Citation Impact
Citing Papers
Phenotypic and functional features of human Th17 cells
2007 Standout
Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction
2006
The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring
2016 StandoutScience
Reciprocal T H 17 and Regulatory T Cell Differentiation Mediated by Retinoic Acid
2007 StandoutScience
Suppression of bone resorption by madindoline A, a novel nonpeptide antagonist to gp130
2002 StandoutNobel
Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model
2007 StandoutNobel
Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses
2007
Vaccination against IL‐17 suppresses autoimmune arthritis and encephalomyelitis
2006
Cytokines and direct cell contact in synovitis: relevance to therapeutic intervention.
1999
The stem cell niches in bone
2006
The complexities of skeletal biology
2003 StandoutNature
Interleukin-17 family and IL-17 receptors
2003
The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins
2008 StandoutNature
The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells
2006 Standout
Psoriasis
2009 Standout
Antigen-Specific T Cell Sensitization Is Impaired in IL-17-Deficient Mice, Causing Suppression of Allergic Cellular and Humoral Responses
2002
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Unravelling the pathogenesis of inflammatory bowel disease
2007 StandoutNature
Pathogenesis and therapy of psoriasis
2007 StandoutNature
Regulation of Receptor Activator of NF-κB Ligand-induced Osteoclastogenesis by Endogenous Interferon-β (INF-β) and Suppressors of Cytokine Signaling (SOCS)
2002
Cancer Metastasis: Building a Framework
2006 Standout
Autoimmune inflammation from the Th17 perspective
2006
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Reaching a Genetic and Molecular Understanding of Skeletal Development
2002 Standout
IL-4 gene therapy for collagen arthritis suppresses synovial IL-17 and osteoprotegerin ligand and prevents bone erosion
2000
Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria
2009 Standout
Effect of interleukin 17 on proteoglycan degradation in murine knee joints
2000
Coordinated cytokine expression by stromal and hematopoietic cells during human osteoclast formation
2000
The Pathogenesis of Rheumatoid Arthritis
2011 Standout
Inflammatory Bowel Disease
2009 Standout
Involvement of p38 Mitogen-activated Protein Kinase Signaling Pathway in Osteoclastogenesis Mediated by Receptor Activator of NF-κB Ligand (RANKL)
2000
PATHWAYS BY WHICH INTERLEUKIN 17 INDUCES ARTICULAR CARTILAGE BREAKDOWN IN VITRO AND IN VIVO
2001
Divergent effects of IL‐12 and IL‐23 on the production of IL‐17 by human T cells
2006
The bone marrow niche for haematopoietic stem cells
2014 StandoutNature
Overexpression of IL-17 in the knee joint of collagen type II immunized mice promotes collagen arthritis and aggravates joint destruction
2002
Interleukin-17 Production in Central Nervous System-Infiltrating T Cells and Glial Cells Is Associated with Active Disease in Multiple Sclerosis
2007
Evolving concepts of rheumatoid arthritis
2003 StandoutNature
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
2006 StandoutNature
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
2003 StandoutNatureNobel
TNFα and PTH utilize distinct mechanisms to induce IL-6 and RANKL expression with markedly different kinetics
2005
Peripheral blood T lymphocytes from patients with early rheumatoid arthritis express RANKL and interleukin‐15 on the cell surface and promote osteoclastogenesis in autologous monocytes
2006
IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding
2001
Intrathecal activation of the IL-17/IL-8 axis in opticospinal multiple sclerosis
2005
High in vivo expression of interleukin‐17 receptor in synovial endothelial cells and chondrocytes from arthritis patients
2001
Evidence that cytokines play a role in rheumatoid arthritis
2008
SLAM Family Receptors Distinguish Hematopoietic Stem and Progenitor Cells and Reveal Endothelial Niches for Stem Cells
2005 Standout
Systemic Lupus Erythematosus
2011 Standout
Induction of cartilage damage by overexpression of T cell interleukin‐17A in experimental arthritis in mice deficient in interleukin‐1
2005
The role of T-cell interleukin-17 in conducting destructive arthritis: lessons from animal models.
