Citation Impact
Citing Papers
An enumerative algorithm for de novo design of proteins with diverse pocket structures
2020 StandoutNobel
Recent applications of protein crystallography and structure-guided drug design
2005
Fragment-based lead discovery
2004
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
A two stage click-based library of protein tyrosine phosphatase inhibitors
2006
Anatomical and physiological evidence for D1 and D2 dopamine receptor colocalization in neostriatal neurons
2000 StandoutNobel
Modular click chemistry libraries for functional screens using a diazotizing reagent
2019 StandoutNatureNobel
NMR-based screening technologies
2003
Inhibitors of Protein Tyrosine Phosphatases: Next‐Generation Drugs?
2005
The Measure of All Rings—N‐Heterocyclic Carbenes
2010 Standout
Palladium Complexes of N‐Heterocyclic Carbenes as Catalysts for Cross‐Coupling Reactions—A Synthetic Chemist's Perspective
2007 Standout
Iron(III)‐Catalyzed and Air‐Mediated Tandem Reaction of Aldehydes, Alkynes and Amines: An Efficient Approach to Substituted Quinolines
2009
Probing the β2 Adrenoceptor Binding Site with Catechol Reveals Differences in Binding and Activation by Agonists and Partial Agonists
2005 StandoutNobel
Oral Glucocorticoid-Sparing Effect of Mepolizumab in Eosinophilic Asthma
2014 Standout
Introduction of Fluorine and Fluorine‐Containing Functional Groups
2013 Standout
Peptidomimetics derived from natural products
1993
Mice Deficient in Golf Are Anosmic
1998 StandoutNobel
Effect of bradykinin metabolism inhibitors on evoked hypotension in rats: rank efficacy of enzymes associated with bradykinin‐mediated angioedema
2007
Methods of using click chemistry in the discovery of enzyme inhibitors
2007
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Mechanisms involved in the side effects of glucocorticoids
2002 Standout
Hyperactivity and behavioral seizures in rodents following treatment with the dopamine D1 receptor agonists A-86929 and ABT-431
1996
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
PTP1B as a drug target: recent developments in PTP1B inhibitor discovery
2007
Stress and the brain: from adaptation to disease
2005 Standout
Overcoming mTOR resistance mutations with a new-generation mTOR inhibitor
2016 Nature
Phosphoinositide regulation of TRPV1 revisited
2015
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
2021 StandoutNobel
Transforming fragments into candidates: small becomes big in medicinal chemistry
2009
“Click” synthesis of small-molecule inhibitors targeting caspases
2008
Synthesis of new cis-fused tetrahydrochromeno[4,3-b]quinolines and their antiproliferative activity studies against MDA-MB-231 and MCF-7 breast cancer cell lines
2010
Features and development of Coot
2010 Standout
Angiotensin–Neprilysin Inhibition versus Enalapril in Heart Failure
2014 Standout
The Cross‐Dehydrogenative Coupling of CH Bonds: A Versatile Strategy for CC Bond Formations
2013 Standout
Discovery of nonsteroidal glucocorticoid receptor ligands based on 6-indole-1,2,3,4-tetrahydroquinolines
2008
Dopaminergic Supersensitivity in G Protein-Coupled Receptor Kinase 6-Deficient Mice
2003 StandoutNobel
The PI3K Pathway in Human Disease
2017 Standout
Fragment-based lead discovery: leads by design
2005
A decade of fragment-based drug design: strategic advances and lessons learned
2007
Nmr in drug discovery
2002 StandoutNobel
Binding Site Detection and Druggability Index from First Principles
2009
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Iron Catalysis in Organic Synthesis
2015 Standout
3d Transition Metals for C–H Activation
2018 Standout
Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design
1997 Standout
Synthesis of Heterocycles via Electrophilic Cyclization of Alkynes Containing Heteroatom
2011 Standout
Emergent Ion-Gated Binding of Cationic Host–Guest Complexes within Cationic M12L24 Molecular Flasks
2014 StandoutNobel
Inhibitoren der Proteintyrosinphosphatasen: Kandidaten für zukünftige Wirkstoffe?
2005
Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
2019 Standout
High-Throughput Discovery of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B (MptpB) Inhibitors Using Click Chemistry
2009
Engineering enzymes for noncanonical amino acid synthesis
2018 StandoutNobel
Click-Chemistry-Derived Triazole Ligands of Arginine−Glycine−Aspartate (RGD) Integrins with a Broad Capacity To Inhibit Adhesion of Melanoma Cells and Both in Vitro and in Vivo Angiogenesis
2010
Suzuki–Miyaura coupling with high turnover number using an N-acyl-N-heterocyclic carbene palladacycle precursor
2004
A Practical and Scaleable Synthesis of A-224817.0, a Novel Nonsteroidal Ligand for the Glucocorticoid Receptor
2003
Protein Pockets: Inventory, Shape, and Comparison
2010
Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1
2011 StandoutNobel
Efficient preparation of S-aryl thioacetates from aryl halides and potassium thioacetate
2007
The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases
2017 Standout
2-Chloro-2,2-difluoroacetophenone: A Non-ODS-Based Difluorocarbene Precursor and Its Use in the Difluoromethylation of Phenol Derivatives
2006
Advances in the Chemistry of Tetrahydroquinolines
2011 Standout
Organoselenium Chemistry: Role of Intramolecular Interactions
2010 Standout
Transition-Metal-Catalyzed C−S, C−Se, and C−Te Bond Formation via Cross-Coupling and Atom-Economic Addition Reactions
2011 Standout
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
Copper catalyzed room temperature lactonization of aromatic C–H bond: a novel and efficient approach for the synthesis of dibenzopyranones
2014
Negishi cross-couplings in the synthesis of amino acids
2017
Cascade Synthesis of 3-Quinolinecarboxylic Ester via Benzylation/ Propargylation−Cyclization
2008
Chemistry of Biologically Important Synthetic Organoselenium Compounds
2001 Standout
Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals
2011 Standout
Fluorosulfuryl Isocyanate Enabled SuFEx Ligation of Alcohols and Amines
2021 StandoutNobel
On the Value of c: Can Low Affinity Systems Be Studied by Isothermal Titration Calorimetry?
