Citation Impact
Citing Papers
Rhizobium induces DNA damage in Caenorhabditis elegans intestinal cells
2019 StandoutNobel
Systematic Genetic Analysis with Ordered Arrays of Yeast Deletion Mutants
2001 StandoutScience
PARP inhibitors: Synthetic lethality in the clinic
2017 StandoutScience
Mismatch Repair-dependent Iterative Excision at Irreparable O6-Methylguanine Lesions in Human Nuclear Extracts
2006 StandoutNobel
Human Mismatch Repair
2005 StandoutNobel
The Full-length Saccharomyces cerevisiae Sgs1 Protein Is a Vigorous DNA Helicase That Preferentially Unwinds Holliday Junctions
2010
Mapping the DNA Topoisomerase III Binding Domain of the Sgs1 DNA Helicase
2001
Mechanisms in Eukaryotic Mismatch Repair
2006 StandoutNobel
RECQ1 Helicase Interacts with Human Mismatch Repair Factors That Regulate Genetic Recombination*[boxs]
2005
The DNA-damage response in human biology and disease
2009 StandoutNature
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
2005 StandoutNature
The role of DNA damage and repair in aging through the prism of Koch-like criteria
2012
Poly(ADP-ribose) polymerase (PARP-1) has a controlling role in homologous recombination
2003
Reconstitution of initial steps of dsDNA break repair by the RecF pathway of E. coli
2009
p53: traffic cop at the crossroads of DNA repair and recombination
2005
RecQ helicases: multifunctional genome caretakers
2009
Rmi1 stimulates decatenation of double Holliday junctions during dissolution by Sgs1–Top3
2010
Replication Protein A Physically Interacts with the Bloom's Syndrome Protein and Stimulates Its Helicase Activity
2000
The β Sliding Clamp Binds to Multiple Sites within MutL and MutS
2006 StandoutNobel
Cellular roles of DNA topoisomerases: a molecular perspective
2002 Standout
Crystal structure of parallel quadruplexes from human telomeric DNA
2002 StandoutNature
Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae
2010 Nature
DNA topoisomerases: harnessing and constraining energy to govern chromosome topology
2008
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
Crystal Structure of Bacteriophage T4 5′ Nuclease in Complex with a Branched DNA Reveals How Flap Endonuclease-1 Family Nucleases Bind Their Substrates
2007
Biochemical Characterization of the DNA Helicase Activity of the Escherichia coli RecQ Helicase
2001
The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases
2001
Interaction of human DNA topoisomerase I with G-quartet structures
2000
The Processing of Holliday Junctions by BLM and WRN Helicases Is Regulated by p53
2002
Playing the End Game: DNA Double-Strand Break Repair Pathway Choice
2012
Human RECQ5β, a protein with DNA helicase and strand‐annealing activities in a single polypeptide
2004
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
2005 StandoutNature
DNA repair pathways as targets for cancer therapy
2008
The Bloom's Syndrome Protein (BLM) Interacts with MLH1 but Is Not Required for DNA Mismatch Repair
2001
The Exonucleolytic and Endonucleolytic Cleavage Activities of Human Exonuclease 1 Are Stimulated by an Interaction with the Carboxyl-terminal Region of the Werner Syndrome Protein
2003
Direct association of Bloom's syndrome gene product with the human mismatch repair protein MLH1
2001
Chromosomal stability and the DNA double-stranded break connection
2001
Endonucleolytic Function of MutLα in Human Mismatch Repair
2006 StandoutNobel
Functional Interaction of p53 and BLM DNA Helicase in Apoptosis
2001
Mismatch repair proteins: key regulators of genetic recombination
2004
Regulation of DNA double-strand break repair pathway choice
2007
Interaction between yeast Sgs1 helicase and DNA topoisomerase III
2000
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
The hepatitis C viral NS3 protein is a processive DNA helicase with cofactor enhanced RNA unwinding
2002
BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination
2003
RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO
2002 StandoutNature
Repair of Strand Breaks by Homologous Recombination
2013
Regulation of DNA repair throughout the cell cycle
2008
The Bloom's Syndrome Helicase Interacts Directly with the Human DNA Mismatch Repair Protein hMSH6
2003
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
Interplay between Structure-Specific Endonucleases for Crossover Control during Caenorhabditis elegans Meiosis
2013
Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
2010
The mismatch DNA repair heterodimer, hMSH2/6, regulates BLM helicase
2004 StandoutNobel
Analysis of helicase activity and substrate specificity of Drosophila RECQ5
2003
Search-and-replace genome editing without double-strand breaks or donor DNA
2019 StandoutNature
Human Claspin Is a Ring-shaped DNA-binding Protein with High Affinity to Branched DNA Structures
2004 StandoutNobel
Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
2008 Nature
DNA double-strand breaks: signaling, repair and the cancer connection
2001 Standout
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
Distinct Activities of Exonuclease 1 and Flap Endonuclease 1 at Telomeric G4 DNA
2010
Identification and Characterization of Human MUS81-MMS4 Structure-specific Endonuclease
2003 StandoutNobel
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Partial suppression of the fission yeast rqh1- phenotype by expression of a bacterial Holliday junction resolvase
2000
Sgs1 Helicase and Two Nucleases Dna2 and Exo1 Resect DNA Double-Strand Break Ends
2008
BLM–DNA2–RPA–MRN and EXO1–BLM–RPA–MRN constitute two DNA end resection machineries for human DNA break repair
2011 StandoutNobel
DNA end resection by Dna2–Sgs1–RPA and its stimulation by Top3–Rmi1 and Mre11–Rad50–Xrs2
2010 Nature
Conserved helicase domain of human RecQ4 is required for strand annealing-independent DNA unwinding
2010
Mechanisms of precise genome editing using oligonucleotide donors
2017
Functional overlap between Sgs1–Top3 and the Mms4–Mus81 endonuclease
2001
Human Mus81-Associated Endonuclease Cleaves Holliday Junctions In Vitro
2001
From meiosis to postmeiotic events: Homologous recombination is obligatory but flexible
2009
The Hallmarks of Aging
2013 Standout
Phosphorylation of H2AX at Short Telomeres in T Cells and Fibroblasts
2004 StandoutNobel
Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases
2012 StandoutNobel
DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs
2010 Standout
The NS5A Protein of Hepatitis C Virus Is a Zinc Metalloprotein
2004 StandoutNobel
Novel pro- and anti-recombination activities of the Bloom’s syndrome helicase
2007
DNA repair, mitochondria, and neurodegeneration
2006
Srs2 prevents Rad51 filament formation by repetitive motion on DNA
2013
BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges
2007
Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System
2015 StandoutNobel
Repair of Topoisomerase I‐Mediated DNA Damage
2006
PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair
2010 StandoutNobel
Chemical Topology: Complex Molecular Knots, Links, and Entanglements
2011 StandoutNobel
Mechanisms of double-strand break repair in somatic mammalian cells
2009
Ribozyme cleavage of telomerase mRNA sensitizes breast epithelial cells to inhibitors of topoisomerase.
