Citation Impact
Citing Papers
CRISPR–Cas9 Structures and Mechanisms
2017 StandoutNobel
MicroRNA-mediated gene regulation and the resilience of multicellular animals
2024 StandoutNobel
CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus
2015 StandoutNatureNobel
ASL mRNA-LNP Therapeutic for the Treatment of Argininosuccinic Aciduria Enables Survival Benefit in a Mouse Model
2023 StandoutNobel
Ferroptosis: molecular mechanisms and health implications
2020 Standout
Engineering adeno-associated viruses for clinical gene therapy
2014
Superior In vivo Transduction of Human Hepatocytes Using Engineered AAV3 Capsid
2016 StandoutNobel
In Vivo Selection Yields AAV-B1 Capsid for Central Nervous System and Muscle Gene Therapy
2016
Pharmacology and Management of the Vitamin K Antagonists
2008 Standout
Emerging and receding risks of therapeutic regimens for haemophilia
2004
Non-viral gene delivery in skeletal muscle: a protein factory
2003
Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation
2005 Standout
mRNA vaccines — a new era in vaccinology
2018 StandoutNobel
Gene therapy for neurological disorders: progress and prospects
2018
Cancer nanomedicine: progress, challenges and opportunities
2016 Standout
Off-target-free gene delivery by affinity-purified receptor-targeted viral vectors
2015
Plasma S/R ratio of warfarin co-varies with VKORC1 haplotype
2007 StandoutNobel
Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain
2016
Cloning of Rat Vitamin K-Dependent γ-Glutamyl Carboxylase and Developmentally Regulated Gene Expression in Postimplantation Embryos
1998
Bacterial CRISPR/Cas DNA endonucleases: A revolutionary technology that could dramatically impact viral research and treatment
2015
Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2
2004 StandoutNature
Identification of T-cell epitopes in clotting factor IX and lack of tolerance in inbred mice
2003
Hepatocyte-secreted DPP4 in obesity promotes adipose inflammation and insulin resistance
2018 Nature
Oral Anticoagulant Therapy
2012 Standout
AAV-Mediated Delivery of Zinc Finger Nucleases Targeting Hepatitis B Virus Inhibits Active Replication
2014
Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects
2020 Standout
Applications of CRISPR-Cas Enzymes in Cancer Therapeutics and Detection
2018 StandoutNobel
Combined genetic profiles of components and regulators of the vitamin K-dependent γ-carboxylation system affect individual sensitivity to warfarin
2006
Increased Erythropoiesis in Mice Injected With Submicrogram Quantities of Pseudouridine-containing mRNA Encoding Erythropoietin
2012 StandoutNobel
Targeting hepatitis B virus cccDNA by CRISPR/Cas9 nuclease efficiently inhibits viral replication
2015
Design and Synthesis of a Homogeneous Erythropoietin Analogue with Two Human Complex‐Type Sialyloligosaccharides: Combined Use of Chemical and Bacterial Protein Expression Methods
2009 StandoutNobel
Snakebite envenoming
2017 Standout
Common genetic variants of microsomal epoxide hydrolase affect warfarin dose requirements beyond the effect of cytochrome P450 2C9
2005
Evolution of a designed protein assembly encapsulating its own RNA genome
2017 StandoutNatureNobel
Mechanisms of NAFLD development and therapeutic strategies
2018 Standout
Hepatocyte TAZ/WWTR1 Promotes Inflammation and Fibrosis in Nonalcoholic Steatohepatitis
2016
The intriguing world of prothrombin activators from snake venom
2005
Non-alcoholic fatty liver disease
2021 Standout
Next-generation regulatory T cell therapy
2019
A translationally optimized AAV-UGT1A1 vector drives safe and long-lasting correction of Crigler-Najjar syndrome
2016
Promise and problems associated with the use of recombinant AAV for the delivery of anti-HIV antibodies
2016
Genome Engineering Using Adeno-associated Virus: Basic and Clinical Research Applications
2015
