Citation Impact
Citing Papers
Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases
2011 Standout
Molecular basis of MAPK-activated protein kinase 2:p38 assembly
2007
MicroRNA-155 is induced during the macrophage inflammatory response
2007 StandoutNobel
Switching from Repression to Activation: MicroRNAs Can Up-Regulate Translation
2007 StandoutScience
Disruption of MyD88 signaling suppresses hemophagocytic lymphohistiocytosis in mice
2011 StandoutNobel
Streptococcus pneumoniae stabilizes tumor necrosis factor α mRNA through a pathway dependent on p38 MAPK but independent of Toll-like receptors
2008
β-Arrestin-mediated Signaling Regulates Protein Synthesis
2008 StandoutNobel
The tandem CCCH zinc finger protein tristetraprolin and its relevance to cytokine mRNA turnover and arthritis.
2004
Interleukin-1 Receptor-associated Kinase 2 Is Critical for Lipopolysaccharide-mediated Post-transcriptional Control
2009
Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation
2015 StandoutNobel
Regulation of eukaryotic gene expression by the untranslated gene regions and other non-coding elements
2012
In situ click chemistry generation of cyclooxygenase-2 inhibitors
2017 Standout
Multilayered control of gene expression by stress‐activated protein kinases
2009
Involvement of Proton-Sensing TDAG8 in Extracellular Acidification-Induced Inhibition of Proinflammatory Cytokine Production in Peritoneal Macrophages
2009
Cyclooxygenase Isozymes: The Biology of Prostaglandin Synthesis and Inhibition
2004 Standout
A Lipid Peroxidation-derived Inflammatory Mediator
2004
Receptor-specific Ubiquitination of β-Arrestin Directs Assembly and Targeting of Seven-transmembrane Receptor Signalosomes
2005 StandoutNobel
Distinct Regulation of Cyclooxygenase-2 by Interleukin-1β in Normal and Endometriotic Stromal Cells
2005
Expression of COX-2 and PGE synthase and synthesis of PGE2 in endometrial adenocarcinoma: a possible autocrine/paracrine regulation of neoplastic cell function via EP2/EP4 receptors
2001
Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
2012 StandoutNature
Immediate-early MEK-1-dependent Stabilization of Rat Smooth Muscle Cell Cyclooxygenase-2 mRNA by Gαq-coupled Receptor Signaling
2000
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
2010 Standout
Wound healing and its impairment in the diabetic foot
2005 Standout
Rac1-MKK3-p38-MAPKAPK2 Pathway Promotes Urokinase Plasminogen Activator mRNA Stability in Invasive Breast Cancer Cells
2002
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Autoinhibitory Interdomain Interactions and Subfamily-specific Extensions Redefine the Catalytic Core of the Human DEAD-box Protein DDX3
2015 StandoutNobel
The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia
2017 StandoutNobel
N6-methyladenosine Modulates Messenger RNA Translation Efficiency
2015 Standout
Endometriosis
2009 Standout
Shared Principles in NF-κB Signaling
2008 Standout
Cross-talk between nuclear receptors and nuclear factor κB
2006
Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP-K2 and its interaction with cytokine mRNAs
2002
MK2‐induced tristetraprolin:14‐3‐3 complexes prevent stress granule association and ARE‐mRNA decay
2004
β-Arrestin 1 and Gαq/11 Coordinately Activate RhoA and Stress Fiber Formation following Receptor Stimulation
2004 StandoutNobel
Controlling gene expression in response to stress
2011
A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks
2015
MAPKAP kinases — MKs — two's company, three's a crowd
2006
MAPKAP kinase MK2 maintains self‐renewal capacity of haematopoietic stem cells
2009
Pattern Recognition Receptors and Inflammation
2010 Standout
TRANSCRIPTIONAL AND POST-TRANSCRIPTIONAL CONTROL OF GENE EXPRESSION IN INFLAMMATION
2002
Tristetraprolin Binds to the 3′-Untranslated Region of Cyclooxygenase-2 mRNA
2003
Mitogen activated protein kinase inhibitors: where are we now and where are we going?
2006
Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43
2009 StandoutNature
MAPKAP Kinase 2 Blocks Tristetraprolin-directed mRNA Decay by Inhibiting CAF1 Deadenylase Recruitment
2010
Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1
2001
The RNA-binding Protein HuR Regulates the Expression of Cyclooxygenase-2
2003
Regulation of Chemokine Expression by Antiinflammatory Cytokines
2002
MK2 and MK3 - a pair of isoenzymes?
