase kinase, MAP kinase kinase and MAP kinase
1994
The mitogen-activated protein kinase activator
1992
ERKs: A family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF
1991 Standout
Requirement of Phosphatidylinositol 3-Kinase Activity for Bradykinin Stimulation of NF-κB Activation in Cultured Human Epithelial Cells
1999
Mammalian Ras interacts directly with the serine/threonine kinase raf
1993 Standout
A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
1996 StandoutNatureNobel
Raf meets Ras: completing the framework of a signal transduction pathway
1994
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
1995 StandoutNature
Neuronal Microtubule-associated Protein 2D Is a Dual A-kinase Anchoring Protein Expressed in Rat Ovarian Granulosa Cells
2004
Mitogen-activated protein kinase pathways
1997 Standout
Regulation of Ras-mediated signalling: more than one way to skin a cat
1995
ERK2 Mitogen-activated Protein Kinase Binding, Phosphorylation, and Regulation of the PDE4D cAMP-specific Phosphodiesterases
2000
Complementation of byrl in fission yeast by mammalian MAP kinase kinase requires coexpression of Raf kinase
1993 Nature
Purification of a Ras-dependent Mitogen-activated Protein Kinase Kinase Kinase from Bovine Brain Cytosol and Its Identification as a Complex of B-Raf and 14-3-3 Proteins
1995
Ras-dependent growth factor regulation of MEK kinase in PC12 cells
1994 Science
The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain
1993
Dual Effect of β-Adrenergic Receptors on Mitogen-activated Protein Kinase
1995
Interaction of 14-3-3 with Signaling Proteins Is Mediated by the Recognition of Phosphoserine
1996 Standout
Visualizing the mechanical activation of Src
2005 StandoutNatureNobel
Involvement of p21ras in activation of extracellular signal-regulated kinase 2
1992 Nature
Different Effects of Various Phospholipids on Ki-Ras-, Ha-Ras-, and Rap1B-induced B-Raf Activation
1996
Cyclic AMP-dependent Activation of Rap1b
1995
Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
1994 Standout
TSC2 regulates VEGF through mTOR-dependent and -independent pathways
2003 StandoutNobel
Activation of the Raf/MAP kinase cascade by the Ras-related protein TC21 is required for the TC21-mediated transformation of NIH 3T3 cells
1999
Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras
1994
Functional interactions between the gut microbiota and host metabolism
2012 StandoutNature
Essential Role for G Protein-coupled Receptor Endocytosis in the Activation of Mitogen-activated Protein Kinase
1998 StandoutNobel
Biochemical Analysis of MEK Activation in NIH3T3 Fibroblasts
1995
Protein kinases and phosphatases: The Yin and Yang of protein phosphorylation and signaling
1995 Standout
Sequential protein kinase reactions controlling cell growth and differentiation
1994
Activation of Raf-1 by 14-3-3 proteins
1994 Nature
Kinase cascade conserved
1992
The Recruitment of Raf-1 to Membranes Is Mediated by Direct Interaction with Phosphatidic Acid and Is Independent of Association with Ras
2000
Mitogenic Signaling via G Protein-Coupled Receptors
1996 StandoutNobel
Purification and characterisation of the insulin‐stimulated protein kinase from rabbit skeletal muscle; close similarity to S6 kinase II
1991
Extracellular signals and reversible protein phosphorylation: What to Mek of it all
1993
Activation of Brain B-Raf Protein Kinase by Rap1B Small GTP-binding Protein
1996
Serine Phosphorylation of Death Agonist BAD in Response to Survival Factor Results in Binding to 14-3-3 Not BCL-XL
1996 Standout
The protein kinase KSR interacts with 14-3-3 protein and Raf
1997
Down-regulation of Cholesterol 7α-Hydroxylase (CYP7A1) Gene Expression by Bile Acids in Primary Rat Hepatocytes Is Mediated by the c-Jun N-terminal Kinase Pathway
2001
A conserved kinase cascade for MAP kinase activation in yeast
1993
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
