Citation Impact
Citing Papers
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
2014 StandoutNatureNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Biophysical compensation mechanisms buffering E. coli protein–nucleic acid interactions against changing environments
1998
The dynamics of partially extended single molecules of DNA
1997 StandoutNatureNobel
Isolation and properties of transcribing ternary complexes of Escherichia coli RNA polymerase positioned at a single template base
1987
Nucleosome Positioning: Occurrence, Mechanisms, and Functional Consequences
1991
Crystal Structure of lac Repressor Core Tetramer and Its Implications for DNA Looping
1995 StandoutScienceNobel
Crystal structure of globular domain of histone H5 and its implications for nucleosome binding
1993 StandoutNatureNobel
The Influence of Macromolecular Crowding and Macromolecular Confinement on Biochemical Reactions in Physiological Media
2001 Standout
Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome
1999 StandoutNobel
Sequence-specific DNA binding by theMspl DNA methyltransferase
1992 StandoutNobel
Structural basis for initiation of transcription from an RNA polymerase–promoter complex
1999 StandoutNatureNobel
An initiation site for meiotic gene conversion in the yeast Saccharomyces cerevisiae
1989 StandoutNatureNobel
Synergy between Escherichia coli CAP protein and RNA polymerase in the lac promoter open complex
1989
Identification of silencer binding proteins from yeast: possible roles in SIR control and DNA replication
1987
A mediator required for activation of RNA polymerase II transcription in vitro
1991 StandoutNatureNobel
Noncovalent drug-DNA binding interactions that inhibit and stimulate (A)BC excinuclease
1991 StandoutNobel
Runaway telomere elongation caused by telomerase RNA gene mutations
1995 StandoutNatureNobel
Structure of human cyclophilin and its binding site for cyclosporin A determined by X-ray crystallography and NMR spectroscopy
1991 StandoutNatureNobel
The promoter-search mechanism of Escherichia coli RNA polymerase is dominated by three-dimensional diffusion
2012
Histone Function in Transcription
1990
Asp537, Asp812 are essential and Lys631, His811 are catalytically significant in bacteriophage T7 RNA polymerase activity
1992
Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins
1994 StandoutScience
Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats
1996 StandoutNatureNobel
DNA sequence determinants of CAP-induced bending and protein binding affinity
1988 Nature
Coordination of expression of DNA synthesis genes in budding yeast by a cell-cycle regulated trans factor
1991 Nature
DNA Bending Induced by the Catabolite Activator Protein Allows Ring Formation of a 144 bp DNA
1987
Computational redesign of endonuclease DNA binding and cleavage specificity
2006 StandoutNatureNobel
Lac repressor is a transient gene-activating protein
1987
Cell-permeant caged InsP3 ester shows that Ca2+ spike frequency can optimize gene expression
1998 StandoutNatureNobel
The interaction ofE.coliintegration host factor and λcosDNA: multiple complex formation and protein-induced bending
1989
Purification and cloning of a DNA binding protein from yeast that binds to both silencer and activator elements
1987
Nucleosome positioning as a critical determinant for the DNA cleavage sites of mammalian DNA topoisomerase in reconstituted Simian virus 40 chromatin
1990 StandoutNobel
Interferon-induced binding of nuclear factors to promoter elements of the 2-5A synthetase gene.
1988
Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity
2015 StandoutNatureNobel
Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation
1990 StandoutNatureNobel
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene
1996 StandoutNatureNobel
Mutations altering the cleavage specificity of a homing endonuclease
2002
Radioactive labeling of recombinant antibody fragments by phosphorylation using human casein kinase II and [γ-32P]-ATP
1996 StandoutNobel
Local Supercoil-Stabilized DNA Structure
1991
Identification of the different intermediates in the interaction of (A)BC excinuclease with its substrates by DNase I footprinting on two uniquely modified oligonucleotides
1991 StandoutNobel
Influence of excluded volume upon macromolecular structure and associations in ‘crowded” media
1997
Lysine 188 of the catabolite gene activator protein (CAP) plays no role in specificity at base pair 7 of the DNA half site
1990
Identification of a telomere-binding activity from yeast.
1986
Relaxation of a Single DNA Molecule Observed by Optical Microscopy
1994 StandoutScienceNobel
Purification and characterization of proteins that bind to yeast ARSs.
