Citation Impact
Citing Papers
Evidence that Resistance to Nilotinib May Be Due to BCR-ABL, Pgp, or Src Kinase Overexpression
2008
Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides
2019 StandoutNobel
PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity
2017 StandoutNature
1-(2-Carboxyindol-5-yloxy)propan-2-ones as inhibitors of human cytosolic phospholipase A2α: Synthesis, biological activity, metabolic stability, and solubility
2008
IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer
2004 Standout
An inhibitor of I?B kinase, BMS-345541, blocks endothelial cell adhesion molecule expression and reduces the severity of dextran sulfate sodium-induced colitis in mice
2003
NF-κB signaling in inflammation
2017 Standout
pVHL Acts as an Adaptor to Promote the Inhibitory Phosphorylation of the NF-κB Agonist Card9 by CK2
2007 StandoutNobel
Necroptosis and its role in inflammation
2015 StandoutNature
Nuclear factor-κB inhibitors as sensitizers to anticancer drugs
2005
Human cholesterol 7α-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype
2002
Inducible but Not Constitutive Expression of PD-L1 in Human Melanoma Cells Is Dependent on Activation of NF-κB
2015
Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis
2014 Nature
Rel/NF‐κB family member RelA regulates NK1.1− to NK1.1+ transition as well as IL‐15‐induced expansion of NKT cells
2008
Cancer drug resistance: an evolving paradigm
2013 Standout
A cytokine-mediated link between innate immunity, inflammation, and cancer
2007 Standout
Activation and regulation of the inflammasomes
2013 Standout
NF-κB, the first quarter-century: remarkable progress and outstanding questions
2012 Standout
DAI/ZBP1/DLM-1 Complexes with RIP3 to Mediate Virus-Induced Programmed Necrosis that Is Targeted by Murine Cytomegalovirus vIRA
2012
Inflammation and Cancer: When NF-κB Amalgamates the Perilous Partnership
2005
The IKK NF-κB system: a treasure trove for drug development
2004
Fluorine in Medicinal Chemistry
2015
Allosteric inhibitors of Bcr-abl–dependent cell proliferation
2006
Chemical probing reveals insights into the signaling mechanism of inflammasome activation
2010
Intracellular Toll-like Receptors
2010 StandoutNobel
Targeting the NF-κB signaling pathway in Notch1-induced T-cell leukemia
2006
Glycans in cancer and inflammation — potential for therapeutics and diagnostics
2005 StandoutNobel
Nuclear factor-κB in cancer development and progression
2006 StandoutNature
Targeting cancer with small molecule kinase inhibitors
2008 Standout
IKK/NF- B signaling: balancing life and death - a new approach to cancer therapy
2005 Standout
Catalytic Functionalization of Indoles in a New Dimension
2009 Standout
The JAK/STAT signaling pathway: from bench to clinic
2021 Standout
Regulation and Function of the PD-L1 Checkpoint
2018 Standout
Can NF-κB be a target for novel and efficient anti-cancer agents?
2006
Inflammatory caspases are innate immune receptors for intracellular LPS
2014 StandoutNature
Signalling, inflammation and arthritis: NF- B and its relevance to arthritis and inflammation
2008
IKK mediates ischemia-induced neuronal death
2005
Molecular mechanisms of necroptosis: an ordered cellular explosion
2010 Standout
Systemic and Intrathecal Effects of a Novel Series of Phospholipase A2 Inhibitors on Hyperalgesia and Spinal Prostaglandin E2 Release
2005
A highly selective inhibitor of IκB kinase, BMS‐345541, blocks both joint inflammation and destruction in collagen‐induced arthritis in mice
2003
Crosstalk in NF-κB signaling pathways
2011 Standout
Signaling to NF-κB
2004 Standout
Comprehensive analysis of kinase inhibitor selectivity
2011 Standout
The advent and development of organocatalysis
2008 StandoutNature
Biaryl Phosphane Ligands in Palladium‐Catalyzed Amination
2008 Standout
Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens
2015 StandoutNobel
A General Strategy for Creating “Inactive-Conformation” Abl Inhibitors
2006
IFN-γ-induced upregulation of Fcγ-receptor-I during activation of monocytic cells requires the PKR and NFκB pathways
2006
Benzhydrylquinazolinediones: Novel cytosolic phospholipase A2α inhibitors with improved physicochemical properties
2009
Anti-TNF-α therapies: the next generation
2003
The HepaRG cell line: a uniquein vitrotool for understanding drug metabolism and toxicology in human
2012
A selective novel low‐molecular‐weight inhibitor of IκB kinase‐β (IKK‐β) prevents pulmonary inflammation and shows broad anti‐inflammatory activity
2005
Interspecies scaling and prediction of human clearance: comparison of small- and macro-molecule drugs
2011
Integrating cell-signalling pathways with NF-κB and IKK function
2006 Standout
Immunogenic cell death and DAMPs in cancer therapy
2012 Standout
Interferon-inducible antiviral effectors
2008 Standout