2001
Srs2 and Sgs1 DNA Helicases Associate with Mre11 in Different Subcomplexes following Checkpoint Activation and CDK1-Mediated Srs2 Phosphorylation
2005
The puzzle of PCNA's many partners
2000
DNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial Inhibition
2009 Standout
Mechanism of Eukaryotic Homologous Recombination
2008
Inhibition of the Bloom's and Werner's Syndrome Helicases by G-Quadruplex Interacting Ligands
2001
Genes and pathways downstream of telomerase in melanoma metastasis
2006 StandoutNobel
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
2002 StandoutNobel
DNA Double-Strand Break Repair: All's Well that Ends Well
2006
Tumor Cell Death Induced by Topoisomerase-Targeting Drugs
2001
The human Bloom syndrome gene suppresses the DNA replication and repair defects of yeastdna2mutants
2003
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination
2009 StandoutNobel
DNA Helicases, Genomic Instability, and Human Genetic Disease
2000
Requirement for Three Novel Protein Complexes in the Absence of the Sgs1 DNA Helicase in Saccharomyces cerevisiae
2001
hMRE11 deficiency leads to microsatellite instability and defective DNA mismatch repair
2005
Genome-wide comprehensive analysis of human helicases
2011
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
The Bloom's syndrome gene product promotes branch migration of Holliday junctions
2000
WRN Helicase and FEN-1 Form a Complex upon Replication Arrest and Together Process Branchmigrating DNA Structures Associated with the Replication Fork
2003
Mice lacking DNA topoisomerase IIIβ develop to maturity but show a reduced mean lifespan
2001
DNA Repair in Drosophila
2000
megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering
2013 StandoutNobel
RNA Scanning of a Molecular Machine with a Built-in Ruler
2016 StandoutNobel
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
Simultaneous precise editing of multiple genes in human cells
2019 StandoutNobel
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
Interaction between Yeast Sgs1 Helicase and DNA Topoisomerase III
2000
Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair
2008 StandoutNobel
Human DNA Repair Genes
2001 StandoutScienceNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination
2010 StandoutNobel
The human Rad9–Rad1–Hus1 checkpoint complex stimulates flap endonuclease 1
2004 StandoutNobel
Structural Basis of Type II Topoisomerase Inhibition by the Anticancer Drug Etoposide
2011 StandoutScience
Genome-wide comprehensive analysis of human helicases.
2011
Bloom syndrome cells undergo p53-dependent apoptosis and delayed assembly of BRCA1 and NBS1 repair complexes at stalled replication forks
2003
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
Recombination-mediated lengthening of terminal telomeric repeats requires the Sgs1 DNA helicase
2001
Regulation of Homologous Recombination in Eukaryotes
2010
Reconstitution of Human DNA Polymerase δ Using Recombinant Baculoviruses
2002
Works of Leonard Wu being referenced
The Bloom's Syndrome Gene Product Interacts with Topoisomerase III
2000
The Bloom's Syndrome Helicase Can Promote the Regression of a Model Replication Fork
2006
Functional Interaction between the Bloom's Syndrome Helicase and the RAD51 Paralog, RAD51L3 (RAD51D)
2003
Roles of RecQ Family Helicases in the Maintenance of Genome Stability
2000
Potential Role for the BLM Helicase in Recombinational Repair via a Conserved Interaction with RAD51
2001
RecQ helicases and topoisomerases: components of a conserved complex for the regulation of genetic recombination
2001
Mph1 requires mismatch repair-independent and -dependent functions of MutSα to regulate crossover formation during homologous recombination repair
2010
Stimulation of Flap Endonuclease-1 by the Bloom's Syndrome Protein
2004
RecQ family helicases: roles in cancer and aging
2000
RecQ helicases and cellular responses to DNA damage
2002
Genetic recombination: Helicases and topoisomerases link up
1999
Overlapping Roles for Yen1 and Mus81 in Cellular Holliday Junction Processing
2010
The Bloom's syndrome helicase suppresses crossing over during homologous recombination
2003 Nature
The HRDC domain of BLM is required for the dissolution of double Holliday junctions
2005
DNA Helicases Required for Homologous Recombination and Repair of Damaged Replication Forks
2006
BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates
2006
DNA Ends RecQ-uire Attention
2001 Science
Roles of the Bloom's syndrome helicase in the maintenance of genome stability
2005
Roles of the Bloom's syndrome helicase in the maintenance of genome stability
2005