Citation Impact
Citing Papers
The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP
2008 Standout
ATP-Binding Cassette Transporters and HDL Suppress Hematopoietic Stem Cell Proliferation
2010 Science
Gefitinib-Sensitizing EGFR Mutations in Lung Cancer Activate Anti-Apoptotic Pathways
2004 Science
α-Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
2010 StandoutScienceNobel
Similar Nucleotide Excision Repair Capacity in Melanocytes and Melanoma Cells
2010 StandoutNobel
Reciprocal Regulation of DUSP9 and DUSP16 Expression by HIF1 Controls ERK and p38 MAP Kinase Activity and Mediates Chemotherapy-Induced Breast Cancer Stem Cell Enrichment
2018 StandoutNobel
EglN2 associates with the NRF 1‐ PGC 1α complex and controls mitochondrial function in breast cancer
2015 StandoutNobel
Calcium-dependent Regulation of Protein Kinase D Revealed by a Genetically Encoded Kinase Activity Reporter
2006 StandoutNobel
Novel anticancer targets: revisiting ERBB2 and discovering ERBB3
2009
Treatment of kidney cancer
2009 StandoutNobel
Recommendations for Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Update
2013 Standout
EGFR associated expression profiles vary with breast tumor subtype
2007
Spatio-temporal Dynamics of Protein Kinase B/Akt Signaling Revealed by a Genetically Encoded Fluorescent Reporter
2004 StandoutNobel
The Concept of Synthetic Lethality in the Context of Anticancer Therapy
2005 StandoutNobel
K-ras Mutations and Benefit from Cetuximab in Advanced Colorectal Cancer
2008 Standout
mTOR Signaling in Growth Control and Disease
2012 Standout
pVHL Acts as an Adaptor to Promote the Inhibitory Phosphorylation of the NF-κB Agonist Card9 by CK2
2007 StandoutNobel
MYC on the Path to Cancer
2012 Standout
Genetic effects on gene expression across human tissues
2017 StandoutNature
EGFR Signal-Network Reconstruction Demonstrates Metabolic Crosstalk in EMT
2016
Quantitative single cell determination of ERK phosphorylation and regulation in relapsed and refractory primary acute myeloid leukemia
2005
Wound healing and its impairment in the diabetic foot
2005 Standout
Next-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategy
2011
Energy metabolism in tumor cells
2007
Multifunctional dendritic polymers in nanomedicine: opportunities and challenges
2011
Anaplastic lymphoma kinase proteins in growth control and cancer
2004
A pseudogene long-noncoding-RNA network regulates PTEN transcription and translation in human cells
2013
Clinical experience of MEK inhibitors in cancer therapy
2006
Differential effects of kinase cascade inhibitors on neoplastic and cytokine-mediated cell proliferation
2003
Macrophages in the Pathogenesis of Atherosclerosis
2011 Standout
Identification of the transforming EML4–ALK fusion gene in non-small-cell lung cancer
2007 StandoutNature
Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids
2010 Standout
Rasburicase: future directions in tumor lysis management
2008
p53-independent upregulation of miR-34a during oncogene-induced senescence represses MYC
2009
Introduction of Fluorine and Fluorine‐Containing Functional Groups
2013 Standout
Mutations in the RAS‐MAPK, PI(3)K (phosphatidylinositol‐3‐OH kinase) signaling network correlate with poor survival in a population‐based series of colon cancers
2008
Differential oestrogen receptor binding is associated with clinical outcome in breast cancer
2012 StandoutNature
The multilayered complexity of ceRNA crosstalk and competition
2014 StandoutNature
Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance
2006 Standout
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Using the Acropora digitifera genome to understand coral responses to environmental change
2011 StandoutNature
The epidermal growth factor receptor gene family as a target for therapeutic intervention in numerous cancers: what’s genetics got to do with it?
2005
JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis
2004
Upstream and downstream of mTOR
2004 Standout
Does the ribosome translate cancer?
