Standout Papers

Participation of p53 protein in the cellular response to DNA damage. 1991 2026 2002 2014 3.3k
  1. Participation of p53 protein in the cellular response to DNA damage. (1991)
    Michael B. Kastan, Onyinye Onyekwere et al. PubMed
  2. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation (2003)
    Christopher J. Bakkenist, Michael B. Kastan Nature
  3. Cell Cycle Control and Cancer (1994)
    Leland H. Hartwell, Michael B. Kastan Science
  4. Cell-cycle checkpoints and cancer (2004)
    Michael B. Kastan, Jiří Bártek Nature
  5. Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53 (1998)
    Christine E. Canman, Dae‐Sik Lim et al. Science
  6. Wild-type p53 is a cell cycle checkpoint determinant following irradiation. (1992)
    Steven J. Kuerbitz, Beverly Plunkett et al. Proceedings of the National Academy of Sciences
  7. The complexity of p53 modulation: emerging patterns from divergent signals (1998)
    Amato J. Giaccia, Michael B. Kastan Genes & Development
  8. Conversion of Bcl-2 to a Bax-like Death Effector by Caspases (1997)
    Emily H. Cheng, David G. Kirsch et al. Science
  9. The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis (2010)
    Hasan Zaki, Kelli L. Boyd et al. Immunity
  10. Interaction of the p53-Regulated Protein Gadd45 with Proliferating Cell Nuclear Antigen (1994)
    Qimin Zhan, Insoo Bae et al. Science
  11. DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways. (1994)
    William G. Nelson, Michael B. Kastan Molecular and Cellular Biology
  12. DNA damage induces phosphorylation of the amino terminus of p53 (1997)
    Janet D. Siliciano, Christine E. Canman et al. Genes & Development
  13. Substrate Specificities and Identification of Putative Substrates of ATM Kinase Family Members (1999)
    Seong‐Tae Kim, Dae‐Sik Lim et al. Journal of Biological Chemistry
  14. ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway (2000)
    Dae‐Sik Lim, Seong‐Tae Kim et al. Nature
  15. The many substrates and functions of ATM (2000)
    Michael B. Kastan, Dae‐Sik Lim Nature Reviews Molecular Cell Biology
  16. ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS (2010)
    Angela Alexander, Jinhee Kim et al. Proceedings of the National Academy of Sciences
  17. Regulation of p53 Translation and Induction after DNA Damage by Ribosomal Protein L26 and Nucleolin (2005)
    Masatoshi Takagi, Michael J. Absalon et al. Cell
  18. ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage (2001)
    Ruth Maya, Moshe Balass et al. Genes & Development
  19. Autophagy Links Inflammasomes to Atherosclerotic Progression (2012)
    Babak Razani, Feng Chu et al. Cell Metabolism
  20. The DNA Damage Response: Implications for Tumor Responses to Radiation and Chemotherapy (2014)
    Michael Goldstein, Michael B. Kastan Annual Review of Medicine

Immediate Impact

35 by Nobel laureates 186 from Science/Nature 440 standout
Sub-graph 1 of 12

Citing Papers

NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux
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134 intermediate papers

Works of Michael B. Kastan being referenced

Multiple roles of ATM in monitoring and maintaining DNA integrity
2010
Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage.
1993
and 31 more

Author Peers

Author Last Decade Papers Cites
Michael B. Kastan 30153 18219 8218 153 38.5k
Carol Prives 25364 20763 6107 216 33.3k
Karen H. Vousden 34167 24148 12175 239 48.4k
Albert J. Fornace 25494 12815 7682 409 35.4k
Yue Xiong 23999 11215 5305 253 33.7k
Moshe Oren 34533 28528 9746 323 48.3k
Jiří Lukáš 30184 17547 5673 206 36.7k
Geoffrey M. Wahl 21519 10995 4683 176 29.7k
David A. Tuveson 19285 20810 9180 200 40.1k
Kornélia Polyák 29875 26258 14562 198 48.9k
Wafik S. El‐Deiry 32596 23024 9235 569 46.2k

All Works

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