Citation Impact
Citing Papers
Role of Mitochondrial RNA Polymerase in the Toxicity of Nucleotide Inhibitors of Hepatitis C Virus
2015
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
Cationic steroid antibiotics demonstrate DNA delivery properties
2005
Direct and Catalytic C ‐Glycosylation of Arenes: Expeditious Synthesis of the Remdesivir Nucleoside**
2021 StandoutNobel
Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides
2019 StandoutNobel
Therapeutic siRNA: state of the art
2020
Identification of a Small Interface between the Methyltransferase and RNA Polymerase of NS5 that is Essential for Zika Virus Replication
2018 StandoutNobel
Lipid nanoparticle technology for therapeutic gene regulation in the liver
2020
Crystal Structure of the Full-Length Japanese Encephalitis Virus NS5 Reveals a Conserved Methyltransferase-Polymerase Interface
2013
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
The structural model of Zika virus RNA-dependent RNA polymerase in complex with RNA for rational design of novel nucleotide inhibitors
2018
Mitochondrial iPLA2 Activity Modulates the Release of Cytochrome c from Mitochondria and Influences the Permeability Transition
2006
Structure and function of the Zika virus full-length NS5 protein
2017
Dynamic Covalent Chemistry
2002 StandoutNobel
Lipopeptide detergents designed for the structural study of membrane proteins
2003
Inhibition of Macrophage Ca2+-independent Phospholipase A2 by Bromoenol Lactone and Trifluoromethyl Ketones
1995
Synthetic Inhibitors of Elastase
1994
Sensitivity of Mitochondrial Transcription and Resistance of RNA Polymerase II Dependent Nuclear Transcription to Antiviral Ribonucleosides
2012
Unconventional miR-122 binding stabilizes the HCV genome by forming a trimolecular RNA structure
2013 StandoutNobel
Glycosylation in Cellular Mechanisms of Health and Disease
2006 Standout
New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays
2010 Standout
Purification of Zika virus RNA-dependent RNA polymerase and its use to identify small-molecule Zika inhibitors
2016
Chemical and enzymatic synthesis of glycopolymers
2000
Nucleotide Polymerase Inhibitor Sofosbuvir plus Ribavirin for Hepatitis C
2013
Fluorine in Medicinal Chemistry
2015
Lessons Learnt from Assembling Screening Libraries for Drug Discovery for Neglected Diseases
2007
Substrate selectivity of Dengue and Zika virus NS5 polymerase towards 2′-modified nucleotide analogues
2016
Synthesis of carbamate-linked lipids for gene delivery
2005
Hepatitis C Virus Proteins: From Structure to Function
2013
2-(dimethylamino)ethyl methacrylate based (co)polymers as gene transfer agents
1998
Identification of Calcium-independent Phospholipase A2 (iPLA2) β, and Not iPLA2γ, as the Mediator of Arginine Vasopressin-induced Arachidonic Acid Release in A-10 Smooth Muscle Cells
2002
Saccharide Display on Microtiter Plates
2002
Pharmacological investigation of the role of leukotrienes in the pathogenesis of experimental NSAID gastropathy
1992
Mediators of Chronic Obstructive Pulmonary Disease
2004
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Sofosbuvir Inhibits Hepatitis E Virus Replication In Vitro and Results in an Additive Effect When Combined With Ribavirin
2015 StandoutNobel
Stereospecific synthesis of β-d-allopyranosides by dihydroxylation of β-d-erythro-2,3-dideoxyhex-2-enopyranosides
2001
Combination Therapy of an Inhibitor of Group VIA Phospholipase A2 with Paclitaxel Is Highly Effective in Blocking Ovarian Cancer Development
2011
Group VIA Ca2+-independent phospholipase A2 (iPLA2β) and its role in β-cell programmed cell death
2010
Gastrointestinal Toxicity of Nonsteroidal Antiinflammatory Drugs
1999 Standout
Hepatitis C Virus-Specific Directly Acting Antiviral Drugs
2013
Lipid nanoparticles for nucleic acid delivery: Current perspectives
2020
The ChEMBL database in 2017
2016 Standout
Studies toward the oxidative and reductive activation of C–S bonds in 2′-S-aryl-2ʹ-thiouridine derivatives
2016
Comparative transfection studies of human ovarian carcinoma cellsin vitro,ex vivo andin vivo with poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes
1999