1988
Single cell assay of a transcription factor reveals a threshold in transcription activated by signals emanating from the T-cell antigen receptor.
1990
The locus of sequence-directed and protein-induced DNA bending
1984 StandoutNature
A cellular DNA-binding protein that activates eukaryotic transcription and DNA replication
1987
Distinct factors bind to apparently homolgous sequences in the immunoglobulin heavy-chain enhancer
1986 NatureNobel
Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin.
1990
Model of specific complex between catabolite gene activator protein and B-DNA suggested by electrostatic complementarity.
1984 StandoutNobel
Quantitation of Transcription and Clonal Selection of Single Living Cells with β-Lactamase as Reporter
1998 StandoutScienceNobel
On the different binding affinities of CRP at thelac, galandmalT promoter regions
1983
CAP and RNA polymerase interactions with thelacpromoter: binding stoichiometry and long range effects
1983
Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB Synthesis
1995 StandoutScience
Cyclic AMP Receptor Protein: Role in Transcription Activation
1984 Science
Identification of factors that interact with the E1A-inducible adenovirus E3 promoter.
1987
Specific interaction of cellular factors with the B enhancer of polyoma virus.
1985
Direct measurement of oligonucleotide substrate binding to wild-type and mutant ribozymes from Tetrahymena.
1990 Nobel
Inducible binding of a factor to the c-fos enhancer
1986
The adenovirus-inducible factor E2F stimulates transcription after specific DNA binding.
1989
Two interferon-induced nuclear factors bind a single promoter element in interferon-stimulated genes.
1988
Probing the sequence-specific interaction of the cyclic AMP receptor protein with DNA by site-directed mutagenesis
1987
The Oct-2 protein binds cooperatively to adjacent octamer sites.
1989
Structural Basis of Transcription: An RNA Polymerase II Elongation Complex at 3.3 Å Resolution
2001 StandoutScienceNobel
Isolation and sequence-specific DNA binding of the Antennapedia homeodomain.
1988 StandoutNobel
A protein binds to a satellite DNA repeat at three specific sites that would be brought into mutual proximity by DNA folding in the nucleosome
1984
Two DNA-binding factors recognize specific sequences at silencers, upstream activating sequences, autonomously replicating sequences, and telomeres in Saccharomyces cerevisiae.
1988 StandoutNobel
A general upstream binding factor for genes of the yeast translational apparatus.
1985
Yeast GCN4 transcriptional activator protein interacts with RNA polymerase II in vitro.
1989
The binding of the cyclic AMP receptor protein to synthetic DNA sites containing permutations in the consensus sequence TGTGA
1987
Molecular Matchmakers
1993 StandoutScienceNobel
Two DNA-Binding Factors Recognize Specific Sequences at Silencers, Upstream Activating Sequences, Autonomously Replicating Sequences, and Telomeres in Saccharomyces cerevisiae
1988 StandoutNobel
Cytoplasmic activation of ISGF3, the positive regulator of interferon-alpha-stimulated transcription, reconstituted in vitro.
1989
Synergistic interaction between interferon-alpha and interferon-gamma through induced synthesis of one subunit of the transcription factor ISGF3.
1990
Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative transcriptional control.
1988
Interaction of GAL4 and GAL80 Gene Regulatory Proteins In Vitro
1987 StandoutNobel
Kinetics and mechanism in the reaction of gene regulatory proteins with DNA
1984
Interferon gamma-induced transcription of the high-affinity Fc receptor for IgG requires assembly of a complex that includes the 91-kDa subunit of transcription factor ISGF3.
1993
Multiple nuclear factors interact with the immunoglobulin enhancer sequences
1986 StandoutNobel
D1 protein of Drosophila melanogaster. Purification and AT-DNA binding properties.
1985
Variations of intramolecular ligation rates allow the detection of protein-induced bends in DNA.
1986
GCN4 protein, synthesize in vitro, binds HIS3 regulatory sequences: Implications for general control of amino acid biosynthetic genes in yeast
1985
Crystal Structure of a CAP-DNA Complex: the DNA Is Bent by 90°
1991 StandoutScienceNobel
A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes
1986 NatureNobel
ISGF3, the transcriptional activator induced by interferon alpha, consists of multiple interacting polypeptide chains.