Lymphangiogenic growth factors, receptors and therapies
2003
Immune-orthogonal orthologues of AAV capsids and of Cas9 circumvent the immune response to the administration of gene therapy
2019
Cleavage of spike protein of SARS coronavirus by protease factor Xa is associated with viral infectivity
2007
Induction of immune tolerance to coagulation factor IX antigen by in vivo hepatic gene transfer
2003
Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation
2019
Vector Design Tour de Force: Integrating Combinatorial and Rational Approaches to Derive Novel Adeno-associated Virus Variants
2014
Common VKORC1 and GGCX polymorphisms associated with warfarin dose
2005
Diverse Viruses Require the Calcium Transporter SPCA1 for Maturation and Spread
2017 StandoutNobel
Scalable Downstream Strategies for Purification of Recombinant Adeno- Associated Virus Vectors in Light of the Properties
2015
The potential of adeno-associated viral vectors for gene delivery to muscle tissue
2014
In Silico Reconstruction of the Viral Evolutionary Lineage Yields a Potent Gene Therapy Vector
2015
A genotyping method for VKORC1 1173C>T by Pyrosequencing®technology
2008 StandoutNobel
Progress and problems with the use of viral vectors for gene therapy
2003 Standout
Post-translational modifications in the context of therapeutic proteins
2006
Adeno-associated virus vector as a platform for gene therapy delivery
2019 Standout
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus
2015 StandoutNobel
The roles of microRNAs in mouse development
2021
Postsynthetic modification of metal–organic frameworks
2009 Standout
Extensive double humanization of both liver and hematopoiesis in FRGN mice
2014
Single point mutation in adeno-associated viral vectors -DJ capsid leads to improvement for gene delivery in vivo
2016
Ferroptosis: mechanisms, biology and role in disease
2021 Standout
Factor Xa as an interface between coagulation and inflammation. Molecular mimicry of factor Xa association with effector cell protease receptor-1 induces acute inflammation in vivo.
1997
Promoterless gene targeting without nucleases ameliorates haemophilia B in mice
2014 Nature
Safe and Efficient Silencing with a Pol II, but Not a Pol lII, Promoter Expressing an Artificial miRNA Targeting Human Huntingtin
2017
An essential receptor for adeno-associated virus infection
2016 Nature
In Vivo Hepatic Reprogramming of Myofibroblasts with AAV Vectors as a Therapeutic Strategy for Liver Fibrosis
2016
Opportunities for Treg cell therapy for the treatment of human disease
2023 StandoutNobel
Main haplotypes and mutational analysis of vitamin K epoxide reductase (VKORC1) in a Swedish population: a retrospective analysis of case records
2006 StandoutNobel
Emerging Issues in AAV-Mediated In Vivo Gene Therapy
2017
Gene therapy returns to centre stage
2015 Nature
Humanized mice efficiently engrafted with fetal hepatoblasts and syngeneic immune cells develop human monocytes and NK cells
2016 StandoutNobel
Genome-editing Technologies for Gene and Cell Therapy
2016
Unraveling the Complex Story of Immune Responses to AAV Vectors Trial After Trial
2017
Safe and Effective In Vivo Targeting and Gene Editing in Hematopoietic Stem Cells: Strategies for Accelerating Development
2021 StandoutNobel
Adeno-Associated Virus Gene Therapy for Liver Disease
2016
Update on management of diabetic foot ulcers
2018 Standout
Induction and role of regulatory CD4+CD25+ T cells in tolerance to the transgene product following hepatic in vivo gene transfer
2007
Erratum: Gene therapy for neurological disorders: progress and prospects
2018
Taking regulatory T cells into medicine
2021 StandoutNobel
Correction of factor IX deficiency in mice by embryonic stem cells differentiated in vitro
2005 StandoutNobel
State-of-the-art human gene therapy: part I. Gene delivery technologies.