Crystal Structure of the Hepatitis C Virus NS3 Protease Domain Complexed with a Synthetic NS4A Cofactor Peptide
1996 StandoutNobel
Nature of linkage between the cationic headgroup and cholesteryl skeleton controls gene transfection efficiency
2000
A computational approach for predicting off-target toxicity of antiviral ribonucleoside analogues to mitochondrial RNA polymerase
2018 StandoutNobel
Role of Calcium-independent Phospholipase A2β in High Glucose-induced Activation of RhoA, Rho Kinase, and CPI-17 in Cultured Vascular Smooth Muscle Cells and Vascular Smooth Muscle Hypercontractility in Diabetic Animals
2010
Synthesis and Microcontact Printing of Dual End‐Functionalized Mucin‐like Glycopolymers for Microarray Applications
2009 StandoutNobel
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
Insulin Secretory Responses and Phospholipid Composition of Pancreatic Islets from Mice That Do Not Express Group VIA Phospholipase A2 and Effects of Metabolic Stress on Glucose Homeostasis
2006
Flavivirus RNA transactions from viral entry to genome replication
2016
Seven-transmembrane receptors
2002 StandoutNobel
The regiochemical distribution of positive charges along cholesterol polyamine carbamates plays significant roles in modulating DNA binding affinity and lipofection
1999
Combinatorial synthesis of carbohydrates
1999
Calcium-independent phospholipase A2 and apoptosis
2006
TMEM41B Is a Pan-flavivirus Host Factor
2020 StandoutNobel
Adenosine triphosphate analogs can efficiently inhibit the Zika virus RNA-dependent RNA polymerase
2016
Gene transfection activities of amphiphilic steroid–polyamine conjugates
2000
Stem cell-derived polarized hepatocytes
2020 StandoutNobel
Bromoenol Lactone Inhibits Magnesium-dependent Phosphatidate Phosphohydrolase and Blocks Triacylglycerol Biosynthesis in Mouse P388D1 Macrophages
1996
The Unexpected Importance of the Primary Structure of the Hydrophobic Part of One-Component Ionizable Amphiphilic Janus Dendrimers in Targeted mRNA Delivery Activity
2022 StandoutNobel
Inhibitors of the Tick-Borne, Hemorrhagic Fever-Associated Flaviviruses
2014
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy
2023 StandoutNobel
Palladium-mediated intramolecular cyclization of substituted pentynoic acids. A new route to γ-arylidenebutyrolactones
1996
Reduction-Sensitive Lipopolyamines as a Novel Nonviral Gene Delivery System for Modulated Release of DNA with Improved Transgene Expression
2000
Methodologies for Generating Solution-Phase Combinatorial Libraries
2000
Synthesis of Heterocycles via Electrophilic Cyclization of Alkynes Containing Heteroatom
2011 Standout
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Activated Ketones as Inhibitors of Intracellular Ca2+-Dependent and Ca2+-Independent Phospholipase A2
1996
A Second Leukotriene B4 Receptor, Blt2
2000
Evidence for a stepwise mechanism in formal hetero-Diels-Alder reactions of N-arylimines
1996
Chemical Glycobiology
2001 StandoutScienceNobel
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
2021 StandoutNobel
Ultrastructural analysis of hepatitis C virus particles
2013 StandoutNobel
The ProTide Prodrug Technology: From the Concept to the Clinic
2017
New procedures for the selective synthesis of 2(2H)-pyranone derivatives and 3-aryl-4-iodoisocoumarins
2002
Nonviral Vectors for Gene Delivery
2008 Standout
Redox-active nuisance screening compounds and their classification
2011
A Bromoenol Lactone Suicide Substrate Inactivates Group VIA Phospholipase A2 by Generating a Diffiusible Bromomethyl Keto Acid That Alkylates Cysteine Thiols
2005
Recent developments in polymer supported syntheses of oligosaccharides and glycopeptides
1999
Effects of Biological Oxidants on the Catalytic Activity and Structure of Group VIA Phospholipase A2
2006
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
The bacterial cell wall as a source of antibacterial targets
2002
Bile Acid−Oligopeptide Conjugates Interact with DNA and Facilitate Transfection
2006
Suicide inhibition of canine myocardial cytosolic calcium-independent phospholipase A2. Mechanism-based discrimination between calcium-dependent and -independent phospholipases A2.
