Citation Impact
Citing Papers
De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination
2003 StandoutNobel
A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression
2005 StandoutNobel
Evolution of new nonantibody proteins via iterative somatic hypermutation
2004 StandoutNobel
C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion
2014 StandoutNobel
AID Enzyme-Induced Hypermutation in an Actively Transcribed Gene in Fibroblasts
2002 StandoutScienceNobel
Correlation of somatic hypermutation specificity and A-T base pair substitution errors by DNA polymerase η during copying of a mouse immunoglobulin κ light chain transgene
2002
Molecular breeding of polymerases for amplification of ancient DNA
2007 StandoutNobel
Linking class-switch recombination with somatic hypermutation
2001 StandoutNobel
Emerging links between hypermutation of antibody genes and DNA polymerases
2001
AID and mismatch repair in antibody diversification
2002
DNA polymerase η is an A-T mutator in somatic hypermutation of immunoglobulin variable genes
2001
Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium
2007 StandoutNobel
Immunoglobulin Isotype Switching Is Inhibited and Somatic Hypermutation Perturbed in UNG-Deficient Mice
2002 StandoutNobel
Mepolizumab and Exacerbations of Refractory Eosinophilic Asthma
2009 Standout
AID Is Required for c-myc/IgH Chromosome Translocations In Vivo
2004 StandoutNobel
Separate domains of AID are required for somatic hypermutation and class-switch recombination
2004 StandoutNobel
Exploring the role of large conformational changes in the fidelity of DNA polymerase β
2007 StandoutNobel
Asthma
2017 Standout
A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations
2008 StandoutNobel
Evolving proteins in mammalian cells using somatic hypermutation
2006 StandoutNobel
Functions of human DNA polymerases η, κ and ι suggested by their properties, including fidelity with undamaged DNA templates
2003
Altered nucleotide misinsertion fidelity associated with poliota-dependent replication at the end of a DNA template
2001
What role for AID: mutator, or assembler of the immunoglobulin mutasome?
2003
Sequence analysis of light chain genes from human intestinal plasma cells demonstrates that lambda genes are almost all in-frame and highly mutated and most kappa genes are highly mutatedwhen in-frame and minimally mutated when out-of-frame
2000
Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas
2002 Nature
Activation‐Induced Cytidine Deaminase Links Class Switch Recombination and Somatic Hypermutation
2003 StandoutNobel
Requirement of Non-canonical Activity of Uracil DNA Glycosylase for Class Switch Recombination
2006 StandoutNobel
Somatic mutation hotspots correlate with DNA polymerase η error spectrum
2001
Expression of activation-induced cytidine deaminase in human hepatocytes via NF-κB signaling
2007 StandoutNobel
Aid
2004 StandoutNobel
Intestinal IgA synthesis: regulation of front-line body defences
2003 StandoutNobel
Effects of Sequence and Structure on the Hypermutability of Immunoglobulin Genes
2002
AID mutant analyses indicate requirement for class-switch-specific cofactors
2003 StandoutNobel
The Structural Mechanism of Translocation and Helicase Activity in T7 RNA Polymerase
2004 StandoutNobel
DNA polymerase mu (Pol micro), homologous to TdT, could act as a DNA mutator in eukaryotic cells
2000
Expression of human AID in yeast induces mutations in context similar to the context of somatic hypermutation at G-C pairs in immunoglobulin genes
2005
Organ‐specific profiles of genetic changes in cancers caused by activation‐induced cytidine deaminase expression
2008 StandoutNobel
Negative regulation of activation-induced cytidine deaminase in B cells
2006 StandoutNobel
Carboxy-terminal domain of AID required for its mRNA complex formation in vivo
2009 StandoutNobel
Accumulation of the FACT complex, as well as histone H3.3, serves as a target marker for somatic hypermutation
2013 StandoutNobel
Error-Prone Repair DNA Polymerases in Prokaryotes and Eukaryotes
2002
Decrease in topoisomerase I is responsible for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation
2011 StandoutNobel
Normal Somatic Hypermutation of Ig Genes in the Absence of 8-Hydroxyguanine-DNA Glycosylase
2003 StandoutNobel
A Computational Study of the Hydrolysis of dGTP Analogues with Halomethylene-Modified Leaving Groups in Solution: Implications for the Mechanism of DNA Polymerases
2009 StandoutNobel
Molecular Mechanism of Class Switch Recombination: Linkage with Somatic Hypermutation
2002 StandoutNobel
Unmutated Immunoglobulin M Can Protect Mice from Death by Influenza Virus Infection
2003 StandoutNobel
British Guideline on the Management of Asthma
2008
The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination
2009 StandoutNobel
PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance
2010 StandoutNobel
The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway
2010 Standout
Computer simulations of protein functions: Searching for the molecular origin of the replication fidelity of DNA polymerases
2005 StandoutNobel
The Targeting of Somatic Hypermutation Closely Resembles That of Meiotic Mutation
2001
Constitutive Expression of AID Leads to Tumorigenesis
2003 StandoutNobel
Modifying the β,γ Leaving-Group Bridging Oxygen Alters Nucleotide Incorporation Efficiency, Fidelity, and the Catalytic Mechanism of DNA Polymerase β
2006 StandoutNobel
DNA Double-Strand Breaks
2002 StandoutNobel
DNA cleavage in immunoglobulin somatic hypermutation depends onde novoprotein synthesis but not on uracil DNA glycosylase
2005 StandoutNobel
Dissociation of in vitro DNA deamination activity and physiological functions of AID mutants
2008 StandoutNobel
Evolutionary Comparison of the Mechanism of DNA Cleavage with Respect to Immune Diversity and Genomic Instability
2012 StandoutNobel
Recombinogenic Phenotype of Human Activation-Induced Cytosine Deaminase
2004
Variable deletion and duplication at recombination junction ends: Implication for staggered double-strand cleavage in class-switch recombination
2001 StandoutNobel
Activation-induced Deaminase (AID)-directed Hypermutation in the Immunoglobulin Sμ Region
2002 StandoutNobel
Interventions for educating children who are at risk of asthma-related emergency department attendance
2009
Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1
2004 StandoutNobel
Cutting Edge: DGYW/WRCH Is a Better Predictor of Mutability at G:C Bases in Ig Hypermutation Than the Widely Accepted RGYW/WRCY Motif and Probably Reflects a Two-Step Activation-Induced Cytidine Deaminase-Triggered Process
2004
DNA Breaks in Hypermutating Immunoglobulin Genes: Evidence for a Break-and-Repair Pathway of Somatic Hypermutation
2001
Clinical pathways: effects on professional practice, patient outcomes, length of stay and hospital costs
2010 Standout
Simulating the Effect of DNA Polymerase Mutations on Transition-State Energetics and Fidelity: Evaluating Amino Acid Group Contribution and Allosteric Coupling for Ionized Residues in Human Pol β
2006 StandoutNobel
DNA Polymerase η Contributes to Strand Bias of Mutations of A versus T in Immunoglobulin Genes
2005
RNA-editing cytidine deaminase Apobec-1 is unable to induce somatic hypermutation in mammalian cells
2003 StandoutNobel
AID to overcome the limitations of genomic information
2005 StandoutNobel
Works of Mark Dunn being referenced
Effect of an Integrated Care Pathway on Acute Asthma/Wheeze in Children Attending Hospital: Cluster Randomized Trial
2007
Characteristics of Sequences Around Individual Nucleotide Substitutions in IgVH Genes Suggest Different GC and AT Mutators
1999