The MAP kinase cascade is essential for diverse signal transduction pathways
1993
cAMP Activates MAP Kinase and Elk-1 through a B-Raf- and Rap1-Dependent Pathway
1997 Standout
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
Protein kinase Cα activates RAF-1 by direct phosphorylation
1993 Nature
β2-Adrenergic Receptor Activates Extracellular Signal-regulated Kinases (ERKs) via the Small G Protein Rap1 and the Serine/Threonine Kinase B-Raf
2000
Ras-dependent activation of MAP kinase pathway mediated by G-protein βγ subunits
1994 Nature
Signal integration at the level of protein kinases, protein phosphatases and their substrates
1992
Systematic analysis of genes required for synapse structure and function
2005 StandoutNatureNobel
cAMP-mediated Growth Inhibition in Fibroblasts Is Not Mediated via Mitogen-activated Protein (MAP) Kinase (ERK) Inhibition
1996
Differentiation of PC12 cells in response to a cAMP analogue is accompanied by sustained activation of mitogen‐activated protein kinase
1994
Transformation of Mammalian Cells by Constitutively Active MAP Kinase Kinase
1994 StandoutScience
A role for casein kinase 2α in the Drosophila circadian clock
2002 StandoutNatureNobel
Protein Kinase A-mediated Phosphorylation of the β2-Adrenergic Receptor Regulates Its Coupling to Gs and Gi
2002 StandoutNobel
Protein kinases and phosphatases that act on histidine, lysine, or arginine residues in eukaryotic proteins: A possible regulator of the mitogen-activated protein kinase cascade
1995
Insulin disrupts β-adrenergic signalling to protein kinase A in adipocytes
2005 StandoutNatureNobel
Mitogen-activated Protein Kinase Kinase Inhibition Does Not Block the Stimulation of Glucose Utilization by Insulin
1995
The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation
1993
Induction of metaphase arrest in cleaving Xenopus embryos by MAP kinase
1993 Science
Biological Activity of Lenalidomide and Its Underlying Therapeutic Effects in Multiple Myeloma
2012
Increasing cAMP attenuates activation of mitogen-activated protein kinase.
1993
Bcr and Raf form a complex in vivo via 14-3-3 proteins.
1995
Binding of 14-3-3 Proteins to the Protein Kinase Raf and Effects on Its Activation
1994 Science
Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells.
1993 Standout
Small GTP-Binding Proteins
2001 Standout
The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated protein kinase pathway in L6 cells between Ras and Raf
1994
A Divergence in the MAP Kinase Regulatory Network Defined by MEK Kinase and Raf
1993 Science
Association of MEK1 with p21ras.GMPPNP is dependent on B-Raf.
1994
Regulation of Raf-1 kinase activity by the 14-3-3 family of proteins.
1995
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
Targeting Protein Phosphatase 1 (PP1) to the Actin Cytoskeleton: the Neurabin I/PP1 Complex Regulates Cell Morphology
2002
Sequence-Specific and Phosphorylation-Dependent Proline Isomerization: A Potential Mitotic Regulatory Mechanism
1997 Science
Ring-Strain-Enabled Reaction Discovery: New Heterocycles from Bicyclo[1.1.0]butanes
2015
Constitutive Activation of Toll-Mediated Antifungal Defense in Serpin-Deficient Drosophila
1999 StandoutScienceNobel
Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway
1995 StandoutNatureNobel
McsB Is a Protein Arginine Kinase That Phosphorylates and Inhibits the Heat-Shock Regulator CtsR
2009 StandoutScienceNobel
Raf-1 protein kinase activates the NF-kappa B transcription factor by dissociating the cytoplasmic NF-kappa B-I kappa B complex.
1993
β-Arrestin-Dependent Formation of β 2 Adrenergic Receptor-Src Protein Kinase Complexes
1999 StandoutScienceNobel
Stimulatory Effects of Yeast and Mammalian 14-3-3 Proteins on the Raf Protein Kinase
1994 Science
Function of Ras as a molecular switch in signal transduction.
1992
Signaling Through Scaffold, Anchoring, and Adaptor Proteins
1997 StandoutScience
Constitutive activation of Mek1 by mutation of serine phosphorylation sites.