1991
Electrophilic Cyclization of 2-Chalcogenealkynylanisoles: Versatile Access to 2-Chalcogen-benzo[b]furans
2009
Precise Modulation of CO2 Sorption in Ti8Ce2–Oxo Clusters: Elucidating Lewis Acidity of the Ce Metal Sites and Structural Flexibility
2024 StandoutNobel
Recent developments in oligosaccharide synthesis
2000
Copper-Catalyzed Synthesis of Mixed Alkyl Aryl Phosphonates
2014 StandoutNobel
Homogeneous Catalysis in Supercritical Fluids
1999 StandoutNobel
Tandem Facial Amphiphiles for Membrane Protein Stabilization
2010 StandoutNobel
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2001 StandoutScience
Site-Selective Functionalization of Hydroxyl Groups in Carbohydrate Derivatives
2018
Rational Tuning of Fluorobenzene Probes for Cysteine‐Selective Protein Modification
2018 StandoutNobel
Synthetic Organic Electrochemical Methods Since 2000: On the Verge of a Renaissance
2017 Standout
Structure−Activity Relationships of Water-Soluble Cationic Methacrylate/Methacrylamide Polymers for Nonviral Gene Delivery
1999
Selective synthesis of natural and unnatural 5,6-disubstituted 2(2H)-pyranones via iodolactonization of 5-substituted (Z)-2-en-4-ynoic acids
2001
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Target-Oriented and Diversity-Oriented Organic Synthesis in Drug Discovery
2000 StandoutScience
Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19
2020
Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers
2021 StandoutNobel
Der Stand der Totalsynthese zu Beginn des 21. Jahrhunderts
2000
In vivo hematopoietic stem cell modification by mRNA delivery
2023 StandoutScienceNobel
Highly efficient full-length hepatitis C virus genotype 1 (strain TN) infectious culture system
2012
Solid-Phase Oligosaccharide Synthesis and Combinatorial Carbohydrate Libraries
2000
De Novo Asymmetric Bio- and Chemocatalytic Synthesis of Saccharides − Stereoselective Formal O-Glycoside Bond Formation Using Palladium Catalysis
2003 StandoutNobel
Transition-Metal-Catalyzed Addition of Heteroatom−Hydrogen Bonds to Alkynes
2004 Standout
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
2022 StandoutNobel
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
Carbohydrate Chips for Studying High-Throughput Carbohydrate−Protein Interactions
2004
Analysis of Ribonucleotide 5′-Triphosphate Analogs as Potential Inhibitors of Zika Virus RNA-Dependent RNA Polymerase by Using Nonradioactive Polymerase Assays
2016
Comprehensive Survey of Combinatorial Library Synthesis: 1998
1999
Chemistry: Chemical con artists foil drug discovery
2014 StandoutNature
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Probing Glycosyltransferase Activities with the Staudinger Ligation
2003 StandoutNobel
Design and synthesis of fluconazole/bile acid conjugate using click reaction
2006
Novel Therapies for Hepatitis C: Insights from the Structure of the Virus
2011
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
A Novel Catalyst with a Cuboidal PdMo3S4 Core for the Cyclization of Alkynoic Acids to Enol Lactones
1996
Regio- and stereoselective synthesis of γ-alkylidenebutenolides and related compounds
1997 StandoutNobel
Molecular docking revealed the binding of nucleotide/side inhibitors to Zika viral polymerase solved structures
2018
Barrier-Independent, Fitness-Associated Differences in Sofosbuvir Efficacy against Hepatitis C Virus
2016 StandoutNobel
A Simple Procedure for Connecting Two Carbohydrate Moieties by Click Chemistry Techniques
2007
Works of Michael J. Sofia being referenced
Structural basis for RNA replication by the hepatitis C virus polymerase
2015 Science
Pharmacologic actions of the second generation leukotriene B 4 receptor antagonist LY293111: in vivo pulmonary studies
2000
Mechanism of Activation of PSI-7851 and Its Diastereoisomer PSI-7977
2010
Effects of two leukotriene B4 (LTB4) receptor antagonists (LY255283 and SC-41930) on LTB4-induced human neutrophil adhesion and superoxide production