1990
Efficient intracellular delivery of biomacromolecules employing clusters of zinc oxide nanowires
2017
Sequences and Factors: A Guide to MHC Class-II Transcription
1992
Processive proofreading is intrinsic to T4 DNA polymerase.
1992
Maintenance of in Vivo Tolerance by Persistence of Antigen
1992 StandoutScienceNobel
The DNA binding domain and bending angle of E. coli CAP protein
1986
Activation of Transcription by IFN-γ: Tyrosine Phosphorylation of a 91-kD DNA Binding Protein
1992 Science
Specific DNA binding of the cAMP receptor protein within the lac operon stabilizes double-stranded DNA in the presence of cAMP.
1983
Ethylation interference and X-ray crystallography identify similar interactions between 434 repressor and operator
1985 Nature
lac repressor forms loops with linear DNA carrying two suitably spaced lac operators.
1987
Cooperative Interactions Between the Caenorhabditis elegans Homeoproteins UNC-86 and MEC-3
1993 StandoutScienceNobel
Cognate DNA Binding Specificity Retained After Leucine Zipper Exchange Between GCN4 and C/EBP
1989 StandoutScienceNobel
Identification and purification of a factor that binds to the Mlu I cell cycle box of yeast DNA replication genes.
1991 StandoutNobel
Mechanism of CRP-cAMP activation of lac operon transcription initiation activation of the P1 promoter
1984
Functional Significance of Cell Volume Regulatory Mechanisms
1998 Standout
Direct Observation of Tube-Like Motion of a Single Polymer Chain
1994 StandoutScienceNobel
Regulation of the Escherichia coli l-arabinose operon studied by gel electrophoresis DNA binding assay
1984
Structure of E. coli Glutaminyl-tRNA Synthetase Complexed with tRNA Gln and ATP at 2.8 Å Resolution
1989 StandoutScienceNobel
Structure and function of telomeres
1991 StandoutNatureNobel
DNA: A Model Compound for Solution Studies of Macromolecules
1991 Science
Regulation of the Ets-Related Transcription Factor Elf-1 by Binding to the Retinoblastoma Protein
1993 StandoutScienceNobel
Role of glutamic acid-181 in DNA-sequence recognition by the catabolite gene activator protein (CAP) of Escherichia coli: altered DNA-sequence-recognition properties of [Val181]CAP and [Leu181]CAP.
1987
An inducible transcription factor activates expression of human immunodeficiency virus in T cells
1987 StandoutNatureNobel
Selection of a Ribozyme That Functions as a Superior Template in a Self-Copying Reaction
1992 StandoutScienceNobel
Overlapping elements in the guanylate-binding protein gene promoter mediate transcriptional induction by alpha and gamma interferons.
1991
Fragments of the HIV-1 Tat Protein Specifically Biand TAR RNA
1990 StandoutScienceNobel
Defective Lymphoid Development in Mice Lacking Jak3
1995 StandoutScienceNobel
Interaction of GAL4 and GAL80 gene regulatory proteins in vitro.
1987 StandoutNobel
Demonstration of two operator elements in gal: in vitro repressor binding studies.
1984
Detection in vivo of protein-DNA interactions within the lac operon of Escherichia coli
1985 NatureNobel
Identification of a cellular transcription factor involved in E1A trans-activation
1986
Works of Mark M. Garner being referenced
Effect of Z-DNA on nucleosome placement
1987
Water release associated with specific binding of gal repressor.
1995
The use of gel electrophoresis to detect and study nucleic acid— protein interactions
1986
Stoichiometry of catabolite activator protein/adenosine cyclic 3',5'-monophosphate interactions at the lac promoter of Escherichia coli
1982
Macromolecular crowding and confinement in cells exposed to hypertonicity
1994
Effects of DNA supercoiling on the topological properties of nucleosomes.
1987
A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system
1981 Standout
Comparison of nucleic acid-protein interactions in solution and in polyacrylamide gels
1986
Self-diffusion and cooperative diffusion of a rodlike DNA fragment
1991
Interaction of catabolite activator protein of Escherichia coli with single-stranded deoxyribonucleic acid
1981