2005
IL-17E, a Novel Proinflammatory Ligand for the IL-17 Receptor Homolog IL-17Rh1
2001
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
2010 StandoutNature
Denosumab for Prevention of Fractures in Postmenopausal Women with Osteoporosis
2009 Standout
Osteoclast differentiation and activation
2003 StandoutNature
Interleukin‐17 in rheumatoid arthritis: If T cells were to contribute to inflammation and destruction through synergy
2003
Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone
2014 StandoutNature
Interleukin-23 Promotes a Distinct CD4 T Cell Activation State Characterized by the Production of Interleukin-17
2003 Standout
Interleukin‐6 modulates production of T lymphocyte–derived cytokines in antigen‐induced arthritis and drives inflammation‐induced osteoclastogenesis
2005
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Transgenic mice overexpressing soluble osteoclast differentiation factor (sODF) exhibit severe osteoporosis
2002
Th17 Cell Differentiation: The Long and Winding Road
2008
Progress and challenges in translating the biology of atherosclerosis
2011 StandoutNature
Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell–mediated spontaneous autoimmune arthritis in mice
2004 StandoutNobel
Mechanisms of Bone Metastasis
2004 Standout
Cytokines in the pathogenesis of rheumatoid arthritis
2007 Standout
Attenuated atherosclerosis upon IL-17R signaling disruption in LDLr deficient mice
2009
Interleukin-17: a mediator of inflammatory responses
2004
Chapter 5 Emergence of the Th17 Pathway and Its Role in Host Defense
2008
TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function
2008 StandoutNature
Understanding the IL-23–IL-17 immune pathway
2005
Lessons from animal models of arthritis
2002
Frailty in elderly people
2013 Standout
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
2005 StandoutNature
Skin-Resident T Cells: The Ups and Downs of On Site Immunity
2009
Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
2006 StandoutNature
Osteoblasts in prostate cancer metastasis to bone
2005
An essential role for IL-17 in preventing pathogen-initiated bone destruction: recruitment of neutrophils to inflamed bone requires IL-17 receptor–dependent signals
2007
Strontium can increase some osteoblasts without increasing hematopoietic stem cells
2007
Human Th17 Cells Share Major Trafficking Receptors with Both Polarized Effector T Cells and FOXP3+ Regulatory T Cells
2008
Bone Resorption by Osteoclasts
2000 StandoutScience
Interleukin 15: biology and relevance to human disease
2001
Emerging new roles of Th17 cells
2012
Osteoclasts and Arthritis
2009
Hematopoiesis is severely altered in mice with an induced osteoblast deficiency
2004
IL-17 and Th17 Cells
2009 Standout
Human Dendritic Cells Activate Resting Natural Killer (NK) Cells and Are Recognized via the NKp30 Receptor by Activated NK Cells
2002 StandoutNobel
IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist
2003
IL-17 Stimulates Intraperitoneal Neutrophil Infiltration Through the Release of GROα Chemokine from Mesothelial Cells
2000
Polymorphisms in the Osteoprotegerin Gene Are Associated With Osteoporotic Fractures
2002
Microbial Lipopeptides Induce the Production of IL-17 in Th Cells
2000
Gene expression profiling of multiple myeloma reveals molecular portraits in relation to the pathogenesis of the disease
2003
Cytokine Storm
2020 Standout
Association of CD4+CD25+T Cells with Prevention of Severe Destructive Arthritis inBorrelia burgdorferi-Vaccinated and Challenged Gamma Interferon-Deficient Mice Treated with Anti-Interleukin-17 Antibody
2004
IL-17: prototype member of an emerging cytokine family
2002
Exercise and Toll-like receptors.
2006
Cutting Edge: IL-17F, a Novel Cytokine Selectively Expressed in Activated T Cells and Monocytes, Regulates Angiogenesis and Endothelial Cell Cytokine Production
2001
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
2014 StandoutScienceNobel
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17
2007
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+regulatory T cells, evoking antitumor immune responses in humans
2013 StandoutNobel
Stimulation of osteoprotegerin production is responsible for osteosclerosis in mice overexpressing TPO
2003
Interleukin-17 Acts Independently of TNF-α under Arthritic Conditions
2006
Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell–mediated spontaneous autoimmune arthritis in mice
2004 StandoutNobel
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
2022 StandoutNobel
Interleukin‐17: the missing link between T‐cell accumulation and effector cell actions in rheumatoid arthritis?
2004
Requirement of Tumor Necrosis Factor Receptor–Associated Factor (Traf)6 in Interleukin 17 Signal Transduction
2000
IL-23 is essential for T cell–mediated colitis and promotes inflammation via IL-17 and IL-6
2006
IL-17 Promotes Bone Erosion in Murine Collagen-Induced Arthritis Through Loss of the Receptor Activator of NF-κB Ligand/Osteoprotegerin Balance
2003
Therapeutic Approaches to Bone Diseases
2000 Science
c-myc Is Required for Osteoclast Differentiation
2002
T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17+ Th cells that cause autoimmune arthritis
2007 StandoutNobel
Works of Kanami Itoh being referenced
Osteoblasts/stromal cells stimulate osteoclast activation through expression of osteoclast differentiation factor/RANKL but not macrophage colony-stimulating factor
1999
IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis
1999
Importance of Membrane- or Matrix-Associated Forms of M-CSF and RANKL/ODF in Osteoclastogenesis Supported by SaOS-4/3 Cells Expressing Recombinant PTH/PTHrP Receptors
2000
Lipopolysaccharide Promotes the Survival of Osteoclasts Via Toll-Like Receptor 4, but Cytokine Production of Osteoclasts in Response to Lipopolysaccharide Is Different from That of Macrophages
2003
Osteoprotegerin Produced by Osteoblasts Is an Important Regulator in Osteoclast Development and Function*
2000
p38 MAPK-Mediated Signals Are Required for Inducing Osteoclast Differentiation But Not for Osteoclast Function
2002
Transforming Growth Factor β Affects Osteoclast Differentiation via Direct and Indirect Actions
2001