1991
Synthesis and biological evaluation of analogues of bacterial lipid I
2000
Inhibition of hepatitis C virus NS5A by fluoro-olefin based γ-turn mimetics
2012
Carbohydrate-based combinatorial libraries
1997
Activity and the metabolic activation pathway of the potent and selective hepatitis C virus pronucleotide inhibitor PSI-353661
2011
Synthesis and anti-HCV activity of 3′,4′-oxetane nucleosides
2010
Pharmacologic Actions of the Second-Generation Leukotriene B4 Receptor Antagonist LY293111: In Vitro Studies
1999
Nucleoside, Nucleotide, and Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B RNA-Dependent RNA-Polymerase
2011
Analysis of the interaction of haloenol lactone suicide substrates with .alpha.-chymotrypsin using computer graphics and molecular mechanics
1985
ARB-1740, a RNA Interference Therapeutic for Chronic Hepatitis B Infection
2018
Carbohydrate-Based Small-Molecule Scaffolds for the Construction of Universal Pharmacophore Mapping Libraries
1998
Antibacterial activity of synthetic analogues based on the disaccharide structure of moenomycin, an inhibitor of bacterial transglycosylase
2000
Durable inhibition of hepatitis B virus replication and antigenemia using a subcutaneously administered siRNA agent in preclinical models
2018
An Efficient and Diastereoselective Synthesis of PSI-6130: A Clinically Efficacious Inhibitor of HCV NS5B Polymerase
2009
FRI-184-Function and drug combination studies in cell culture models for AB-729, a subcutaneously administered siRNA investigational agent for chronic hepatitis B infection
2019
Hepatitis B Virus Therapeutic Agent ARB-1740 Has Inhibitory Effect on Hepatitis Delta Virus in a New Dually-Infected Humanized Mouse Model
2018
Inhibition of Hepatitis C Virus Replicon RNA Synthesis by PSI-352938, a Cyclic Phosphate Prodrug of β-d -2′-Deoxy-2′-α-Fluoro-2′-β-C-Methylguanosine
2011
Stereospecific Solution- and Solid-Phase Glycosylations. Synthesis of β-Linked Saccharides and Construction of Disaccharide Libraries Using Phenylsulfenyl 2-Deoxy-2-Trifluoroacetamido Glycopyranosides as Glycosyl Donors1
1999
Cationic facial amphiphiles: a promising class of transfection agents.
1996
Synthesis of Diastereomerically Pure Nucleotide Phosphoramidates
2011
Structure of Hepatitis C Virus Polymerase in Complex with Primer-Template RNA
2012
PSI-7851, a Pronucleotide of β- d -2′-Deoxy-2′-Fluoro-2′- C -Methyluridine Monophosphate, Is a Potent and Pan-Genotype Inhibitor of Hepatitis C Virus Replication
2010
The efficient synthesis of a bis-glycosylated steroid drug transport reagent: Methyl 3-β-amino-7α, 12α-di(1′α-glucosyl)-5β-cholate (TC002)
1997
Synthesis of five-membered halo enol lactone analogs of .alpha.-amino acids: potential protease suicide substrates
1983
Haloenol lactones. Potent enzyme-activated irreversible inhibitors for alpha-chymotrypsin.
1983
Simple and Efficient Method for the Oxidation of Sulfides to Sulfoxides: Application to the Preparation of Glycosyl Sulfoxides
1996
Solid phase synthesis of peptidoglycan monomers for the generation of a combinatorial library
1996
3-(Acylamido)-4-phenyl-6(E)-(iodomethylene)tetrahydro-2-pyranones. Synthesis of novel amino acid analogs
1985
Discovery of a β-d -2′-Deoxy-2′-α-fluoro-2′-β-C-methyluridine Nucleotide Prodrug (PSI-7977) for the Treatment of Hepatitis C Virus
2010
An Empirical Process for the Design of High-Throughput Screening Deck Filters
2006
Chemistry and cellular aspects of cationic facial amphiphiles
1998
Enol lactone inhibitors of serine proteases. The effect of regiochemistry on the inactivation behavior of phenyl-substituted (halomethylene)tetra- and dihydrofuranones and tetrahydropyranones toward .alpha.-chymotrypsin: stable acyl enzyme intermediate
1986
Stereospecific reductive methylation via a radical cyclization desilylation process
1986