2008
Platelet Activation and Atherothrombosis
2007 Standout
MyD88-mediated stabilization of interferon-γ-induced cytokine and chemokine mRNA
2006
Regulation of Ferroptotic Cancer Cell Death by GPX4
2014 Standout
MAPKAP Kinase 2 Phosphorylates Tristetraprolin on in Vivo Sites Including Ser178, a Site Required for 14-3-3 Binding
2004
The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism
1999
The AU-rich element mRNA decay-promoting activity of BRF1 is regulated by mitogen-activated protein kinase-activated protein kinase 2
2008
The 3′-Untranslated Region of Murine Cyclooxygenase-2 Contains Multiple Regulatory Elements That Alter Message Stability and Translational Efficiency
2001
Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
2010 Standout
Tracking and Elucidating Alphavirus-Host Protein Interactions
2006 StandoutNobel
Gαq signaling is required for Rho‐dependent transcriptional activation of the cyclooxygenase‐2 promoter in fibroblasts
2002
Combinations of ERK and p38 MAPK Inhibitors Ablate Tumor Necrosis Factor-α (TNF-α) mRNA Induction
2001
On the Dependency of Cellular Protein Levels on mRNA Abundance
2016 Standout
p38 MAP-Kinases pathway regulation, function and role in human diseases
2007
Post‐transcriptional regulation of gene expression by mitogen‐activated protein kinase p38
2003
From endoplasmic-reticulum stress to the inflammatory response
2008 StandoutNature
Production and Release of Neuroprotective Tumor Necrosis Factor by P2X7Receptor-Activated Microglia
2004
Specificity of signaling from MAPKs to MAPKAPKs: Kinases' Tango Nuevo
2008
M-Type Phospholipase A 2 Receptor as Target Antigen in Idiopathic Membranous Nephropathy
2009 Standout
The cap-to-tail guide to mRNA turnover
2001
Interleukin-10 targets p38 MAPK to modulate ARE-dependent TNF mRNA translation and limit intestinal pathology
2001
Free radicals and antioxidants in normal physiological functions and human disease
2006 Standout
HuR and mRNA stability
2001
MK2 Targets AU-rich Elements and Regulates Biosynthesis of Tumor Necrosis Factor and Interleukin-6 Independently at Different Post-transcriptional Levels
2002
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
Intracellular Signaling in Primary Sensory Neurons and Persistent Pain
2008
Mammalian MAP kinase signalling cascades
2001 StandoutNature
Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
2013 Standout
Post-transcriptional regulons coordinate the initiation and resolution of inflammation
2009
Genetics and pathogenesis of inflammatory bowel disease
2011 StandoutNature
Requirement for p38α in Erythropoietin Expression
2000
Free Cholesterol-loaded Macrophages Are an Abundant Source of Tumor Necrosis Factor-α and Interleukin-6
2005
The P2Y12 receptor regulates microglial activation by extracellular nucleotides
2006 StandoutNobel
Decreased mRNA Stability as a Mechanism of Glucocorticoid-Mediated Inhibition of Vascular Endothelial Growth Factor Gene Expression by Cultured Keratinocytes
2001
Positive regulation of immune cell function and inflammatory responses by phosphatase PAC-1
2006
Regulation of COX-2 Expression in Human Cancers
2003
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Post-transcriptional control of the interferon system
2007
Cyclooxygenase isozymes and their gene structures and expression
2002
Cancer-related inflammation
2008 StandoutNature
P66ShcA interacts with MAPKAP kinase 2 and regulates its activity
2004
The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling
2008
Toll-like receptor signalling pathways as key targets for mediating the anti-inflammatory and immunosuppressive effects of glucocorticoids
2003
Nociceptors: the sensors of the pain pathway
2010 StandoutNobel
MK2 regulates the early stages of skin tumor promotion
2009
Mechanisms of Dexamethasone-Mediated Inhibition of Toll-Like Receptor Signaling Induced byNeisseria meningitidisandStreptococcus pneumoniae
2007
Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses
2009 Standout
ERK and p38 MAPK-Activated Protein Kinases: a Family of Protein Kinases with Diverse Biological Functions
2004 Standout
Dexamethasone Causes Sustained Expression of Mitogen-Activated Protein Kinase (MAPK) Phosphatase 1 and Phosphatase-Mediated Inhibition of MAPK p38
2002
Cyclooxygenases: Structural, Cellular, and Molecular Biology
2000 Standout
SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase
2001 Standout
