Citation Impact
Citing Papers
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
2017 Standout
Fine Tuning of the UPR by the Ubiquitin Ligases Siah1/2
2014
Efficient Gene Delivery and Selective Transduction of Glial Cells in the Mammalian Brain by AAV Serotypes Isolated From Nonhuman Primates
2009
A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension
2019 StandoutNobel
Open questions for Alzheimer’s disease immunotherapy
2014
Interleukin-18 and IL-18 Binding Protein
2013
HIF Hydroxylase Pathways in Cardiovascular Physiology and Medicine
2015 StandoutNobel
Genetic Animal Models of Cerebral Vasculopathies
2011
Potent amyloidogenicity and pathogenicity of Aβ43
2011
Convection-enhanced delivery and systemic mannitol increase gene product distribution of AAV vectors 5, 8, and 9 and increase gene product in the adult mouse brain
2010
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
2016 StandoutNature
Synapses and Alzheimer's Disease
2012 StandoutNobel
Recent advances in our understanding of neurodegeneration
2009
Notch signalling in solid tumours: a little bit of everything but not all the time
2011
Microglia: active sensor and versatile effector cells in the normal and pathologic brain
2007 Standout
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
2016 StandoutNobel
Targeting Aβ and tau in Alzheimer's disease, an early interim report
2009
The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics
2011 Standout
N‐cadherin‐based adhesion enhances Aβ release and decreases Aβ42/40 ratio
2008
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies
2009
Roles of individual prolyl‐4‐hydroxylase isoforms in the first 24 hours following transient focal cerebral ischaemia: insights from genetically modified mice
2012 StandoutNobel
Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy
2012 Standout
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
2019 Standout
Efficient four‐drug cocktail therapy targeting amyloid‐β peptide for Alzheimer's disease
2010
Alzheimer's disease
2011 Standout
Interleukin-18, more than a Th1 cytokine
2013
microRNA-33 Regulates ApoE Lipidation and Amyloid-β Metabolism in the Brain
2015
AAV serotype 2/1-mediated gene delivery of anti-inflammatory interleukin-10 enhances neurogenesis and cognitive function in APP+PS1 mice
2011
The secretases: enzymes with therapeutic potential in Alzheimer disease
2010
Hippocampal expression of murine TNFα results in attenuation of amyloid deposition in vivo
2011
Robust Amyloid Clearance in a Mouse Model of Alzheimer's Disease Provides Novel Insights into the Mechanism of Amyloid-β Immunotherapy
2011
Parkinson's disease
2009 Standout
Animal models of human amyloidoses: Are transgenic mice worth the time and trouble?
2009
Partial Reduction of BACE1 Has Dramatic Effects on Alzheimer Plaque and Synaptic Pathology in APP Transgenic Mice
2007
Tau in physiology and pathology
2015 Standout
TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
2015 Standout
Immune attack: the role of inflammation in Alzheimer disease
2015 Standout
Sexual dimorphism in predisposition to Alzheimer's disease
2018
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Metazoan MicroRNAs
2018 Standout
Inhibition of Amyloid Formation
2012
Hypoxia inducible factor 1 (HIF-1) and cardioprotection
2010
A highly insoluble state of Aβ similar to that of Alzheimer's disease brain is found in Arctic APP transgenic mice
2008
Autophagy in Human Health and Disease
2013 Standout
Capillary pericytes regulate cerebral blood flow in health and disease
2014 StandoutNature
Mesoporous Silica Nanoparticles: Synthesis, Biocompatibility and Drug Delivery
2012 Standout
Alzheimer's disease
2016 Standout
Comparison of Aβ levels in the brain of familial and sporadic Alzheimer's disease
2009
Anti-Aβ Drug Screening Platform Using Human iPS Cell-Derived Neurons for the Treatment of Alzheimer's Disease
2011 StandoutNobel
The Role of Apolipoprotein E in Alzheimer's Disease
2009
Basic mechanisms of neurodegeneration: a critical update
2010
Survey of the year 2003 commercial optical biosensor literature
2004
Mechanisms and Functions of Inflammasomes
2014 Standout
The Amyloid State of Proteins in Human Diseases
2012 Standout
Direct in Vivo Intracellular Selection of Conformation-sensitive Antibody Domains Targeting Alzheimer's Amyloid-β Oligomers
2009
Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases
2012
Hippocampal expression of murine IL-4 results in exacerbation of amyloid deposition
2012
The Pathobiology of Vascular Dementia
2013 Standout
Mechanisms of disease: pulmonary arterial hypertension
2011
The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes
2012 Standout
Cortical α-synuclein load is associated with amyloid-β plaque burden in a subset of Parkinson’s disease patients