1994
Myocyte Adrenoceptor Signaling Pathways
2003 StandoutScienceNobel
Human T-cell mitogen-activated protein kinase kinases are related to yeast signal transduction kinases.
1992
Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21ras.
1994 StandoutNobel
cAMP and beta gamma subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells.
1994
Mechanism of inhibition of Raf-1 by protein kinase A.
1994
Complexes between STE5 and components of the pheromone-responsive mitogen-activated protein kinase module.
1994
Differential Regulation of Raf-1 and B-Raf and Ras-Dependent Activation of Mitogen-Activated Protein Kinase by Cyclic AMP in PC12 Cells
1995
β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3
2000 StandoutScienceNobel
The c-mos proto-oncogene protein kinase turns on and maintains the activity of MAP kinase, but not MPF, in cell-free extracts of Xenopus oocytes and eggs.
1993 StandoutNobel
Cyclic AMP activates the mitogen-activated protein kinase cascade in PC12 cells.
1994
Raf-1 and p21v-ras cooperate in the activation of mitogen-activated protein kinase.
1993
The growth factor-inducible immediate-early gene 3CH134 encodes a protein-tyrosine-phosphatase.
1993
Structure, expression, and regulation of protein kinases involved in the phosphorylation of ribosomal protein S6.
1991
Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation.
1993
MAP kinase activator from insulin-stimulated skeletal muscle is a protein threonine/tyrosine kinase.
1992
MEK-1 phosphorylation by MEK kinase, Raf, and mitogen-activated protein kinase: analysis of phosphopeptides and regulation of activity.
1994
Enzymatic construction of highly strained carbocycles
2018 StandoutScienceNobel
Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase.
1993 Nobel
Cytoplasmic Signaling Pathways That Regulate Cardiac Hypertrophy
2001
Rapid stimulation of Ser/Thr protein kinases following treatment of Swiss 3T3 cells with bombesin. Involvement of casein kinase-2 in the signaling pathway of bombesin.
1992
A Dominant-Negative Mutant of mSOS1 Inhibits Insulin-Induced Ras Activation and Reveals Ras-Dependent and -Independent Insulin Signaling Pathways
1995
Binding of Neuroligins to PSD-95
1997 StandoutScienceNobel
Mos stimulates MAP kinase in Xenopus oocytes and activates a MAP kinase kinase in vitro.
1993
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
Norepinephrine Stimulates Apoptosis in Adult Rat Ventricular Myocytes by Activation of the β-Adrenergic Pathway
1998
Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum, and 12-O-tetradecanoylphorbol-13-acetate requires Raf and is necessary for transformation.
1994
Opposing Effects of β1- and β2-Adrenergic Receptors on Cardiac Myocyte Apoptosis
1999
Stimulation of mitogen-activated protein kinase by oncogenic Ras p21 in Xenopus oocytes. Requirement for Ras p21-GTPase-activating protein interaction.
1992
Multiple roles for protein phosphatase 1 in regulating the Xenopus early embryonic cell cycle.
1992
Purification of a murine protein-tyrosine/threonine kinase that phosphorylates and activates the Erk-1 gene product: relationship to the fission yeast byr1 gene product.
1992
CELLULAR FUNCTIONS REGULATED BY SRC FAMILY KINASES
1997 Standout
Overexpression of mitogen-activated protein kinase kinase (MAPKK) and its mutants in NIH 3T3 cells. Evidence that MAPKK involvement in cellular proliferation is regulated by phosphorylation of serine residues in its kinase subdomains VII and VIII.
1994 Nobel
NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses
1998 Standout
Synergistic activation by Ras and 14-3-3 protein of a mitogen-activated protein kinase kinase kinase named Ras-dependent extracellular signal-regulated kinase kinase stimulator.
1994
Mos Stimulates MAP Kinase in Xenopus Oocytes and Activates a MAP Kinase Kinase In Vitro
1993
G PROTEIN βγ SUBUNITS
1997
Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts
1993
Regulation of Raf-1-Dependent Signaling during Early Xenopus Development
1995
Repeated pulses of serotonin required for long-term facilitation activate mitogen-activated protein kinase in sensory neurons of Aplysia
1998 StandoutNobel
Phosphorylation of Xenopus mitogen-activated protein (MAP) kinase kinase by MAP kinase kinase kinase and MAP kinase.