The Mitogen-Activated Protein Kinase (MAPK)-Activated Protein Kinases MK2 and MK3 Cooperate in Stimulation of Tumor Necrosis Factor Biosynthesis and Stabilization of p38 MAPK
2006
Regulation of Cyclooxygenase 2 mRNA Stability by the Mitogen-Activated Protein Kinase p38 Signaling Cascade
2000
Expression of COX-2 in platelet-monocyte interactions occurs via combinatorial regulation involving adhesion and cytokine signaling
2006
Cutting Edge: Priming of NK Cells by IL-18
2008 StandoutNobel
Protein Ligands to Hur Modulate Its Interaction with Target Mrnas in Vivo
2000
Macrophage glucocorticoid receptors regulate Toll-like receptor 4–mediated inflammatory responses by selective inhibition of p38 MAP kinase
2007
EGFR Activation Results in Enhanced Cyclooxygenase-2 Expression through p38 Mitogen-Activated Protein Kinase–Dependent Activation of the Sp1/Sp3 Transcription Factors in Human Gliomas
2007
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2001 StandoutScience
Critical roles of RNA helicase DDX3 and its interactions with eIF4E/PABP1 in stress granule assembly and stress response
2011
Control of the expression of inflammatory response genes
2003
PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
2003 StandoutNobel
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
Dexamethasone enhances LPS induction of tissue factor expression in human monocytic cells by increasing tissue factor mRNA stability
2004
von Hippel-Lindau Protein-Mediated Repression of Tumor Necrosis Factor Alpha Translation Revealed through Use of cDNA Arrays
2003
Proteomic Identification of 14-3-3ζ as a Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 Substrate: Role in Dimer Formation and Ligand Binding
2003
α3β1 integrin regulates MMP-9 mRNA stability in immortalized keratinocytes: a novel mechanism of integrin-mediated MMP gene expression
2005
Rapid transit in the immune cells: the role of mRNA turnover regulation
2007
p38 Mitogen-Activated Protein Kinase-Dependent and -Independent Signaling of mRNA Stability of AU-Rich Element-Containing Transcripts
2003
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
Signalling to translation: how signal transduction pathways control the protein synthetic machinery
2007
Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation
2001 Standout
Structure of the Sec23p/24p and Sec13p/31p complexes of COPII
2001 StandoutNobel
The Interplay between the Glucocorticoid Receptor and Nuclear Factor-κB or Activator Protein-1: Molecular Mechanisms for Gene Repression
2003
Pancreatic phospholipase A 2 via its receptor regulates the expression of key enzymes of phospholipid and sphingolipid metabolism
2001
Induction of Interleukin-8 Synthesis Integrates Effects on Transcription and mRNA Degradation from at Least Three Different Cytokine- or Stress-Activated Signal Transduction Pathways
1999
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Works of Matthew Brook being referenced
p38 Mitogen-activated Protein Kinase Regulates Cyclooxygenase-2 mRNA Stability and Transcription in Lipopolysaccharide-treated Human Monocytes
1999
The Stability of Tristetraprolin mRNA Is Regulated by Mitogen-activated Protein Kinase p38 and by Tristetraprolin Itself
2004
Regulation of tumour necrosis factor α mRNA stability by the mitogen‐activated protein kinase p38 signalling cascade
2000
A p38 MAP kinase inhibitor regulates stability of interleukin‐1‐induced cyclooxygenase‐2 mRNA
1998
Posttranslational Regulation of Tristetraprolin Subcellular Localization and Protein Stability by p38 Mitogen-Activated Protein Kinase and Extracellular Signal-Regulated Kinase Pathways
2006
Poly(A)-Binding Protein 1 Partially Relocalizes to the Nucleus during Herpes Simplex Virus Type 1 Infection in an ICP27-Independent Manner and Does Not Inhibit Virus Replication
2010
Dexamethasone Destabilizes Cyclooxygenase 2 mRNA by Inhibiting Mitogen-Activated Protein Kinase p38
2001
Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 Regulates Tumor Necrosis Factor mRNA Stability and Translation Mainly by Altering Tristetraprolin Expression, Stability, and Binding to Adenine/Uridine-Rich Element
2006
Mitogen-Activated Protein Kinase p38 Controls the Expression and Posttranslational Modification of Tristetraprolin, a Regulator of Tumor Necrosis Factor Alpha mRNA Stability
2001
Poly(A)-binding proteins are functionally distinct and have essential roles during vertebrate development
2011