2003
Regulation of cancer cell metabolism
2011 Standout
The complexity of PTEN: mutation, marker and potential target for therapeutic intervention
2004
Necrotizing Enterocolitis
2011 Standout
Universal sample preparation method for proteome analysis
2009 Standout
EGFR Mutation and Resistance of Non–Small-Cell Lung Cancer to Gefitinib
2005 Standout
Plant Polyphenols: Chemical Properties, Biological Activities, and Synthesis
2011 Standout
EMT: 2016
2016 Standout
The role of MAP kinases and MAP kinase phosphatase-1 in resistance to breast cancer treatment
2010
Macrophage Migration Inhibitory Factor Activates Hypoxia-Inducible Factor in a p53-Dependent Manner
2008 StandoutNobel
Rasburicase (Elitek): A Novel Agent for Tumor Lysis Syndrome
2005
The Structure of the MAPK Scaffold, MP1, Bound to Its Partner, p14
2004
What We Talk About When We Talk About Fat
2014 Standout
NADPH Oxidase and ERK Signaling Regulates Hyperoxia-induced Nrf2-ARE Transcriptional Response in Pulmonary Epithelial Cells
2004
AKT/PKB Signaling: Navigating the Network
2017 Standout
Rapid and transient activation of the ERK MAPK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on JAB1/CSN5 and Src kinase activity
2005
Global, In Vivo, and Site-Specific Phosphorylation Dynamics in Signaling Networks
2006 Standout
Pertuzumab plus Trastuzumab plus Docetaxel for Metastatic Breast Cancer
2011 Standout
Everolimus plus octreotide long-acting repeatable for the treatment of advanced neuroendocrine tumours associated with carcinoid syndrome (RADIANT-2): a randomised, placebo-controlled, phase 3 study
2011 Standout
The NS5A Protein of Hepatitis C Virus Is a Zinc Metalloprotein
2004 StandoutNobel
The Hepatitis C Virus NS5A Protein Activates a Phosphoinositide 3-Kinase-dependent Survival Signaling Cascade
2004
Doxorubicin Plus Sorafenib vs Doxorubicin Alone in Patients With Advanced Hepatocellular Carcinoma
2010
Targeting Wide-Range Oncogenic Transformation via PU24FCl, a Specific Inhibitor of Tumor Hsp90
2004 StandoutNobel
Resveratrol as an anticancer nutrient: molecular basis, open questions and promises
2005
Recommendations for the evaluation of risk and prophylaxis of tumour lysis syndrome (TLS) in adults and children with malignant diseases: an expert TLS panel consensus
2010
‘Genetic heterogeneity' in HER2/neu testing by fluorescence in situ hybridization: a study of 2522 cases
2012
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
2014 Standout
Caspase‐dependent cleavage of 170‐kDa P‐glycoprotein during apoptosis of human T‐lymphoblastoid CEM cells
2006
Polyunsaturated fatty acids block platelet-activating factor-induced phosphatidylinositol 3 kinase/Akt-mediated apoptosis in intestinal epithelial cells
2008
Malignant melanoma: genetics and therapeutics in the genomic era
2006
Reactions of trimethylsilyl fluorosulfonyldifluoroacetate with purine and pyrimidine nucleosides
2008
Time-resolved Mass Spectrometry of Tyrosine Phosphorylation Sites in the Epidermal Growth Factor Receptor Signaling Network Reveals Dynamic Modules
2005
Gene expression profiling reveals the profound upregulation of hypoxia-responsive genes in primary human astrocytes
2006
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Phosphatidylinositol 3′-Kinase Activation Leads to Multidrug Resistance Protein-1 Expression and Subsequent Chemoresistance in Advanced Prostate Cancer Cells
2004
γ‐Synuclein and the progression of cancer
2007
Targeting the mTOR Signaling Network for Cancer Therapy
2009
The Tumor Lysis Syndrome
2011 Standout
Persistent ERK/MAPK Activation Promotes Lactotrope Differentiation and Diminishes Tumorigenic Phenotype
2014
Guidelines for the Management of Pediatric and Adult Tumor Lysis Syndrome: An Evidence-Based Review
2008 Standout
Simultaneous activation of multiple signal transduction pathways confers poor prognosis in acute myelogenous leukemia
2006
Apoptosis and autophagy as mechanisms of dinoflagellate symbiont release during cnidarian bleaching: every which way you lose
2007
Fluorescent Sensors for Measuring Metal Ions in Living Systems
2014 Standout
Mechanism of von Hippel-Lindau Protein-Mediated Suppression of Nuclear Factor kappa B Activity
2005
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma
2018 Standout
Molecular targets of dietary agents for prevention and therapy of cancer
2006 Standout
Grafted human-induced pluripotent stem-cell–derived neurospheres promote motor functional recovery after spinal cord injury in mice
2011 StandoutNobel
microRNAs regulate adipocyte differentiation
2013
Fibrinogen as a key regulator of inflammation in disease
2011
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Works of Patrick M. Navolanic being referenced
Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors
2008
Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance
2006
Elitek™–rasburicase: an effective means to prevent and treat hyperuricemia associated with tumor lysis syndrome, a Meeting Report, Dallas, Texas, January 2002
2003
Analysis of G(-174)C IL-6 polymorphism and plasma concentrations of inflammatory markers in patients with type 2 diabetes and peripheral arterial disease
2006
Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy
2003
Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention
2003
Analysis of BRAF Mutation in Primary and Metastatic Melanoma
2005
Requirement for the PI3K/Akt pathway in MEK1-mediated growth and prevention of apoptosis: identification of an Achilles heel in leukemia
2003
Role of the Raf signal transduction cascade in the in vitro resistance to the anticancer drug doxorubicin.
2001
Pharmacological breast cancer therapy (Review)
2005
Raf-1 and Bcl-2 induce distinct and common pathways that contribute to breast cancer drug resistance.
2003
Regulation of cell cycle progression and apoptosis by the Ras/Raf/MEK/ERK pathway (Review).
2003
EGFR family signaling and its association with breast cancer development and resistance to chemotherapy (Review)
2003
Docetaxel Cytotoxicity is Enhanced by Inhibition of the Raf/MEK/ERK Signal Transduction Pathway
2003
Plasma levels and zymographic activities of matrix metalloproteinases 2 and 9 in type II diabetics with peripheral arterial disease
2005