2003
DESENSITIZATION OF G PROTEIN–COUPLED RECEPTORS AND NEURONAL FUNCTIONS
2004 StandoutNobel
An Efficient Route to Quinolines and Other Compounds by Iron‐Catalysed Cross‐Dehydrogenative Coupling Reactions of Glycine Derivatives
2012
A Near-IR Reversible Fluorescent Probe Modulated by Selenium for Monitoring Peroxynitrite and Imaging in Living Cells
2011 Standout
Gold-Catalyzed Carbon−Heteroatom Bond-Forming Reactions
2011 Standout
Tethering Small Molecules to a Phage Display Library: Discovery of a Selective Bivalent Inhibitor of Protein Kinase A
2007
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Synthesis of dibenzopyranones and pyrazolobenzopyranones through copper(0)/Selectfluor system-catalyzed double CH activation/oxygen insertion of 2-arylbenzaldehydes and 5-arylpyrazole-4-carbaldehydes
2016
Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry
2020 StandoutNobel
Tyrosine Kinase Inhibitors. 6. Structure−Activity Relationships among N- and 3-Substituted 2,2‘-Diselenobis(1H-indoles) for Inhibition of Protein Tyrosine Kinases and Comparative in Vitro and in Vivo Studies against Selected Sulfur Congeners
1997
Rapid Assembly of Matrix Metalloprotease Inhibitors Using Click Chemistry
2006
Dopamine Receptors: From Structure to Function
1998 Standout
Organoselenium and Organotellurium Compounds: Toxicology and Pharmacology
2004 Standout
The Interplay between the Glucocorticoid Receptor and Nuclear Factor-κB or Activator Protein-1: Molecular Mechanisms for Gene Repression
2003
Synthesis of a Simplified Version of Stable Bulky and Rigid Cyclic (Alkyl)(amino)carbenes, and Catalytic Activity of the Ensuing Gold(I) Complex in the Three-Component Preparation of 1,2-Dihydroquinoline Derivatives
2009
Gold(I)-Catalyzed Activation of Alkynes for the Construction of Molecular Complexity
2015 Standout
Enantioselective Total Synthesis of Nigelladine A via Late-Stage C–H Oxidation Enabled by an Engineered P450 Enzyme
2017 StandoutNobel
Works of Michael A. Stashko being referenced
Identification of a monoacid-Based, cell permeable, selective inhibitor of protein tyrosine phosphatase 1B
2003
The Lipid Kinase PIP5K1C Regulates Pain Signaling and Sensitization
2014
Pyrrolidine-constrained phenethylamines: The design of potent, selective, and pharmacologically efficacious dipeptidyl peptidase IV (DPP4) inhibitors from a lead-like screening hit
2007
Differentiation of in vitro transcriptional repression and activation profiles of selective glucocorticoid modulators
2004
Cholecystokinin (CCK) antagonists: (R)-tryptophan-based hybrid antagonists of high affinity and selectivity for CCK-A receptors
1991
Characterization of cloned human dopamine D1 receptor-mediated calcium release in 293 cells.
1995
Selective Protein Tyrosine Phosphatase 1B Inhibitors: Targeting the Second Phosphotyrosine Binding Site with Non-Carboxylic Acid-Containing Ligands
2003
ABT-431: the diacetyl prodrug of A-86929, a potent and selective dopamine D1 receptor agonist: in vitro characterization and effects in animal models of Parkinson's disease.
1996
Nonsteroidal Selective Glucocorticoid Modulators: the Effect of C-5 Alkyl Substitution on the Transcriptional Activation/Repression Profile of 2,5-Dihydro-10-methoxy-2,2,4-trimethyl-1H-[1]benzopyrano[3,4-f]quinolines
2001
Nonsteroidal Selective Glucocorticoid Modulators: The Effect of C-10 Substitution on Receptor Selectivity and Functional Potency of 5-Allyl-2,5-dihydro-2,2,4-trimethyl-1H-[1]benzopyrano[3,4-f]quinolines
2003
Synthesis and Characterization of Non-Steroidal Ligands for the Glucocorticoid Receptor: Selective Quinoline Derivatives with Prednisolone-Equivalent Functional Activity
2001
Discovery of a Potent, Selective Protein Tyrosine Phosphatase 1B Inhibitor Using a Linked-Fragment Strategy
2003