NF-κB: linking inflammation and immunity to cancer development and progression
2005 Standout
Divergent Synthesis of Cyclopropane‐Containing Lead‐Like Compounds, Fragments and Building Blocks through a Cobalt Catalyzed Cyclopropanation of Phenyl Vinyl Sulfide
2017
Trends in Kinase Selectivity: Insights for Target Class-Focused Library Screening
2010
NF-κB Regulates PD-1 Expression in Macrophages
2015
3d Transition Metals for C–H Activation
2018 Standout
Enantioselective Palladium(II)‐Catalyzed Oxidative Aminofluorination of Unactivated Alkenes with Et4NF⋅3 HF as a Fluoride Source
2019
A mutation of Ikbkg causes immune deficiency without impairing degradation of IκBα
2010 StandoutNobel
RBPjκ-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development
2010 StandoutNobel
Enantioselective Palladium(II)‐Catalyzed Oxidative Aminofluorination of Unactivated Alkenes with Et4NF⋅3 HF as a Fluoride Source
2019
Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals
2014 Standout
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
2011 StandoutNobel
Design, Synthesis, and Biological Evaluation of 3-(1-Aryl-1H-indol-5-yl)propanoic Acids as New Indole-Based Cytosolic Phospholipase A2α Inhibitors
2014
Immunometabolism governs dendritic cell and macrophage function
2015 Standout
Regulation and Function of NF-κB Transcription Factors in the Immune System
2009 Standout
Cartilage-specific RBPjκ-dependent and -independent Notch signals regulate cartilage and bone development
2012 StandoutNobel
The Enzymes, Regulation, and Genetics of Bile Acid Synthesis
2003 Standout
Comprehensive Review in Current Developments of Imidazole-Based Medicinal Chemistry
2013
TLR7 stimulation in human plasmacytoid dendritic cells leads to the induction of early IFN-inducible genes in the absence of type I IFN
2009
Pore-forming activity and structural autoinhibition of the gasdermin family
2016 StandoutNature
Homologation of the Fischer Indolization: A Quinoline Synthesis via Homo‐Diaza‐Cope Rearrangement
2020 StandoutNobel
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1
2011 StandoutNobel
Stereoselective Enzymatic Synthesis of Heteroatom-Substituted Cyclopropanes
2018 StandoutNobel
Oxysterols: Modulators of Cholesterol Metabolism and Other Processes
2000
Precise Modulation of CO2 Sorption in Ti8Ce2–Oxo Clusters: Elucidating Lewis Acidity of the Ce Metal Sites and Structural Flexibility
2024 StandoutNobel
Synthesis of Polyfluoro Ketones for Selective Inhibition of Human Phospholipase A2Enzymes
2008
Lipopolysaccharide Activation of the TPL-2/MEK/Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase Cascade Is Regulated by IκB Kinase-Induced Proteolysis of NF-κB1 p105
2004
Single-nanometer iron oxide nanoparticles as tissue-permeable MRI contrast agents
2021 StandoutNobel
Human cholesterol 7α-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype
2002
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Inhibition of Cytosolic Phospholipase A2α: Hit to Lead Optimization
2005
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
Applications of Fluorine in Medicinal Chemistry
2015 Standout
Enantioselective Synthesis of a Highly Potent Selective Serotonin Reuptake Inhibitor. An Application of Imidazolidinone Catalysis to the Alkylation of Indoles with an α,β-Disubstituted α,β-Unsaturated Aldehyde
2005
Works of Patrick Brassil being referenced
Discovery of novel hedgehog antagonists from cell-based screening: Isosteric modification of p38 bisamides as potent inhibitors of SMO
2012
Neurochemical, pharmacokinetic, and behavioral effects of the novel selective serotonin reuptake inhibitor BMS-505130
2005
Novel N-Linked Aminopiperidine Inhibitors of Bacterial Topoisomerase Type II with Reduced pKa: Antibacterial Agents with an Improved Safety Profile
2012
Expression and distribution of cholesterol 7α-hydroxylase in rat liver
1995
Evaluation of Multiple in Vitro Systems for Assessment of CYP3A4 Induction in Drug Discovery: Human Hepatocytes, Pregnane X Receptor Reporter Gene, and Fa2N-4 and HepaRG Cells
2009
Estimation of Human Drug Clearance Using Multiexponential Techniques
2008
Synthesis and structure–activity relationship of imidazo(1,2-a)thieno(3,2-e)pyrazines as IKK-β inhibitors
2007
BMS-345541 Is a Highly Selective Inhibitor of IκB Kinase That Binds at an Allosteric Site of the Enzyme and Blocks NF-κB-dependent Transcription in Mice
2003
BMS-229724 Is a Tight-Binding Inhibitor of Cytosolic Phospholipase A2 That Acts at the Lipid/Water Interface and Possesses Anti-Inflammatory Activity in Skin Inflammation Models
2001
Novel N-Linked Aminopiperidine Inhibitors of Bacterial Topoisomerase Type II: Broad-Spectrum Antibacterial Agents with Reduced hERG Activity
2011
Development of Gut-Selective Pan-Janus Kinase Inhibitor TD-1473 for Ulcerative Colitis: A Translational Medicine Programme
2020