2015
Congenital Deficiency of Vitamin K Dependent Coagulation Factors in Two Families Presents as a Genetic Defect of the Vitamin K-Epoxide-Reductase-Complex
2000
The Vitamin K-dependent Carboxylase
2002
In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease
2017 StandoutNobel
Semisynthesis of Erythropoietin Analog Having Three Oligosaccharides
2011 StandoutNobel
Visualization of Positive and Negative Sense Viral RNA for Probing the Mechanism of Direct-Acting Antivirals against Hepatitis C Virus
2019 StandoutNobel
Autoimmune anemia in macaques following erythropoietin gene therapy
2004
Elucidating the Function of Complex‐Type Oligosaccharides by Use of Chemical Synthesis of Homogeneous Glycoproteins
2011 StandoutNobel
The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions
2005 Standout
The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders
2011 Standout
Improving the Quality of Adeno-Associated Viral Vector Preparations: The Challenge of Product-Related Impurities
2017
Design and Synthesis of a Homogeneous Erythropoietin Analogue with Two Human Complex‐Type Sialyloligosaccharides: Combined Use of Chemical and Bacterial Protein Expression Methods
2009 StandoutNobel
Viral Vectors for Gene Therapy: Translational and Clinical Outlook
2015
A new adenoviral helper–dependent vector results in long-term therapeutic levels of human coagulation factor IX at low doses in vivo
2002
COVID-19 and its implications for thrombosis and anticoagulation
2020 Standout
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
A Cell-based Model of Hemostasis
2001 Standout
GATA-4 and GATA-6 Modulate Tissue-Specific Transcription of the Human Gene for P450c17 by Direct Interaction with Sp1
2004
Coevolution of Adeno-associated Virus Capsid Antigenicity and Tropism through a Structure-Guided Approach
2020
γ-Glutamyl carboxylation: An extracellular posttranslational modification that antedates the divergence of molluscs, arthropods, and chordates
2002
Mechanisms of Renal Fibrosis
2017 Standout
Induction of antigen-specific CD4+ T-cell anergy and deletion by in vivo viral gene transfer
2004
Hepatitis C virus double‐stranded RNA is the predominant form in human liver and in interferon‐treated cells
2016
Guidelines for the management of hemophilia
2012 Standout
Systemic delivery of antisense oligoribonucleotide restores dystrophin expression in body-wide skeletal muscles
2004 StandoutNobel
Induction of immune tolerance to coagulation factor IX antigen by in vivo hepatic gene transfer
2003
Works of Kirk Chu being referenced
Activation-dependent Exposure of the Inter-EGF Sequence Leu83-Leu88 in Factor Xa Mediates Ligand Binding to Effector Cell Protease Receptor-1
1997
Selection and evaluation of clinically relevant AAV variants in a xenograft liver model
2013 Nature
Risk and Prevention of Anti-factor IX Formation in AAV-Mediated Gene Transfer in the Context of a Large Deletion of F9
2001
RNA interference–induced hepatotoxicity results from loss of the first synthesized isoform of microRNA-122 in mice
2016
miR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression
2018
The anti-genomic (negative) strand of Hepatitis C Virus is not targetable by shRNA
2013
Somatic Correction of Junctional Epidermolysis Bullosa by a Highly Recombinogenic AAV Variant
2014
Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity
2017
A 5′ Noncoding Exon Containing Engineered Intron Enhances Transgene Expression from Recombinant AAV Vectors in vivo
2016
Regulation of human coagulation factor X gene expression by GATA-4 and the Sp family of transcription factors
2001
Posttranslational modifications of recombinant myotube-synthesized human factor IX
2001
Genomic Sequence and Transcription Start Site for the Human γ-Glutamyl Carboxylase
1997
A concept of eliminating nonhomologous recombination for scalable and safe AAV vector generation for human gene therapy
2013