1993
Identification of multiple extracellular signal-regulated kinases (ERKs) with antipeptide antibodies.
1991
B-Raf-dependent regulation of the MEK-1/mitogen-activated protein kinase pathway in PC12 cells and regulation by cyclic AMP.
1994
Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B
1993
Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds
2001 StandoutNobel
Signal transduction via the MAP kinases: proceed at your own RSK.
1993 Standout
Inactivation of glycogen synthase kinase-3β by phosphorylation: new kinase connections in insulin and growth-factor signalling
1993
Inhibition by cAMP of Ras-Dependent Activation of Raf
1993 Science
PTG, a Protein Phosphatase 1-Binding Protein with a Role in Glycogen Metabolism
1997 Science
Microtubule-associated protein 2 kinases, ERK1 and ERK2, undergo autophosphorylation on both tyrosine and threonine residues: implications for their mechanism of activation.
1991
Mos induces the in vitro activation of mitogen-activated protein kinases in lysates of frog oocytes and mammalian somatic cells.
1993
More on target with protein phosphorylation: conferring specificity by location.
1996
Identification of multifunctional ATP-citrate lyase kinase as the α-isoform of glycogen synthase kinase-3
1992
14-3-3 Is Not Essential for Raf-1 Function: Identification of Raf-1 Proteins That Are Biologically Activated in a 14-3-3- and Ras-Independent Manner
1995
Raf-1 protein kinase is important for progesterone-induced Xenopus oocyte maturation and acts downstream of mos.
1993
Similarities between somatic cells overexpressing the mos oncogene and oocytes during meiotic interphase.
1994 StandoutNobel
Ordered multisite protein phosphorylation. Analysis of glycogen synthase kinase 3 action using model peptide substrates.
1990
Reconstitution of the Raf-1-MEK-ERK signal transduction pathway in vitro.
1993
Lysophosphatidic acid stimulates mitogen-activated protein kinase activation via a G-protein-coupled pathway requiring p21ras and p74raf-1.
1993
Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation.
1996
Differential calcium dependence in the activation of c-Jun kinase and mitogen-activated protein kinase by muscarinic acetylcholine receptors in rat 1a cells
1995
Requirement for Raf and MAP kinase function during the meiotic maturation of Xenopus oocytes
1993
Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase
1994
The mitogen-activated protein kinase cascade is activated by B-Raf in response to nerve growth factor through interaction with p21ras.
1994
Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues.
1994
Function of PI3Kγ in Thymocyte Development, T Cell Activation, and Neutrophil Migration
2000 StandoutScienceNobel
Molecular Basis for Interactions of G Protein βγ Subunits with Effectors
1998 StandoutScienceNobel
Identification of the sites in MAP kinase kinase-1 phosphorylated by p74raf-1.
1994
Metabolism of ubiquitinated histones.
1981 StandoutNobel
The Double-Edged Sword of Autophagy Modulation in Cancer
2009
Complexes of Ras⋅GTP with Raf-1 and Mitogen-Activated Protein Kinase Kinase
1993 Science
Differential effects on cAMP on the MAP kinase cascade: evidence for a cAMP-insensitive step that can bypass Raf-1.
1995
Nuclear localization and regulation of erk- and rsk-encoded protein kinases.