2008
Passive Immunization with Tau Oligomer Monoclonal Antibody Reverses Tauopathy Phenotypes without Affecting Hyperphosphorylated Neurofibrillary Tangles
2014
Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio
2010
Inflammasomes: mechanism of action, role in disease, and therapeutics
2015 Standout
A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease
2017 Standout
Single-cell transcriptomic analysis of Alzheimer’s disease
2019 StandoutNature
Optogenetics in Neural Systems
2011 Standout
The amyloid state and its association with protein misfolding diseases
2014 Standout
Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
2011 Standout
γ-Secretase and its modulators: Twenty years and beyond
2019
Monoclonal antibodies targeting IL-1 beta reduce biomarkers of atherosclerosis in vitro and inhibit atherosclerotic plaque formation in Apolipoprotein E-deficient mice
2011
Regulation of Hypoxia-induced Pulmonary Hypertension by Vascular Smooth Muscle Hypoxia-Inducible Factor-1α
2013
The amyloid hypothesis of Alzheimer's disease at 25 years
2016 Standout
The integrated stress response
2016 Standout
Neuroprotection by Dimethyloxalylglycine following Permanent and Transient Focal Cerebral Ischemia in Rats
2010
Clinical iron deficiency disturbs normal human responses to hypoxia
2016 StandoutNobel
Holdase activity of secreted Hsp70 masks amyloid-β42 neurotoxicity in Drosophila
2016
Control of inositol 1,4,5-trisphosphate-induced Ca2+ release by cytosolic Ca2+
1995 Standout
Interrelationship Between Cardiac Hypertrophy, Heart Failure, and Chronic Kidney Disease
2011
Qualitative changes in human γ-secretase underlie familial Alzheimer’s disease
2015
KEGG: integrating viruses and cellular organisms
2020 Standout
Fluorescence Lifetime Measurements and Biological Imaging
2010 Standout
Cytokine Storm
2020 Standout
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Alzheimer’s Disease: The Challenge of the Second Century
2011
Contributions of Amino Acid Side Chains to the Kinetics and Thermodynamics of the Bivalent Binding of Protein L to Ig κ Light Chain
2004 StandoutNobel
Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease
2020 Standout
Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease
2010
The mechanism of γ-Secretase dysfunction in familial Alzheimer disease
2012
Intracerebroventricular amyloid-β antibodies reduce cerebral amyloid angiopathy and associated micro-hemorrhages in aged Tg2576 mice
2009
Massive gliosis induced by interleukin‐6 suppresses Aβ deposition in vivo: evidence against inflammation as a driving force for amyloid deposition
2009
Water-Soluble Conjugated Polymers for Imaging, Diagnosis, and Therapy
2012 Standout
Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species
2008 Standout
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans -Golgi network
2012 StandoutNobel
Activation of Microglia Acidifies Lysosomes and Leads to Degradation of Alzheimer Amyloid Fibrils
2007
On the pivotal role of PPARa in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury
2016 StandoutNobel
HIF prolyl hydroxylase inhibition prior to transient focal cerebral ischaemia is neuroprotective in mice
2014
Works of Lisa Smithson being referenced
The stress response neuropeptide CRF increases amyloid‐β production by regulating γ‐secretase activity
2015
Chronic Pulmonary Artery Pressure Elevation Is Insufficient to Explain Right Heart Failure
2009
Novel rat Alzheimer's disease models based on AAV-mediated gene transfer to selectively increase hippocampal Aβ levels
2007
Intracranial Adeno-Associated Virus-Mediated Delivery of Anti-Pan Amyloid β, Amyloid β40, and Amyloid β42 Single-Chain Variable Fragments Attenuates Plaque Pathology in Amyloid Precursor Protein Mice
2006
Interleukin-1 receptor 1 knockout has no effect on amyloid deposition in Tg2576 mice and does not alter efficacy following Abeta immunotherapy.
2006
Cholestenoic acid, an endogenous cholesterol metabolite, is a potent γ-secretase modulator
2015
Interleukin-1 Trap Attenuates Cardiac Remodeling After Experimental Acute Myocardial Infarction in Mice
2010
Prolyl hydroxylase inhibition attenuates post-ischemic cardiac injury via induction of endoplasmic reticulum stress genes
2009
BRI2 (ITM2b) Inhibits A Deposition In Vivo
2008
Epidermal Growth Factor Receptor and Notch Pathways Participate in the Tumor Suppressor Function of γ-Secretase
2007
Aβ40 Inhibits Amyloid DepositionIn Vivo
2007
Interleukin‐1β modulation using a genetically engineered antibody prevents adverse cardiac remodelling following acute myocardial infarction in the mouse
2010
Insights into the mechanisms of action of anti‐Aβ antibodies in Alzheimer's disease mouse models
2006