1992
The mitogen-activated protein kinase signal transduction pathway
1993 Standout
Transduction of Receptor Signals by ß-Arrestins
2005 StandoutScienceNobel
Nuclear Localization and Regulation of erk-and rsk-Encoded Protein Kinases
1992
Works of Paul Dent being referenced
A myofibrillar protein phosphatase from rabbit skeletal muscle contains the β isoform of protein phosphatase‐1 complexed to a regulatory subunit which greatly enhances the dephosphorylation of myosin
1992
Ionizing radiation modulates vascular endothelial growth factor (VEGF) expression through multiple mitogen activated protein kinase dependent pathways
2001
Follicle-stimulating Hormone Activates Extracellular Signal-regulated Kinase but Not Extracellular Signal-regulated Kinase Kinase through a 100-kDa Phosphotyrosine Phosphatase
2003
Multisite phosphorylation of the glycogen‐binding subunit of protein phosphatase‐1G by cyclic AMP‐dependent protein kinase and glycogen synthase kinase‐3
1989
Targetting of protein phosphatase 1 to the sarcoplasmic reticulum of rabbit skeletal muscle by a protein that is very similar or identical to the G subunit that directs the enzyme to glycogen
1990
Inactivation of Raf-1 by a Protein-tyrosine Phosphatase Stimulated by GTP and Reconstituted by Gαi/o Subunits
1996
Ordered phosphorylation of p42mapk by MAP kinase kinase
1992
The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle
1990 Nature
Alteration of Ceramide Synthase 6/C16-Ceramide Induces Activating Transcription Factor 6-mediated Endoplasmic Reticulum (ER) Stress and Apoptosis via Perturbation of Cellular Ca2+ and ER/Golgi Membrane Network
2011
Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) Promotes Mitochondrial Dysfunction and Apoptosis Induced by 7-Hydroxystaurosporine and Mitogen-Activated Protein Kinase Kinase Inhibitors in Human Leukemia Cells That Ectopically Express Bcl-2 and Bcl-xL
2003
Bile acids as regulatory molecules
2009
Functional Mapping of the N-terminal Regulatory Domain in the Human Raf-1 Protein Kinase
1995
Identification of three in vivo phosphorylation sites on the glycogen‐binding subunit of protein phosphatase 1 from rabbit skeletal muscle, and their response to adrenaline
1990
Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation
2008
Reversal of Raf-1 Activation by Purified and Membrane-Associated Protein Phosphatases
1995 Science
Inhibition of the EGF-Activated MAP Kinase Signaling Pathway by Adenosine 3′,5′-Monophosphate
1993 Science
Mitogen-activated protein kinase kinase 1 (MKK1) is negatively regulated by threonine phosphorylation.
1994
Insulin activates a novel adipocyte mitogen-activated protein kinase kinase kinase that shows rapid phasic kinetics and is distinct from c-Raf.
1994
The Ras/Rac1/Cdc42/SEK/JNK/c-Jun Cascade Is a Key Pathway by Which Agonists Stimulate DNA Synthesis in Primary Cultures of Rat Hepatocytes
1998
Dual phosphorylation and autophosphorylation in mitogen-activated protein (MAP) kinase activation
1993
Identification and Characterization of a New Mammalian Mitogen-Activated Protein Kinase Kinase, MKK2
1993
The MPM-2 antibody inhibits mitogen-activated protein kinase activity by binding to an epitope containing phosphothreonine-183.
1994
Regulation of Raf-1 and Raf-1 Mutants by Ras-Dependent and Ras-Independent Mechanisms In Vitro
1995
Expression, purification and characterization of recombinant mitogen-activated protein kinase kinases
1994
Activation of Mitogen-Activated Protein Kinase Kinase by v-Raf in NIH 3T3 Cells and in Vitro
1992 StandoutScience
zeta PKC induces phosphorylation and inactivation of I kappa B-alpha in vitro.
1994
Bile Acid Regulation of C/EBPβ, CREB, and c-Jun Function, via the Extracellular Signal-Regulated Kinase and c-Jun NH2-Terminal Kinase Pathways, Modulates the Apoptotic Response of Hepatocytes
2003
Activation of the mitogen-activated protein kinase pathway in Triton X-100 disrupted NIH-3T3 cells by p21 ras and in vitro by plasma membranes from NIH 3T3 cells.
1993
Activation of Raf by ionizing radiation
1996 Nature
Ras-Induced Activation of Raf-1 Is Dependent on Tyrosine Phosphorylation
1996
Differential Regulation of the Mitogen-Activated Protein and Stress-Activated Protein Kinase Cascades by Adrenergic Agonists in Quiescent and Regenerating Adult Rat Hepatocytes
1997
Mutations in the Phosphatidylinositol-3-Kinase Pathway Predict for Antitumor Activity of the Inhibitor PX-866 whereas Oncogenic Ras Is a Dominant Predictor for Resistance
2008